Stereotactic Body Radiation Therapy for Prostate Cancer
|
|
- Candice Howard
- 7 years ago
- Views:
Transcription
1 Stereotactic Body Radiation Therapy for Prostate Cancer Alexander R. Gottschalk, M.D., Ph.D. Associate Professor and Director of the CyberKnife Radiosurgery Program Department of Radiation Oncology University of California, San Francisco April 2, 2011 UC SF What is SBRT? Stereotactic body radiotherapy is not: 2D (AP/PA or postage-stamp field ) 3DCRT (4 fields) Intensity-modulated radiotherapy () Protons Stereotactic body radiotherapy is: Converging multiple beams on the tumor Resulting in a very conformal dose distribution Limiting dose to normal tissue Allowing for higher dose delivered to the tumor Delivered in a hypofractionated regimen (high-dose per fraction and few number of fractions) What is SBRT? SBRT is a treatment that couples a high degree of anatomic targeting accuracy and reproducibility with very high doses of extremely precise, externally generated, ionizing radiation, thereby maximizing the cell-killing effect on the target(s) while minimizing radiationrelated injury in adjacent normal tissues. The adjective stereotactic describes a procedure during which a target lesion is localized relative to a known three dimensional reference system that allows for a high degree of anatomic accuracy and precision. Examples of devices used in SBRT for stereotactic guidance may include a body frame with external reference markers in which a patient is positioned securely, a system of implanted fiducial markers that can be visualized with low-energy (kv) x-rays, and CT-imagingbased systems used to confirm the location of a tumor immediately prior to treatment. What is SBRT? All SBRT is performed with at least one form of image guidance to confirm proper patient positioning and tumor localization. To minimize intra-treatment tumor motion associated with respiration or other motion, some form of motion control or gating may be used. SBRT may be fractionated (up to 5 fractions). Each fraction requires an identical degree of precision, localization and image guidance. Since the goal of SBRT is to intensify the potency of the radiotherapy by completing an entire course of treatment within an extremely accelerated time frame, any course of radiation treatment extending beyond five fractions is not considered SBRT and is not to be billed using these codes. Page 1
2 Hypofractionation for Prostate Cancer Hypofractionation for Prostate Cancer Why hypofractionation? Shorter treatment More effective treatment? BED = nd[1 + d/(α/β)] Why hypofractionation? Shorter treatment More effective treatment? BED = nd[1 + d/(α/β)] BED Fractionation α/β = 10 α/β = 3 α/β = Gy x 44 = 79.2 Gy Gy x 39 = 78 Gy Gy x 5 = 33.5 Gy Gy x 5 = Gy Gy x 4 = 38 Gy Hypofractionation for Prostate Cancer Hypofractionation for Prostate Cancer Are these dose for prostate cancer is new? Are these dose for prostate cancer is new? High dose per fraction has been use safely and effectively with brachytherapy (HDR) Page 2
3 HDR brachytherapy SBRT vs HDR brachytherapy 5-Year bdfs Outcomes for HDR-Monotherapy for Prostate Cancer HDR Details Institution # pts Medianf/u Phoenix ASTRO Gy x 6 CA Endocurie yrs 97% 9.5 Gy x 4 Beaumont % 7.5 Gy x 6 Texas Tech % 6.5 Gy x 6 Texas/Miami %* 99%* Gamma West SLC %* 89%* 6 Gy x 8-9 Osaka (Japan) % Totals % Toxicity review for HDR-Monotherapy for Prostate Cancer toxicity > Grade 2 HDR Details Institution # pts Median f/u GI (%) GU (%) Gy x 6 CA Endocurie Gy x 4 Beaumont Gy x 6 Texas Tech * 6.5Gy x 6 Gamma West (SLC) Gy x 8-9 Osaka (Japan) Totals Deliver high-dose per fraction Allows for hypofractionated treatment Treatment can be completed in 4-5 fractions SBRT compared to HDR Less invasive Less anesthesia Less risk of bleeding and infection Less requirement for pain medication No overnight stay in the hospital Analogy to HDR as a boost (following whole pelvis RT) HDR brachytherapy as boost High dose group Less biochemical failures Less distant mets Improved DFS, CSS and OS IJROBP 66:416, 2006 IJROBP 66: , 2006 Page 3
