Mosquitoes Ticks Chiggers Flies. Midges. Ants. Outdoor Malaria Transmission in Mekong Countries Meeting. Bangkok March 2013

Transcription

1 Mosquitoes Ticks Chiggers Flies Outdoor Malaria Transmission in Mekong Countries Meeting Midges Bangkok March 2013 Ants Copyright Insect Shield, LLC

2 Malaria Dengue Fever Insects can be dangerous. Yellow Fever Leishmaniasis Insect Shield reduces the risk. Sleeping Sickness Lyme Disease Copyright Insect Shield, LLC

3 What is Insect Shield? The active ingredient in Insect Shield products is permethrin. Insect Shield was granted the first-ever U.S. EPA registration of insect-repellent clothing in Insect Shield s current generation of technology allows for a longevity claim of through 70 launderings. Which is up to 35 times greater than a permethrin spray or dip method. ExxonMobil has approved its employees use of Insect Shield through 100 washes. Insect Shield technology can be applied to a wide variety of textile products from socks, hats, shirts, nets Copyright Insect Shield, LLC

4 Permethrin Treatment of Clothing is Recommended by Internationally Recognized Health Agencies The World Health Organization (WHO) The American Academy of Family Physicians The U.S. Department of Health & Human Services Centers for Disease Control and Prevention (CDC) The National Institute for Occupational Safety and Health (or NIOSH) The Public Health Agency of Canada Permethrin Treatment of clothing is widely recognized as beneficial in the battle against vector-borne diseases. Copyright Insect Shield, LLC

5 Insect Shield and the U.S. EPA The EPA s mission: to protect human health and the environment EPA review: Insect Shield s EPA registrations are based on rigorous review of efficacy and safety data produced using proven scientific methodology. A human bio-monitoring study done by Insect Shield further confirmed the safety judgment of the EPA. The patent-pending Insect Shield process is a 100% closed system, so no active ingredient is released into the environment during treatment. Copyright Insect Shield, LLC

6 Field study in Northern Kenya Use of insecticide-treated clothes for personal protection against malaria: a community trial (Kimani, E et al, 2006) Field study conducted in Dadaab, Northern Kenya and approved by ethical clearance board. Fundamental principles of ethics in studies with human participants were upheld throughout the study. A total of 198 participants were admitted to the study; 97 in the treatment group and 101 in the comparison group. Impregnation of personal clothes was done with permethrin for the treatment group and with water for the comparison group. Pre-test and post-test blood samples were taken. Results: the odds of malaria infection in the treatment group were reduced by 70% compared to the comparison group No side effects related to the use of impregnated clothing were observed with the participants during the study Copyright Insect Shield, LLC

7 Field study in Colombia Efficacy of Permethrin-Impregnated Uniforms in the prevention of malaria and Leishmaniasis in Colombian Soldiers (Soto, J et Al, 1995) Study conducted with the armed forces in malaria and leishmaniasis endemic areas in Colombia A total of 173 troops were admitted to the malaria study and 286 troops were admitted to the leishmaniasis study. 50% of the participants received permethrin impregnated shirt, undershirt, pants and socks; the remaining 50% received untreated clothing. Result: malaria infection in the treatment group was 75.5% lower than in the control group; leishmaniasis infection in the treatment group was 78 % lower than in the control group. Less than 1% of the individuals wearing permethrin impregnated uniforms reported irritation. Copyright Insect Shield, LLC

8 U.S. Army/U.S.D.A. research U.S. Army/U.S.D.A. research has quantified the effectiveness of permethrin-treated clothing for mosquito bite protection. Field study results show more than 97% reduction in bites, while wearing permethrin-treated clothing without additional repellent on exposed skin, at garment knockdown test rates of about 70%. 1 1 Schreck, Haile & Kline, The Effectiveness of Permethrin and DEET, Alone or in Combination, for Protection Against Aedes Taeniorhynchus, published in the American Journal of Tropical Medicine & Hygiene 33 (4): (1984). Copyright Insect Shield, LLC

