Imagine The Possibilities Of Clearer Skin

Transcription

1 For Moderate Or Severe Plaque Psoriasis CONSIDERING OR STARTING STELARA? Imagine The Possibilities Of Clearer Skin STELARA is a prescription medicine approved to treat adults 18 years and older with moderate or severe plaque psoriasis that involves large areas or many areas of their body, who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills). other risks for STELARA. Discuss any questions you have with your doctor.

2 Discover STELARA STELARA is a prescription medicine used to treat moderate or severe plaque psoriasis. Whether you re starting STELARA or considering treatment, use this brochure to learn about how STELARA works, how often to take STELARA, information about plaque psoriasis, and other resources. When you find the right treatment, you can start imagining the possibilities of clearer skin. STELARA Can Help Provide Clearer Skin STELARA is a proven plaque psoriasis treatment that may help provide clearer skin and reduce symptoms of plaque thickness, scaling, and redness. In a medical study: 7 out of 10 people taking STELARA saw at least 75% clearer skin at 12 weeks 6 out of 10 people had their plaque psoriasis rated as cleared or minimal at 12 weeks Nearly 8 out of 10 people who initially saw at least 75% clearer skin with STELARA maintained their results with continued therapy at 2 years* Example of moderate to severe plaque psoriasis Example of 75% skin clearance Individual results may vary. * Includes only people who responded at 7 and 10 months. They were allowed to use topical medicines along with STELARA after nearly one and a half years. For illustrative purposes only. Individual results may vary. 2

3 How STELARA Works STELARA targets an underlying cause of plaque psoriasis an overactive immune system. It blocks two proteins called IL-12 and IL-23 that may play a role in plaque psoriasis. This may slow down how fast skin cells are made and may reduce inflammation. Convenient Dosing Schedule 4 Doses A Year After 2 Starter Doses STELARA provides a convenient dosing schedule of 4 times a year after 2 starter doses. That gives you a full 12 weeks between treatments to spend time doing what matters to you. STELARA is a 45 mg or 90 mg injection given under the skin as directed by your doctor at weeks 0, 4, and every 12 weeks thereafter. It is administered by a healthcare provider or self-injected only after proper training. Your healthcare provider will check your symptoms at all your scheduled appointments while continually reviewing your response to treatment. Week 0 Week 4 12 weeks 12 weeks 12 weeks 12 weeks Ask your doctor if STELARA may be right for you. 1st Starter Dose 2nd Starter Dose Maintenance Dose Maintenance Dose Maintenance Dose Maintenance Dose Visit STELARAinfo.com to learn more about how STELARA works. The quarterly maintenance dosing for STELARA really works well. I know that with my provider, we can definitely have a good schedule. Pamela 3

4 Getting Started With STELARA Ask About Your Insurance Benefits Figuring out your insurance benefits can be tricky, but that doesn t mean you should miss out on the opportunity to find the right treatment. Important STELARA can be covered in 2 ways: through your pharmacy and/or medical benefits. If your doctor s staff or pharmacy says that you re not covered, make sure to ask them if they ve checked both benefits. Don t assume that the medical benefit has been investigated. Now that you and your doctor have decided on STELARA, your doctor s staff is going to initiate the benefits investigation process to determine your medication costs. We also have StelaraSupport Case Coordinators who can help you verify and understand your insurance benefits and explain your potential out-of-pocket medication costs for STELARA. If you have private insurance, you may also qualify for our Instant Savings Program, a co-pay assistance program that may help lower your out-ofpocket medication expenses to $5 per dose.* For more information about the program and to understand the eligibility requirements, please ask about our Instant Savings brochure. *$20,000 maximum program benefit per calendar year. Not valid for patients enrolled in Medicare, Medicare Part D, or Medicaid. Eligibility requirements and restrictions apply. If you do not have private insurance, call StelaraSupport to help you understand other financial assistance programs available to you. To learn more about our Instant Savings Program and to activate your co-pay card, call STELARA ( ) 4