4 HDR brachytherapy as boost is a standard therapy RTOG 0321 (PI: I.C. Hsu) Phase II clinical trial of EBXRT + HDR boost EBXRT 45 Gy HDR boost 9.5 Gy x patients Median f/u 29.6 m Grade 3 GI/GU toxicity in 2.5% Other grade 3 toxicities: hemorrhage, anemia, pylonephritis, proctalgia, ED Hsu IJROBP 78:751, 2010 HDR brachytherapy monotherapy N= 149 T1c/T2a, PSA < 10, GS < Pd (120 Gy) vs HDR 9.5 Gy x 4 Median follow-up 35 m Similar biochemical control at 3 yrs HDR (98%) vs Pd (97%) J Urol 171: , 2004 Dosimetric Comparison between HDR and CK Dosimetric Comparison between HDR and CK IJROBP 70: 1588, 2008 Jabbari IJROBP Dec 21, 2010 Page 4
5 Dosimetric comparison of CyberKnife and Dosimetry of protons vs CTV Rectum 19Gy 14.2Gy CK 3DCPT Bladder CK SBRT CTV Norm. Volume (%) CK SBRT Rectum IMPT Norm. Dose (%) Hossain IJROBP 78:58, 2010 IJROBP 69: , patients 6.7 Gy x 5 fractions over consecutive days T1c-T2a, GS 6, PSA 10 6 non-coplanar beams with 4-5 mm margin Median follow-up 41 m No patients with grade 3 GI/GU toxicity 4-yr bned 70% (ASTRO) and 90% (nadir +2) 304 patients 7 Gy x 5 fractions (n=35) 7.25 Gy x 5 (n=254) T1c-T2a, GS 6, PSA 10 CyberKnife with 4-5 mm margin Median follow-up 30 m One patient grade 3 GU toxicity Follow-up too short to report bned Madsen IJROBP 67:1099, 2009 Katz BMC Urol 10:1, 2010 Page 5
6 41 patients ( at Stanford and Naples, FL) Gy x 5 fractions T1c-T2b, GS 6, PSA 10 Treatment volume = prostate + 5mm (3mm posterior) Median follow-up 5 years 1 patient with late grade 3 GU toxicity No patients with grade 3 GI toxicity 5-year bpfs 93% PSA nadir < 0.4 (78%) Stanford experience 67 patients 7.25 Gy x 5 fractions over 10 days T1c-T2b, GS 7, PSA 10 Treatment volume = prostate + 5mm (3mm posterior) Median follow-up 2.7 yrs Grade 3 GU toxicity in 2 patients (3%) No patients with grade 3 GI toxicity Median PSA at last follow-up 0.5 ng/ml 4-year brfs 94% Freeman Radiation Oncol 6:3, 2011 King IJROBP Feb 5, patients (41 intermediate and 32 high-risk) 45 Gy EBRT followed by SBRT boost 6 Gy x 3 fractions (n=28) 6.5 Gy x 3 (n=28) 7 Gy x 3 (n=17) Median follow-up 33 m One patient grade 3 GU toxicity No patients with grade 3 GI toxicity 3-year bned 89% (Int-risk) and 78% (high-risk) UCSF experience 38 patients with minimum f/u of 12 months (median 18.3, ) 20 patients were treated CK monotherapy (9.5 Gy x 4) 18 patients were treated with EBRT (45-50Gy) CK boost (9.5Gy x 2) and 3-6 m of ADT. 44 HDR brachytherapy boost pts with PCa characteristics similar to the CK SBRT boost cohort was also analyzed as a descriptive comparison. Katz Tech Cancer Res 9:575, 2010 Jabbari IJROBP Dec, 2010 Page 6
7 CK for Prostate: UCSF experience No grade 3 or higher acute GU or GI toxicity. 2 patients (5%) with temporary late grade 3 GU toxicity No grade 3 late GI toxicity All pts are bned at last f/u CK monotherapy median f/u of 18.1 months median PSA nadir of 0.47 ng/ml ( ). CK boost median f/u of 23.5 m median PSA nadir of 0.1 ng/ml ( ) (post androgen recovery) HDR boost median f/u of 48.6 m median PSA nadir of 0.09 ng/ml ( ) Jabbari IJROBP Dec, 2010 Conclusion SBRT for prostate cancer compared to /protons: Allows for a shorter course of therapy For low α/β delivers higher BED Similarly well tolerated with low toxicity Similar biochemical control rates (>90%) at 5 years Allows for less rectum in low dose range compared to Allows for less bladder, femoral head and penile bulb dose SBRT for prostate cancer compared to brachytherapy: Dose distribution is similar to HDR brachytherapy Less invasive than brachytherapy Similar biochemical control rates (>90%) at 5 years When uses as a boost, produces similar PSA nadirs to HDR Page 7
Protons vs. CyberKnife. Protons vs. CyberKnife. Page 1 UC SF. What are. Alexander R. Gottschalk, M.D., Ph.D.
