MyRISQ. MultipleSclerosisRISQ. Taking Multiple Sclerosis into your own hands to control and manage the disease outcome.

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Claud Barton
7 years ago
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1 MyRISQ Taking Multiple Sclerosis into your own hands to control and manage the disease outcome.

2 What is Multiple Sclerosis (MS) Multiple sclerosis, also known as MS, is a chronic disease that attacks the central nervous system, i.e. the brain, spinal cord and optic nerves. Nerve fibers are surrounded by myelin, which protects them and helps conduct electrical signals - i.e. myelin facilitates a good flow of electricity along the nervous system from the brain. The myelin of a patient with MS becomes damaged in multiple areas. This leaves a scar (sclerosis). Therefore Multiple Sclerosis means Scar Tissue in Multiple Areas. The areas where there is either not enough or no myelin are called plaques or lesions. As these get worse the nerve fiber can break or become damaged. When a nerve fiber has less myelin the electrical impulses received from the brain do not flow smoothly to the target nerve - when there is no myelin the nerve fibers cannot conduct the electrical impulses at all. The electrical impulses are instructions from the brain to carry out actions, such as to move a muscle. With MS, your body does not respond to the instructions from your brain. What is Multiple sclerosis (MS) is caused by a complex interaction between genetic, infectious and environmental factors. In recent years genomic research has improved our understanding of the multifactorial nature of the disease. The - multiplex DNA test which analyses a combination of genetic variants in individuals previously diagnosed with multiple sclerosis was developed to empower patients with knowledge to better control and manage their disease outcome. results are interpreted in the context of blood tests, family history and lifestyle factors such as diet. represents another test in the line of MyRISQ pathology supported genetic tests.

3 To whom we recommend The test was developed for patients already diagnosed with multiple sclerosis who would like to take control of the disease process by learning about the effects of genetic variations and their interaction with environmental risk factors. Although genes cannot be changed, their effects in causing disease may be switched on or off by different lifestyle factors. tells you what you can do to decrease the risk factors for MS. Why request test The test cannot be used to diagnose MS. It doesn t tell you whether you will get MS or not. It provides information about how to improve your quality of life by enhancing myelin repair and maintenance, when viewed in the context of lifestyle factors that can be changed by the individual. Genetic differences among patients may also affect how certain drugs and nutrients are metabolised by the body. assesses genetic and lifestyle risk factors in relation to the metabolic profile of each patient, taking into account relevant gene-drug (pharmacogenetic) and gene-diet (nutrigenetic) interactions. It gives you information and guidance on how to improve myelin repair by managing lifestyle factors. Maintenance of myelin in turn leads to the improvement of quality of life. What is the result of the test going to tell me how will it help the doctor? This test facilitates the improvement of clinical management of MS as it offers molecular reclassification of patients into distinct treatment groups for individualised interventions. The test will provide you with a report that integrates genetics with the information on clinical indicators, family history and lifestyle. It includes detailed health guidelines as well as a personalised Nutrition Support Program. Your doctor may use the information from the test to decide on how to adjust the treatment. However, the lifestyle changes (e.g. diet, exercise) that may be required is mainly up to you. It is important that, after the test, you follow your doctor s recommendations.

4 How is MultipleSclerosisrisq different from other genetic tests on the market Where and how to request a test? (Pathology supported genetic testing) DTC (direct-to-consumer) genetic testing Your DNA analysed Integration of genetics and blood picture Analyses of interaction between genetics and nutrition Analyses of interaction between genetics and lifestyle Result is only computer generated* The result tells you the % of risk that you can get MS** Results of the test are interpreted by a doctor*** Beside saliva, information from questionnaire are needed * test result is partly computer generated. Result is reviewed and updated by a team of doctors. ** Due to the use of different data the results in % differ from one company to another. Therefore the results in percentages are irrelevant and even ethically controversial. *** Most providers of genetic tests do not offer proffesional medical consulting and interpretation of the results. For the test ask your doctor or write to us at info@myrisq.com. We will advise you where to perform the test. Security You submitt your saliva sample and fill in the questionnaire with the nurse. DiaGenomi ensures complete safety and anonymity of your data. 13-digit codes are used to mark questionnaires as well as the saliva samples. Since we Your saliva sample is sent to us for analyses together with the filled questionnaire. When the analyses is done the result of the test will be delivered to your doctor who will contact you for consulting. The doctor will explain the results and gives you guidelines how to proceed to control and manage your disease. do not receive any information from who the information and sample are, only 13-digit codes, your data and results are only known by you and your doctor.

5 Let us be part of your health! MyRISQ is a DiaGenomi product. info@diagenomi.eu

A Definition of Multiple Sclerosis

A Definition of Multiple Sclerosis English 182 READING PRACTICE by Alyx Meltzer, Spring 2009 Vocabulary Preview (see bolded, underlined words) gait: (n) a particular way of walking transient: (adj) temporary; synonym = transitory remission: