Innovative Link in Microbiology

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1 main-gold@oskon.co.th Innovative Link in Microbiology

2 Bioengineering AG: WALD Switzerland Founded: main-gold@oskon.co.th

3 Smallest Fermenter: 500 ml Largest Fermenter Design: 500 m 3 Largest Fermenter Built: 240 m 3 Largest Cell Fermenter Built: 15 m 3

4 Complete fermenter system including up and down stream Suitable for Microbial, Yeast, Algae, Plant and Animal cell Engineering, Manufacturer Eq uipment for sterile application

5 KLF (In-situ Sterilization) L1523 (In-situ Sterilization) R ALF (Autoclavable Laboratory Fermenter)

6 KLF (In-situ Sterilization) Fixed Speed Peristaltic Pump Glass Cylinder Variable Speed Peristaltic Pump Computer Control Driving Motor

7 KLF (In-situ Sterilization) with DDC Control Sterilized in-situ with electrical heating (800 W heating finger) and safety jacket Three interchangeable glass cylinder with volumes of 2.4, 3.1 and 3.7 liters Design to cultivation of bacteria, yeast, mold, plant or animal cells Top or bottom drive; Single or double mechanical seal (magnetic drive available as option)

8 KLF (In-situ Sterilization) with IFM Control Septa for needle connections (acid, base, air inlet and exhaust, medium, etc.) Sterile connector 12 mm or 19 mm in the lid and bottom Instrumentation and control system for ph, po 2, temperature, antifoam, pressure and level electrodes Operating temperature o C Operating pressure barg

9 KLF (In-situ Sterilization) with IFM Control

10 R ALF (Autoclavable Laboratory Fermenter) Top drive Motor Fixed Speed Peristaltic Pump Variable Speed Peristaltic Pump Glass Vessel with double jacket

11 R ALF Plus Quartet (Autoclavable Laboratory Fermenter)

12 R ALF (Autoclavable) with DDC Control Autoclaveable laboratory fermenter Interchangeable glass vessel in sizes 0.5, 1, 2, 3.7, 5, 6.7 and 15 liters Top drive with mechanical seal Glass vessel with double jacket individual temperature control

13 R ALF (Autoclavable) with DDC Control Motor speed range rpm Operating temperature max. 80 o C Operating pressure max. 1.5 barg Glass vessel material: borosilicate glass Contacted part material: SS316L

14 L1523 (In-situ Sterilization) Glass Cylinder IFM Controller Built-in Table

15 L1523 (In-situ Sterilization) Sterilized in-situ Built into standard table Interchangeable steel or glass cylinders volumes from 5 to 19 liters Design to cultivation of bacteria, yeast, mold, plant or animal cells Top or bottom drive; Single or double mechanical seal

16 Motor speed range rpm Operating temperature max. 150 o C Operating pressure max. (glass cylinder): 1.5 barg, (steel cylinder): 2.5 barg A double wall dish to control temperature Contacted part material: SS316L

17 NLF22 (Sizes Liters) Type P (Sizes 100-1,000 Liters) LP351 (Sizes Liters)

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20 NLF22 (Sizes Liters) Total volume Glass Cylinder: 16, 19 and 22 Liters Stainless steel: 16, 19 and 30 Liters Working volume Glass Cylinder: 10.6, 12.6 and 14.6 Liters Stainless steel: 10.6, 12.6 and 20 Liters Controller ph, po 2, Temperature, Agitation, Level, Antifoam, Pressure and Weight

21 LP351 (Sizes Liters) Total volume Stainless steel: 42, 50 and 75 Liters Working volume Stainless steel: 28, 33 and 50 Liters Controller ph, po 2, Temperature, Agitation, Level, Antifoam, Pressure and Weight

22 Type P (Sizes 100-1,000 Liters) Total volume Stainless steel: 100, 150, 200, 300, 450, 750 and 1,000 Liters Working volume Stainless steel: 65, 100, 130, 200, 300, 500 and 650 Liters Controller ph, po 2, Temperature, Agitation, Level, Antifoam, Pressure and Weight

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24 IFM = Intelligent Front Module. Available for Temp, speed, ph, po 2, Antifoam, Level,pressure, weight, etc controller Trend and Setpoint value Display Multi-level password protection for various functions The PC and IFM display module communicate via RS-485 interfaces IFM Housing : Aluminum Manual, Setpoint, Profile and Cascade control

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29 CIP Mobile Unit CIP Valve Diaphragm Valve Inversina Peristaltic Pump Magnetic Stirrer Spiral filter

30 CIP (Clean In Place) Mobile Unit

31 CIP Mobile Unit, Fully Automized Mobile cleaning station to service production equipment Compact System Automated Process Control Selection of up to 28 steps Reproduceability Modular Design 2 tanks for rinsing water and cleaning solution 2 containers for detergent concentrate Connections for 2 water qualities Pumps Heat exchange and armatures Control cabinet PC (Laptop)

32 CIP Mobile Unit, Manual For dosage of CIP solutions into the fermenter Use of the fermenter/vessel for mixing and temperature control Simple set-up 2 dosing vessels for detergent solutions with pump 2 containers for detergent concentrate Circulation pump Connections for water, air, drain

33 Peristaltic Pumps (Peripex) Peristaltic pumps are particularly well suitable to feed shear-sensitive, toxic or foamy fluids

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