Big Data in Toxicology: paradigm shift or hype?

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2 2nd Announcement Big Data in Toxicology: paradigm shift or hype? Join the 1st Joint meeting of the Dutch and Belgian Environmental Mutagen Society 24 November at Diergaarde Blijdorp in Rotterdam Dear colleague, It is our great pleasure to invite you to participate in the joint meeting of the Belgian and Dutch Environmental Mutagen Society. New technologies and data mining in (geno)toxicology are rapidly emerging in the 21th Century. These assays provide us with Big data on specific genes, pathways and molecular mechanisms. The question remains however how to interpret these data in the context of complex toxicological phenomena and multifactorial diseases. Hence, the handling of big data is partly based upon existing classical toxicity endpoints. The BEMS/DEMS 2016 meeting gathers academic, regulatory and industrial scientists. This year we especially invite young researchers in the field of product development, (bio)monitoring, medical and human/environment safety to present the latest output. During this meeting we will build a forum to discuss applied new techniques, share outcomes and provide support in the interpretation of the findings. We aim to connect traditional (eco)toxicological outcome and the data provided by newest technologies. Can we speak of a paradigm shift in human and environmental sciences enhancing the way we cope with resources and outcome of today s societal health and safety problems? We look forward to welcoming you in Rotterdam! Giel Hendriks DEMS chair Important dates: Lode Godderis BEMS chair Registration open: Abstract submission deadline: Early bird registration deadline: Registration deadline: 22th of August 21st of October 28th of October 16th of November

3 Preliminary Programme 9:00 10:00 REGISTRATION & COFFEE 10:00 10:10 Welcome & Introduction 10:10 10:50 Big Data in Health Care PART I: SETTING THE SCENE Chair: Lode Godderis KU Leuven 10:50 11:30 The Evolution of Safety Assessment 11:30 12:10 CRISPR/Cas9 and Next Generation Sequencing technology to study mutagenesis Lode Godderis (BEMS chair) Pieter Peeters Janssen (BE) Alan Boobis ICL (UK) Marcel Tijsterman LUMC Leiden (NL) 12:10 13:00 NETWORKING LUNCH + POSTER SESSION (ODD POSTER NUMBERS) PART II: PRESENTATIONS BY YOUNG RESEARCHERS 13:00 14:30 Oral presentation from PhD students (selected abstracts) 14:30 15:00 COFFEE BREAK + POSTER SESSION (EVEN POSTER NUMBERS) PART III: CASE STUDIES Chair: Giel Hendriks Toxys 15:00 15:40 Big Data Analysis of the complexity of a cardiac arrhythmia Brugada syndrome : a continuum from a mono over oligogenic inherited towards a multifactorial disease. 15:40 16:20 Research Institute for Asthma and COPD 16:20 17:00 Misconceptions in Toxicology can big data offer relief? 17:00 18:00 CLOSING REMARKS & RECEPTION Sonia Van Dooren UZ Brussel (BE) Cheng Xu UMCG (NL) Peter Boogaard Shell (NL) Giel Hendriks (DEMS chair)

4 Registration information You can register at the following link: Early bird registration Regular registration Late registration Before 28 th of October Before 16 th of November After 16 th of November and on site 70 euro 85 euro 100 euro Abstract submission You can upload your abstract during registration. Please use the following format foryour abstract: 1. Abstract length: no longer than 250 words (including titles and headings 2500 characters) 2. Text font: Times New Roman, 11 point font size, single line spacing, justified 3. Leave one line below the names and addresses and between paragraphs. Abstract submission deadline: 21st of October 2016 Presentations Poster presentations Posters should have the A0 size and should be made in the Portrait orientation. Please prepare a 1 2 minute poster presentation for the jury. Oral presentations PhD presentation Presenters are allotted a 5 minute total presentation time. There is a prize for the best oral presentation that will be awarded based on voting of the audience and a jury consisting of experts. Note: if you re not interested in giving an oral presentation, please note this during the abstract submission. The official format of the presentation is via data projector using Microsoft PowerPoint (Office 2010). Unfortunately, we do not support Prezi. All presenters must load and test their PowerPoint slides by 23 November

5 Awards During the award ceremony at the end of the day, the winners of the awards below will be announced. Best oral presentation Best PhD student poster Location and route Diergaarde Blijdorp Address: Blijdorplaan JG Rotterdam How to reach? Please visit the website: Questions If you have any questions, don t hesitate to contact us at belgian.dutch.ems@gmail.com or visit