SYLLABUS. Introduction to Human Health Risk Assessment CPH 418/518 SWES 418/518.

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1 Time: Tuesday & Thursday, 12:30-1:45 pm Location: Drachman Hall, A114 SYLLABUS Introduction to Human Health Risk Assessment CPH 418/518 SWES 418/518 Instructor/Coordinator: Kelly A. Reynolds, MSPH, PhD Office: Drachman Hall, A231, Phone: (520) Other Lecturers: TBA GraduateTeaching assistants: Jonathan Sexton, MS, PhD Candidate Molly Scanlon, PhD Candidate Technical representative Lin Yi-Yeuh, MPH Candidate Office Hours: Dr. Reynolds: Tuesdays 8:30-10:30 or by appointment. The best way to get in touch with us is via . Please allow 48 hours for a response. Web Information: Readings, lecture slides, and other information relative to the course will be posted at The University of Arizona D2L (desire to learn) site, D2L.arizona.edu Be sure to check the site regularly for updated information. Course Description: Evaluation of environmental hazards and assessment of chemical and microbial exposures in various populations and the probability of associated health effects on the human population or the environment. Course Prerequisites: Undergraduates-advanced standing, Graduate Students-none (a background in science, engineering or math is helpful). Course Learning Objectives: At the end of this course, students will be able to: 1. Describe common, regulated, and emerging environmental contaminants and specific characteristics of each. 2. List the various health effects/toxic endpoints associated with hazard exposures in healthy and sensitive populations. 3. Identify primary and multiple exposure/transmission routes of environmental hazards. 4. Understand the steps involved in, and be able to perform, a qualitative and quantitative risk assessment. 5. Describe various approaches to risk analysis. 6. Differentiate the pros and cons of epidemiological vs. risk assessment studies. 7. Critique current research relative to methodological and statistical limitations and other assumptions or unknowns.

2 8. Evaluate the use of risk assessment for regulatory development or other mitigations. 9. Present the results of their risk assessment to the class. MPH Competencies Covered: ANALYTICAL SKILLS: Defines a problem Determines appropriate uses and limitations of data Selects and defines variables relevant to defined public health problems Evaluates the integrity and comparability of data and identifies gaps in data sources Understands how the data illuminates ethical, political, scientific, economic, and overall public health issues Understanding basic research designs used in public health Makes relevant inferences from data COMMUNICATION SKILLS: Communicates effectively both in writing and orally (unless a handicap precludes one of those forms of communication) Interpreting and presenting accurately and effectively demographic, statistical, and scientific information for professional and lay audiences adapting and translating public health concepts to individuals and communities Soliciting input from individuals and organizations Advocating and marketing for public health programs and resources, including political lobbying, grant writing, collaboration building, and networking Leading and participating in groups to address specific issues, including ability to work in teams, span organizational boundaries, and cross systems Using all types of media to communicate important public health information Demonstrating cultural competency in all of the above and community development POLICY DEVELOPMENT/PROGRAM PLANNING SKILLS: Assess and interpret information to develop relevant policy Identifying public health laws, regulations, and policies related to specific programs BASIC PUBLIC HEALTH SCIENCE SKILLS: Defining, assessing, and understanding the health status of population, determinants of health and illness, factors contributing to health promotion and disease prevention, and factors influencing the use of health services Understanding research methods in all basic public health sciences Applying the basic public health sciences including behavioral and social sciences, biostatistics, epidemiology, environmental public health, and prevention of chronic and infectious diseases and injuries Understanding of the historical development and structure of state. Local, and federal public health agencies CULTURAL SKILLS: Understanding the current forces contributing to cultural diversity in the Southwest Interacting competently, respectively, and professionally with persons from diverse backgrounds Identifying and examining the role of cultural, social, ethnic, religious, spiritual, and behavioral factors in determining disease prevention health promoting behavior, and health service

3 organizational and delivery Developing and adapting approaches to public health problems that take into account cultural differences Determining health related consequences of social structure Understands the dynamic forces contributing to cultural diversity FINANCIAL PLANNING AND MANAGEMENT SKILLS: Managing programs within budgetary constraints Developing strategies for determining priorities Applying the basic human relations skills to the management of organizations and the resolution of conflicts Managing personnel Conducts cost-effectiveness, cost benefit, and cost utility analyses Course Notes: You are expected to take your own notes in class. Students are responsible for collecting the material in class and for downloading information from the D2L website. Obtain notes from a fellow classmate if you are unable to attend class. Course Requirements: You are expected to attend class, respond to questions in class, participate in class discussions, submit the assignments on time and be prepared to discuss case studies or work through calculations in class, take the exams on the specified dates, collaborate effectively with your team on the team presentation and various assignments through the year, present your component of the team presentation, thoughtfully complete your self-evaluation, and complete any unscheduled quizzes given during scheduled classes. Grading/Student Evaluation: The grading system for this course is based on the following items: Homework assignments Midterm exam Class participation exercises Final presentation Final examination Total 125 pts 100 pts 50 pts 100 pts 100 pts 475 pts Final grades will be based on the following system: A = % B = 75-89% C = 65-74% E = < 65 Late assignments will be deducted 5% for every day late, including weekends. Graduate students will be expected to coordinate team tasks related to a quantitative risk characterization/assessment topic in class. In addition, graduate students will be expected to lead discussion teams throughout the semester for class participation points. Examinations: Students will be expected to demonstrate that they have met the course objectives through homework assignments and examinations. In class and final exams will consist of multiple choice, short answer and short essay questions. Some exams may include

