April 29, Mayo School of Continuing Medical Education. Advances in Uro-Oncology: Eine Festschrift for Horst Zincke, M.D., Ph.D.

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1 Mayo School of Continuing Medical Education Advances in Uro-Oncology: Eine Festschrift for April 29, 2006 Geffen Auditorium, Gonda Building Rochester, Minnesota Course Description Advances in Uro-Oncology: Eine Festschrift for Horst Zincke, M.D., Ph.D., is an academic seminar designed to present the latest state-ofthe-art techniques and applications in the field of urologic oncology. Experts recognized around the world will be brought together for this program to share their knowledge. Didactic sessions, panel discussions, and case presentations are an integral part of the overall learning experience.

2 General Information Horst Zincke, M.D., Ph.D., was born in Frankfurt, Germany, and attended college and medical school at the Universities of Marburg/Lahn, Saarbrücken/Saar, Germany and Innsbruck, Austria, as well as at the University of Frankfurt am Main. He completed an internship and general surgery residency in Frankfurt and then accepted a year of internship in general surgery at the University of Iowa. Dr. Zincke then came to Mayo Clinic Rochester where he entered the general surgery program and subsequently completed his urology residency and became a Post-Graduate Fellow in Organ Transplantation and Research. He joined the Mayo Clinic staff in 1975 as a Consultant in Organ Transplantation (Department of Surgery) and the Department of Urology, becoming full Professor of Urology in Dr. Zincke s special interests have always been in uro-oncology. He established the Genitourinary Oncology Fellowship and was subsequently named head of the fellowship program accredited by the Society of Uro- Oncology at Mayo Clinic. He is a member of many regional, national, and international organizations and educational boards. He has been honored as Teacher of the Year in Urology three times and is in the Teacher of the Year Hall of Fame at Mayo Clinic. In 1993 he was awarded the named professorship Urology Professor in Honor of Dr. David C. Utz, which he held until 1994 when he spent 5 months at Health Care International Glasgow, United Kingdom, as Head of Uro-Oncology Surgery and Renal Transplantation Surgery. He has been a prolific writer with 400 publications in peer-reviewed journals and book chapters as well as over 500 abstracts, editorials, and letters to the editor. He has given hundreds of invited presentations, including multiple invited professorships in this country and throughout the world. Dr. Zincke has had a distinguished career as a master surgeon, clinician, research investigator, and teacher and has been the court of urological last resort for many difficult uro-oncology cases. Course Learning Objectives Discuss the criteria for renal preservation in patients with bilateral renal cell carcinoma. Review the detailed surgical anatomy and surgical techniques in patients with renal cell carcinoma with extension into the vena cava and right atrium. Gain an understanding of the current chemotherapeutic and immunologic adjuncts to management of advanced renal cell carcinoma. Discuss the complications of surgery in patients undergoing radical retropubic prostatectomy. Understand the application of radiation therapy for patients with prostatic adenocarcinoma. Review the continent urinary reservoirs available to patients undergoing extirpative surgery for bladder carcinoma. Understand the current management of patients with carcinoma in situ. Discuss which patients with testis cancer are candidates for retroperitoneal node dissection. Review the current options for BPH other than transurethral resection of the prostate. Attendance at this Mayo course does not indicate nor guarantee competence or proficiency in the performance of any procedures which may be discussed or taught in this course.