5 Get The Resources You Need When you get started on STELARA, you have access to a variety of free services to help you get the most out of your treatment and stay on track. Our dedicated team of StelaraSupport Case Coordinators is happy to answer your questions about a range of topics, including: A Step-By-Step Guide to GettiNG StARted WitH SteLARA Get Started Right Read the Step-By-Step Guide To Getting Started With STELARA located in your Welcome Kit. Janssen Nurse Support: Nurses are available weekdays, 9 am to 8 pm, and weekends, 9 am to 5 pm ET. At all other times, a nurse will return your call in about 15 minutes. Call STELARA ( ). Self-Injection Support: If you and your doctor decide you will selfinject, StelaraSupport can help you with a how-to video, syringe disposal information, and a Safe Returns program when you call a Care Coordinator or visit us at StelaraInjectionSupport.com. If your doctor decides that you or a caregiver may give injections at home, you should receive training on the right way to prepare and inject STELARA. Do not try to inject yourself until you or your caregiver has been properly trained by a healthcare professional. To take advantage of these resources, call a StelaraSupport Case Coordinator at STELARA ( ) or visit us online. 5

6 Enroll In Additional Support Make sure you get the most out of your treatment by enrolling in StelaraSupport a customized program for people who are taking STELARA. When you enroll in the program, you will gain access to the following tools and resources: Healthy Living Guide For wellness tips, download your FREE digital guide, Your Journey To Healthier Living. It s full of useful information including: Tips on nutrition Healthy and delicious recipes Exercise and stress relief information Support s Get s to help you stay on track with your treatment as well as great tips on diet, exercise, and stress relief. Medication Reminders To help you stay on track with your upcoming dose of STELARA, StelaraSupport can send you timely reminders by phone, text, or before your next dose is due. Manage All Your Medications With Our Free App Get medication reminders and a dose of encouragement in the palm of your hand with Care4Today Mobile Health Manager. Download the free app today. Visit mhm.care4today.com. To gain access to these helpful support tools, enroll in StelaraSupport by visiting JoinStelaraSupport.com or by calling STELARA ( ). 6

7 Learn About Plaque Psoriasis Causes Although the exact cause of plaque psoriasis is unknown, it is understood that the immune system, environmental factors, and family history can play a role. The immune system speeds up, which causes inflammation and a large number of skin cells to grow. Instead of falling off (shedding), the cells pile up on the surface of the skin, forming psoriatic plaques. Symptoms of plaque psoriasis include plaque thickness, scaling, and redness. Triggers Certain things may cause plaque psoriasis to flare. These include stress, skin injuries, strep infections, and certain medications. Weather can also trigger psoriatic symptoms, especially in cold and dry climates. During the winter, moisture leaves the skin because of the cold and dry air, which may worsen plaque psoriasis. Treatments Since plaque psoriasis is a chronic (lifelong) condition, it is important to work with your doctor and find a treatment that s right for you. Your doctor will prescribe a plaque psoriasis treatment for you based on many things, including the severity and location of your plaque psoriasis, your age, and your medical history. Therapies commonly used include: topical therapies, light therapies, systemic therapies, and biologics. I tried topicals that my physician had given me, and also some light therapy. I was very discouraged with my psoriasis, so I went back to my doctor and he suggested STELARA and I was completely on board. I was just super happy that he had something else that he could provide for me to try. Jill 7

8 Are You Also Experiencing Joint Symptoms? Along with your skin symptoms, if you are also experiencing pain, stiffness, and swelling in your joints, you may actually have a condition called psoriatic arthritis. In fact, 1 in 3 people diagnosed with plaque psoriasis also develop psoriatic arthritis. Both conditions are related to the immune system, but some people may have either the skin or joint symptoms first. Pain, swelling, stiffness, or tenderness in one or more joints Symptoms The severity and frequency of symptoms vary by person. Be sure to tell your doctor if you have any of these symptoms. Joints that are red or warm to the touch Sausage-like swelling in one or more of your fingers or toes Pain in and around the feet and ankles Thick, red patches on the skin that often have a silvery scale STELARA is a prescription medicine approved to treat adults 18 years and older with active psoriatic arthritis, either alone or with methotrexate. 8

