University of Windsor Program Development Committee

Transcription

1 University of Windsor Program Development Committee PDC a 5.7.1a: Item for: Master of Medical Biotechnology New Course Proposals Approval MOTION: That the following course additions be made*: Protein Structure and Function Proteomics and Biological Mass Spectrometry Drugs: From Discovery to Market Clinical Biochemistry Biochemistry and Cell Biology of Lipids and Membranes Human Physiology and Mechanisms of Disease Biotechnology Laboratory Biotechnology Entrepreneurship *Subject to approval of the expenditures required. Approvals: The proposal has been approved by the Department of Chemistry and Biochemistry Council, Faculty of Science Council and the Faculty of Graduate Studies Coordinating Council (April 24, 2012). See attached.

2 TITLE OF THE PROGRAM/CERTIFICATE: DEPARTMENT/SCHOOL: FACULTY: Proposed change(s) effective as of: NEW COURSE PROFILE Course # and Title: Protein Structure and Function Master of Medical Biotechnology Chemistry & Biochemistry Science Calendar Description Calendar descriptions should be written in the third person and should provide a general outline of the course material. Where appropriate, examples of topics or themes, which might be covered in the course, should also be provided. This course will review and examine the principles of protein structure and how it applies to protein function. Moreover, how protein function is controlled and functional genomics will also be considered. Methodologies used in protein structure determination will also be highlighted. The laboratory section of the course will focus on web based computational programs as they apply to protein structure. Other Course Information Please complete the following tables. Credit weight Total contact hours In-class e- learning Delivery format Distanc e Other flexible learning delivery [please specify] Breakdown of contact hours/week Lecture Tutorial Lab. Co-op/ practicum 1 36 X 1.5h/wk 1.5h/ wk the MMB program. Prerequisites Corequisites Antirequisites Registration restricted to those enrolled in Crosslisted with: Required course X Optional course Replacing old course*** [provide old course number] ***Replacing Old Course (this does not mean that the former course will be deleted from the calendar. If it is to be deleted, a Form E must be completed.) Will students be able to obtain credit for the new course and the course(s) that it is replacing? Not applicable. B. RATIONALE B.1 Course Goal(s) Please provide a statement about the purpose of the course within the program of study or as an option. Any student pursuing molecular biotechnology must have a fundamental understanding of the principles of protein structure which is related to both protein function and drug design. This course will provide students with the appropriate required background.

3 B.2 LEARNING OUTCOMES (QAF section 2.1.1, 2.1.3, and 2.1.6) Please complete the following table. State the specific learning outcomes that make up the goal of the course (what will students know and be able to do at the end of this course?) and link the learning outcomes to the Characteristics of a University of Windsor Graduate outlined in To Greater Heights by listing them in the appropriate rows. Please note that a learning outcome may link to more than one of the specified Characteristics of a University of Windsor Graduate, and that a single course may not touch on each of the Characteristics. Each University of Windsor program should produce graduates that are able to demonstrate each of the nine characteristics approved in To Greater Heights. Information on learning outcomes is appended to this form (Appendix A). The information is also on the PDC Website or through the University Secretariat. Proposers are also strongly encouraged to contact the Office of the Vice-Provost, Teaching and Learning for assistance with the articulation of learning outcomes. Learning Outcomes (see Appendix A for more on learning outcomes) At the end of this course, the successful student will know and be able to: discuss how protein structure is related to protein function. apply knowledge of protein-structure relationships to predict the function of a protein or vice versa. use the Protein Databank (PDB) to obtain information on protein structure. appraise currently published scientific references, and determine protocols for potential future studies. write scientific reports on how the structures of proteins are related to diseased states. work independently. Characteristics of a University of Windsor Graduate A U of Windsor graduate will have the ability to demonstrate: A. the acquisition, application and integration of knowledge B. research skills, including the ability to define problems and access, retrieve and evaluate information (information literacy) C. critical thinking and problem-solving skills D. literacy and numeracy skills E. responsible behaviour to self, others and society present findings regarding the relationship between protein structure and the diseased state. work together well as part of a team with their peers in laboratory exercises. F. interpersonal and communications skills G. teamwork, and personal and group leadership skills H. creativity and aesthetic appreciation know protein structure relationships and assess how they relate to other diseased states. I. the ability and desire for continuous learning