4 self-evaluations or take-home questions. It is your responsibility to clear your calendar and take the exam at the scheduled time and place. Except for emergency situations (e.g., medical, supported by appropriate documentation), make-up exams or quizzes will not be given and zero credit will be awarded. You will lose points if you fail to show up for student presentations and team sessions. Class participation: points will be awarded based on participation in class discussions within the larger class and in assigned teams. The best way to ensure you receive the maximum participation points is to read and critique assigned literature, to come to class prepared to discuss the assigned reading, actively engage in team discussions, and attend all student presentations. Be able to show evidence of having completed and thought about the assigned readings (outline, discussion points, prepare questions prior to class) and participate in the discussion with others on your team. FINAL EXAM Wednesday May 8, 10:30 a.m. 12:30 p.m. Communications: You are responsible for reading s sent to your UA account from your professor and the announcements or D2L placed on the course web site. Information about readings, news events, your grades, assignments and other course related topics will be communicated to you with these electronic methods. The official policy can be found at: Disability Accommodation: If you anticipate issues related to the format or requirements of this course, please meet with me. I would like us to discuss ways to ensure your full participation in the course. If you determine that formal, disability-related accommodations are necessary, it is very important that you be registered with Disability Resources ( ; drc.arizona.edu) and notify me of your eligibility for reasonable accommodations. We can then plan how best to coordinate your accommodations. The official policy can be found at: Academic Integrity: All UA students are responsible for upholding the University of Arizona Code of Academic Integrity, available through the office of the Dean of Students and online: The official policy is found at: Students are required to write all answers to assignments and exams independently. Cases of cheating, or of helping others to cheat, will be penalized to the maximum extent allowed at the University. If you are uncertain about the difference between collaboration and copying, come see me. You are encouraged to discuss assignments but your answer must be written individually and represent your own understanding. Consequences for any type of academic misconduct may result in a grade of zero for assignment, or a failing grade for the course. Pay special attention to the sections on plagiarism. Plagiarism: What counts as plagiarism? Copying and pasting information from a web site or another source, and then revising it so that it sounds like your original idea. Doing an assignment/essay/take home test with a friend and then handing in separate assignments that contain the same ideas, language, phrases, etc. Quoting a passage without quotation marks or citations, so that it looks like your own.

5 Paraphrasing a passage without citing it, so that it looks like your own. Hiring another person to do your work for you, or purchasing a paper through any of the on- or off-line sources. Classroom Behavior: (Statement of expected behavior and respectful exchange of ideas) The Dean of Students has set up expected standards for student behaviors and has defined and identified what is disruptive and threatening behavior. This information is available at: Students are expected to be familiar with the UA Policy on Disruptive Behavior in an Instructional Setting found at and the Policy on Threatening Behavior by Students found at Grievance Policy: Should a student feel he or she has been treated unfairly, there are a number of resources available. With few exceptions, students should first attempt to resolve difficulties informally by bringing those concerns directly to the person responsible for the action, or with the student's graduate advisor, Assistant Dean for Student and Alumni Affairs, department head, or the immediate supervisor of the person responsible for the action. If the problem cannot be resolved informally, the student may file a formal grievance using the Graduate College Grievance Policy found at Grade Appeal Policy: Syllabus Changes: Information contained in the course syllabus, other than the grade and absence policies, may be subject to change with reasonable advance notice, as deemed appropriate. Telephone and Computer Use: You may use your computer in class for accessing course related content. Other uses of the computer during class are distracting to fellow students and lecturers and will not be permitted. Likewise, cell phones should be set to silent or vibrate in order to not disrupt the class and disturb your fellow students and professor. Course Schedule: Date General Topic Assignment Due January 12 Introduction, course scope, team dynamics January 17 Data sources; Risk Analysis January 19 Risk Assessment Paradigms; Hazard ID January 24 January 26 Toxicology; Ecological risk Homework 1 due- hazard ID January 31 Dose response February 2 February 7 Epidemiology/Decision making February 9 February 14 Homework 2 due- risk scenario February 16 Exposure Assessment February 21 Midterm review February 23 MIDTERM EXAM February 28 Risk characterization March 1 Analytical Approaches/ models/uncertainty Homework 3 due- calculations March 6 **Team management plan due

6 March 8 Case studies March 13 Spring Break- no class March 15 Spring Break- no class March 20 Risk Assessment Software/ Modeling March 22 March 27 Case studies Homework 4 due- presentation draft March 29 Precautionary approaches; Risk Management/regulatory controls April 3 Cost-benefit; Risk Communication Homework 5 due- modeling exercise April 10 Case studies, Future Considerations April 12 Student Presentations April 17 Student Presentations April 19 Student Presentations April 24 Student Presentations April 26 Student Presentations/ Course evaluations May 1 Final Exam Review Wednesday May 8, 10:30-12:30 pm Final Exam

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