The 17 th Budapest Nephrology School (Nephrology, Hypertension, Dialysis, Transplantation)

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1 The 17 th Budapest Nephrology School (Nephrology, Hypertension, Dialysis, Transplantation) Under the auspices of ISN, ERA-EDTA and ISP August, 2010 In conjunction with the 8 th International Symposium on Wine and Health and on the occasion of the 5 th World Kidney Day Semmelweis University International Nephrology Research & Training Center Worldwide Hungarian Medical Academy Vanderbilt University Medical Center University of Toronto, Avicenna College Hungarian Kidney Foundation (Reg. Nr. 1987)

2 Faculty Peter Bárány, MD Associate Professor Dept of Renal Medicine Karolinska Universitetssjukhuset Stockholm, Sweden Tel: Fax: Ernő Péter Botos, MD Professor and Head Institute for Viticulture and Enology Corvinus University Úrihegy 5/A H-6000, Kecskemét Hungary Tel: Fax: Debbie Cohen, MD Renal, Electrolyte and Hypertension Division Department of Medicine University of Pennsylvania 1 Founders Building, 3400 Spruce Street, Philadelphia, PA U.S.A Tel: Fax: debbie.cohen@uphs.upenn.edu György Deák, MD, PhD Associate Professor Semmelweis University I. Department of Internal Medicine Korányi S. u. 2/a., 1083 Budapest, Hungary Tel: , Fax: deakgy@t-online.hu Marc E. De Broe, MD, PhD Professor of Medicine University of Antwerp Laboratory of Pathophysiology Universiteitsplein Wilrijk/Antwerpen, Belgium Tel: , Fax: marc.debroe@ua.ac.be Simin Goral, MD Associate Professor of Medicine University of Pennsylvania Medical Center 3400 Spruce street One Founders Philadelphia, PA, U.S.A. Tel: Fax: simin.goral@uphs.upenn.edu Ágnes Haris, MD, PhD Chief of Nephrology Section of St. Margit Hospital Bécsi út 132., 1032 Budapest, Hungary Tel: , Fax: agnesharis@hotmail.com J. Harold Helderman, MD Professor of Medicine, Microbiology and Immunology Assistant Dean, Vanderbilt University School of Medicine Vanderbilt University Medical Center 21st Avenue South Garland S-3223 Medical Center North Nashville, TN United States Tel: Fax: hal.helderman@vanderbilt.edu Béla Iványi, MD, DSc Professor of Pathology Department of Pathology Unversity of Szeged Állomás u. 2. H-6720 Szeged Hungary Tel: Fax: ivanyi@patho.szote.u-szeged.hu Jan T. Kielstein, MD, PhD, FASN Assistant Professor of Medicine Internist and Nephrologist Department of Nephrology Medical School Hannover Carl-Neuberg-Strasse Hannover Germany Tel: Fax: kielstein@yahoo.com István Kiss, MD, PhD, DSc Professor of Medicine Country s Chief Nephrologist Department of Gerontology Semmelweis University Department of Nephrology Tétényi út , 1115 Budapest, Hungary Tel: , Fax: ikiss@enternet.hu Csaba P Kovesdy, MD, FASN Chief of Nephrology Salem VA Medical Center 1970 Roanoke Blvd., Salem VA U.S.A Tel: x Fax: Csaba.Kovesdy@va.gov Róbert Langer, MD, PhD Associate Professor Chair of the Department of Transplantation and Surgery, Semmelweis University Baross u. 23. H-1082, Budapest Hungary Tel: /80150 Fax: langer@trans.sote.hu David C. Mendelssohn, MD, FRCPC Head, Department of Nephrology Humber River Regional Hospital and Professor of Medicine Division of Nephrology Department of Medicine University of Toronto Tel: Fax: DMendelssohn@hrrh.on.ca István Mucsi, MD, PhD Associate Professor Semmelweis University I. Department of Internal Medicine and Institute of Behavioral Sciences