4 B.3 Demand for Course Please provide as much information on projected enrolment as possible. Projected enrolment levels for the first 5 years of the new course. Year 1 Year 2 Year 3 Year 4 Year What will be the impact of offering the new course on enrolments in existing courses in the program or Department? As this course is specifically designed for utilization within the Master of Medical Biotechnology (MMB) program, which is a course-based, cohort-managed professional graduate degree, we do not foresee any impact on existing courses in the program or Department by offering this new course. B.4 Student Workload Provide information on the expected workload per week of a student enrolled in this course. NOTE: Student workload should be consistent with the credit weight assigned to the course. Average number of hours per week that the student will be expected to devote to: 1.5 Lectures Tutorials 1.5 Labs Practical experience Independent Study 2.5 Reading for the course 2.5 Work for assessment (essays, papers, projects, laboratory work) Meeting with others for group work/project assignments 2 Studying for tests/examinations Other: [specify] How does the student workload for this course compare with other similar courses in the department/program area?the workload is comparable to other courses. C. RESOURCES C.1 Available Faculty and Staff Resources (QAF sections 2.1.7, 2.1.8, and ) Describe all faculty and staff resources (e.g., administrative, teaching, supervision) from all affected areas/departments currently available and actively committed to support the new course. All of the faculty identified are currently or have been actively involved in graduate student supervision and notably, have extensive experience in supervising and instructing international graduate students from a diverse range of cultural and educational backgrounds. Furthermore, all of the above are actively involved in the academic activities of the department including seminars, conferences, etc. As it is a course-based Masters, no research supervision will be required. The instructors will be responsible to the MMB students within their specific graduate course for office hours, feedback, etc. They will be assisted in their duties by the 'Biotech. Coordinator' who will assist instructors with some general duties such as course assessment design and implementation for the MMB students, and tabulation and coordination of their grades.

5 C.1.1 Provide an assessment of faculty expertise available and committed to actively support the new course. Prof. Lana Lee research interests lie in the field of NMR determination of protein structures as a means of elucidating both how proteins construct their complex 3D shapes, and how this relates to their function. In addition, she has won a University award for her mentoring of students. C.1.2 Describe the area s expected reliance on, and the role of adjunct, limited-term, and sessional faculty in delivering the new course. It is expected that our tenured faculty, within the Department of Chemistry and Biochemistry, would deliver this course. If not, faculty from collaborating academic units and/or collaborating institutions would be drawn upon to meet the high level expertise required within this discipline. The Centre for Executive and Professional Education would assist in the recruitment of qualified applicants from government, academia, or industry. C.2 Resource Implications for Other Campus Units (MTCU sections 3 and 4) Describe the reliance of the proposed new course on existing resources from other campus units, including for example: faculty teaching, equipment or facilities outside the proposer s control, external resources requiring maintenance or upgrading using external resources Provide relevant details. None C.3 Anticipated New Resources (QAF sections 2.1.7, and 2.1.9; MTCU section 4) List all anticipated new resources originating from within the area, department or faculty (external grants, donations, government grants, etc.) and committed to supporting the revisions to this program. None C.4 Planned Reallocation of Resources and Cost-Savings (QAF section and 2.1.9; MTCU section 4) Identify all opportunities for internal reallocation of resources and cost savings identified and pursued by the area/department in support of the new course. (e.g., streamlining existing programs and courses, deleting courses, etc.)? This proposed course is part of the Faculty of Science / Department of Chemistry and Biochemistry s Master of Medical Biotechnology program. There is no planned reallocation of resources or cost-savings identified; however, this course is part of a cost recovery program and thereby will not place any additional pressure on existing programs or courses. C.5 Additional Resources Required Resources Requested (QAF section and 2.1.9) Describe all additional faculty, staff and GA/TA resources (in all affected areas and departments) required to offer the new course. Faculty: There are no additional faculty resources that will be needed related to the teaching of this course. Staff: There are no additional staff resources that will be needed related to the teaching of this course. GA/TAs: There are no additional GA/TA resources that will be needed related to the teaching of this course.

