Ultimate Metabolic and Calorie Burning Makeover By Len Kravitz, Ph.D., Recommended Readings: Kravitz, L.

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1 Ultimate Metabolic and Calorie Burning Makeover By Len Kravitz, Ph.D., Recommended Readings: Kravitz, L. (2009). Calorie burning: It's time to think "outside the box:". IDEA Fitness Journal, 6(4), Kravitz, L. (2009). Too much sitting is hazardous to your health. IDEA Fitness Journal, 6(9), Kravitz, L. (2006). A NEAT "new" strategy for weight control. IDEA Fitness Journal, 3(4), I. Donnelly, J.E. (2009). Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Medicine & Science in Sports & Exercise, 41(2), A. A little weight loss is a big health gain! Weight loss of as little as 3% to 5% of initial body wt. equals improved HDL-C, better glucose metabolism, decrease in triglycerides, and lowered CVD risk B. Weight maintenance is now defined as a change of <3% in body weight C. Clinical weight gain is defined as >5%; clinical means involving some type of medical treatment, observation or diagnosis D. Weight maintenance exercise guidelines; moderately vigorous physical activity min/week (which is kcals/week; which is miles/week or km/wk). Sufficient in preventing weight gain greater than 3% E. For clinical weight loss >5% body weight (physical activity only): <150 minutes has very little effect; minutes/week (range) shows greatest effect (5 to 7.5 kg over time) F. Weight regain is biggest challenge. Consistent physical activity is the BEST predictor of sustained weight management after weight loss. G. People who lost >10% of initial body weight in 24 months are doing 275 min of physical activity/week I. Resistance training framework: resistance training increases muscle mass, which increases RMR, which increases total energy expenditure, which decreases body fat J. Take Home: Weight loss and prevention of weight regain goal; minutes exercise/week II. Katzmarzyk, P.T. et al. (2009). Sitting time and mortality from all causes, cardiovascular disease, and cancer. Medicine & Science in Sports & Exercise, 41(5), A. Too much sitting is hazardous to health B. New science of sedentary behavior or inactivity physiology C. Not the endpoint of physical activity continuum D. Adults/children spend 70% of waking day working at a desk, riding in a car, eating a meal, playing video games, working on a computer, watching TV E. Canadian Fitness Survey: Mortality over 12-year period, 7,278 men and 9,735 women; yrs. F. Leading causes of mortality: cardiovascular disease (CVD), cancer, respiratory diseases, injuries, nervous system disorders, accidents, and other G. Major finding: Strong association between sitting and mortality; Mechanism: sitting results in dramatic drops in lipoprotein lipase (captures fat from blood for fuel); leads to soaring levels of triglycerides; Too much sitting also results in lowered levels of HDL-C and elevates risk to CVD H. Move a Little, Lose a Lot by James A. Levine, M.D., Ph.D. I. Research on NEAT (Non-Exercise Activity Thermogenesis): Fidgeters expend 352 additional kcals/day (16 kg/year) J. Action plan to combat sedentary behavior: create a metabolic profile for client: to do this track everything a client does from wake-up time to sleep time (time everything out)

2 K. Case study: Interventions at work to combat sedentary lifestyle: 1) stand up and walk around the office every 30 minutes, 2) stand up and move every time the client needs to get some water, 3) walk to the farthest bathroom in the worksite facility, 4) take a walk break with every coffee break, 5) consider walking around the room when talking on the phone L. Case study: Interventions at home to combat sedentary lifestyle: 1) get up and move during every commercial, 2) stand up and move for the opening segment of each TV show, 3) at the end of reading 4,6 or 8 pages, get up and walk around the room or house M. Source for ideas for moving: smallstep.gov (walk to work, walk during your lunch hr, walk instead of drive whenever you can, take a family walk after dinner, skate to work instead of drive, mow the lawn with a push mower, walk to your place of worship instead of driving, walk your dog, replace Sunday drive with a Sunday walk, park safely in the back of the parking lot, work and walk around the house, take your dog to the park, wash the car by hand, run or walk fast when doing errands, pace the sidelines at your kid s games, walk the airport while awaiting your flight, walk to a coworkers desk instead of ing or calling, make time in your day for moving, bike with family and friends, if you find it difficult to be active after work, try it before work, take a walk break with a coffee break, perform gardening and/or home repairs, avoid sitting for more than 30 min at a time, move around more at the grocery market, play with your kids 30 minutes a day, dance to music, walk briskly in the mall, take the long way to the water cooler, take the stairs instead of the escalator, go for a hike III. Herrera, L. & Kravitz, l. (2009). Yes! You do burn fat during resistance exercise. IDEA Fitness J, 6(4), A. Researched fat burning during and immediately following resistance training B. Ormsbee, M.J. (2007). Fat metabolism and acute resistance exercise in trained men. Journal of Applied Physiology, 102, C. Looked at 8 trained (3 days/week for the last 2 years) males (24 years of age) D. Assessed 10-RM on chest press, lat pull down, shoulder press, leg press, leg extension, and leg curl E. Exp. trial: 3 sets of 10 reps using a load of % of 10-RM of exercises; 90-second rest between sets F. Microdialysis: measure glycerol (index of lipolysis) in abdominal tissue G. Indirect calorimetry: Fat and carbohydrate (CHO) use; RER respiratory exchange ratio during and after the workout; control trial of no exercise on a different day H. Results of kcal expenditure; elevated 10.5% after the workout I. Results of microdialysis; glycerol levels elevated 78% during and 75% after the resistance training workout as compared to the control trial J. Results of RER (fat oxidation): Fat oxidation was 105% higher compared to control trial K. Why is fat oxidation elevated after resistance training? Elevated epinephrine and norepinephrine L. Important point: This fat oxidation effect has only been shown true with trained individuals IV. Let s talk about the calorie A. The most common term used to express energy expenditure B. Defined as the heat energy required to raise the temperature of 1 gram of water 1 degree Celsius C. Kilocalorie heat energy required to raise 1 kilogram of water 1 degree Celsius D. Why are we interested in energy expenditure? To determine the work being accomplished during exercise E. The key is understanding energy expenditure F. Ergometry (the measurement of work): Ergometer (Ergo=work, meter=measure) G. Work=Force x Distance: What are we expressing with work? Energy H. What mode burns the most amount of calories? What is the BEST aerobic mode? I. How does the 1 st Law of Thermodynamics relate to all of this? Energy just changes form.

