Department of Ophthalmology University of Tampere. Chief Physician Tays Eye Center Tampere University Hospital

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1 Curriculum vitae: U u s i t a l o, Hannu Mauno Tapio: Present Post: Professor and Chairman Department of Ophthalmology University of Tampere Chief Physician Tays Eye Center Tampere University Hospital Director SILK Research Center for Ophthalmic Innovations Chief Medical Officer The Finnish Register of Visual Impairment FinnMedi Oy Senior Consultant Home: Silmäkkeenkatu 1 B Tampere Tel Fax Mobile phone Office: Department of Ophthalmology University of Tampere School of Medicine ARVO B Tampereen yliopisto puh Time of birth: Place of birth: Family: Education: Helsinki married in Leni Uusitalo daughter - Johanna 1981 son - Jaakko 1987 Matriculation examination Lahden Lyseo

2 Bachelor of Medicine University of Helsinki Licenciate of Medicine (M.D.) University of Helsinki Doctor in Medicine and Surgery (Ph.D.) University of Helsinki Docent in Microscopic Anatomy University of Helsinki Professor Competence in Cell Biology University of Oulu Docent in Anatomy University of Tampere Specialist in Ophthalmology University of Tampere Docent in Ophthalmology University of Tampere Present Post Department of Ophthalmology University of Tampere Professor in Ophthalmology Tays Eye Center Tampere University Hospital Chief Physician FinnMedi Oy Senior Consultant Former Posts as a University Teacher: University of Helsinki Department of Anatomy Assistant years 4 months University of Helsinki Department of Anatomy Lecturer years 10 months University of Helsinki

3 Former Posts as Visiting Teacher at University: Department of Anatomy Associate Professor months University of Tampere Medical School Department of Ophthalmology Lecturer years 11 months University of Kuopio Department of Ophthalmology Professor and Chairman University of Helsinki, Department of Anatomy, Visiting teacher year 2 months Other Teaching Merits: University of Helsinki, Department of Pharmacy, Visiting teacher months University of Helsinki, Faculty of Medicine Member of Education Committee University of Tampere, Faculty of Medicine, Planning Group Member for the period: The Prosessing of external and internal Signals University of Tampere, Faculty of Medicine, Tutor Course of Problem Based Learning 1996 University of Tampere, Faculty of Medicine, The Group Teacher of the Year 1999 University of Kuopio, Faculty of Medicine Member of Specialist Education Committee University of Kuopio, Faculty of Medicine Member of Scientific Education Committee Vice Chairman University of Kuopio, Member of Advisory Board of University Innovations

4 Scientific and Educational Merits: A) Scientific Publications: See list of publications B) Lecturer in International Meetings for Eye Research and Ophthalmology: Association for Research in Vision and Ophthalmology (ARVO) Meeting, Southern Section, New Orleans, 1980 VI International Congress of Histo- and Cytochemistry, Brighton, 1980 Association for Eye Research Meeting, St Andrews, Scotland, 1981 International Congress of Eye Research (ICER), Nijmegen, The Netherlands, 1982 Association for Eye Research Meeting, Wien, Austria, 1983 VI International Congress of Eye Research (ICER), Alicante, Spain, 1984 Scandinavian Neurohistochemistry Meeting, Helsinki 1985 VII International Congress of Eye Research (ICER), Nagoya, Japan, 1986 Association for Eye Research Meeting, Leuven, Belgium, 1987 VIII International Congress of Eye Research (ICER), San Francisco, USA, 1988 XXIX Nordic Ophthalmology Meeting, Reykjavik, Iceland, 1989 XXX Association for Eye Reserach Meeting, Montpelier, France, 1989 IX International Congress of Eye Research (ICER) Meeting, Helsinki, Finland, 1990 Symposium on Pharmacologically Active Peptides, Espoo, Finland, 1991 Symposium on Methods to Overcome Biological Barriers in Drug Delivery, Kuopio, 1993 Norwegian Ophthalmologic Society Meeting, Bergen, 1995