3 Korányi S. u. 2/a. H-1083, Budapest Hungary Tel: Fax: Stefan Mustata, MD Assistant Professor University of Calgary, Canada Rockyview General Hospital th St. SW Calgary, Alberta, Canada T2V 1P9 Tel: Fax: Márta Novák, MD, PhD Associate Professor Semmelweis University Institute of Behavioural Sciences and Assistant Professor Dept. of Psychiatry, University of Toronto Nagyvárad tér 4., 1089 Budapest, Hungary Tel: , Fax: Rainer Oberbauer, MD, MSc KH Elisabethinen Linz & Medical University of Vienna, Austria T: F: c.at János Peti-Peterdi, MD, PhD Professor Zilkha Neurogenetic Institute Keck School of Medicine University of Southern California 1501 San Pablo st Los Angeles, California Tel: Fax: Eberhard Ritz, Dr. Dr. med. h.c. mult. FRCP(London und Edinburgh)FACP Immediate Past President of International Society of Nephrology (ISN) Professor of Medicine Dept. Internal Medicine Division Nephrology Im Neuenheimer Feld 162 D Heidelberg Germany Tel: +49 (0) or +49 (0) Fax: +49 (0) László Rosivall, MD, PHD, DSc Professor of Pathophysiology Hungarian Academy of Sciences and Semmelweis University Research Group for Pediatrics and Nephrology Institute of Pathophysiology Faculty of Medicine Semmelweis University, Budapest Nagyvárad tér 4. H-1089, Hungary Tel/Fax: Gerald Schulman, MD, FASN Professor of Medicine Co-Director of the Clinical Trials Center in Nephrology Vanderbilt University School of Medicine S-3223 Medical Center North Nashville, Tn USA Tel: Fax: Goce Spasovski, MD, PhD Associate professor Department of Nephrology Medical Faculty University of Skopje Vodnjanska Skopje Macedonia Balázs Szamosfalvi, MD Director, In-Patient Dialysis and CRRT Henry Ford Hospital 2799 W. Grand Blvd. Detroit, MI Tel: Fax: Mihály Tapolyai, MD Department of Nephrology Louisiana State University Health Science Center Shreveport 1501 Kings Highway Shreveport, LA, USA, Tel: Vladimir Tesar, MD Professor Division of Nehrology First Dep. Of Medicine U. Nemocnice 2 CZ Prague Czech Republic Tel: Fax: vladimir.tesar@lf1.cuni.cz Jens Titze, PD Dr. med. Department of Nephrology and Hypertension and Nikolaus-Fiebiger-Centre for Molecular Medicine Friedrich-Alexander-University Erlangen-Nuremberg Glückstr Erlangen Germany Tel: Fax: jtitze@molmed.uni-erlangen.de Tibor Tóth, MD, PhD Associate Professor Department of Cellular Pathology Southmead Hospital Bristol, UK, BS10 5NB Tel: Fax: Tibor.Toth@nbt.nhs.uk Tivadar Tulassay, MD, PhD, DSc Professor of Medicine President of the Semmelweis University Head of the I. Department of Pediatrics

4 Semmelweis University Bókay J. u. 53. H-1083 Budapest, Hungary Tel: Fax: Andrzej Wiecek, MD Professor Dept. of Nephrology, Endocrinology and Metabolic Diseases Silesian University School of Medicine Chief of Department: Prof. Dr hab Andrzej Wiecek Katowice, Francuska 20-24, Poland Tel: , Fax: Per Åke Zillén DDS and patient Kullstigen 13 SE Saltsjö-Boo Sweden Tel:

