The Projects of Scientific Grant Agency of the Ministry of Education of Slovak republic and the Slovak Academy of Sciences

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1 The Projects of Scientific Grant Agency of the Ministry of Education of Slovak republic and the Slovak Academy of Sciences The list of actual projects at Jessenius Faculty of Medicine Comenius University in Martin: 1. The principal investigator: Assoc. Prof. Michal Javorka, M.D., PhD. Number of the project: 1/0059/13 Title of the project: Cardiovascular dysregulation in adolescents with overweight and obesity: complex assessment by analysis of heart rate variability, blood pressure variability and their synchronization. Duration of the project: The principal investigator: Radovan Murín, Mgr., PhD. Number of the project: 1/0242/13 Title of the project: Metabolism of homocysteine by human neural cells. Duration of the project: The principal investigator: Assoc. Prof. Miriam Čiljaková, M.D., PhD. Clinic of Pediatrics and Adolescent Medicine Number of the project: 1/0262/14 Title of the project: The changes in sleep architecture and its influence on current and l long-term control of type 1 diabetes mellitus in childhood. Duration of the project: The principal investigator: Assoc. Prof. Soňa Fraňová, Dr., PhD. Number of the project: 1/0165/14 Title of the project: Pharmacological modulation of ciliary beat frequency in respiratory epithelium. Duration of the project: The principal investigator: Prof. Peter Kaplán, Dr., PhD. Number of the project: 1/0129/14 Title of the project: Effect of aging and ischemia on structural and functional properties of proteins. 6. The principal investigator: Prof. Ján Švihra, M.D., PhD. Clinic of Urology Number of the project: 1/0067/14 Title of the project: Mechanisms of neurogenic lower urinary tract dysfunction - basic and clinical studies. 1

2 7. The principal investigator: Assoc. Prof. Jana Plevková, M.D., PhD. Number of the project: 1/0107/14 Title of the project: Antagonists of H3 and H4 histamine receptors antitussive efficacy in the upper airway cough syndrom studies in guinea pig models. 8. The principal investigator: Assoc. Prof. Juraj Mokrý, M.D., PhD. Number of the project: 1/0260/14 Title of the project: Influence of phosphodiesterase inhibitors on apoptosis and inflammation in experimentally induced allergic airways inflammation. 9. The principal investigator: Assoc. Prof. Daniela Mokrá, M.D., PhD. Number of the project: 1/0305/14 Title of the project: New strategies in the treatment of acute lung injury. 10. The principal investigator: Assoc. Prof. Miloš Jeseňák, M.D., PhD. Clinic of Pediatrics and Adolescent Medicine Number of the project: 1/0252/14 Title of the project: Study of immune tolerance mechanisms in relationship with the development of bronchial asthma in children. 11. The principal investigator: Assoc. Prof. Ingrid Tonhajzerová, M.D., PhD. Number of the project: 1/0087/14 Title of the project: Altered response to stress a potential pathomechanism of cardiovascular complications of the civilization diseases. 12. The principal investigator: Prof. Lukáš Plank, M.D., PhD. Department of Pathological Anatomy Number of the project: 1/0268/15 Title of the project: Analysis of immunohistochemical p53 protein expression in trephine bone marrow biopsies as a contribution for prediction of therapeutical effects in patients with high risk myelodysplastic syndrome. Duration of the project: The principal investigator: Mária Kovalská, Dr., PhD. Department of Histology and Embryology Number of the project: 1/0229/15 Title of the project: Association of induced hyperhomocysteinemia with progression of neurodegenerative changes under the experimental conditions. 2

3 14. The principal investigator: Prof. Mirko Zibolen, M.D., PhD. Clinic of Neonatology Number of the project: 1/0100/15 Title of the project: Genetic heterogeneity in retinopathy of prematurity. 15. The principal investigator: Assoc. Prof. Zora Lasabová, Dr., PhD. Department of Molecular Biology Number of the project: 1/0102/15 Title of the project: Free circulating mirnas and mirna-related single nucleotide polymorphism in the pathogenesis of preeclampsia as candidates for non-invasive biomarkers. 16. The principal investigator: Prof. Miloš Tatár, M.D., PhD. Number of the project: 1/0226/15 Title of the project: The role of vagus nerves in visceral pain. 17. The principal investigator: Assoc. Prof. Mariana Brozmanová, Dr., PhD. Number of the project: 1/0070/15 Title of the project: Immunological mechanisms of neural hypersensitivity in eosinophilic disorders of gastrointestinal system. Duration of the project: The principal investigator: Michal Šimera, Dr., PhD. Department of Medical Biophysics Number of the project: 1/0253/15 Title of the project: Interations of neuronal structures controlling respiratory and cardiomotor functions in anaesthetized animals. Duration of the project: The principal investigator: Prof. Kamil Javorka, M.D., D.Sc. Number of the project: 1/0202/16 Title of the project: Mechanisms of the cardiovascular system regulation in newborns by autonomic nervous system. 20. The principal investigator: Prof. Andrea Čalkovská, M.D., D.Sc. Number of the project: 1/0469/16 Title of the project: Pulmonary surfactant and lipopolysaccharide: interaction and its functional consequences. 21. The principal investigator: Prof. Marián Mokáň, M.D., D.Sc., FRCP Edin Clinic of Internal Medicine I. 3

4 Number of the project: 1/0160/16 Title of the project: Diagnostic - prognostic relevance of adipocytokine network and glucose homeostasis assessment in cachexia. 22. The principal investigator: Ema Kantorová, M.D., PhD. Clinic of Neurology Number of the project: 1/0287/16 Title of the project: Correlation of MR volumetry and MR spectroscopy of subcortical gray matter with electrophysiological measures and selected laboratory markers in patients during early stages of multiple sclerosis, with a focus in highly active forms of the disorder. 23. The principal investigator: Assoc. Prof. Martina Šutovská, M.D., PhD. Number of the project: 1/0163/16 Title of the project: The role of cytokines, chemokines and growth factor in pathogenesis of degenerative spine disorders. 24. The principal investigator: Assoc. Prof. Peter Kubatka, Dr., PhD. Department of Medical Biology Number of the project: 1/0108/16 Title of the project: The evaluation of anti-tumor effects of plant-derived functional foods in the breast cancer model. 25. The principal investigator: Prof. Ján Staško, M.D., PhD. Clinic of Hematology and Transfusiology Number of the project: 1/0168/16 Title of the project: The use of monitoring of changes in haemostasis and detection of microrna in the prediction of pregnancy complications in women with high-risk pregnancies. 26. The principal investigator: Prof. Ján Lehotský, Dr., D.Sc. Number of the project: 1/0128/16 Title of the project: Epigenetic and molecular mechanisms of neuroprotection and ischemic tolerance. 27. The principal investigator: Prof. Marián Adamkov, M.D., PhD. Department of Histology and Embryology Number of the project: 1/0129/16 Title of the project: Mismatch repair proteins (MMRP) and survivin in pathogenesis of colorectal cancer. 4

5 28. The principal investigator: Assoc. Prof. Ivan Poliaček, Dr., PhD. Department of Medical Biophysics Number of the project: 1/0072/16 Title of the project: CENTRAL NEUROCHEMICAL MODULATION OF AIRWAY DEFENSIVE MECHANISMS. 5

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