3 General Information Intended Audience Advances in Uro-Oncology is directed to urologists, oncologists, urogynecologists, and radiologists. Credit Mayo Clinic College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Mayo Clinic College of Medicine designates this educational activity for a maximum of 6 category 1 credits toward the AMA Physician s Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity. Non-US Licensed Physicians The American Medical Association has determined that non-us licensed physicians who participate in this CME activity are eligible for AMA PRA category 1 credit. Educational Grants This course is supported, in part, by educational grants in accordance with ACCME Standards. At the time of this printing, a complete listing of commercial supporters was not available. Appropriate acknowledgment will be given to all supporters at the time of the meeting. Date and Location Advances in Uro-Oncology will be held Saturday, April 29, Course headquarters will be located in Geffen Auditorium on the subway floor of the Gonda Building, Mayo Clinic, 100 Second Avenue Southwest, Rochester, Minnesota. Meeting facilities are easily accessible by skyway and pedestrian subway, which connect Mayo Clinic to shops, restaurants, and hotels. Registration To register, complete the attached registration form and return by mail or fax. The registration fee includes tuition, break refreshments, lunch, and dinner. Although it is not Mayo School of CME s policy to limit the number of registrants for a course, conference room facilities may necessitate closing of enrollment; therefore, early registration is advised. A letter of confirmation will be sent upon receipt of payment and completed registration form. Please present the confirmation letter when checking in at the meeting registration desk. Cancellation Policy If you cancel your participation in this course, your registration fee, less a $75 administrative fee, will be refunded when written notification is received by Mayo School of CME before April 14, 2006 (fax#: ). No refunds will be made after April 14, Mayo School of CME reserves the right to cancel or postpone any course due to unforeseen circumstances. In the unlikely event Mayo School of CME must cancel or postpone this course, Mayo School of CME will refund the registration fee, but is not responsible for any related costs, charges, or expenses to participants, including fees assessed by airline/travel/lodging agencies. Parking Parking is available in hotel, city, and Mayo patient/visitor ramps. The cost for parking is not included in the registration fee. A map indicating the location of downtown parking facilities will be mailed with the registrant confirmation letter.

4 General Information Travel Rochester, Minnesota, is a friendly city that greets thousands of visitors from around the world each year. The city is serviced by a modern international airport with multiple flights daily from Chicago, Detroit, Dallas-Fort Worth, and Minneapolis via American or Northwest Airlines. Access to and from the airport is provided by taxi, shuttle service, and rental car. The airport is located approximately 10 miles from the Mayo Clinic campus. Should you require a larger variety in flight options, there is shuttle service available from Minneapolis to Rochester. Minneapolis is approximately 70 miles north of Rochester. Rochester Direct, a local shuttle company, is located in the Kahler Hotel. Their schedule is available on Reservations are strongly encouraged. Note to Travelers: Several cities in the United States are named Rochester. When you make airline reservations and check your baggage, be sure that your destination is Rochester, Minnesota (RST), and that your baggage has been properly tagged. Travel arrangements are the sole responsibility of the individual registrant. Lodging Accommodations Guest rooms have been reserved for attendees and their guests with special course rates at the Rochester Marriott Hotel. In order to receive the special rate, reservations must be made before the room block is filled or before the expiration date of March 29, 2006, whichever comes first. Reservations will be taken following this date based on space and rate availability. Please identify yourself as a participant of the Advances in Uro-Oncology when making your reservation. Rochester Marriott Hotel 101 First Avenue SW or $105 single/double Several Rochester downtown hotels are connected by skyway and pedestrian subway to conference facilities, downtown shops, and restaurants. You may also wish to visit the Rochester Convention and Visitors Bureau website ( for additional accommodation options. Lodging arrangements are the sole responsibility of the individual registrant. Social Programs Eine Festschrift Dinner for Dr. Zincke Following the academic portion of the program, there will be a semiformal cocktail party with entertainment and sit-down dinner reception at the Kahler Hotel. This will include the attendees and their guests. Advance reservations are requested. Public tours of Mayo Clinic are provided each day of the week beginning at 10:00 am, except for holidays. The tours originate from Judd Auditorium, Subway Level of the Mayo Building, and last approximately 1.5 hours. The tour includes a 20-minute film on the history and operation of the Mayo Clinic plus visits to points of interest in the Mayo, Plummer, and Hilton Buildings. Please make advance reservations by calling Mall of America, the largest fully enclosed retail and family entertainment complex in the United States, is an easy 90-minute drive or shuttle ride from Rochester, Minnesota. Along with 500 retail stores, restaurants, and nightclubs, the mall features Knott s Camp Snoopy, the world s largest indoor theme park, and UnderWater World, a walk through an aquarium featuring 15,000 fish. Rochester Direct shuttle service will pick up at all local hotels and departs every two hours from 9:00 am 5:00 pm. The cost is $34 per person same day round trip. For reservations, call Rochester Direct at Check the shuttle schedule at their website:

5 Faculty Faculty MAYO CLINIC ROCHESTER Michael L. Blute, M.D. Anson L. Clark Professor of Urology Chair, Department of Urology Igor Frank, M.D. Senior Associate Consultant Matthew T. Gettman, M.D. Associate Professor of Urology Bradley C. Leibovich, M.D. Associate Professor of Urology Michael L. Lieber, M.D. Professor of Urology Robert P. Myers, M.D. Professor of Urology David C. Utz, M.D. Consultant, Emeritus, Professor of Urology, Emeritus Professor of Urology MAYO CLINIC SCOTTSDALE Paul E. Andrews, M.D. Associate Professor of Urology DISTINGUISHED GUEST FACULTY Peter C. Albertsen, M.D. Professor & Chief of Urology University of Connecticut Health Center, Farmington, Connecticut Christopher L. Amling, M.D. Professor and Director, Division of Urology University of Alabama at Birmingham, Birmingham, Alabama John Fitzpatrick, M.D. Professor & Chairman of Surgery Mater Misericordiae University Hospital and University College, Dublin, Ireland Richard S. Foster, M.D. Professor of Urology Indiana University Medical Center, Indianapolis, Indiana Inderbir S. Gill, M.D. Professor of Surgery Head, Section of Laparoscopic & Robotic Surgery Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio Harry W. Herr, M.D. Attending Urologist Memorial Sloan Kettering Cancer Center, New York, New York James E. Montie, M.D. Valassis Professor of Urologic Oncology Chair, Department of Urology, University of Michigan Medical Center, Ann Arbor, Michigan Andrew C. Novick, M.D. Professor of Surgery and Associate Dean for Faculty Affairs Cleveland Clinic Lerner College of Medicine Chairman, Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio J. Edson Pontes, M.D. Professor of Urologic Oncology, Assistant Dean of International Affairs Wayne State University, Detroit, Michigan Mark S. Soloway, M.D. Professor and Chairman, Department of Urology University of Miami Miller School of Medicine, Miami, Florida Faculty Disclosure As a provider accredited by ACCME, Mayo Clinic College of Medicine (Mayo School of CME) must ensure balance, independence, objectivity, and scientific rigor in its educational activities. Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of these relevant financial relationships will be published in course materials so those participants in the activity may formulate their own judgments regarding the presentation.