5 Dear Colleague, It is my pleasure to invite you to the 17th Budapest Nephrology School organized by the Hungarian Kidney Foundation at the Semmelweis University, under the auspices of ISN and ERA-EDTA in conjunction with the 8th International Symposium on Wine and Health and on the occasion of the 5th World Kidney Day. During this one-week program, our distinguished international speakers provide updates in nephrology, hypertension, dialysis and transplantation. We cover the field from molecule to bedside, from the most recent scientific advances to the current clinical approaches. You will also enjoy close interaction with the faculty in small group workshops. You are encouraged to present your poster, raise questions and consult your colleagues on problematic cases. You are also invited to visit our quality dialysis and research units. We have acted, based on the experience from previous successful years, to keep our standards high, invite internationally known speakers, provide the most optimal environment, encourage interaction and at the same time reduce the participation fee to the minimum. Our success is reflected by the increasing number of participants who have repeatedly attended the school. I hope that the commitment of my colleagues have successfully provided the best conditions for you to learn during this week. I also hope that you will enjoy our exciting social programs in Budapest. You should not forget about the 8th International Symposium on Wine and Health an important event where you will taste quality Hungarian wines. Wine is not only important to Hungarians but it has a several thousand-year history in mankind s life. Although, there are 22 historical vineyards in our country, among them such famous places as Tokaj, Villány, Badacsony, and the long culture and tradition of wine consumption, there is a high incidence of cardiovascular disease with the resultant serious decrease in life expectancy in this region. The 16th Budapest Nephrology School was accredited by the European Accreditation Council for Continuing Medical Education (EACCME) for 33 CME credits. The Course included 43 hours of scientific lectures and a final examination which can be locally evaluated according to national standards (in Hungary it is equal to 50 CME credits). We are expecting to have similar evaluation for the 17th Budapest Nephrology School as well. Sincerely yours, László Rosivall, MD, PhD, DSc President Semmelweis University, Faculty of Medicine Department of Pathophysiology International Nephrology Research & Training Center Website: rosivall@net.sote.hu

6 17th Budapest Nephrology School Program AUGUST 26 (THURSDAY) 08:00 09:00 REGISTRATION Venue: Department of Transplantation and Surgery Semmelweis University, Baross street , Budapest OPENING 09:00 09:45 Welcome Addresses and Official Opening 09:00 09:30 L. Rosivall, President of the Hungarian Kidney Foundation E. Ritz, Immediate Past President of the International Society of Nephrology A. Wiecek, European Renal Association European Dialysis and Transplant Association T. Tulassay, President of the Semmelweis University, Budapest I. Kiss, Hungary s Chief Nephrologist, President of Hungarian Society of Hypertension R. Langer, Chair of the Department of Transplantation and Surgery, Semmelweis University 09:30 09:45 Presentation of the 9th and 10th Silver Plate Awards of the Hungarian Kidney Foundation to Andrzej Wiecek (Poland) and János Peti-Peterdi (U.S.A) by the President KEYNOTE LECTURES 10:00 10:30 Kidney Health and Kidney Care Issues for the Individual and the Society Per Åke Zillen, Sweden 10:30-11:15 Reno-protection in Practice, a Doctor s and a Patient s Perspective. The Doctor: Here is the Evidence for your Reno-protective Treatment. The Patient: I take all your Pills, but where is my Treatment? 11:15 11:30 Discussion Peter Barany, Sweden BASIC SCIENCE 11:30 12:00 Intrarenal Renin Angiotensin Systems 12:00 12:15 Discussion János Peti-Peterdi, U.S.A 12:15 13:00 Lunch 13:00 13:30 Real-Time Imaging of Kidney Functions in Vivo 13:30 13:45 Discussion János Peti-Peterdi, U.S.A 13:45 14:15 New Findings in Sodium Balance 14:15 14:30 Discussion