Protons vs. CyberKnife UC SF Protons vs. CyberKnife UC SF Alexander R. Gottschalk, M.D., Ph.D. Associate Professor and Director of the CyberKnife Radiosurgery Program Department of Radiation Oncology University
More informationCYBERKNIFE RADIOSURGERY FOR EARLY PROSTATE CANCER Rationale and Results. Alan Katz MD JD Flushing, NY USA
CYBERKNIFE RADIOSURGERY FOR EARLY PROSTATE CANCER Rationale and Results Alan Katz MD JD Flushing, NY USA Prostate Ablative Therapy Over the last 10 years our therapy has improved bned rates for LDR/HDR
More informationImplementation Date: April 2015 Clinical Operations
National Imaging Associates, Inc. Clinical guideline PROSTATE CANCER Original Date: March 2011 Page 1 of 5 Radiation Oncology Last Review Date: March 2015 Guideline Number: NIA_CG_124 Last Revised Date:
More informationRadiation Therapy for Prostate Cancer: Treatment options and future directions
Radiation Therapy for Prostate Cancer: Treatment options and future directions David Weksberg, M.D., Ph.D. PinnacleHealth Cancer Institute September 12, 2015 Radiation Therapy for Prostate Cancer: Treatment
More informationCyberknife Information Guide. Prostate Cancer Treatment
Cyberknife Information Guide Prostate Cancer Treatment CYBERKNIFE INFORMATION GUIDE PROSTATE CANCER TREATMENT As a patient recently diagnosed with localized prostate cancer, it is important that you familiarize
More informationClinical Trials and Radiation Treatment. Gerard Morton Odette Cancer Centre Sunnybrook Research Institute University of Toronto
Clinical Trials and Radiation Treatment Gerard Morton Odette Cancer Centre Sunnybrook Research Institute University of Toronto What I will cover.. A little about radiation treatment The clinical trials
More informationLATE MORBIDITY PROFILES IN PROSTATE CANCER PATIENTS TREATED TO 79 84 GY BY A SIMPLE FOUR-FIELD COPLANAR BEAM ARRANGEMENT
PII S0360-3016(02)03822-1 Int. J. Radiation Oncology Biol. Phys., Vol. 55, No. 1, pp. 71 77, 2003 Copyright 2003 Elsevier Science Inc. Printed in the USA. All rights reserved 0360-3016/03/$ see front matter
More informationParticle Therapy for Lung Cancer. Bradford Hoppe MD, MPH Assistant Professor University of Florida bhoppe@floridaproton.org
Particle Therapy for Lung Cancer Bradford Hoppe MD, MPH Assistant Professor University of Florida bhoppe@floridaproton.org Content Rationale for Particle Therapy in Lung Cancer Proof of Principle Treatment
More informationProton Therapy for Prostate Cancer
Proton Therapy for Prostate Cancer Andrew K. Lee, MD, MPH Director, Proton Therapy Center Associate Professor Department of Radiation Oncology M.D. Anderson Cancer Center Randomized studies showing benefit
More informationSubject: Proton Beam Therapy for Prostate Cancer
Subject: Proton Beam Therapy for Prostate Cancer Guidance Number: MCG-153 Revision Date(s): Original Effective Date: 10/30/13 Medical Coverage Guidance Approval Date: 10/30/13 PREFACE This Medical Guidance
More informationCorporate Medical Policy Intensity-Modulated Radiation Therapy (IMRT) of the Prostate
Corporate Medical Policy Intensity-Modulated Radiation Therapy (IMRT) of the Prostate File Name: Origination: Last CAP Review: Next CAP Review: Last Review: intensity_modulated_radiation_therapy_imrt_of_the_prostate
More informationCurrent and Future Trends in Proton Treatment of Prostate Cancer
Current and Future Trends in Proton Treatment of Prostate Cancer Reinhard W. Schulte Assistant Professor Department of Radiation Medicine Loma Linda University Medical Center Loma Linda, CA, USA Outline
More informationRadiation Therapy in Prostate Cancer Current Status and New Advances
Radiation Therapy in Prostate Cancer Current Status and New Advances Arno J. Mundt MD Professor and Chairman Dept Radiation Oncology Moores Cancer Center UCSD Radiation Therapy Wilhelm Roentgen (1845-1923)
More informationHow To Know If You Should Get A Brachytherapy Or Radioactive Seed Implantation
MEDICAL POLICY SUBJECT: BRACHYTHERAPY OR PAGE: 1 OF: 5 If the member's subscriber contract excludes coverage for a specific service it is not covered under that contract. In such cases, medical policy
More informationFAQ About Prostate Cancer Treatment and SpaceOAR System
FAQ About Prostate Cancer Treatment and SpaceOAR System P. 4 Prostate Cancer Background SpaceOAR Frequently Asked Questions (FAQ) 1. What is prostate cancer? The vast majority of prostate cancers develop
More informationRadiation therapy involves using many terms you may have never heard before. Below is a list of words you could hear during your treatment.
Dictionary Radiation therapy involves using many terms you may have never heard before. Below is a list of words you could hear during your treatment. Applicator A device used to hold a radioactive source
More information2/14/09. Long Term Risk of Radiation Therapy for Clinically Localized Prostate Cancer. Radiation Therapy: Various Forms of Radiation Treatment
Radical ctomy (surgery) Mack Roach III MD Professor & Chair Department of Radiation Oncology Long Term Risk of Radiation Therapy for Clinically Localized Cancer Radiation Therapy: Hormonal Therapy Cryotherapy
More informationFocal therapy for prostate cancer: seriously or seriously? Disclosures
Focal therapy for prostate cancer: seriously or seriously? Mitchell Kamrava, MD Assistant Clinical Professor Department of Radiation Oncology University of California Los Angeles Disclosures Speaking honorarium
More informationRadiation Therapy in Prostate Cancer Current Status and New Advances
Radiation Therapy in Prostate Cancer Current Status and New Advances Arno J. Mundt MD Professor and Chairman Dept Radiation Oncology Moores Cancer Center UCSD Presentation Welcome Overview of UCSD, Moores
More informationProstate Cancer Treatment: What s Best for You?
Prostate Cancer Treatment: What s Best for You? Prostate Cancer: Radiation Therapy Approaches I. Choices There is really a variety of options in prostate cancer management overall and in radiation therapy.