6 C.5.1 Describe all additional institutional resources and services required by all affected areas or departments to offer the new course, including library, teaching and learning support services, student support services, space and facilities, and equipment and its maintenance. Library Resources and Services: There is no identified additional impact on library resources or services related to this course. Teaching and Learning Support: A laptop computer, screen, and a data projector are required for in-class lectures. All currently available: classroom for students, library, computing (IT) facilities, CLEW, and a classroom with one computer terminal (web accessible) per registered student. There is no identified additional impact on teaching and learning support related to this course. Student Support Services: There is no identified impact on student support services related to this course. Space and Facilities: The delivery of the course materials will be completed utilizing a mixture of formats, including standard lectures, cooperative and group learning, and guided discussions. As such, the only identified impact on space and facilities related to this course is the utilization of existing teaching space. Equipment (and Maintenance): There is no identified impact on student support services related to this course.

7 TITLE OF THE PROGRAM/CERTIFICATE: Master of Medical Biotechnology (MMB) DEPARTMENT/SCHOOL: Chemistry and Biochemistry FACULTY: Science Proposed change(s) effective as of: September 2012 NEW COURSE PROFILE Course # and Title: Proteomics and Biological Mass Spectrometry Calendar Description Calendar descriptions should be written in the third person and should provide a general outline of the course material. Where appropriate, examples of topics or themes, which might be covered in the course, should also be provided. This course will focus on the theory and applications of biological mass spectrometry with particular emphasis on its use in proteome platforms. The most common types of ionization methods and mass analyzers will be thoroughly presented including data interpretation. A major part of the course will cover the applications of this technique in identifying multi-protein complexes, mapping post-translational modifications, and quantitative proteomics. Finally, various techniques that are commonly interfaced with the mass spectrometer will be introduced in order to emphasize proper sample preparation and stimulate discussion on applying mass spectrometry to graduate student s own projects. Other Course Information Please complete the following tables. Credit weight Total contact hours In-class e- learning Delivery format Distanc e Other flexible learning delivery [please specify] 1 36 X 3 h/wk Breakdown of contact hours/week Lecture Tutorial Lab. Co-op/ practicum the MMB program. Prerequisites Corequisites Antirequisites Registration restricted to those enrolled in Crosslisted with: Required course X Optional course Replacing old course*** [provide old course number] ***Replacing Old Course (this does not mean that the former course will be deleted from the calendar. If it is to be deleted, a Form E must be completed.) Will students be able to obtain credit for the new course and the course(s) that it is replacing? This course does not replace any exiting course. Students will only be able to obtain credit for this course.

8 B. RATIONALE PROGRAM DEVELOPMENT COMMITTEE B.1 Course Goal(s) Please provide a statement about the purpose of the course within the program of study or as an option. Mass spectrometry is a powerful analytical tool that is prevalent in biotechnology and systems biology laboratories. Traditionally, most of the scientists that perform biological mass spectrometry are analytical chemists. Although analytical chemists have brought this methodology to the forefront in biological sciences there is a great need for biochemists and biologists to be trained in this technique in order to best apply this tool to more complex, dynamic biological problems. B.2 LEARNING OUTCOMES (QAF section 2.1.1, 2.1.3, and 2.1.6) Please complete the following table. State the specific learning outcomes that make up the goal of the course (what will students know and be able to do at the end of this course?) and link the learning outcomes to the Characteristics of a University of Windsor Graduate outlined in To Greater Heights by listing them in the appropriate rows. Please note that a learning outcome may link to more than one of the specified Characteristics of a University of Windsor Graduate, and that a single course may not touch on each of the Characteristics. Each University of Windsor program should produce graduates that are able to demonstrate each of the nine characteristics approved in To Greater Heights. Information on learning outcomes is appended to this form (Appendix A). The information is also on the PDC Website or through the University Secretariat. Proposers are also strongly encouraged to contact the Office of the Vice-Provost, Teaching and Learning for assistance with the articulation of learning outcomes. Learning Outcomes (see Appendix A for more on learning outcomes) At the end of this course, the successful student will know and be able to: know the structure-fragmentation principles when analyzing biomolecules using mass spectrometry. read the pertinent literature and write protocols for proteomic and mass spectrometry studies of existing biological problems. critically analyze recent mass spectrometry and proteomics literature. analyze mass spectrometry data including peptide sequencing, mapping protein modifications, and interpreting isotope labeling data. Characteristics of a University of Windsor Graduate A U of Windsor graduate will have the ability to demonstrate: A. the acquisition, application and integration of knowledge B. research skills, including the ability to define problems and access, retrieve and evaluate information (information literacy) C. critical thinking and problem-solving skills D. literacy and numeracy skills E. responsible behaviour to self, others and society prepare and orally present seminars summarizing high impact recent research in the area of proteomics and biological mass spectrometry. F. interpersonal and communications skills G. teamwork, and personal and group leadership skills