7 Jens Titze, Germany 14:30 15:00 Genomics, Proteomics, Transcriptomics a Systems Biology Approach to CKD 15:00 15:15 Discussion Rainer Oberbauer, Austria 15:15 15:45 Coffee Break 15:45 16:15 Aldosterone Beyond Blood Pressure 16:15 16:30 Discussion Eberhard Ritz, Germany 16:30 17:00 Kidney Biopsy 17:00 17:15 Discussion Eberhard Ritz, Germany 18:00 22:00 8TH INTERNATIONAL SYMPOSIUM ON WINE AND HEALTH in conjunction with the 17th Budapest Nephrology School Hotel: Mercure Budapest Korona 1053 Budapest, Kecskeméti u :00 18:10 Presidential Greetings László Rosivall, Hungary 18:10 18:30 Cardiovascular Risk and Alcohol in General and Red Wine in Specific Eberhard Ritz, Germany 18:30 20:00 Elaboration and Presentation of the Hungarian Wines Ernő Péter Botos, Hungary 20:00 22:00 Dinner Special Hungarian Dishes Selected Quality Wines from the Best Known Hungarian Cellars AUGUST 27 (FRIDAY) HYPERTENSION 09:00 09:30 Hypertension and the Kidney 09:30 09:45 Discussion Eberhard Ritz, Germany 09:45 10:15 Hypertension Trials Update 10:15 10:30 Discussion Debbie Cohen, U.S.A 10:30 11:00 Coffee Break 11:00 11:30 Hypertensive Urgencies and Emergencies: Clinical Presentations and Therapy 11:30 11:45 Discussion Debbie Cohen, U.S.A 11:45 12:15 Role of the fat tissue in the pathogenesis of arterial hypertension and chronic kidney disease 12:15 12:30 Discussion Andrzej Wiecek, Poland

8 12:30 13:30 Lunch CLINICAL NEPHROLOGY 13:30 14:00 Primary Glomerular Disease 14:00 14:15 Discussion Vladimir Tesar, Czech Republic 14:15 14:45 Secondary Glomerular Diesease, Vasculitis Plasmapheresis Therapy 14:45 15:00 Discussion György Deák, Hungary 15:00 15:30 Coffee Break 15:30 16:00 Cardiovascular Risk Reduction in Kidney Transplant Recipients 16:00 16:15 Discussion Rainer Oberbauer, Austria 16:15 16:45 Update on Renal Anemia 16:45 17:00 Discussion Peter Barany, Sweden 17:00 17:45 Buffet 19:30 20:30 ORGAN CONCERT Venue: St. Stephen Basilica 1051 Budapest, St. Stephen square AUGUST 28 (SATURDAY) RENAL REPLACEMENT THERAPY 08:15 08:45 Evaluation of Kidney Transplant Recipients and Donor 08:45 09:00 Discussion Simin Goral, U.S.A 09:00 09:30 Pathology and Management of Chronic Allograft Dysfunction 09:30 09:45 Discussion Simin Goral, U.S.A 09:45 10:15 Immunobiology of Immunosuppression 10:15 10:30 Discussion J. Harold Helderman, U.S.A 10:30 11:00 Coffee Break 11:00 11:30 Complications in Hemodialysis 11:30 11:45 Discussion Gerald Schulman, U.S.A 11:45 12:15 Vascular Access 12:15 12:30 Discussion Gerald Schulman, U.S.A

9 12:30 13:00 HD Adequacy 13:00 13:15 Discussion Balázs Szamosfalvi, U.S.A 13:15 14:00 Lunch 14:00 18:00 SIGHTSEEING TOUR WITH PARLIAMENT VISIT 20:00 21:00 BOAT TOUR ON THE DANUBE AUGUST 29 (SUNDAY) DISTURBANCES IN CONTROL OF BODY FLUID VOLUME AND COMPOSITION 08:30 09:00 Pathophysiology of Water and Electrolyte Metabolism 09:00 09:15 Discussion Ágnes Haris, Hungary 09:15 09:45 Acid-Base Disorders, Acid-Base Quiz 09:45 10:00 Discussion Ágnes Haris, Hungary CHRONIC RENAL FAILURE 10:00 10:30 The Present and Future of Peritoneal Dialysis 10:30 10:45 Discussion Ágnes Haris,Hungary 10:45 11:15 Coffee Break 11:15 11:45 Exercise Rehabilitation - Its Role in the Management of Patients with CKD? 11:45 12:00 Discussion Stefan Mustata, Canada 12:00 12:30 Pregnancy and the Kidney 12:30 12:45 Discussion Stefan Mustata, Canada 12:45 13:45 Lunch 13:45 14:15 Effective Treatment Strategies to Delay the Progression of Renal Disease and Vascular Disease in CKD 14:15 14:30 Discussion Csaba P. Kovesdy, U.S.A 14:30 15:00 Secondary Hyperparathyroidism an Update on Pathophysiology and Treatment 15:00 15:15 Discussion Marc E. De Broe, Belgium 15:15 15:45 Coffee Break

