CURRICULUM VITAE. Key Qualifications: Internal Medicine Specialist and Medical oncologist. Name of Hospital: Firat Universitesi Hastanesi

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1 CURRICULUM VITAE Personal Details Surname: Elkiran First Name: Emin Tamer Akademic title/ position: Associate professor of Medicine Key Qualifications: Internal Medicine Specialist and Medical oncologist Research Interest: Solid and hematologic malignancies International Experience/Collaborations: Contact Details: Work Address: Name of Hospital: Firat Universitesi Hastanesi Street: Universite Mahallesi Town: Elazig Country:Turkey Post Code: Phone/Fax: /Ext: Date of Birth: Place and Country of Birth: Hekimhan-Malatya-Turkey Country of Citizenship: The Republic of Turkey Country of Training: Turkey First Language: Turkish Languages: English Akademic Details

2 Faculty/University ( name and address) Date of Graduation:1993 Ankara University Faculty of Medicine- Ankara-Turkey Postgraduate Training: ( Name and address of Center and Supervisor [s] in charge of Training) 1-Cukurova University Faculty of Medicine, Department of Internal Medicine-Adana-Turkey 2-Hacettepe University Faculty of Medicine, Department of Medical Oncology-Ankara- Turkey SUPERVISOR IN CHARGE OF TRAINING: From To Title of thesis: 1-Spontaneous ascite infection in cirrhotic patient, (Thesis of internal medicine) 2-Retrospective analysis of osteosarcoma patients, (Thesis of medical oncology) Accreditation: (Name, number and date of certificate issued by Universty, Medical Association or Government Body) Academic Experience: Cukurova University Faculty of Medicine, Department of Internal Medicine-Adana-Turkey 2-Hacettepe University Faculty of Medicine, Department of Medical Oncology Cukurova University Faculty of Medicine, Department of Internal Medicine Dec 1993-June 1998 Adana Karaisali Hospital June 1998-April 1999 Firat University Faculty of Medicine, Department of Internal Medicine April 1999-June 1999 Ankara University Faculty of Medicine, Department of Hematology June 1999-Augus 1999 Firat University Faculty of Medicine, Department of Internal Medicine Sep 1999-Oct 2001 Hacettepe University Faculty of Medicine, Department of Medical Oncology Oct Oct 2004 Firat University Faculty of Medicine, Department of Internal Medicine Since Oct 2004 Memberships: 1- Society of Medical Oncology 2-Anatolian Society of Medical Oncology

3 3-Turkish Society of Hematology 4-Turkish Oncology Group International Publications 1. Elkiran, E. T., K. Altundag, S. Aksoy, I. K. Onal and G. Tekuzman, Systemic anaphylactic reaction following intrathecal administration of methotrexate in adult patient with primary central nervous system lymphoma, Am. J. Hematol, 75, 265 (2004). 2. Altundag, K., E. T. Elkiran and O. Altundag, Vascular endothelial growth factor is associated with the efficacy of endocrine therapy in patients with advanced breast carcinoma, Cancer, 100, (2004). 3. Altundag, K., O. Altundag, E. T. Elkiran, M. Cengiz and Y. Ozisik, Addition of granulocyte-colony stimulating factor (G-CSF) to adjuvant treatment may increase survival in patients with operable breast cancer: interaction of G-CSF with dormant micrometastatic breast cancer cells, Med. Hypotheses, 63, (2004). 4. Babaoglu, M. O., O. Karadag, Y. Saikawa, K. Altundag, T. Elkiran, U. Yasar and A. Bozkurt, Hepatotoxicity due to a possible ınteraction between cytosine arabinoside and dipyridamole: a case report, Eur. J. Clin. Pharmacol, 60, (2004). 5. Ozcakar, L., O. Karadag, M. Isik, E. T. Elkiran, O, Dikbas and K, Altundag, Progressive ascending paraparesia in an acute lymphoblastic leukemia patient: masked but not fallacious, J. Exp. Clin. Cancer Res, 23, (2004). 6. Karadag, O., M. O. Babaoglu, K. Altundag, T. Elkiran, U. Yasar and A. Bozkurt, 5- Fluorouracil-induced coronary spasm: may inhibition of hyperpolarization factors produced by CYP2C enzymes be the cause?, Oncology, 66, (2004). 7. Elkiran, E. T., K. Altundag, Y. Beyazit, N. Guler and A. Kars, Fluorouracil-induced neurotoxicity presenting with generalized tonic-clonic seizure, Ann. Pharmacother, 38, 2171 (2004). 8. Karadag, O., K. Altundag, E. T. Elkiran, O. Dikbas, G. Gedikoglu and A. Kars, Anterior abdominal wall synovial sarcoma: a rare presentation, Am. J. Clin. Oncol, 28, (2005). 9. Kurt, M., I. K. Onal, T. Elkiran, B. Altun, K. Altundag and I. Gullu, Acute tumor lysis syndrome triggered by zoledronic acid in a patient with metastatic lung adenocarcinoma, Med. Oncol, 22, (2005). 10.Kurt, M. A. Shorbagi, K. Altundag, T. Elkiran, I. Gullu and E. Kansu, Possible association between budd-chiari syndrome and gemtuzumab ozogamicin treatment in a patient with refractory acute myelogenous leukemia, Am. J. Hematol, 80, (2005).

4 11. Elkiran, E. T., B. Aygen, A. Karaoglu and K. Altundag, Metastatic osteosarcoma to the brain in adult patient, J. Neurooncol, 76, 213 (2006). 12. Elkiran, T., H. Harputluoglu, U. Yasar, M. O. Babaoglu, A.K. Dincel, K. Altundag, Y. Ozisik, N. Guler and A. Bozkurt, Differential alteration of drug-metabolizing enzyme activities after cyclophosphamide/adriamycin administration in breast cancer patients, Methods Find. Exp. Clin. Pharmacol., 29, (2007). 13. Elkiran, E. T., H. Abali, S. Aksoy, K. Altundag, M. Erman, A. Kars, A. Turker, G. Tekuzman and Y. Ozisik, Thymic epithelial neoplasia: a study {Okumura, Ohta, et al /id}of 58 cases, Med. Onco., 24, (2007). 14. Elkiran, E. T., Mar, N., Aygen, B., Gursu, F., Karaoglu, A. and Koca, S. Serum paraoxonase and arylesterase activities in patients with lung cancer in a Turkish population BMC Cancer, 7, 48, (2007). 15. Aydin, S., Geckil, H., Karaoglu, A., and Elkiran, E. T. Ghrelin: a novel peptide with therapeutic effect in certain cancers? Med Hypotheses, 69, , (2007). 16. Ozcakar, L., Elkiran, T., Altundag, K., and Tayfur, O. A fortuitous episode of brachial plexopathy in a patient with metastatic breast cancer Surg Neurol, 69, (2008 ). Presentations at International Scientific Meetings 1. Çeliker, H., B. Elkıran, Đ. H. Behçecioğlu, A. Demir and E. T. Elkıran, Yeni tanı almış kronik böbrek yetmezliği hastalarında endoskopik bulgular, IVth Congress of Balkan cities association of nephrology, dialysis, transplantation and artificial organs. XVI. Ulusal Nefroloji, Hipertansiyon, Diyaliz ve Transplantasyon Kongresi, 217, Đzmir, Çeliker, H., B. Elkıran, E. T. Elkıran, Đ. H. Behçecioğlu and A. Demir, Kronik böbrek yetmezliği hastalarında hepatobiliyer değişiklikler, IVth Congress of Balkan cities association of nephrology, dialysis, transplantation and artificial organs. XVI. Ulusal Nefroloji, Hipertansiyon, Diyaliz ve Transplantasyon Kongresi, 218, Đzmir, Çeliker, H., B. Elkıran, N. Đlhan, A. Var and E. T. Elkıran, Hemodializ ve periton diyalizinin oksidatif stres parametrelerinin üzerine etkileri, IVth Congress of Balkan cities association of nephrology, dialysis, transplantation and artificial organs. XVI. Ulusal Nefroloji, Hipertansiyon, Diyaliz ve Transplantasyon Kongresi, Đzmir, Đlhan, N., A. Var, H. Çeliker, B. Elkıran and E. T. Elkıran, Hemodializ hastalarında oksidan ve antioksidan parametreler üzerine yaş ve cinsiyetin etkisi, IVth Congress of Balkan cities association of nephrology, dialysis, transplantation and artificial organs. XVI. Ulusal Nefroloji, Hipertansiyon, Diyaliz ve Transplantasyon Kongresi, 225, Đzmir, 1999.