9 Learning Outcomes (see Appendix A for more on learning outcomes) At the end of this course, the successful student will know and be able to: Characteristics of a University of Windsor Graduate A U of Windsor graduate will have the ability to demonstrate: articulate how to advance a research project using proteomic and mass spectrometry based methods. H. creativity and aesthetic appreciation I. the ability and desire for continuous learning B.3 Demand for Course Please provide as much information on projected enrolment as possible. Projected enrolment levels for the first 5 years of the new course. Year 1 Year 2 Year 3 Year 4 Year What will be the impact of offering the new course on enrolments in existing courses in the program or Department? As this course is specifically designed for utilization within the Master of Medical Biotechnology (MMB) program, which is a course-based, cohort-managed professional graduate degree, we do not foresee any impact on existing courses in the program or Department by offering this new course. B.4 Student Workload Average number of hours per week that the student will be expected to devote to: 3 Lectures 0 Tutorials 0 Labs 0 Practical experience 2 Independent Study 1.5 Reading for the course 1 Work for assessment (essays, papers, projects, laboratory work) 1 Meeting with others for group work/project assignments 1.5 Studying for tests/examinations Other: [specify] How does the student workload for this course compare with other similar courses in the department/program area? Similar to others C. RESOURCES C.1 Available Faculty and Staff Resources (QAF sections 2.1.7, 2.1.8, and ) Describe all faculty and staff resources (e.g., administrative, teaching, supervision) from all affected areas/departments currently available and actively committed to support the new course. All of the faculty identified are currently or have been actively involved in graduate student supervision and notably, have extensive experience in supervising and instructing international graduate students from a diverse range of cultural and educational backgrounds. Furthermore, all of the above are actively involved in the academic activities of the department including seminars, conferences, etc. As it is a course-based Masters, no research supervision will be required. The instructors will be responsible to the MMB students within their specific graduate course for office hours, feedback, etc. They will be assisted in

10 their duties by the 'Biotech. Coordinator' who will assist instructors with some general duties such as course assessment design and implementation for the MMB students, and tabulation and coordination of their grades. C.1.1 Provide an assessment of faculty expertise available and committed to actively support the new course. Prof. Otis Vacratsis has an established successful research and publication record in the application of mass spectrometry to the study of biological/biochemical phenomena. C.1.2 Describe the area s expected reliance on, and the role of adjunct, limited-term, and sessional faculty in delivering the new course. It is expected that our tenured faculty, within the Department of Chemistry and Biochemistry, would deliver this course. If not, faculty from collaborating academic units and/or collaborating institutions would be drawn upon to meet the high level expertise required within this discipline. As this course relies heavily on the utilization of novel diagnostics techniques the utilization of academic and industry leaders in the field of medical biotechnology may be asked to present special guest lectures/seminars. C.2 Resource Implications for Other Campus Units (MTCU sections 3 and 4) Describe the reliance of the proposed new course on existing resources from other campus units, including for example: faculty teaching, equipment or facilities outside the proposer s control, external resources requiring maintenance or upgrading using external resources Provide relevant details. The Centre for Executive and Professional Education would assist in the recruitment of qualified applicants from government, academia, or industry. C.3 Anticipated New Resources (QAF sections 2.1.7, and 2.1.9; MTCU section 4) List all anticipated new resources originating from within the area, department or faculty (external grants, donations, government grants, etc.) and committed to supporting the revisions to this program. None C.4 Planned Reallocation of Resources and Cost-Savings (QAF section and 2.1.9; MTCU section 4) Identify all opportunities for internal reallocation of resources and cost savings identified and pursued by the area/department in support of the new course. (e.g., streamlining existing programs and courses, deleting courses, etc.)? This proposed course is part of the Faculty of Science / Department of Chemistry and Biochemistry s Master of Medical Biotechnology program. There is no planned reallocation of resources or cost-savings identified; however, this course is part of a cost recovery program and thereby will not place any additional pressure on existing programs or courses. C.5 Additional Resources Required Resources Requested (QAF section and 2.1.9) Describe all additional faculty, staff and GA/TA resources (in all affected areas and departments) required to offer the new course.

