Contained Materials Handling for the Pharmaceutical Industry. engineering for a better world
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1 Contained Materials Handling for the Pharmaceutical Industry engineering for a better world
2 GEA Group is a global specialist in solid and liquid dose technology. Combining trusted technology with an ongoing programme of innovation and price/performance leadership, GEA has a long history of expertise and an unparalleled depth of experience in the fields of batch and continuous granulation, drying, pelletizing and coating, contained materials handling, tablet compression, pharmaceutical freeze drying, fermentation and liquid formulation, separation, homogenization and cell disruption. With manufacturing and technology centres all over the world, GEA provides the services that the pharmaceutical industry needs, including technical know-how, test facilities for product development and process evaluation, project management, market-leading equipment, customer service and support. Working closely with its customers to develop new products, reduce time to market and enhance clinical effectiveness, GEA s scope of supply ranges from R&D-scale and standalone production equipment to the installation of completely integrated production lines and continuous processing technology. GEA is your single-source supplier of robust, flexible and cost-effective pharmaceutical manufacturing solutions that maximise operational reliability and productivity.
3 Contained pharmaceutical powder handling GEA is the market-leading specialist for the supply of contained and integrated materials handling solutions to the pharmaceutical and healthcare industries worldwide. With an individual approach to each customer s needs, extensive experience and know-how, we deliver excellence and technological innovation for our customers long-term competitive advantage. System Integration Our distinctive specialisation lies in the integration of the GEA containment technology into complete solutions for pharmaceutical solid dosage forms facilities. With an emphasis on quality and GMP standards, we are committed to working together with our customers to deliver first class tailored solutions for projects of all sizes and complexity. Containment and powder technology Through the use of BUCK Valve technologies, we provide a dust-free highly contained powder transfer. Our systematic approach to design eliminates contamination and leakage of material throughout the process line whilst still maintaining flexibility for either CIP or COP, and meets the strictest GMP requirements in the industry. We offer a complete range of quality Intermediate Bulk Containers (IBCs), used for processing, storage, blending and transportation of pharmaceutical products, including excipients, active powders, granules, capsules and tablets, from dispensing through to feeding packaging systems. Dispensing Our systems optimise this operation, which is vital to a solid dosage pharmaceutical process. We provide a modular range of manual and automated weighing equipment, creating bespoke systems designed to optimise the weighing and dispensing of raw materials. With software solutions to provide complete recipe management, process and weight control, material traceability and process repeatability, together with weighing, handling and containment equipment, each dispensary system is individually tailored to the meet clients process requirements and fit in with the building design. Discharging and Filling IBC s For difficult flowing materials, products subject to segregation and damage, and the need to transfer potent products in a contained manner, we provide unique technologies for accurate filling and discharging. These ensure high levels of containment, rapid product change over, Cleaning In Place (CIP) and complete discharge with no segregation. Blending Our extensive process knowledge and continuous research delivers the most efficient blending process. We offer a wide range of technical solutions and process options to ensure efficient mixing and blending of powders and granules. Washing A full range of washing solutions are available for contained cleaning of active charge vessels, containers and IBCs. In addition, mobile CIP units offer an alternative for use at key stages within the process. We also offer wash solution preparation systems and process control solutions to allow full validation of the washing system.
4 Enhancing production performance Dispensing: Modular designs High containment Weigh dispensing Bulk dispensing Recipe management Batch tracking Complete process control Granulation: Single or multi level configuration Powder discharge solutions - Vibroflow BUCK Containment Valves Cleaning in Place (CIP) Inline milling Vacuum transfer Contained charge vessels
5 Integrated Powder Handling Solutions Milling: Dust-free/contained interfacing Hoist mounted systems Cleaning in Place (CIP) Blending: Fully contained processes High efficiency blending - Prism Direct compression/dry blending Contained powder additions Through wall solutions Hoist and pedestal blenders R&D to production Washing: Mobile CIP/WIP units Clean off place designs Automated container washing systems Halo wash technology Compression and Coating: Single or multi level solutions Desegregation - Decelerator / Vibroflow BUCK Containment Valves Area separation/isolation Rapid product change over Clean In/Off Place (CIP/COP) Tablet Handling: Tablet/capsule IBCs and Tablet Bags Avoid tablet damage - decelerators Hoist and lifters Tablet valves and chutes Tablet containment solutions advancing the working environment
6 We live our values. Excellence Passion Integrity Responsibility GEA-versity GEA Group is a global engineering company with multi-billion euro sales and operations in more than 50 countries. Founded in 1881, the company is one of the largest providers of innovative equipment and process technology. GEA Group is listed in the STOXX Europe 600 index. GEA Pharma Systems GEA Process Engineering Ltd PO Box 15, Eastleigh, Hampshire, SO53 4ZD, United Kingdom Tel: pharma@gea.com gea.com GEA Group 2015 (Pharma). Specifications subject to change without notice. All trademarks recognised. All copyrights reserved. Under no circumstances should this document or any part of it be copied without written consent.
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