Since marts 2006 marts 2011 member of the Policy Board for Danish Society for Magnetic Resonance

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1 Name Helle Juhl Simonsen Date of Birth Address: Functional Imaging Unit Diagnostic Department Glostrup University Hospital Nordre Ringvej Glostrup Denmark Telephone Qualifications: Cert. Biomedical Laboratory Scientist, 1982, Amager Hospital, Copenhagen Oct. 87 Aug. 06: Research MRT, Biomedical Laboratory Scientist Danish Research Centre for Magnetic Resonance Copenhagen University Hospital, Hvidovre Kettegårds Allé 30 DK-2650 Hvidovre Denmark Current Position: Research MRT, Biomedical Laboratory Scientist Functional Imaging Unit Diagnostic department Glostrup University Hospital Nordre Ringvej Glostrup Denmark (Aug. 06 present) Since marts 2006 marts 2011 member of the Policy Board for Danish Society for Magnetic Resonance April 2011 member of the Policy Board for Section for Magnetic Resonance Technologists May 2012 chair of the Global Relation Committee January 2012 Member of the ISMRM Nordic Chapter Policy Board

2 Publications: Abstracts: Time course of the ADC of NAA compared with extracellular NAA in focal ischemia in the rat S Rosenbaum, T.N. Sager, A. Stensgaard, S. Topp, H. Simonsen, O.B. Paulson Proc ISMRM (1997), 1255 MR sequences and hardware optimized for MR imaging of rat heart at 4.7T A. Stensgaard, S. Topp, H. Simonsen Proc ISMRM (1998), 798 Pathogenesis of corticospinal tract degenration in ALS patient by diffusion tensor imaging S. Rosenbaum, M. Karlsborg, M.R. Wiegell, H. Simonsen, O. Gredal Proc. ISMRM (2002), 0048 MR Imaging of Plastinated Tissue IJ Rowland, HJ Simonsen, M Møller Proc. ISMRM (2002), 1025 Development and Application of an MR Compatible Electroporation System: In vivo Comparison of Clamp and Needle Electrodes IJ Rowland, HJ Simonsen, N Broberg, A Stensgaard Proc. ISMRM (2003), 1206 Cluster Analysis of Multi-Dose Dynamic Contrast Enhanced MRI Studies of Tumours IJ Rowland, C Andrup Kristensen, L Vejby Søgaard, H Simonsen, E Rostrup, PE Kristjansen Proc. ISMRM (2003) The Production of Vascular Casts for Light Microscopic and MR Imaging Investigations IJ Rowland, L Vejby Søgaard, HJ Simonsen Proc. ISMRM (2003), 1405 Development of an MR Compatible in vivo Angiogenesis Assay C.D. Ley, L. Vejby Søgaard, H.J. Simonsen, P.E. Kristjansen, I.J. Rowland Proc. ISMRM (2004), 1970 In vivo MR Study of Muscle Damage Following an Electrotransfer Gene Delivery Protocol Ian Rowland and Helle Simonsen Proc. ISMRM (2004), 1746 Development of Experimental Meningitis in Rats Studied using MRI Ian Rowland, Christian Brandt, Helle Simonsen, Lise Vejby Søgaard, Christian Østergaard, Jens D. Lundgren and Olaf B. Paulson Proc. ISMRM (2004), 1448 Pathogenesis of Corticospinal tract degeneration in ALS patients by Diffusion Tensor Imaging H. Simonsen, S. Rosenbaum, M. Karlsborg, M.R. Wiegell, O. Gredal SMRT & BAMRR Thirteenth Aannual Meeting, Kyoto Convention Centre, Kyoto Japan (3rd place award in the category of Research Focus Proffered Paper) Proc SMRT (2004), si 251 MR imaging of the Matrigel angiogenesis assay C.Ley, L.Vejby Søgaard, H.Simonsen, P.Kristjansen, I.J.Rowland Proc ESMRMB (2004), 238