More informationAndre Konski, MD, MBA, MA, FACR Professor & Chair Department of Radiation Oncology Wayne State University School of Medicine Barbara Ann Karmanos
Andre Konski, MD, MBA, MA, FACR Professor & Chair Department of Radiation Oncology Wayne State University School of Medicine Barbara Ann Karmanos Cancer Center Financial None The views that I will be going
More information馬 偕 紀 念 醫 院 新 竹 分 院 前 列 腺 癌 放 射 治 療 指 引
馬 偕 紀 念 醫 院 新 竹 分 院 前 列 腺 癌 放 射 治 療 指 引 2009.12.02 修 訂 2013.05.13 四 版 前 言 新 竹 馬 偕 醫 院 放 射 腫 瘤 科 藉 由 跨 院 聯 合 會 議 機 制 進 行 討 論, 以 制 定 符 合 現 狀 之 前 列 腺 癌 放 射 治 療 指 引 本 院 前 列 腺 癌 放 射 治 療 指 引 的 建 立, 係 參 考 國 內
More informationPROTON THERAPY FOR PROSTATE CANCER: THE INITIAL LOMA LINDA UNIVERSITY EXPERIENCE
doi:10.1016/j.ijrobp.2003.10.011 Int. J. Radiation Oncology Biol. Phys., Vol. 59, No. 2, pp. 348 352, 2004 Copyright 2004 Elsevier Inc. Printed in the USA. All rights reserved 0360-3016/04/$ see front
More informationThe Science behind Proton Beam Therapy
The Science behind Proton Beam Therapy Anthony Zietman MD Shipley Professor of Radiation Oncology Massachusetts General Hospital Harvard Medical School Principles underlying Radiotherapy Radiation related
More informationBreast Cancer Accelerated Partial Breast Irradiation Bruce G. Haffty, MD Professor and Chairman Dept Radiation Oncology UMDNJ-RWJMS Cancer Institute
Breast Cancer Accelerated Partial Breast Irradiation Bruce G. Haffty, MD Professor and Chairman Dept Radiation Oncology UMDNJ-RWJMS Cancer Institute of New Jersey Rationale for Partial Breast Radiation
More informationDaily IGRT with CT-on-Rails Can Safely Reduce Planning Margin for Prostate Cancer: Implication for SBRT
Daily IGRT with CT-on-Rails Can Safely Reduce Planning Margin for Prostate Cancer: Implication for SBRT Wen Li, Andrew Vassil, Lama Mossolly, Qingyang Shang, Ping Xia Department of Radiation Oncology Why
More informationManagement of Postmenopausal Women with T1 ER+ Tumors: Options and Tradeoffs. Case Study. Surgery. Lumpectomy and Radiation
Management of Postmenopausal Women with T1 ER+ Tumors: Options and Tradeoffs Michael Alvarado, MD Associate Professor of Surgery University of California San Francisco Case Study 59 yo woman with new palpable
More informationTITLE: Comparison of the dosimetric planning of partial breast irradiation with and without the aid of 3D virtual reality simulation (VRS) software.
SAMPLE CLINICAL RESEARCH APPLICATION ABSTRACT: TITLE: Comparison of the dosimetric planning of partial breast irradiation with and without the aid of 3D virtual reality simulation (VRS) software. Hypothesis:
More informationNIA RADIATION ONCOLOGY CODING STANDARD. Dosimetry Planning
NIA RADIATION ONCOLOGY CODING STANDARD Dosimetry Planning CPT Codes: 77295, 77300, 77301, 77306, 77307, 77321, 77316, 77317, 77318, 77331, 77399 Original Date: April, 2011 Last Reviewed Date: November,
More informationProton Therapy for Prostate Cancer
BRADFORD HOPPE, MD, MPH 1 RANDAL HENDERSON, MD, MBA 1 WILLIAM M. MENDENHALL, MD 1 ROMAINE C. NICHOLS, MD 1 ZUOFENG LI, PhD 1 NANCY P. MENDENHALL, MD 1 Proton Therapy for Prostate Cancer Abstract: Proton
More informationTechnology PROSTATE CANCER. to diagnose, target and treat. US Too International 20 th Annual Symposium Chicago August 20-21, 2010 Michael Dattoli, MD
Technology to diagnose, target and treat PROSTATE CANCER US Too International 20 th Annual Symposium Chicago August 20-21, 2010 Michael Dattoli, MD It has been an Evolution Suspecting prostate cancer Detecting
More informationRT for High-Risk and Postoperative
RT for High-Risk and Postoperative Prostate Cancer ASTRO Refresher Course 2013 Stanley Liauw MD Associate Professor University of Chicago Dept of Radiation and Cellular Oncology Objectives Review evidence
More informationMichael J. Zelefsky,*, Heather Chan, Margie Hunt, Yoshiya Yamada, Alison M. Shippy and Howard Amols
Long-Term Outcome of High Dose Intensity Modulated Radiation Therapy for Patients With Clinically Localized Prostate Cancer Michael J. Zelefsky,*, Heather Chan, Margie Hunt, Yoshiya Yamada, Alison M. Shippy
More informationHow TARGIT Intra-operative Radiotherapy can help Older Patients with Breast cancer