3 J. Overview of energies being used in exercise: mechanical energy, heat energy, chemical energy K. What is calorimetry: the measurement of heat energy: Example of 1 st Law of Thermodynamics L. Why do fats yield more kcals/gram? Into the mitochondrion. Answer=it is all about the hydrogens M. Why does the body prefer carbohydrate for fuel during exercise? Fat breakdowns 30-40% slower V. How does the body regulate fat metabolism and lipolysis? A. Principal hormones and enzymes of fat metabolism B. Catecholamines: epinephrine and norepinephrine (fight or flight hormones), major hormones of lipolysis in adipose and intramuscular tissue (at rest and exercise) C. Site of activation of epinephrine and norepinephrine: (alpha-adrenergic which inhibit lipolysis) and (betaadrenergic which stimulate lipolysis) D. Insulin: strongest inhibitor of lipolysis either before or during exercise. During endurance exercise when the need for fat is high, insulin levels are typically lower. E. Growth hormone: stimulatory effect on lipolysis and fat metabolism during exercise and recovery F. Thyroid stimulating hormone and thyroxine: increase fat metabolism G. Lipolytic enzymes: Hormone sensitive lipase (HSL) 1. Hydrolysis of fat 2. Catecholamines stimulate HSL 3. Insulin inhibits HSL H. Lipolytic enzymes: Lipoprotein lipase (LPL) 1. Promotes storage of fat 2. Insulin stimulates LPL I. Effect of exercise on lipolysis J. Mild to moderate exercise (25-65% of VO 2 max) increases lipolysis 5 to 10 fold K. Moderate intensity exercise doubles adipose tissue blood flow with a >10 fold increase in skeletal muscle L. During exercise where are we getting the fat we use? 25% to >50% is intramuscular fat with the rest from fatty acids in the blood and then adipose tissue M. Major way exercise improves fat metabolism: increase in mitochondrion number (15%) and size (35%) Len s Favorite Calorie Burning Programs from Scientific Studies 1) TRACK (OR TREADMILL) HITT Warm-up: Light 10min run Interval: 800meter runs at approximately 90% of maximal heart rate on 6-20 ratings of perceived exertion scale (RPE scale) which is Hard to Very Hard Each 800meter interval should be timed Rest Interval: Light jog or walk for same amount of time it took to run each 800meter Work/Rest ratio: 1-to-1 ratio. The time for the interval (800meter) and rest interval should be the same Frequency: Try to complete 4 repetitions Modify: The distance of the interval can be adjusted from 200meter to 1000meter. Vary length of the rest interval. Adapted from Musa, D.I., et al. (2009). The effect of a high-intensity interval training program on high-density lipoprotein cholesterol in young men. Journal of Strength and Conditioning Research, 23(2), ) HILL TRAINING HITT Warm-up: 10min of light jogging Interval: Set treadmill incline at 5%-8% grade and speed at 3 mph. During each interval increase speed to 5 mph 6.5 mph, while keeping grade at 5%. The length of the interval should be 1min. Rest Interval: Self-selected speed. Do not adjust incline. Work/Rest Ratio: 1-to-2 ratio. The work interval is 1min and the rest interval is 2min Frequency: 3-6 intervals