5 Societas Ophthalmologica Europea, Budapest, Hungary, EGS Glaucoma Symposium, Wurzburg, Germany, rd International Symposium on Ocular Pharmacology and Pharmaceutics- ISOPP, Lissabon, Portugal, VI Congress on the Europian Glaucoma Society, London, UK, XXXIV Nordic Congress of Ophthalmology, Reykjavik, Iceland, rd International Glaucoma Symposium, Prag, Czech Republic, I European Glaucoma Specialist Meeting, Rome, Italia, XXXV Nordic Congress of Ophthalmology, Tampere, 2002 XXXVI Nordic Congress of Ophthalmology, Malmö, Sweden, 2004 EVER Meeting, Vilamoura, Portugal, EVER Meeting, Vilamoura, Portugal, XXXVII Nordic Congress of Ophthalmology, Copenhagen, EVER Meeting, Portoroz, Slovenia, 2007 EVER Meeting, Portoroz, Slovenia, 2008 Societas Ophthalmologica Europea (SOE) Meeting, Amsterdam, June 12-15, International Congress of Glaucoma Surgery, Geneva Switzerland. April 16-18, World Glaucoma Congress, Boston, USA. July SILK-Elsemay Björn Symposium, Tampere, Aug 18, 2009 EVER Meeting, Portoroz, Slovenia, SILK-Elsemay Björn Symposium, Tampere, Aug 18, 2009 EVER Meeting, Hersonissos, Crete, Oct

6 American Academy of Ophthalmology (AAO), Chigaco, USA. Oct , 2010 Asian Cornea Symposium, Kyoto, Japan. Jan 1.-3., Societas Ophthalmologica Europea (SOE) Meeting, Geneva, June 3.-6., World Glaucoma Congress, Paris, SILK-Elsemay Björn Symposium, Tampere, Aug 16, EVER Meeting, Hersonissos, Crete, Oct Polish Glaucoma Society Meeting, Wisla, Poland. March Association for Research in Vision and Ophthalmology (ARVO) Meeting, Fort Lauderdale, USA. May Nordic Congress of Ophthalmology, Helsinki, Aug SILK-Elsemay Björn Symposium, Tampere, Aug 15, 2012 EVER Meeting, Nice, Sept White Night Symposium, St Petersburg May Societas Ophthalmologica Europea (SOE) Meeting, Copenhagen, June 12-15, SILK-Elsemay Björn Symposium, Tampere, Aug 20, EVER Meeting, Nice, Sept International Congress of Glaucoma Surgery, Singapore. Feb 20-22, C) Lecturer in Domestic Ophthalmological Meetings: Finnish Ophthalmological Society Meeting, 1983, Espoo, Hanasaari Paikallisen silmälääkinnän annosmuodot ja farmakokinetiikka Symposium, University of Kuopio, 1984 Finnish Ophthalmological Society Autumn Meeting, 1984

7 Työnäkeminen ja valaistus Symposium University of Tampere,1985 Näkeminen ja liikenne Symposium Suomen Liikennelääketieteen Yhdistys r.y. Finnish Ophthalmological Meeting 1992, Tampere Finnish Ophthalmological Meeting 1993, Kuopio Tampereen lääkäripäivät, 1994, 1995, 1996 Medicine 96, Helsinki Medicine 97, Helsinki Finnish Ophthalmological Meeting 1997, Tampere Medicine 98, Helsinki Finnish Ophthalmologic Society Meeting 1999, Tampere Finnish Glaucoma Society Sprig Meeting 1999, Helsinki Tampereen lääkäripäivät 2000, Tampere Finnish Glaucoma Society Meeting 2000, Kittilä Finnish Ophthalmologic Society Meeting 2001, Helsinki Finnish Glaucoma Society Meeting, 2002, Kittilä Kliinisen Farmakologiyhdistyksen koulutuspäivät, Tampere Finnish Ophthalmologic Society Meeting, Kuopio, 2003 Finnish Glaucoma Society Meeting, Naantali, 2004 Tampereen Lääkäripäivät 2005, Tampere Tampereen Lääkäripäivät 2006, Tampere Lääketiede 2007, Helsinki Tampereen Lääkäripäivät 2007, Tampere Finnish Glaucoma Society Meeting, Helsinki, 2007 Finnish Ophthalmological Society Meeting, Tampere,2007. World Glaucoma Day Lecture, Tampere, March 6, 2008.