How TARGIT Intra-operative Radiotherapy can help Older Patients with Breast cancer Jeffrey S Tobias, Jayant S Vaidya, Frederik Wenz and Michael Baum, University College Hospital, London, UK - on behalf
More informationProstate IMRT: Promises and Problems Chandra Burman, Ph.D. Memorial Sloan-Kettering Cancer Center, New York, NY 10021
Prostate IMRT: Promises and Problems Chandra Burman, Ph.D. Memorial Sloan-Kettering Cancer Center, New York, NY 10021 Introduction Prostate is one of the treatment sites that is well suited for IMRT. For
More information1 of 6 6/13/11 12:40 PM
ONCOLOGY. Vol. 25 No. 7 REVIEW ARTICLE Proton Therapy for Prostate Cancer By Bradford Hoppe, MD, MPH 1, Randal Henderson, MD, MBA 1, William M. Mendenhall, MD 1, Romaine C. Nichols, MD 1, Zuofeng Li, PhD
More informationPROSTATE CANCER WITH LARGE GLANDS TREATED WITH 3- DIMENSIONAL COMPUTERIZED TOMOGRAPHY GUIDED PARARECTAL BRACHYTHERAPY: UP TO 8 YEARS OF FOLLOWUP
0022-5347/03/1694-1331/0 Vol. 169, 1331 1336, April 2003 THE JOURNAL OF UROLOGY Printed in U.S.A. Copyright 2003 by AMERICAN UROLOGICAL ASSOCIATION DOI: 10.1097/01.ju.0000055773.91290.e8 PROSTATE CANCER
More informationProstate Cancer Guide. A resource to help answer your questions about prostate cancer
Prostate Cancer Guide A resource to help answer your questions about prostate cancer Thank you for downloading this guide to prostate cancer treatment. We know that all the information provided online
More informationFIVE-YEAR BIOCHEMICAL OUTCOME FOLLOWING PERMANENT INTERSTITIAL BRACHYTHERAPY FOR CLINICAL T1 T3 PROSTATE CANCER
PII S0360-3016(01)01594-2 Int. J. Radiation Oncology Biol. Phys., Vol. 51, No. 1, pp. 41 48, 2001 Copyright 2001 Elsevier Science Inc. Printed in the USA. All rights reserved 0360-3016/01/$ see front matter
More information1. Provide clinical training in radiation oncology physics within a structured clinical environment.
Medical Physics Residency Program Overview Our Physics Residency Training is a 2 year program typically beginning July 1 each year. The first year resident will work closely with medical physicists responsible
More informationStereotactic Radiotherapy for Prostate Cancer using CyberKnife
Stereotactic Radiotherapy for Prostate Cancer using CyberKnife Delivering the best in care UHB is a no smoking Trust To see all of our current patient information leaflets please visit www.uhb.nhs.uk/patient-information-leaflets.htm
More informationBaylor Radiosurgery Center
Radiosurgery Center Baylor Radiosurgery Center Sophisticated Radiosurgery for both Brain and Body University Medical Center at Dallas Radiosurgery Center 3500 Gaston Avenue Hoblitzelle Hospital, First
More informationRT for High-Risk and Post- operative Prostate Cancer ASTRO Refresher Course 2014
RT for High-Risk and Post- operative Prostate Cancer ASTRO Refresher Course 2014 Stanley Liauw MD Associate Professor University of Chicago Dept of Radiation and Cellular Oncology Objectives Review evidence
More informationStomach (Gastric) Cancer. Prof. M K Mahajan ACDT & RC Bathinda
Stomach (Gastric) Cancer Prof. M K Mahajan ACDT & RC Bathinda Gastric Cancer Role of Radiation Layers of the Stomach Mucosa Submucosa Muscularis Serosa Stomach and Regional Lymph Nodes Stomach and Regional
More informationAccelerated Partial Breast Irradiation (APBI) for Breast Cancer [Pre-authorization Required]
Accelerated Partial Breast Irradiation (APBI) for Breast Cancer [Pre-authorization Required] Medical Policy: MP-SU-01-11 Original Effective Date: February 24, 2011 Reviewed: February 24, 2012 Revised:
More informationForum. Advances in radiation therapy for prostate. cancer. Abstract. Radiation therapy for localised prostate. cancer
Advances in radiation therapy for prostate cancer Nitya Patanjali 1 and Scott Williams 2 1. Radiation Oncology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney. 2. Radiation Oncology, Peter
More informationPRIOR AUTHORIZATION Prior authorization is recommended and obtained via the online tool for participating providers.
Medical Coverage Policy Intensity-Modulated Radiotherapy of the Prostate EFFECTIVE DATE: 02 15 2016 POLICY LAST UPDATED: 03 23 2016 OVERVIEW Radiotherapy (RT) is an integral component in the treatment
More informationTransition from 2D to 3D Brachytherapy in Cervical Cancers: The Vienna Experience. Richard Pötter MD. BrachyNext, Miami, 2014.