6 Program Schedule Saturday, April 29, :45 a.m. Welcome 9:00 a.m. Opening Comments Michael L. Blute, M.D. KIDNEY CANCER 9:00 a.m. The Evolution of Partial 9:20 a.m. Nephrectomy for Renal Cell Carcinoma Andrew C. Novick, M.D. 9:20 a.m. Diagnosis and Treatment 9:40 a.m. of Renal Cell Carcinoma: Lessons Learned From Dr. Horst Zincke Igor Frank, M.D. 9:40 a.m. Nephron-Sparing 10:00 a.m. Surgery: Minimally Invasive Experience in 800 Cases Inderbir S. Gill, M.D. 10:00 a.m. CASE PRESENTATIONS: 10:25 a.m. Moderator: Michael L. Blute, M.D. PROSTATE CANCER Andrew C. Novick, M.D. Igor Frank, M.D. Inderbir S. Gill, M.D. Comments: 10:25 a.m. Obesity and Prostate 10:45 a.m. Cancer Christopher L. Amling, M.D. 10:45 a.m. Salvage Surgery for 11:05 a.m. Radiation Failure J. Edson Pontes, M.D. 11:05 a.m. Why is PSA Screening 11:25 a.m. Still Controversial? Peter C. Albertsen, M.D. 11:25 a.m. CASE PRESENTATIONS: 11:50 a.m. Moderators: Michael L. Lieber, M.D. Robert P. Myers, M.D. Christopher L. Amling, M.D. J. Edson Pontes, M.D. Peter C. Albertsen, M.D. Comments: UROTHELIAL MALIGNANCIES 11:50 a.m. SIU Consultation on 12:10 p.m. Bladder Cancer Highlights From the Chairman Mark S. Solloway, M.D. 12:10 p.m. LUNCH BREAK 1:30 p.m. Bladder Cancer and 1:50 p.m. Quality of Care James E. Montie, M.D. 1:50 p.m. Optimal Therapy for 2:10 p.m. Invasive Bladder Carcinoma Harry W. Herr, M.D. 2:10 p.m. CASE PRESENTATIONS: 2:35 p.m. Moderator: Bradley C. Leibovich, M.D. Mark S. Solloway, M.D. James E. Montie, M.D. Harry W. Herr, M.D. Comments: TESTIS, LAPAROSCOPY, BPH 2:35 p.m. Technical Considerations 2:55 p.m. in Post Chemotherapy Testis Cancer Surgery Richard S. Foster, M.D. 2:55 p.m. Advances in Laparoscopy 3:15 p.m. for Urologic Malignancy Paul E. Andrews, M.D. 3:15 p.m. Advances in the Medical 3:35 p.m. and Minimally Invasive Management of BPH John Fitzpatrick, M.D. 3:35 p.m. CASE PRESENTATIONS: 4:00 p.m. Moderator: Matthew T. Gettman, M.D. Richard S. Foster, M.D. Paul E. Andrews, M.D. John Fitzpatrick, M.D. Comments: 4:00 p.m. 30 Years at Mayo Clinic: 4:15 p.m. Horst Zincke in Perspective David C. Utz, M.D. 4:15 p.m. ADJOURN

7 Registration Form Advances in Uro-Oncology: Eine Festschrift for April 29, 2006 Rochester, Minnesota Mail or FAX form with payment to: 2006R449 Mayo School of Continuing Medical Education Phone or Plummer 2-60 FAX First Street SW Rochester, MN Web site Contact Information Name of Registrant first name, middle name or initial, and last name Name of Institution Degree select all that apply MD DO PhD Other specify: Medical Specialty Work/Business Address street address Work Phone include all country and city/area codes as needed along with complete phone number City State or Province ZIP or Postal Code Country Home Address street address Home Phone include all country and city/area codes as needed along with complete phone number City State or Province ZIP or Postal Code Country Address FAX include all country and city/area codes as FAX Location select one needed along with complete phone number Work/Business Home SPECIAL NEEDS If you have special assistance needs or dietary restrictions, describe here: Registration Dinner Yes, I will be attending the dinner to honor Dr. Horst Zincke Complimentary Yes, I will be bringing a guest(s) Number of $60 $ Names of Guests Registration Fee Physician/Scientists: $350 $ Residents $265 $ Total $ Payment Information Check is enclosed in the amount shown at right make checks payable to Mayo Foundation Credit Card select one Account Number Exp Date mm/yy Discover MasterCard Visa Name of Cardholder as it appears on the card Signature of Cardholder required X Payment Total

8 200 First Street SW Rochester, Minnesota Non-Profit Organization U.S. POSTAGE PAID Minneapolis, MN Permit No Advances in Uro-Oncology: Eine Festschrift for Horst Zincke, M.D.,Ph.D. April 29, 2006 Geffen Auditorium, Gonda Building Rochester, Minnesota 2005, Mayo Press Printed in U.S.A. MC