5 5. Elkıran, B., H. Çeliker, E. T. Elkıran, A. Var and N. Đlhan, Hemodializ hastalarında oksidatif stres üzerine trimetazine in etkileri, IVth Congress of Balkan cities association of nephrology, dialysis, transplantation and artificial organs. XVI. Ulusal Nefroloji, Hipertansiyon, Diyaliz ve Transplantasyon Kongresi, 226, Đzmir, Çeliker, H., B. Elkıran, E. T. Elkıran and A. Đ. Günal, Üremik hastalarda depresyon, IVth Congress of Balkan cities association of nephrology, dialysis, transplantation and artificial organs. XVI. Ulusal Nefroloji, Hipertansiyon, Diyaliz ve Transplantasyon Kongresi, 272, Đzmir, Var, A., N. Đlhan, H. Çeliker, B. Elkıran and E. T. Elkıran, Değişik membran tiplerin oksidan-antioksidan sistem parametreleri üzerine etkileri, IVth Congress of Balkan cities association of nephrology, dialysis, transplantation and artificial organs. XVI. Ulusal Nefroloji, Hipertansiyon, Diyaliz ve Transplantasyon Kongresi, 276, Đzmir, Abali, H., A. Türker, B. Öksüzoglu, T. Elkiran, M. Erman, Y. Ozişik and A. Kars, Primitive neuroectodermal tumor and Ewings sarcoma: Experience in adults at a tertiary care hospital, 27 th ESMO Congress, Nice, France, Annals of Oncology, Vol. 13, , Elkiran, T., B. Oyan, Y. Koç, A. Kars, A. Türker, F. Tekin, Y. Cetinkaya, O. Uzun, M. Akova, S. Unal, G. Tekuzman and E. Kansu, Infection complications during nonmyeloablative allogenic transplantation, XVII th Meeting Of The International Society Of Hematology (European & African Divison), Graz, Austria, 60, Aksoy, S., H. Abali, S. Kiliçkap, O. Yavas, B. Oyan, E. T. Elkiran, T. Aras, O. Ugurlu, N. Güler and G. Tekuzman, Outcome of well differentiated thyroid cancer: Single institution results 2004 ASCO Annual Meeting Proceedings (Post-Meeting Edition), J. Clin. Oncology, Vol. 22, 5615, Aygen, B., E. T. Elkıran, A. Karaoğlu and N. Akpolat, An unusual tumor of the renal pelvis: primary mucinous adenocarcinoma. A case report, XXIII. World Congress of Pathology and Laboratory Medicine, Đstanbul-Turkey, 282, Elkiran, T., N. Akpolat and B. Aygen, Extraskeletal osteosarcoma of the gluteal region: Case Report, XXIII. World Congress of Pathology and Laboratory Medicine, Đstanbul- Turkey, 265, Elkiran, T., B. Aygen and H. Yekeler, A case of bone marrow necrosis as the etiology of severe pancytopenia XXIII. World Congress of Pathology and Laboratory Medicine, Đstanbul-Turkey, 224, Elkiran, E. T., S. Çelebi, B. Aygen, A. Karaoğlu and I. Özercan, Primary malignant melanoma of esophagogastric junction: A case report, XXIII. World Congress of Pathology and Laboratory Medicine, Đstanbul-Turkey, 203, Elkiran, E. T., B. Aygen and Özercan I, A rare case of primary squamous cell carcınoma of the breast in a young woman, XXIII. World Congress of Pathology and Laboratory Medicine, Đstanbul-Turkey, 142, 2005.

6 16. Elkıran, E. T. and B. Aygen, Simultaneous occurrence of Hodgkin Lymphoma and tuberculosis: A case report, XXX th World Congress of the International Society of Hematology Đstanbul, Turkish Journal of Haematology (Supplement), Vol. 22, 178, Elkıran, T. and B. Aygen, Dental Filling: Cause of eosinophilia, XXX th World Congress of the International Society of Hematology, Đstanbul, Turkish Journal of Haematology (Supplement), Vol. 22, 204, Elkiran, E. T., K. Altundag, M. O. Babaoglu, U. Yasar, Y. Ozisik, N. Guler, A. Kara Dincel, and A. Bozkurt, Differential alteration of drug metabolizing enzyme activities in vivo after cyclophosphamide / adriamycin administration in operable breast cancer patients 2005 ASCO Annual Meeting Proceedings, J. Clin. Oncology, Vol. 23, No. 16S, Elkiran, E. T., N. Mar, B. Aygen, Gursu F, Koca S and A. Karaoglu, Serum paraoxonase activity changes in patients with lung cancer, 31 st ESMO Congress, Đstanbul, Turkey, Annals of Oncology, Vol. 17, ix253, Elkiran, E. T., A, Türker, A. Kars, H. Harputluoglu, M. Erman, G. Gedikoglu and G. Tekuzman, Retrospektive evaluation of osteosarcomas of the extremity in adults, 31 st ESMO Congress, Đstanbul, Turkey, Annals of Oncology, Vol. 17, ix166, 2006.