Transition from 2D to 3D Brachytherapy in Cervical Cancers: The Vienna Experience Richard Pötter MD BrachyNext, Miami, 2014 Disclosures Richard Pötter, MD, does not have any financial relationships or
More informationIntroduction to Radiation Oncology
Editors: Abigail T. Berman, MD, University of Pennsylvania Jordan Kharofa, MD, Medical College of Wisconsin Introduction to Radiation Oncology What Every Medical Student Needs to Know Objectives Introduction
More informationintensity_modulated_radiation_therapy_imrt_of_abdomen_and_pelvis 11/2009 5/2016 5/2017 5/2016
Corporate Medical Policy Intensity Modulated Radiation Therapy (IMRT) of Abdomen File Name: Origination: Last CAP Review: Next CAP Review: Last Review: intensity_modulated_radiation_therapy_imrt_of_abdomen_and_pelvis
More informationPROTON BEAM THERAPY FOR PROSTATE CANCER. A Technology Assessment
PROTON BEAM THERAPY FOR PROSTATE CANCER A Technology Assessment INTRODUCTION The California Technology Assessment Forum is requested to review the scientific evidence for the use of proton therapy for
More informationEffective for dates of service on or after May 1, 2015 refer to: Blue Cross and Blue Shield of Alabama Radiation Therapy Management RTM Policies
Effective for dates of service on or after May 1, 2015 refer to: Blue Cross and Blue Shield of Alabama Radiation Therapy Management RTM Policies Name of Policy: Brachytherapy for Clinically Localized Prostate
More informationUnderstanding brachytherapy
Understanding brachytherapy Brachytherapy Cancer Treatment Legacy Cancer Institute Your health care provider has requested that you receive a type of radiation treatment called brachytherapy as part of
More informationThe Canadian National System for Incident Reporting in Radiation Treatment (NSIR-RT) Taxonomy March 2, 2015 V2
The Canadian National System for Incident Reporting in Radiation Treatment (NSIR-RT) Taxonomy March 2, 2015 V2 Taxonomy Data Category Number Description Data Fields and Menu Choices 1. Impact 1.1 Incident
More informationTechnology Assessment
Technology Assessment Technology Assessment Program Comparative evaluation of radiation treatments for clinically localized prostate cancer: an update Prepared for: Agency for Healthcare Research and Quality
More informationAccelerated Partial Breast Irradiation (APBI) for Breast Cancer
Accelerated Partial Breast Irradiation (APBI) for Breast Cancer [For the list of services and procedures that need preauthorization, please refer to www.mcs.pr Go to Comunicados a Proveedores, and click
More informationRadiation therapy is a well-established treatment option for patients with
Hematol Oncol Clin N Am 20 (2006) 857 878 HEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA Update on Radiation Therapy in Prostate Cancer Andrew K. Lee, MD, MPH*, Steven J. Frank, MD Division of Radiation
More informationBRACHYTHERAPY FOR TREATMENT OF BREAST CANCER
BRACHYTHERAPY FOR TREATMENT OF BREAST CANCER Coverage for services, procedures, medical devices and drugs are dependent upon benefit eligibility as outlined in the member's specific benefit plan. This
More informationBasic Radiation Therapy Terms
Basic Radiation Therapy Terms accelerated radiation: radiation schedule in which the total dose is given over a shorter period of time. (Compare to hyperfractionated radiation.) adjuvant therapy (add-joo-vunt):
More informationBRACHYTHERAPY OR CONFORMAL EXTERNAL RADIOTHERAPY FOR PROSTATE CANCER: A SINGLE-INSTITUTION MATCHED-PAIR ANALYSIS
doi:10.1016/j.ijrobp.2009.01.081 Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 1, pp. 43 49, 2010 Copyright Ó 2010 Elsevier Inc. Printed in the USA. All rights reserved 0360-3016/10/$ see front
More informationTreatment Volume and Technique
RADIATION THERAPY The standard of care for early lesions is surgical resection; however, selected patients with small central lesions may be considered for definitive radiation, particularly when the lesions
More informationHistorical Basis for Concern
Androgens After : Are We Ready? Mohit Khera, MD, MBA Assistant Professor of Urology Division of Male Reproductive Medicine and Surgery Scott Department of Urology Baylor College of Medicine Historical
More information02 CyberKnife: Treatment Delivery
TREATMENT DELIVERY CyberKnife Treatment Delivery System The CyberKnife System is the first and only robotic radiosurgery system to offer highly precise and customizable, non-surgical treatment options
More informationLong-term outcomes and prognostic factors in patients treated with intraoperatively planned prostate brachytherapy
Brachytherapy - (2012) - Long-term outcomes and prognostic factors in patients treated with intraoperatively planned prostate brachytherapy Carlos Vargas 1, *, Douglas Swartz 2, Apoorva Vashi 2, Mark Blasser
More informationPatient Guide. The precise answer for tackling cervical cancer. Brachytherapy: Because life is for living
Patient Guide Brachytherapy: The precise answer for tackling cervical cancer Because life is for living The aim of this booklet is to help women who have been diagnosed with cervical cancer and their family
More informationRe irradiation Using HDR Interstitial Brachytherapy for Locally Recurrent. Disclosure
Re irradiation Using HDR Interstitial Brachytherapy for Locally Recurrent Cervical lcancer Yasuo Yoshioka, MD Department of Radiation Oncology Osaka University Graduate School of Medicine Osaka, Japan
More informationThese rare variants often act aggressively and may respond differently to therapy than the more common prostate adenocarcinoma.