11 Faculty: There are no additional faculty resources that will be needed related to the teaching of this course. Staff: There are no additional staff resources that will be needed related to the teaching of this course. GA/TAs: There are no additional GA/TA resources that will be needed related to the teaching of this course. C.5.1 Describe all additional institutional resources and services required by all affected areas or departments to offer the new course, including library, teaching and learning support services, student support services, space and facilities, and equipment and its maintenance. Library Resources and Services: There is no identified impact on library resources or services related to this course. Teaching and Learning Support: There is no identified impact on teaching and learning support related to this course. Student Support Services: There is no identified impact on student support services related to this course. Space and Facilities: The delivery of the course materials will be completed utilizing a mixture of formats, including standard lectures, cooperative and group learning, and guided discussions. As such, the only identified impact on space and facilities related to this course is the utilization of existing teaching space. Equipment (and Maintenance): No new equipment will be required. As this is a full cost-recovery program, no additional institutional resources will be required; any maintenance costs associated with this program will be covered by this program.

12 TITLE OF THE PROGRAM/CERTIFICATE: Master of Medical Biotechnology (MMB) DEPARTMENT/SCHOOL: Chemistry and Biochemistry FACULTY: Science Proposed change(s) effective as of: September 2012 NEW COURSE PROFILE Course # and Title: Drugs: From Discovery to Market Calendar Description Calendar descriptions should be written in the third person and should provide a general outline of the course material. Where appropriate, examples of topics or themes, which might be covered in the course, should also be provided. This course will introduce students to the relevant concepts and applications of organic synthesis and chemical characterization that lead to the discovery and rational design of therapeutic agents. In addition, the course will cover the fundamentals of the clinical trials process and best regulatory practise's in pharmaceutical industries. Other Course Information Please complete the following tables. Credit weight Total contact hours In-class e- learning Delivery format Distanc e Other flexible learning delivery [please specify] 1 3/wk X X (seminars from invited speakers that are experts in relevant fields). Breakdown of contact hours/week Lecture Tutorial Lab. Co-op/ practicum 3 h/wk the MMB program. Prerequisites Corequisites Antirequisites Registration restricted to those enrolled in Crosslisted with: Required course X Optional course Replacing old course*** [provide old course number] ***Replacing Old Course (this does not mean that the former course will be deleted from the calendar. If it is to be deleted, a Form E must be completed.) Will students be able to obtain credit for the new course and the course(s) that it is replacing? This course does not replace any exiting course. Students will only be able to obtain credit for this course. B. RATIONALE B.1 Course Goal(s) Please provide a statement about the purpose of the course within the program of study or as an option. The vast majority (~90+%) of all therapeutic drugs are synthetic, being synthesized within labs. The objective of this course is to understand organic chemistry, biochemical, physicochemical and biological concepts of molecular interactions that are of importance and relevance to drug design. This will build upon our understanding of the structures and functions of biomolecules (e.g., proteins, enzymes, receptors, nucleic acids) as well as their interactions with known therapeutic agents. In particular, we will discuss how biomolecules