3 Evolution of inflammation and hydrocephalus in experimental meningitis studied using MRI C. Brandt, L.Vejby Søgaard, H.Simonsen, C.Østergaard, J.Lundgren, O.Paulson, I.J.Rowland Proc ESMRMB (2004), 238 Evolution of brain edema in experimental pneumococcal meningitis H. Simonsen, C. Brandt, L. Vejby Søgaard, C. Østergaard, J. D. Lundgren, O. B. Paulson I.J. Rowland. Proc SMRT (2005) Semi-quantitative Assessment of Inflammation in dmri Using Data-Mining Techniques. M. Liptrot, T. Dyrby, H.Simonsen, L.Vejby Søgaard, C. Brandt, I.J.Rowland. Proc. ISMRM (2005) DRCMR as an international Reader Centre H. Schmidt, H. Simonsen, A.Skimminge, A.Langkilde, J. Marstrand, O.B.Paulson, I. K. Andersen, L.Vejby Søgaard Proc SMRT (2006) The Impact of Hydrocephalus in Experimental Meningitis C. Brandt, H. J. Simonsen, L. Vejby Søgaard, O. B. Paulson, I. J. Rowland Proc. ISMRM (2006) Functional Magnetic Resonance Imaging in a patient with cerebral infection H.J. Simonsen, D. Fuglø, B.S. Møller, M. Lindhardt, K. Kallenbach, H.B.W. Larsson Proc SMRT (2008) Magnetic Resonance Imaging and Optical Coherence Tomography obtained in patients with acute Optic Neuritis H.J. Simonsen, K. Kallenbach, D. Fuglø, M. Lindhardt, B.S. Møller, B. Sander, M. Larsen, H.B.W. Larsson SMRT & BAMRR 18th Annual Meeting Hawai i Convention Center, Honolulu, Oahu, USA. (3rd place award in the category of Research Focus Proffered Paper.) Proc SMRT (2009), page 126. Magnetic Resonance safety procedure - a training program for research students H.J. Simonsen, M. LiIndhardt, B.S. Møller, H.B.W. Larsson, A.E.Hannsen SMRT & BAMRR 19th Annual Meeting Stockholmsmässan AB (Stockholm International Fairs), Stockholm (2010) Dynamic Contrast-Enhanced T1-Weighted Perfusion MRI differentiates Tumour Recurrence from Radiation Necrosis: Relative Cerebral Blood Volume Measurements and FDG-PET Validation Vibeke Andrée Larsen, Helle J Simonsen, Ian Law, Henrik BW Larsson, Adam E Hansen ISMRM 18th Scientific Meeting and Exhibition Stockholmsmässan AB (Stockholm International Fairs), Stockholm, Sweden. (2010) Dynamic Contrast-Enhanced T1-Weighted Perfusion in Clinical use H.J.Simonsen, V.A. Larsen, M. Lindhardt, B.S. Møller, H.B.W. Larsson, A.E. Hansen SMRT & BAMRR 20th Annual Meeting; Montréal, Québec, Canada (2011) 3rd Place Clinical Focus Poster Award Experience with 3T, 32-channel Head Coil and Multi Transmit in the diagnosis of Malignant Melanomas in the eye H.J.Simonsen, M. Lindhardt, B.S. Møller SMRT & BAMRR 21th Annual Meeting; Melbourne, Victoria, Australia (2012) 3rd Place Clinical Focus Poster Award Magnetic Resonance safety procedure - a training program for research students H.J. Simonsen, M. LiIndhardt, B.S. Møller, H.B.W. Larsson, A.E.Hannsen MR Safety in Practice: Now & In the Future, ISMRM workshop, Lund Sweeden (2012) Abnormal blood-brain barrier permeability in multiple sclerosis investigated by dynamic contrast enhanced MRI (oral presentation, received "Certificate of Merit" award) S.P. Cramer, H.J. Simonsen, J.B. Frederiksen, E. Rostrup, H.B.W. Larsson; Glostrup/DK ESMRMB 30st Annual Meeting Toulouse, France (2013)

4 Articles: Corticospinal tract degeneration and possible pathogenesis in ALS evaluated by MR diffusion tensor imaging. S. Rosenbaum, M. Karlsborg, M.R. Wiegell, H. Simonsen, H. B. W. Larsson, O. Gredal ALS and other motor neuron disorders 2004, 5, In vivo study of experimental pneumococcal meningitis using magnetic resonance imaging Christian T Brandt, Helle Simonsen, Matthew Liptrot, Lise V Sogaard, Jens D. Lundgren, Christian Ostergaard, Niels Frimodt-Moller and Ian J Rowland BMC Medical Imaging 2008, 8:1doi Retinal nerve fiber layer thickness is associated with lesion length in acute optic neuritis K. Kallenbach, H. Simonsen, B. Sander, B. Wanscher, H. Larsson, M. Larsen, J.L. Frederiksen Neurology 2010;74: Retinal atrophy correlates with fmri response in patients with recovered optic neuritis D. Fuglø, K. Kallenbach, A. Tsakiri, H. Simonsen, B. Sander, A.E. Hansen, E. Rostrup, J. Frederiksen Neurology, 2011;77: Evaluation of dynamic contrast-enhanced T1-weighted perfusion MRI in the differentiation of tumor recurrence from radiation necrosis Vibeke A. Larsen, Helle J. Simonsen, Ian Law, Henrik B. W. Larsson, Adam E. Hansen Neuroradiology (2013) 55: Lectures: Magnetic Resonance used as a reach tool. Metropolitan University College, Copenhagen November 2008 Magnetic Resonance safety procedure - a training program for research students DSMMR s annual meeting, Middelfart, Denmark April 2011 Magnetic Resonance Metropolitan University College, Copenhagen, December 2011 Quality control on your MR system DSMMR s annual meeting, Vejle, Denmark April 2013 Organized curses: Magnetic Resonance Symposium, Functional Imaging Unit, Glostrup Hospital, Copenhagen, January 2007 Danish Society for Magnetic Resonance, one day course, Hotel Hesselet, Nyborg, Marts 2007 Danish Society for Magnetic Resonance, one day course, Torvehallerne, Vejle, Marts 2008 Danish Society for Magnetic Resonance, one day course, Hotel Ebeltoft Strand, Ebeltoft, Marts 2009 NordForsk Research Training course: Exploring Brain activation with BOLD imaging, Faculty of Health Sciences University of Copenhagen, Blegdamsvej, Copenhagen, September 2010 Danish Society for Magnetic Resonance, one day course, Middelfart Byggecentrum, Middelfart, Marts 2010 Danish Society for Magnetic Resonance, MR Clinical Basis Course, a four day course, Frederikskaj, Copenhagen, June 2010 (Organizer and chair). Magnetic Resonance Symposium, Functional Imaging Unit, Glostrup Hospital, Copenhagen, February 2011 Danish Society for Magnetic Resonance, one day course, Middelfart Byggecentrum, Middelfart, April 2011 Perfusion Symposium, Nordic Neuro Lab and Functional Imaging Unit, Glostrup Hospital, Copenhagen, January 2012