Prostate Cancer OVERVIEW Prostate cancer is the second most common cancer diagnosed among American men, accounting for nearly 200,000 new cancer cases in the United States each year. Greater than 65% of
More informationAmerican College of Radiology ACR Appropriateness Criteria DEFINITIVE EXTERNAL-BEAM IRRADIATION IN STAGE T1 AND T2 PROSTATE CANCER
American College of Radiology ACR Appropriateness Criteria Date of origin: 1996 Last review date: 2013 DEFINITIVE EXTERNAL-BEAM IRRADIATION IN STAGE T1 AND T2 PROSTATE CANCER Expert Panel on Radiation
More informationMedical Policy Brachytherapy for Clinically Localized Prostate Cancer Using Permanently Implanted Seeds
Medical Policy Brachytherapy for Clinically Localized Prostate Cancer Using Permanently Implanted Seeds Table of Contents Policy: Commercial Coding Information Information Pertaining to All Policies Policy:
More informationNeoadjuvant hormonal therapy in prostate cancer impact of PSA level before radiotherapy
JBUON 2013; 18(4): 949-953 ISSN: 1107-0625, online ISSN: 2241-6293 www.jbuon.com E-mail: editorial_office@jbuon.com ORIGINAL ARTICLE Neoadjuvant hormonal therapy in prostate cancer impact of PSA level
More informationDosimetry on the Intraoperative Procedure
LDR-Brachytherapy of Prostate Cancer: Impact of Post-Implant Dosimetry on the Intraoperative Procedure Dr. med. Armin Thöni Dr. phil. nat. Hans Neuenschwander PD Dr. med. Jörn Wulf Radio-Onkologie, Lindenhofspital
More informationProton Therapy for Prostate Cancer: Your Questions, Our Answers.
Proton Therapy for Prostate Cancer: Your Questions, Our Answers. When you re looking for the right treatment for your prostate cancer, nothing s more important than accurate information. Read on, and learn
More informationGamma Knife and Axesse Radiosurgery
Gamma Knife and Axesse Radiosurgery John C Flickinger MD Departments of Radiation Oncology & Neurological Surgery University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania Origin of Radiosurgery
More informationIBA Proton Therapy. Biomed days 2015. Vincent Bossier. System Architect Vincent.bossier@iba-group.com. Protect, Enhance and Save Lives
Vincent Bossier System Architect Vincent.bossier@iba-group.com IBA Proton Therapy Biomed days 2015 Protect, Enhance and Save Lives 1 Agenda AN INTRODUCTION TO IBA WHY PROTON THERAPY CLINICAL WORKFLOW TREATMENT
More informationDOCTOr. Doctor to HIGHLIGHTS. issue NO. 3 VOLuMe NO. 1
Doctor to DOCTOr issue NO. 3 VOLuMe NO. 1 PROSTATE CANCER is the most common cancer in men, with 233,000 new cases diagnosed per year. Although prostate cancer remains the second leading cause of cancer
More informationProstatectomy, pelvic lymphadenect. Med age 63 years Mean followup 53 months No other cancer related therapy before recurrence. Negative.
Adjuvante und Salvage Radiotherapie Ludwig Plasswilm Klinik für Radio-Onkologie, KSSG CANCER CONTROL WITH RADICAL PROSTATECTOMY ALONE IN 1,000 CONSECUTIVE PATIENTS 1983 1998 Clinical stage T1 and T2 Mean
More informationAmerican College of Radiology ACR Appropriateness Criteria HIGH-DOSE-RATE BRACHYTHERAPY FOR PROSTATE CANCER
Date of origin: 2013 American College of Radiology ACR Appropriateness Criteria HIGH-DOSE-RATE BRACHYTHERAPY FOR PROSTATE CANCER Expert Panel on Radiation Oncology Prostate: I-Chow Joe Hsu, MD 1 ; Yoshiya
More informationTable of Contents. Data Supplement 1: Summary of ASTRO Guideline Statements. Data Supplement 2: Definition of Terms
Definitive and Adjuvant Radiotherapy in Locally Advanced Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation
More informationONLINE CONTINUING EDUCATION ACTIVITY
ONLINE CONTINUING EDUCATION ACTIVITY Take free quizzes online at acsjournals.com/ce ARTICLE TITLE: Progress and Controversies: Radiation Therapy for Prostate Cancer CONTINUING MEDICAL EDUCATION ACCREDITATION
More informationWhat is the CyberKnife System?
CYBERKNIFE Robotic Radiosurgery System PATIENT BROChURE 1 What is the CyberKnife System? have stabilizing frames bolted to their head or limit their breathing during treatment to minimize movement of the
More informationCurrent Status and Future Direction of Proton Beam Therapy
Current Status and Future Direction of Proton Beam Therapy National Cancer Center Hospital East Division of Radiation Oncology and Particle Therapy Tetsuo Akimoto Comparison of status of particle therapy
More informationIGRT. IGRT can increase the accuracy by locating the target volume before and during the treatment.
DERYA ÇÖNE RADIOTHERAPY THERAPIST ACIBADEM KOZYATAGI HOSPITAL RADIATION ONCOLOGY DEPARTMENT IGRT IGRT (image-guided radiation therapy) is a technique that reduces geometric uncertainties by considering
More informationInnovative RT - Breast - APBI and Boost
Innovative RT - Breast - APBI and Boost The variables with REQ in superscript are required. The variables with a are single-select variables; only one answer can be selected. The variables with a are multi-select
More informationIEHP UM Subcommittee Approved Authorization Guidelines Proton Beam Radiation therapy for Prostate Cancer
Proton Beam Radiation therapy for Prostate Cancer Policy: The use of Proton Beam Therapy (PBT) in Prostate cancer has not been established as more effective than other forms of External Beam Radiation
More informationInnovative RT SBRT. The variables with REQ in superscript are required.
