Daclatasvir, Asunaprevir, and Peginterferon Lambda (Hepatitis C Virus) - Forecast and Market Analysis to

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1 Brochure More information from Daclatasvir, Asunaprevir, and Peginterferon Lambda (Hepatitis C Virus) - Forecast and Market Analysis to 2022 Description: Daclatasvir, Asunaprevir, and Peginterferon Lambda (Hepatitis C Virus) - Forecast and Market Analysis to 2022 Summary Hepatitis C is a liver infection caused by the hepatitis C virus (HCV) that results in acute or chronic presentation. The disease is often asymptomatic, but infected patients may experience fatigue, joint pain, itchy skin or jaundice. There is no effective vaccine against HCV, so the market is driven by therapeutics. Daclatasvir is a DAA being developed by BMS for the treatment of HCV infection. The mechanism of action of daclatasvir involves the inhibition the NS5A protein. NS5A is unique to HCV, and the protein is essential for multiple functions in the viral lifecycle, including HCV RNA replication, despite not having any enzymatic activity. Scope - Overview of Hepatitis C, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape. - Detailed information on Daclatasvir, Asunaprevir, and Peginterferon Lambda including product description, safety and efficacy profiles as well as a SWOT analysis. - Sales forecast for Daclatasvir, Asunaprevir, and Peginterferon Lambda for the top nine countries from 2012 to Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan, Brazil and China. Reasons to buy - Understand and capitalize by identifying products that are most likely to ensure a robust return - Stay ahead of the competition by understanding the changing competitive landscape for Hepatitis C - Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential - Make more informed business decisions from insightful and in-depth analysis of Daclatasvir, Asunaprevir, and Peginterferon Lambda performance - Obtain sales forecast for Daclatasvir, Asunaprevir, and Peginterferon Lambda from in top nine countries (the US, France, Germany, Italy, Spain, the UK, Japan, Brazil and China). Contents: List of Tables 1.2 List of Figures 2 Introduction 2.1 Catalyst 2.2 Related Reports 2.3 Upcoming Related Reports 3 Disease Overview 3.1 Etiology and Pathophysiology Etiology Pathophysiology Prognosis 3.2 Symptoms 4 Disease Management 4.1 Diagnosis and Referral Overview 4.2 Treatment Overview 5 Competitive Assessment

2 5.1 Overview 5.2 Strategic Competitor Assessment 6 Opportunity and Unmet Need 6.1 Overview 6.2 Unmet Needs Unmet Need: Treatment Tolerability Unmet Need: Efficacy Unmet Need: Disease Awareness Unmet Need: Treatment Cost Unmet Need: Shorter Treatment Duration Unmet Need: Simplified Treatment Regimens 6.3 Unmet Needs Gap Analysis 6.4 Opportunities Opportunity: Pan-genotypic HCV Regimen Opportunity: Treatment of Underrepresented Patient Populations Opportunity: Involvement of Immune System 7 Pipeline Assessment 7.1 Overview 7.2 Promising Drugs in Clinical Development 8 Daclatasvir, Asunaprevir, and Peginterferon Lambda 8.1 Overview 8.2 Efficacy 8.3 Safety 8.4 Dosing and Formulation 8.5 Potential Clinical Positioning 8.6 Potential Commercial Positioning 8.7 Pricing and Reimbursement 8.8 SWOT Analysis 8.9 Forecast 9 Appendix 9.1 Bibliography 9.2 Abbreviations 9.3 Methodology 9.4 Forecasting Methodology Percent Drug-Treated Patients Patient Warehousing General Pricing Assumptions Generic Erosion Pricing of Pipeline Agents 9.5 Physicians and Specialists Included in this Study 9.6 Survey of Prescribing Physicians 9.7 About the Authors Author Global Head of Healthcare 9.8 About Us 9.9 Contact Us 9.10 Disclaimer 1.1 List of Tables Table 1: Modes of HCV Transmission Table 2: Symptoms of Acute and Chronic HCV Infection Table 3: HCV Genotypes Present in the 9MM Table 4: General Standard of Care by HCV Genotype Table 5: Treatment Guidelines for HCV by Country Table 6: Most-Prescribed Drugs for HCV by Class in the Global Markets, 2013 Table 7: Leading Treatments for HCV, 2012 Table 8: Overall Unmet Needs Current Level of Attainment Table 9: Clinical Unmet Needs Gap Analysis, 2012 Table 10: HCV Pipeline, 2012 Table 11: Comparison of Therapeutic Classes in Development for HCV, 2012 Table 12: Bristol-Myers Squibb s Daclatasvir Ongoing Clinical Trials of Interest Table 13: Product Profile Daclatasvir Table 14: Efficacy of Daclatasvir in Treatment-Naïve Patients (COMMAND-1 Trial)

3 Table 15: Daclatasvir and Asunaprevir Quad Therapy Efficacy Table 16: Daclatasvir Triple Therapy Adverse Events Table 17: Daclatasvir SWOT Analysis, 2012 Table 18: Global Sales Forecasts ($m) for Daclatasvir, Asunaprevir, and Peginterferon Lambda, Table 19: Physicians Surveyed, By Country 1.2 List of Figures Figure 1: HCV Genome and Polyprotein Composition Figure 2: HCV Lifecycle Overview Figure 3: Competitive Assessment of Late-Stage Pipeline Agents in HCV, Ordering: Order Online - Order by Fax - using the form below Order by Post - print the order form below and send to Research and Markets, Guinness Centre, Taylors Lane, Dublin 8,

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5 Page 2 of 2 Payment Information Please indicate the payment method you would like to use by selecting the appropriate box. Pay by credit card: You will receive an with a link to a secure webpage to enter your credit card details. Pay by check: Please post the check, accompanied by this form, to: Research and Markets, Guinness Center, Taylors Lane, Dublin 8, Pay by wire transfer: Please transfer funds to: Account number Sort code Swift code IBAN number Bank Address ULSBIE2D IE78ULSB Ulster Bank, Main Street, Blackrock, Co. Dublin, If you have a Marketing Code please enter it below: Marketing Code: Please note that by ordering from Research and Markets you are agreeing to our Terms and Conditions at Please fax this form to: (646) or (646) From USA or From Rest of World

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