10 15:45 16:15 Treatment Options for Chronic Kidney Disease: Metabolic Bone Disease 16:15 16:30 Discussion Goce Spasovski, Macedonia 16:30 17:00 Vitamin D and Survival in CKD and ESRD 17:00 17:15 Discussion Csaba P. Kovesdy, U.S.A. 17:15 17:45 Management of Iron Deficiency and Outcomes in CKD and ESRD 17:45 18:00 Discussion Csaba P. Kovesdy, U.S.A. 18:00 18:30 Buffet AUGUST 30 (MONDAY) Venue: B. Braun Avitum, Aesculap Academy 1115 Budapest, Halmi u (Transportation will be provided.) 09:00 09:30 Kidney-Pancreas, Pancreas Islet Transplantation Solutions for Diabetic Patients with Advanced CKD 09:30 09:45 Discussion Róbert Langer, Hungary 09:45 10:15 Continous Hemodialysis Modalities - Intensive Care Nephrology 10:15 10:30 Discussion Balázs Szamosfalvi, U.S.A 10:30 11:00 Coffee Break 11:00 11:30 Acute Kidney Injury 11:30 11:45 Discussion Jan T. Kielstein, Germany 11:45 12:15 Extracorporeal Treatments for Poisonings 12:15 12:30 Discussion Jan T. Kielstein, Germany 12:30 13:30 Lunch 13:30 14:00 Lessons from DOPPS 14:00 14:15 Discussion David Mendelssohn, Canada 14:15 14:45 Predialysis Care 14:45 15:00 Discussion David Mendelssohn, Canada 15:00 15:30 Coffee Break 15:30 16:00 Psychonephrology the Patient with Chronic Kidney Disease 16:00 16:15 Discussion Márta Novák, Canada

11 16:15 16:45 Sleep Disorders in Renal Patients 16:45 17:00 Discussion István Mucsi, Canada POSTER SESSION 17:00 19:00 Discussion with Wine 19:00 21:00 FAREWELL RECEPTION Sponsored by B.Braun Hungary LTD. AUGUST 31 (TUESDAY) PATHOLOGY 09:00 09:30 Renal Pathology 09:30 09:45 Discussion Tibor Tóth, United Kingdom 09:45 10:15 Renal Pathology Quiz 10:15 10:30 Discussion Tibor Tóth, United Kingdom 10:30 11:00 Coffee Break 11:00 11:30 Pathology of Kidney Allograft Dysfunction 11:30 11:45 Discussion Béla Iványi, Hungary 11:45 12:15 Interventional Nephrology 12:15 12:30 Discussion Mihály Tapolyai, U.S.A 12:30 13:15 EXAMINATION (Test) 13:15 14:00 Lunch 14:00 14:15 CONCLUDING REMARKS Commentary..., it is a pleasure for the International Society of Nephrology to recognize the tradition established by Dr. Rosivall and his colleagues in the heart of Europe, servicing so many colleagues in their quest for knowledge. Experts from various parts of the world have contributed to render the Budapest School into one of the best of its kind. We congratulate Dr. Rosivall on this momentous achievement. Jan J. Weening, Past President of ISN As a President of ERA-EDTA association I m very proud that our Society is a sponsor of the Budapest Nephrology School that next year will celebrate the 10th Anniversary. The best comment about the quality of this school come from a letter I received from one of the participants at last school "I was fortunate to be one of the sponsored delegate by the ERA. I do not have any words to express my sincere gratitude to the ERA and especially you for considering me for the grant from ERA. I do believe there are no other words to add!