The variables with REQ in superscript are required. The variables with a are single-select variables; only one answer can be selected. The variables with a are multi-select variables; multiple answers
More informationPCa Commentary. Volume 73 January-February 2012 PSA AND TREATMENT DECISIONS:
1101 Madison Street Suite 1101 Seattle, WA 98104 P 206-215-2480 www.seattleprostate.com PCa Commentary Volume 73 January-February 2012 CONTENTS PSA SCREENING & BASIC SCIENCE PSA AND TREATMENT 1 DECISIONS
More informationOptimizing Adoption of Advanced Technology to Achieve High Value Cancer Care: The Case of Proton Therapy ECRI NCI Conference November 17, 2015
Optimizing Adoption of Advanced Technology to Achieve High Value Cancer Care: The Case of Proton Therapy ECRI NCI Conference November 17, 2015 Justin E. Bekelman, MD Associate Professor, Radiation Oncology
More informationProstate Cancer. Treatments as unique as you are
Prostate Cancer Treatments as unique as you are UCLA Prostate Cancer Program Prostate cancer is the second most common cancer among men. The UCLA Prostate Cancer Program brings together the elements essential
More informationClinical Education A comprehensive and specific training program. carry out effective treatments from day one
Proton Therapy Clinical Education A comprehensive and specific training program carry out effective treatments from day one Forewarned is forearmed Although over 100,000 patients have been treated in proton
More informationGated Radiotherapy for Lung Cancer
Gated Radiotherapy for Lung Cancer Steve B. Jiang, Ph.D. Depart Of Radiation Oncology University of California San Diego sbjiang@ucsd.edu radonc.ucsd.edu/research/cart Two Types of Gating Internal gating
More informationFunctional MRI (DCE-MRI) in the follow-up of prostate cancer after beam radiotherapy (EBRT)
Functional MRI (DCE-MRI) in the follow-up of prostate cancer after beam radiotherapy (EBRT) Poster No.: C-0748 Congress: ECR 2015 Type: Scientific Exhibit Authors: J. E. Méndez Escalante, D. Hernandez,
More informationThe optimal treatment for clinically localized
REVIEW COMBINING EXTERNAL BEAM RADIOTHERAPY WITH PROSTATE BRACHYTHERAPY: ISSUES AND RATIONALE CLARISSA FEBLES AND RICHARD K. VALICENTI The optimal treatment for clinically localized prostate cancer remains
More informationDetection and staging of recurrent prostate cancer is still one of the important clinical problems in prostate cancer. A rise in PSA or biochemical
Summary. 111 Detection and staging of recurrent prostate cancer is still one of the important clinical problems in prostate cancer. A rise in PSA or biochemical recurrence (BCR) is the first sign of recurrent
More informationQuality Assurance in Stereotactic. Radiotherapy
Quality Assurance in Stereotactic Radiosurgery and Fractionated Stereotactic Radiotherapy David Shepard, Ph.D. Swedish Cancer Institute Seattle, WA Timothy D. Solberg, Ph.D. University of Texas Southwestern
More informationNATURAL HISTORY OF CLINICALLY STAGED LOW- AND INTERMEDIATE-RISK PROSTATE CANCER TREATED WITH MONOTHERAPEUTIC PERMANENT INTERSTITIAL BRACHYTHERAPY
doi:1.116/j.ijrobp.9..1 Int. J. Radiation Oncology Biol. Phys., Vol. 76, No., pp. 349 354, 1 Copyright Ó 1 Elsevier Inc. Printed in the USA. All rights reserved 36-316/1/$ see front matter CLINICAL INVESTIGATION
More informationUse Of Testosterone In Men With Prostate Cancer. Traditional view: T is dangerous for PCa
Use Of Testosterone In Men With Prostate Cancer Abraham Morgentaler, MD, FACS Director, Men s s Health Boston Associate Clinical Professor of Urology Harvard Medical School Boston, USA Traditional view:
More informationAccreditation a tool to help reduce medical errors. Professor Arthur T Porter PC MD FACR FRCPC FACRO
Accreditation a tool to help reduce medical errors Professor Arthur T Porter PC MD FACR FRCPC FACRO Errors in Radiotherapy Radiation therapy is a highly regulated medical practice with historically low
More informationRobert Bristow MD PhD FRCPC
Robert Bristow MD PhD FRCPC Clinician-Scientist and Professor, Radiation Oncology and Medical Biophysics, University of Toronto and Ontario Cancer Institute/ (UHN) Head, PMH-CFCRI Prostate Cancer Research
More informationPOSICIONAMIENTO TECNOLOGICO Y CLINICO DE LA BRAQUITERAPIA FRENTE A LOS AVANCES DE LA ALTA TECNOLOGIA MODERNA
POSICIONAMIENTO TECNOLOGICO Y CLINICO DE LA BRAQUITERAPIA FRENTE A LOS AVANCES DE LA ALTA TECNOLOGIA MODERNA Alfredo Polo MD, PhD Brachytherapy & Intraoperative Radiotherapy Unit Ramon y Cajal University
More informationCorporate Medical Policy Brachytherapy Treatment of Breast Cancer
Corporate Medical Policy Brachytherapy Treatment of Breast Cancer File Name: Origination: Last CAP Review: Next CAP Review: Last Review: brachytherapy_treatment_of_breast_cancer 7/1996 5/2015 5/2016 5/2015
More information