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6 ISMRM and SMRT meetings: ISMRM Fifth Scientific Meeting and Exhibition, Vancouver, Canada, April 1997 ISMRM Seventh Scientific Meeting and Exhibition, Philadelphia, Pennsylvania, USA, May 1999 ISMRM Eighth Scientific Meeting and Exhibition. Denver, Colorado, USA, April 2000 SMRT & BAMRR Tenth Annual Meeting, Glasgow, Scotland, UK, April 2001 ISMRM 9th. Scientific Meeting and Exhibition, Glasgow, Scotland, UK, April 2001 ISMRM Weekend Educational, Honolulu, Hawaii, USA, May 2002 ISMRM Tenth Scientific Meeting and Exhibition, Honolulu, Hawaii, USA, May 2002 SMRT & BAMRR Twelfth Annual Meeting, Metro Toronto Convention Centre, Toronto, Ontario, Canada, July 2003 ISMRM Eleventh Scientific Meeting and Exhibition, Metro Toronto Convention Centre, Toronto, Ontario, Canada, July 2003 ISMRM Workshop on MR Technology to Assess MS Pathology In Vivo, San Servolo, Venice, Italy, October 2003 SMRT & BAMRR Thirteenth Annual Meeting, Kyoto Convention Centre, Kyoto Japan, May 2004 ISMRM Twelfth Scientific Meeting and Exhibition, Kyoto Convention Centre, Kyoto Japan, May 2004 ESMRMB 21st Annual Meeting Copenhagen, Denmark, September 2004 SMRT & BAMRR Fourteenth Annual Meeting, Miami Beach Convention Centre, Miami, Florida, May 2005 ISMRM Thirteenth Scientific Meeting and Exhibition, Miami Beach Convention Centre, Miami, Florida, May 2005 SMRT & BAMRR Fifteenth Annual Meeting, Washington State Convention & Trade Center, Seattle, Washington, USA, May 2006 ISMRM Fourteenth Scientific Meeting and Exhibition, Washington State Convention & Trade Center, Seattle, Washington, USA, May 2006 SMRT & BAMRR 16th Annual Meeting, Berlin International Congress Center, Berlin, Germany, May 2007 ISMRM Fourteenth Scientific Meeting and Exhibition 15th Annual Meeting, Berlin International Congress Center, Berlin, Germany, May 2007 SMRT & BAMRR 17th Annual Meeting, Metro Toronto Convention Centre, Toronto, Ontario, Canada, May 2008 ISMRM Fifteenth Scientific Meeting and Exhibition, Metro Toronto Convention Centre, Toronto, Ontario, Canada, May 2008 SMRT & BAMRR 18th Annual Meeting Hawaii Convention Center, Honolulu, Oahu, USA, April 2009 ISMRM 17th Scientific Meeting and Exhibition Hawaii Convention Center, Honolulu, Oahu, USA, April 2009 SMRT & BAMRR 19th Annual Meeting, Stockholmsmässan AB (Stockholm International Fairs), Stockholm Sweden, May 2010 ISMRM 18th Scientific Meeting and Exhibition, Stockholmsmässan AB (Stockholm International Fairs), Stockholm Sweden, May 2010

7 SMRT & BAMRR 20th Annual Meeting, Palais des congrès de Montréal, Montréal, Québec, Canada, May 2011 ISMRM 19th Scientific Meeting and Exhibition, Palais des congrès de Montréal, Montréal, Québec, Canada, May 2011 SMRT & BAMRR 21th Annual Meeting, Melbourne, Victoria, Australien, May 2012 ISMRM 20th Scientific Meeting and Exhibition, Melbourne, Victoria, Australien, May 2012 ISMRM workshop, MR Safety, now and in the future, Lund, Sweden, September 2012 SMRT & BAMRR 22th Annual Meeting, Melbourne, Salt Lake, Utah, USA, May 2013 ISMRM 21th Scientific Meeting and Exhibition, Melbourne, Salt Lake, Utah, USA, May 2013 ESMRMB 30 st Annual Meeting, Toulouse; France, October 2013

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