4 Cool Down: 5 10min of easy jogging Comments: This is a hill running interval session. Modify incline, running speed, interval length, and rest interval. Adapted from Seiler, S., and Hetlelid, K.J. (2005). The impact of rest duration on work intensity and RPE during interval training. Medicine & Science in Sports & Exercise, 37(9), ) COMBINATION HITT AND CV CONDITIONING Warm-up: 10min of light exercise Interval: 30seconds of sprinting (any mode) Rest Interval: 30second rest Work/Rest Ratio: 1-to-1 ratio. The work interval is 30seconds and the rest interval is 30seconds Frequency: Preformed continuously for 20-30min Note: After completion of interval session perform a 20-30min slow jog or walk at 50% HRmax Modify: Complete on multiple modes (cycling, elliptical training, running, rowing, stair stepping, etc.) Adapted from Seiler, S., and Hetlelid, K.J. (2005). The impact of rest duration on work intensity and RPE during interval training. Medicine & Science in Sports & Exercise, 37(9), ) STEP-WISE INTERVAL TRAINING Protocol: Start at a relatively easy workload (cardiovascular warm-up) for 5min of exercise and then increase intensity about percent. At the end of each subsequent 4min exercise stage increase the work load about percent for the first 4min training period. This program can be halted when a particular intensity level is reached or a specific duration is attained. Try completing step-wise UP and step-wise DOWN sequence. Intensity: The initial work intensity should be about an RPE of 11. Then, depending on the means of increasing the intensity on the mode (i.e., speed, grade, stride, etc) increase the intensity roughly 1 RPE with each subsequent 4min stage (i.e., program starts at an RPE of 11; after 4min the intensity becomes a 12; after 4min the intensity becomes a 13; after 4min and intensity becomes a 14. Do until a specific time/intensity is attained. Duration: Duration should follow ACSM (2006) guidelines, which recommend 20-60min Adapted from Jacobs and Sjodin (1985). Relationship of ergometer-specific VO 2 max and muscle enzymes to blood lactate during submaximal exercise. British Journal of Sports Medicine, 19, ) CONTINUOUS INTERVAL TRAINING Warm-up 5-10min of light exercise 4-8 continuous endurance intervals Each interval is 4min followed by a 4min low-intensity rest (12min/mile) Each successive interval is at a faster pace: Let s look at an example 1) 10min/mile 2) 9:30min/mile 3) 9:00min/mile 4) 8:30min/mile 5) 8:00min/mile Complete on multiple modes Adapted from Akubat, I. et al. (2011) Intermittent exercise alters the heart rate-blood lactate relationship used for calculating the training impulse (TRIMP) in team sport players. Journal of Science and Medicine in Sport / Sports Medicine Australia,14(3), ) METABOLIC BASE TRAINING Warm-up: 5-10min Protocol: Perform continuous submaximal aerobic exercise on the selected mode Intensity: Intensity is 65% of VO 2 peak which would be about a 14 RPE (Somewhat Hard) Duration: Duration is 40-60min of sustained cardiorespiratory exercise Called metabolic base training because it increases mitochondrial density Adapted from Burgomaster, K. et al. (2008). Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans. Journal of Applied Physiology, 586(1), ) MAXIMAL LACTATE THRESHOLD TRAINING Warm-up: 5-10min of light-to-moderate intensity exercise Protocol: Continuous aerobic exercise at 70-85% VO 2 max (14-17 RPE or Somewhat Hard to Hard) Duration: 30-60min on any mode: Also referred to as Maximal Steady State Training Adapted from Smith, J. and McNaughton, L. (1993). The effects of intensity on excess post-exercise oxygen consumption and energy expenditure of moderately trained men and women. European Journal of Applied Physiology, 67,

5 8) CONTINUOUS CV TRAINING WITH TWO BIG EFFORTS Warm-up:10min of light exercise Workout: A low to moderate intensity 30-50min continuous run at 60% - 70% heart rate max. At any time during the workout (beginning, middle or end) perform two Maximal Speed Efforts lasting 2min. Modify: Complete on multiple modes Adapted from Smith et al. (2003).Optimising high-intensity treadmill training using the running speed at maximal O 2 uptake and the time for which this can be maintained. European Journal of Applied Physiology, 89(3-4), v ) THE THREE 1-MILE WORKOUT Warm-up: 5min of light jogging Workout: Workout is three 1-mile bouts with a 5-minute active rest between each mile. The first mile should be at fast pace (record time). The second mile should be at slower pace and intensity than the first mile. The goal of the final mile is to complete it in the same time as the first mile. Interval: one-mile Rest Interval: 5min of low intensity running between mile bouts Modify: Any mode of exercise can be substituted for running Babineau et al. (1997). Physiological response of 5/1 intermittent aerobic exercise and its relationship to 5km endurance performance. International Journal of Sports Medicine,18(1), End