12 Francesco Locatelli, Past President of ERA-EDTA The Semmelweis University under the dedicated leadership of Professor Rosivall has developed the tradition of an annual Nephrology Summer School in Budapest The panel of experts is impressive and has included some of the top leaders of nephrology in the world. In recognition of the high standard of this meeting, both the International Society of Nephrology (ISN) and the European Renal Association (ERA) co-sponsor this important event. Eberhard Ritz, President Elect of ISN Great work, worth to recommend to colleagues. A Participant Some faculty members of the previous Schools T. Andreoli, J. Balla, J. M. Bargman, C. Baylis, P.D. Bell, W. Van Biesen, R. Blantz, B. M. Brenner, M. E. De Broe, R. de Châtel, A. J. Collins, E. Cole, R. Coppo, W. G. Couser, A. Covic, P. Csermely, A. Davison, Gy. Deák, G. Devins, J. Dirks, T. B. Drücke, Cs. Dzsinich, K- U. Eckardt, A. Falus, J. Feehally, L. G. Fine, M. Fischereder, A. Fogo, D. Fouque, P. Gergely, D. Goldsmith, M. Goligorsky, S. Goral, J. G. Grunfeld, S. Halperin, Á. Haris, L. Harper, U. Heemann, A. Heidland, J. H. Helderman, G. Hercz, L. Hunyadi, E. J. Holtzman, A. Horváth, A. Iaina, N. Ismail, B. Iványi, K. J. Jager, J. Járay, V-M. Kahari, K. Kauser, D. Kerjaschki, J. T. Kielstein, I. Kiss, H. Klinkmann, E. Kolossváry, G. Kovacs, R. T. Krediet, K. Kurokawa, N. Lameire, S. Van Laecke, M. Little,G. M. London, A. Logan, N. Levin, F. Locatelli, F. Luft, A. MacLeod, O., Mehls, D. C. Mendelssohn, A. Meyrier, I. Mucsi, G. A. Müller, S. Mustata, J. Nagy, D. Naimark, M. Novák, K. Olgaard, H. H. Parving. M. Paul, F. Perner, J. Peti-Peterdi, R. Pisoni, A. Rees, P. Ronco, E. Ritz, L. Rosivall, B. Rutkowski,I. Rychlik, B. Sarkadi, D. Schlöndorff, H. Schmidt-Gayk, G. Schulman, E. Slatopolsky, S. Sonkodi, A. Spät,Z. Stevanovic, T. Szabó, B. Szamosfalvi, J. Titze, A. Tislér, S. W. Tobe, T. Tóth, T. Tulassay, S. Vas, P. Venetianer, J. J. Weening, A. Wiecek, I. Wittman, D. de Zeeuw, P.A. Zillén

13 17th Budapest Nephrology School In conjunction with the 8th International Symposium on Wine and Health and on the occasion of the 5th World Kidney Day August, 2010, Budapest Hungary Timetable at a glance Morning Thursday August 26 Registration 08:00-09:00 Official Opening 9:00-9:45 10:00-12:15 Friday August 27 09:00-12:30 Saturday August 28 08:15-13:15 Sunday August 29 08:30-12:45 Monday+ August 30 09:00-12:30 Tuesday August 31 09:00-12:30 Lunch 12:15-13:00 Lunch 12:30-13:30 Lunch 13:15-14:00 Lunch 12:45-13:45 Lunch 12:30-13:30 Examination 12:30-13:15 Lunch 13:15 14:00 Afternoon Evening 13:00-17:15 8th International Symposium on Wine and Health Venue: Mercure Budapest Korona 18:00-22:00 13:30-17:00 Buffet 17:00-17:45 Organ Concert St. Stephen Basilica 19:30 20:30 Sightseeing in Budapest 14:00-18:00 Boat Tour on the Danube 20:00-21:00 13:45-18:00 Buffet 18:00-18:30 Free Evening 13:30-17:00 Posters with Wine 17:00-19:00 Farewell Reception 19:00-21:00 Venue: Department of Transplantation and Surgery, Semmelweis University, 1082 Bp., Baross u Venue: B. Braun Avitum, Aesculap Academy, 1115 Budapest, Halmi u (Transportation will be provided.) Concluding 14:00 14:15

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