9 Inspiring Story Of A Model With Plaque Psoriasis CariDee Experiences Clearer Skin From This Season... To The Next CariDee English, winner of America s Next Top Model, 2006,* has moderate to severe plaque psoriasis. But she never lets it slow her down. Working with her doctor to find a treatment that works for her lets CariDee follow her passions, while staying in season. CariDee has experienced clearer skin, and she s getting much-needed relief from her symptoms of plaque thickness, scaling, and redness. With 4 doses a year after 2 starter doses, she found a treatment schedule that works for her. Visit STELARAinfo.com for more patient stories and hear why STELARA is right for them. CariDee is representative of a person responding to treatment with STELARA under a doctor s care. Individual results may vary. CariDee is a paid spokesperson of Janssen Biotech, Inc. *America s Next Top Model courtesy of Pottle Productions, Inc. No endorsement implied. STELARA is a 45 mg or 90 mg injection given under the skin as directed by your doctor at weeks 0, 4, and every 12 weeks thereafter. It wasn t always clearer skin for CariDee. When her plaque psoriasis worsened, she decided to take charge by researching her condition and working with her doctor. She understands the importance of sharing even the tiniest details of her condition with her doctor, and together, they found a treatment that was right for her STELARA. With only 4 doses a year after 2 starter doses, STELARA helps me be in season. CariDee 9

10 Work With Your Doctor To Find The Right Treatment If you haven t already started STELARA, consider the questions below and use the Two-Minute Appointment Prep so you can have a more productive conversation with your dermatologist. Things To Ask Your Doctor Given my history, what treatment options may help provide relief from my symptoms of plaque thickness, scaling, and redness? Am I a candidate for a biologic treatment like STELARA? How do biologic medicines treat moderate or severe plaque psoriasis? How does STELARA work to treat plaque psoriasis? What are the important safety considerations for STELARA? Things To Ask Yourself Do you feel that your current treatment is helping your symptoms enough? Have you had a thorough discussion with your doctor about your symptoms and your response to treatment? Have you ever experienced joint symptoms? (If so, you may be at risk for developing psoriatic arthritis.) Have you explored all treatment options with your doctor recently? (If you have experienced joint symptoms) Am I at risk for developing psoriatic arthritis? 10

11 Two-Minute Appointment Prep Take charge and use this Doctor Discussion Guide to record your symptoms, take notes, and have a conversation with your doctor. Treatment History I have tried the following psoriasis medications so far (check all that apply): o Topicals o Phototherapy/PUVA o Oral Medications Injections/Infusions: o Enbrel * (etanercept) o Raptiva * (efalizumab) o Other Injection/Infusion o Amevive * (alefacept) o Humira * (adalimumab) * Indicated trademarks are registered trademarks of their respective owners. Record Your Symptoms Circle or color in all the areas of your body affected by skin or joint symptoms since your last visit. You should also include any flare-ups that you have had in between visits. This will help your doctor get a clearer picture of your condition. Think about all your symptoms, including plaque thickness, scaling, and redness, as well as any joint pain, stiffness, and swelling. Feel free to write down notes and share them with your doctor. Front Back If I could, I would change the following aspects about the treatments I ve tried (check all that apply): o Convenience of treatment o Control over flare-ups o Effectiveness of treatment o Frequency of flare-ups o Frequency of treatment o Time spent on treatment o Consistency of results o Number of treatments over time used at one time My symptoms such as plaque thickness, scaling, and redness have changed with my current treatment in the following way: gotten worse stayed the same gotten better I have also experienced pain, stiffness, and swelling in my joints (these symptoms may be attributed to psoriatic arthritis): o Yes o No Notes for my next appointment: This is how satisfied I am with my current treatment: not satisfied very satisfied Why I chose my answer: 11