8 World Glaucoma Day Lecture, Tampere, March 12, Tampereen Lääkäripäivät 2009, Tampere Synapsi Symposium, Oulu. Jan 29, 2010 Visual Rehabilitation. 20 Year Anniversary Symposium, Tampere. Feb 20, World Glaucoma Day Lecture, Tampere, March 12, World Glaucoma Day Lecture, Tampere, March 10, Tampereen Lääkäripäivät 2011, Tampere, March Finnish Glaucoma Society Meeting, Helsinki, March , Finnish Ophthalmological Society Meeting, Helsinki, Lumina Symposium, Tampere Jan 27, World Glaucoma Day Lecture, Tampere, March 14, Finnish Glaucoma Society Meeting, Helsinki, April 20, World Glaucoma Day Lecture, Tampere, March 12, Finnish Glaucoma Society Meeting, Helsinki, April 24, 2013 Universanten- Symposium, Tampere May 17, Finnish Ergophthalmological Society Symposium, Helsinki, Jan 23, 2014 World Glaucoma Day Lecture, Tampere, March 11, Tampereen Lääkäripäivät 2014, Tampere, March Universanten- Symposium, Kuopio March 21, D) Organizer in Scientific Meetings and Symposia of Eye Research and Ophthalmology: Symposium of Ophthalmic Research, Helsinki Speakers: H.E.Kaufman, A.Palkama, R.Uusitalo, V.Laaka, J.Lehtosalo, J.Virtanen, ja H.Uusitalo Adrenergic Nervous System and Intraocular Pressure, Symposium, Helsinki

9 -Speakers: M.Sears, A.Alm, A.Tarkkanen ja A.Palkama International Society of Refractive Keratoplasty Meeting, Helsinki, 1984 Symposium of Beta-Adrenergic Blockade and Intraocular Pressure, Helsinki Speakers: O.Valle, J.Stjernschantz, T.Mittag, A.Palkama, R.Uusitalo, T.Puustjärvi, M.Tost ja A.Alm Symposium of Basic Research in Ophthalmology, Helsinki Speakers: B.Ehinger, S.Nilsson, K.Krootila ja K.Mahlberg Symposium of Refractive Surgery, Helsinki Speakers: H.Kaufman, R.Uusitalo ja J.Lehtosalo IX International Congress of Eye Research, Helsinki, General Secretary, Editor-in-chief. The Ocular Functions of Eicosanoids and Other Lipid Mediators, Porvoo, Board. Symposium on Pharmacologically Active Peptides, , Espoo, Finland. Board. Finnish Ophthalmologic Society Meeting, , Tampere, Finland. Board. Medicine 1997, The Meeting of Finnish Medical Association,. Ocular Trauma Symposium. Board. Medicine The Meeting of Finnish Medical Association, Ophthalmology for General Practioners Symposium. Chairman Nordic Glaucoma Meeting 1998, Helsinki, Finland. Board. Finnish Glaucoma Society Spring Meeting 1999, Helsinki. Board. Finnish Glaucoma Society Spring Meeting 2000, Kittilä. Board. Finnish Ophthalmological Society Meeting 2001, Helsinki. Board. XXXV Nordic Meeting of Ophthalmolgy, NOK Chairman of Scientific Committee, 2002, Tampere, Finland. Finnish Ophthalmological Society Meeting Chairman, Kuopio, Finland.

