ACLS Guidelines 2015
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1 ACLS Guidelines 2015 Wanda Rivera Bou MD, FAAEM, FACEP Assistant Professor Department of Emergency Medicine University of Puerto Rico School of Medicine AHA - ACLS National Faculty
2 Disclosure Information Wanda Rivera Bou, MD I have no financial relationships with drug or device manufacturing companies
3 Objectives: Will discuss n Identify the ACLS 2015 science updates n Describe the rationale for the science updates n Therapeutic interventions
4 International Liaison Committee on Resuscitation
5 Highlights of the 2015 AHA Guidelines Update for CPR and ECC
6 New AHA Adult Chains of Survival IN-HOSPITAL (note new Surveillance and Prevention link) OUT OF HOSPITAL Including EMS
7 Adult BLS and CPR Quality n There is continued emphasis on the characteristics of high-quality CPR: l compressing the chest at an adequate rate and depth l l allowing complete chest recoil after each compression minimizing interruptions in compressions l avoiding excessive ventilation
8 Chest Compression Rate n It is reasonable to perform compressions at a rate of /min Metronome ü Observational study ü Dec, 2005 May, 2007 ü Sharp decline in survival with rate > 140/min Idris A.H et al, Circulation. 2012;125:
9
10
11 Rapid Compression Rate can Compromise Depth Idris et al, Critical Care Medicine, 2015:43 (4): 840
12 Chest Compression Depth n Chest compression to at least 2 inches (5 cm), avoiding chest compression depths > 2.4 inches (6 cm) Small study: more injuries with compressions greater than 2.4 inches (6cm). (Hellevuo et al, Resuscitation, 2013) Difficult to judge depth without devices Rescuers typically don t push hard enough Stiell I.G et al, Circulation. 2014;130:
13 BLS for HCP Highlights of the 2015 AHA Guidelines Update for CPR and ECC
14 For BLS and ACLS algorithms, please referred to
15 Bystander CPR Early CPR Increases Survival
16
17 Adult BLS and CPR Quality n Minimizing interruptions with a goal of chest compression fraction of at least 60% n CCF = It is the percentage of time in which chest compressions are done by rescuers during a cardiac arrest n Fewer pauses in CPR increase the chances of surviving a cardiac arrest (less than 10 sec)
18 Ventilation During CPR with an Advanced Airway n It would be reasonable to deliver 1 breath every 6 sec (10 breath/min)
19 ACLS Summary of Key Issues (New) n Vasopressin and Epinephrine n ETCO 2 for Prediction of Fail Resuscitation n Steroids (ICHA and OCHA) n B-Adrenergic Blocking Drugs n Lidocaine n PCI n ECMO n Targeted Temperature Management
20 Vasopressin and Epinephrine n Vasopressin was removed for simplicity n No benefit of vasopressin over epinephrine n Epinephrine - timing of administration l It is reasonable to administer as soon as possible after the onset of cardiac arrest due to an initial nonshockable rhythm (PEA/Asystole)
21 ETCO2 n Low ETCO2 (< 10 mmhg) in intubated pts after 20 mins of CPR is associated with a low likelihood of resuscitation (shouldn t be used in isolation)
22 Steroids n There are no data to recommend for or against the routine use alone for IHCA (Class IIb, LOE C-LD) n Uncertain benefit for OHCA
23 Post-Cardiac Arrest Drug Therapy: New n B-blocker l There is inadequate evidence to support routine use after cardiac arrest n Lidocaine l There is inadequate evidence to support the routine use after cardiac arrest
24 PCI n Should be performed emergently for OHCA pts with suspected cardiac etiology and STEMI (Class I, LOE B-NR) n Reasonable for select pts after OHCA with suspected cardiac etiology but w/o STE on ECG (Class II a, LOE B-NR) n Reasonable in post-cardiac arrest pts for whom angiography is indicated regardless of whether is comatose or awake (Class II a, LOE C-LD)
25 ECMO n May be considered for select pts, in settings where it can be rapidly implemented (Class IIb, LOE C-LD)
26 Targeted Temperature Management n All comatose pts with ROSC should have a TTM for at least 24 hrs l TT between 32ºC-36ºC, maintained constantly n Continuing TM beyond 24 hrs l Is reasonable in comatose pts to actively prevent fever n Out of Hospital Cooling l Not recommended Nielsen N. et al, N Engl J Med. 2013;369:
27 PROGNOSTICATION for poor outcome USING CLINICAL EXAM n The earliest time for prognostication in pts treated with TTM, may be 72 hrs after return of normothermia (Class II b, LOE C-EO) n The earliest time for prognostication in pts not treated with TTM is 72 hrs after cardiac arrest (Class I, LOE B-NR)
28 Updated Recommendations: Special Circumstances n Naloxone administration in combination with BLS care for opioid-associated life-threatening emergencies n Intravenous lipid emulsion considered for treatment of local anesthetic systemic toxicity n Refined recommendations regarding uterine displacement for CPR during pregnancy
29 Take-Home Messages n Lay provider care saves lives n Defibrillation as early as possible n Medications have modest benefit n Advanced Airway is a lower priority early in cardiogenic arrest l If performed, don t interrupt more important interventions (compressions, defibrillation)
30 Take-Home Messages n Post-resuscitation care is a key component of management l l Targeted Temperature Management Coronary Reperfusion n Do not forget your basic critical care skills
31
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