12 IMPORTANT SAFETY INFORMATION STELARA (ustekinumab) is a prescription medicine that affects your immune system. STELARA can increase your chance of having serious side effects including: Serious Infections STELARA may lower your ability to fight infections and may increase your risk of infections. While taking STELARA, some people have serious infections, which may require hospitalization, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses. Your doctor should check you for TB before starting STELARA and watch you closely for signs and symptoms of TB during treatment with STELARA. If your doctor feels that you are at risk for TB, you may be treated for TB before and during treatment with STELARA. You should not start taking STELARA if you have any kind of infection unless your doctor says it is okay. Before starting STELARA, tell your doctor if you think you have an infection or have symptoms of an infection such as: fever, sweats, or chills muscle aches cough shortness of breath blood in your phlegm weight loss warm, red, or painful skin or sores on your body diarrhea or stomach pain burning when you urinate or urinate more often than normal feel very tired are being treated for an infection get a lot of infections or have infections that keep coming back have TB, or have been in close contact with someone who has TB After starting STELARA, call your doctor right away if you have any symptoms of an infection (see above). STELARA can make you more likely to get infections or make an infection that you have worse. People who have a genetic problem where the body does not make any of the proteins interleukin 12 (IL-12) and interleukin 23 (IL-23) are at a higher risk for certain serious infections that can spread throughout the body and cause death. It is not known if people who take STELARA will get any of these infections because of the effects of STELARA on these proteins. Cancers STELARA may decrease the activity of your immune system and increase your risk for certain types of cancer. Tell your doctor if you have ever had any type of cancer. Some people who had risk factors for skin cancer developed certain types of skin cancers while receiving STELARA. Tell your doctor if you have any new skin growths. Reversible posterior leukoencephalopathy syndrome (RPLS) RPLS is a rare condition that affects the brain and can cause death.the cause of RPLS is not known. If RPLS is found early and treated, most people recover.tell your doctor right away if you have any new or worsening medical problems including: headache, seizures, confusion, and vision problems. Serious Allergic Reactions Serious allergic reactions can occur. Get medical help right away if you have any symptoms such as: feeling faint, swelling of your face, eyelids, tongue, or throat, trouble breathing, throat or chest tightness, or skin rash. Continued on next page 12

13 Continued from previous page Before receiving STELARA, tell your doctor if you: have any of the conditions or symptoms listed above for serious infections, cancers, or RPLS ever had an allergic reaction to STELARA or any of its ingredients. Ask your doctor if you are not sure. are allergic to latex. The needle cover on the prefilled syringe contains latex. have recently received or are scheduled to receive an immunization (vaccine). People who take STELARA should not receive live vaccines. Tell your doctor if anyone in your house needs a vaccine. The viruses used in some types of vaccines can spread to people with a weakened immune system, and can cause serious problems. You should not receive the BCG vaccine during the one year before taking STELARA or one year after you stop taking STELARA. have any new or changing lesions within psoriasis areas or on normal skin are receiving or have received allergy shots, especially for serious allergic reactions receive or have received phototherapy for your psoriasis have any other medical conditions are pregnant or plan to become pregnant. It is not known if STELARA will harm your unborn baby. You and your doctor should decide if you will take STELARA. are breast-feeding or plan to breast-feed. It is thought that STELARA passes into your breast milk. You should not breast-feed while taking STELARA without first talking to your doctor. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine. When prescribed STELARA : Use STELARA exactly as prescribed by your doctor If your doctor decides that you or a caregiver may give your injections of STELARA at home, you should receive training on the right way to prepare and inject STELARA. Do not try to inject STELARA yourself until you or your caregiver has been shown how to inject STELARA by your doctor or nurse. Common side effects of STELARA include: upper respiratory infections, headache, tiredness, joint pain, and nausea. These are not all of the possible side effects with STELARA. Tell your doctor about any side effect that you experience. Ask your doctor or pharmacist for more information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call FDA Please read the full Prescribing Information, including the Medication Guide for STELARA, and discuss any questions you have with your doctor Janssen Biotech, Inc /