10 EVER Meeting, Villamoura, Portugal, SIS Symposium Organizer 2005 Finnish Ophthalmological Society Spring Meeting, President, Helsinki 2006 Finnish Ophthalmological Society Meeting, President, Helsinki, 2006 EVER Meeting, Villamoura, Portugal, SIS Symposium Organizer, Medicine 2007 The Meeting of Finnish Medical Association, Ophthalmology for General Practioners. Symposium Chairman, Helsinki Finnish Ophthalmological Society Spring Meeting, President, Helsinki 2007 Finnish Ophthalmological Society Meeting, President, Tampere, 2007 EVER Meeting, SIS Symposium Organizer, Portoroz, Slovenia, 2007 EVER Meeting, SIS Symposium Organizer, Portoroz, Slovenia, 2008 SILK-Elsemay Björn Symposium, Tampere, Organizer, Aug 18, 2009 EVER Meeting, Portoroz, Slovenia, SIS Symposium Organizer, SILK-Elsemay Björn Symposium, Organizer, Tampere, Aug 18, 2009 EVER Meeting, Hersonissos, Crete, SIS Symposium Organizer, Oct SILK-Elsemay Björn Symposium, Tampere, Aug 16, EVER Meeting, Hersonissos, Crete, SIS Symposium Organizer, Oct Nordic Congress of Ophthalmology, Helsinki, Member of The Scientic Program Committee, Aug SILK-Elsemay Björn Symposium, Organizer, Tampere, Aug 15, 2012

11 EVER Meeting, Nice, SIS Symposium Organizer, Sept Lumina Symposium, Tampere Jan 25, EVER Meeting, Nice, SIS Symposium Organizer, Sept Lumina Symposium, Tampere, Organizer, Jan 31, World Glaucoma Day Lecture, Tampere, Organizer March 11, Tampereen Lääkäripäivät 2014, Tampere, Symposium Organizer, March Supervisor of Scientific Studies: Academic Thesis Studies: Kari Krootila M.D., Ph.D. (1988) Antero Salo M.D., D.O., Ph.D. (1995) Jyrki Törnwall M.D., D.O., Ph.D. (1996) Antti Tuori M.D., Ph.D. (1998) Heikki Lamminen M.D., M.Sc. (2001) Anne Huhtala, D.Sc (Tech) (2003) Päivi Alajuuma, Ph.D (2004). Kati Kinnunen (2009) Tuomas Ryhänen Ph.D. (2011) Juhani Pietilä M.D. Ph.D. (2012) 10 ongoing thesis studies: Petri Mäkinen Minna Helin Juhana Laine Marja-Leena Latvala Hillevi Blomster Minna Parkkari Mikael Suviola Virpi Hemminki Matti Seppänen Tuukka Felin Special Research Studies: Antero Salo Timo Scultz Rauli Tolonen Jussi Luhtala

12 Erkki Virta Sami Kangas Jyrki Törnwall Antti Tuori Tiina Lajunen Jukka Terttunen Petri Mäkinen Juho Nummi Jouni Mäkinen Sami Mäntykorpi Juho Keski-Nisula Kalle Sipilä Sami Nurmi Pasi Ylitepsa Ilkka Törmänen Lotta Mononen Risto Mustalahti Tuulia Palukka Tommi Härkönen Pro gradu Studies: Auli Linnala Petri Kiviluoma Taina Santala Erika Oksala Scientific Referee: Referee of Academic Thesis (Hanna Tainio, M.D.) University of Tampere, Faculty of Medicine,1987. Referee of Docentship Pauli Hele'n (M.D., Ph.D.), University of Tampere, Faculty of Medicine, Opponent of Dissertation (Kerstin Wickström M.D.), University of Uppsala, Sweden 1992 Opponent of Dissertation (Jaana Suhonen, M.D.), University of Tampere, Faculty of Medicine, Referee of Academic Thesis (Kari Mäkinen, M.Sc), Tampere University of Technology, 1995 Referee of Academic Thesis (Pekka Suhonen M.Sc), University of Kuopio, Faculty of Pharmacy, 1996 Referee of Academic Thesis (Päivi Rouhiainen, M.D.), University of Kuopio, Faculty of Medicine, 1996 Opponent of Dissertation (Terho Latvala. M.D.), University of Helsinki, Faculty of Medicine, 1996