9 Through Clothing

10 Exposed Skin

11 No Protection Total Bites

12 DEET Compared to Permethrin

13 % Knockdown in 60 Minutes Insect Shield Technology Longevity Comparison 100% 100% 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% 78% 55% 68% Total Protection Agricultural Permethrin Cold-dip Method 2 100% 62% Total Protection Agricultural Permethrin Using Insect Shield Process 4% Standard Agricultural Permethrin Treatment Versus Insect Shield Process Wash Test 1 100% 8% 100% 90% Number of Washes 86% 81% Total Protection Insect Shield Proprietary Chemistry and Process 0% 70% KD 84% 66% 70% All data for knockdown after one hour, aedes aegypti mosquitoes. Copyright Insect Shield, LLC

14 Target populations Public Health Work Wear Outdoor & Travel Military Copyright Insect Shield, LLC 2010

15 U.S. Army Permethrin Treatment Requirements The U.S. Army has recognized the importance of permethrin-treated military uniforms. All US Army uniforms are treated since ,000 active duty troops and 400,000 Army Reserve troops are wearing treated uniforms. Insect Shield has treated millions of uniforms for the US Army and other branches of the military. Copyright Insect Shield, LLC

16 Army Insect Shield s first military customer was West Pint Military Academy, which has contracted with Insect Shield every year for over 10 years. Insect Shield treats hundreds of thousands of uniforms for the US Army and US Marine Corp each year. Insect Shield works both as a prime contractor (working directly with the Army) and as a subcontractor (working with uniform manufacturers). Copyright Insect Shield, LLC 2010

17 Consumer Products Insect Shield licenses brands to use the technology within their clothing lines. Over 33 current brand partners including Orvis, Outdoor Research, REI, Ex Officio and Columbia Sportswear (under Insect Blocker brand) Categories cover clothing, pet products, horse products, camouflage and gear (such as hammocks, chairs and shelters) Copyright Insect Shield, LLC 2010

18 Work Wear Malaria and Neglected Tropical Diseases have a significant negative impact on business: Increase absenteeism Reduce productivity at work Increase healthcare spending Negative impact on corporate reputation Insect Shield has created a line of work clothes to meet the needs of large industrial end users. These users often are sending workers to places where malaria and other tropical insect borne diseases are endemic. Customers include ExxonMobil, Chevron, Schlumberger, Anadarko Petroleum, Newmont Mining and Weyerhaeuser. Copyright Insect Shield, LLC 2010

19 Permethrin-treated clothing for Public Health use Do not require behavior changes 70 washes: no need for frequent reapplication (Vs topical repellent) Situations where the traditional methods of IRS and LLINs are not sufficiently effective General population in case of early biting vectors People sleeping outdoor Neglected Tropical Diseases transmitted during daytime Copyright Insect Shield, LLC 2010

20 Permethrin-treated clothing for Public Health use Forest workers, populations working on plantations (e.g. palm oil plantations) or farms on forest fringes Copyright Insect Shield, LLC 2010

21 Permethrin-treated clothing and blankets Communities where people are displaced by disasters or poverty Copyright Insect Shield, LLC 2010

22 Public Health Insect Shield blanket is being launched Summer Trial on dengue Fever ongoing in primary schools in Thailand being led by researchers at Umea University in Sweden and cocollaborators from London School of Tropical Medicine being carried out in the Muang District in Thailand, near the Thai/Myanmar border. Trial on sleeping sickness (phase 1) led by researchers at London School of Tropical Medicine. the first phase: knockdown testing of Insect Shield products against Tsetse flies (Zimbabwe). Copyright Insect Shield, LLC 2010

23 Thank you for your attention Insect Shield, LLC 814 West Market Street Greensboro, NC phone fax Copyright Insect Shield, LLC