13 Opponent of Dissertation (Matti Kivalo, D.V.), University of Helsinki, Faculty of Veterinary, 1998 Referee of Academic Thesis (Reijo Linnola, M.D.), University of Oulu, Faculty of Medicine, 2001 Referee of Academic Thesis (Tuula Pohjalainen M.D.), University of Helsinki, Faculty of Medicine, 2001 Opponent of Dissertation (Iiris Sorri, M.D.), University of Kuopio, Medical Faculty, 2001 Referee of Docentship (Päivi Puska, M.D.), University of Helsinki, Faculty of Medicine, Referee of Academic Thesis (Valtteri Aho M.D.), University of Turku, Faculty of Medicine, Referee of Docentship (Marja-Liisa Vuori, M.D.), University of Turku, Faculty of Medicine, Referee of Academic Thesis (Sirpa Loukovaara, M.D.), University of Helsinki, Faculty of Medicine, Referee of Professorship in Ophthalmology, University of Tartu, 2003 Opponent of Dissertation (Elina Vainio-Jylhä, M.D.) Univeristy of Turku, Faculty of Medicine, Referee of Docentship (Marko Määttä, M.D)., University of Helsinki, Faculty of Medicine, Opponent of Dissertation (Sissi Katz, M.D.), Univeristy of Helsinki, Faculty of Medicine, Opponent of Dissertation (Jukka Saari, M.D.), University of Helsinki, Faculty of Medicine, Referee of Academic Thesis (Ilpo Tuisku M.D.), University of Helsinki, Faculty of Medicine, Opponent of Dissertation (Jukka Koistinen, M.D.), University of Helsinki, Faculty of Medicine, Opponent of Dissertation (Satu Länsman, M.D.), University of Oulu, Faculty of Medicine, Opponent of Dissertation (Eliisa Mannermaa, M.D.), University of Eastern Finland, Faculty of Healt Sciences, 2010.

14 Opponent of Dissertation (Jukka Nevalainen, M.D.), University of Oulu, Faculty of Medicine, Opponent of Dissertation (Kati-Sisko Vellonen, Ph.D) University of Helsinki, Faculty of Pharmacy, 2010 Referee of Academic Thesis (Ville Saarela, M.D.) University of Oulu, Referee of Docentship (Johanna Liinamaa, M.D.) University of Oulu, Academic Positions of Trust: University of Helsinki, Faculty of Medicine, Member of Education Committee University of Helsinki, Faculty of Medicine, Board Member of Medical Faculty University of Tampere, Faculty of Medicine, Board Member of Medical Faculty University of Tampere, Faculty of Medicine, Member of Scientific Committee University of Kuopio, Faculty of Medicine Member of Specialist Education Committee University of Kuopio, Faculty of Medicine Member of Scientific Education Committee Vice Chairman University of Kuopio, Member of Advisory Board of University Innovations University of Kuopio, Chairman of the Grant Committee University of Tampere, Faculty of Medicine Member of Specialist Education Committee Board of the Medical School, University of Tampere Board Member Memberships in International and Domestic Scientific Organizations: Finnish Association for Eye Research Secretary Vice President 1994-

15 SOE (Societas Ophthalmologica Europae, European Ophthalmology) Board Member Association for Eye Research Association for Research in Vision and Ophthalmology International Society of Eye Research Finnish Association of Histochemistry and Cell Biology Member of Board th International Congress of Eye Research General Secretary Society for Neuroscience Scandinavian Society for Refractive Surgery International Society of Refractive Surgery European Society of Cataract and Refractive Surgeons American Academy of Ophthalmology Finnish Ophthalmological Society Member of Board President Finnish Glaucoma Society Treasurer President Memberships of Board of Ophthalmological Journals Journal of Refractive Surgery -Member of Editorial Board Acta Ophthalmologica -Member of Editorial Board Member of Board Other Positions of Trust: Lahden Lyseo, (Senior High School). President of School Board Finnish Military Officer School. Chairman of the Medical Student Body 1985 President of Tampere Medical Doctor Association Military Merits: Second Lieutenant in Finnish Navy

16 Finnish Military Officer School, Sword of Honor (Primus), Course 177, GCP Education Kliiniset Lääketutkimukset (Clinical GCP Course) Duodecim, Gustavelund, Tuusula Finland , Pfizer Oy GCP Course, 2002, Kuopio, Finland

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