13 become drug targets. Furthermore, we will explore how rational drug discoveries and designs employ the knowledge of potential inter-molecular biomolecule ligand interactions (pharmacodynamics), and the knowledge of their bodily functions affecting the absorption, distribution, metabolism and elimination of therapeutic agents (pharmacokinetics). Another important goal of this course is to expose the students to the regulatory aspects of drug development and manufacturing, including Patent Law and Work Health and Safety. In addition, the student will be introduced to the large role globalization plays in the discovery, design, manufacture, distribution and marketing of therapeutic drugs. To this end, the course will give a thorough understanding of the global regulatory processes governing clinical trials drug manufacturing and commercialization. By the end of this course, students will have a(n): (i) understanding of the importance of organic synthesis and pharmacology in drug discovery and development, (ii) broad understanding of fundamental organic chemistry and biochemistry in applied sciences (pharmacy and medicine), (iii) understanding of the clinical trial process and best regulatory practises in pharmaceutical and related industries. B.2 LEARNING OUTCOMES (QAF section 2.1.1, 2.1.3, and 2.1.6) Please complete the following table. State the specific learning outcomes that make up the goal of the course (what will students know and be able to do at the end of this course?) and link the learning outcomes to the Characteristics of a University of Windsor Graduate outlined in To Greater Heights by listing them in the appropriate rows. Please note that a learning outcome may link to more than one of the specified Characteristics of a University of Windsor Graduate, and that a single course may not touch on each of the Characteristics. Each University of Windsor program should produce graduates that are able to demonstrate each of the nine characteristics approved in To Greater Heights. Information on learning outcomes is appended to this form (Appendix A). The information is also on the PDC Website or through the University Secretariat. Proposers are also strongly encouraged to contact the Office of the Vice-Provost, Teaching and Learning for assistance with the articulation of learning outcomes. Learning Outcomes (see Appendix A for more on learning outcomes) At the end of this course, the successful student will know and be able to: Describe and discuss the interaction of ligands (drugs) and drug targets (biomolecules). retrieve information, such as primary and crystal structures, of possible drug targets (i.e. enzymes, receptors) from publicly available databases and analyze them for their potential interaction sites to ligands/drugs. Design potentially novel chemicals with therapeutic properties based on the structure of a lead compound and its interaction to target. prepare and compose a standard operation procedure (SOP) for a simulated organic synthesis and characterization. Characteristics of a University of Windsor Graduate A U of Windsor graduate will have the ability to demonstrate: A. the acquisition, application and integration of knowledge B. research skills, including the ability to define problems and access, retrieve and evaluate information (information literacy) C. critical thinking and problem-solving skills D. literacy and numeracy skills E. responsible behaviour to self, others and society

14 Learning Outcomes (see Appendix A for more on learning outcomes) At the end of this course, the successful student will know and be able to: Characteristics of a University of Windsor Graduate A U of Windsor graduate will have the ability to demonstrate: Debate, within the class environment, the importance and pitfalls of different technologies used in pharmaceutical industries F. interpersonal and communications skills G. teamwork, and personal and group leadership skills H. creativity and aesthetic appreciation Participate in discussion following presentations offered by experts/invitees from biotechnology and pharmaceutical industries I. the ability and desire for continuous learning B.3 Demand for Course Please provide as much information on projected enrolment as possible. Projected enrolment levels for the first 5 years of the new course. Year 1 Year 2 Year 3 Year 4 Year What will be the impact of offering the new course on enrolments in existing courses in the program or Department? As this course is specifically designed for utilization within the Master of Medical Biotechnology (MMB) program, which is a course-based, cohort-managed professional graduate degree, we do not foresee any impact on existing courses in the program or Department by offering this new course. Student Workload Provide information on the expected workload per week of a student enrolled in this course. NOTE: Student workload should be consistent with the credit weight assigned to the course. Average number of hours per week that the student will be expected to devote to: 3 Lectures 0 Tutorials 0 Labs 2 Practical experience 1 Independent Study 1 Reading for the course 1 Work for assessment (essays, papers, projects, laboratory work) 1 Meeting with others for group work/project assignments 1 Studying for tests/examinations Other: [specify] How does the student workload for this course compare with other similar courses in the department/program area? Similar to others

15 C. RESOURCES C.1 Available Faculty and Staff Resources (QAF sections 2.1.7, 2.1.8, and ) Describe all faculty and staff resources (e.g., administrative, teaching, supervision) from all affected areas/departments currently available and actively committed to support the new course. All of the faculty identified (in particular Prof. Sirinart Ananvoranich and Bulent Mutus) are currently or have been actively involved in graduate student supervision and notably, have extensive experience in supervising and instructing international graduate students from a diverse range of cultural and educational backgrounds. Furthermore, all of the above are actively involved in the academic activities of the department including seminars, conferences, etc. As it is a course-based Masters, no research supervision will be required. The instructors will be responsible to the MMB students within their specific graduate course for office hours, feedback, etc. They will be assisted in their duties by the 'Biotech. Coordinator' who will assist instructors with some general duties such as course assessment design and implementation for the MMB students, and tabulation and coordination of their grades. C.1.1 Provide an assessment of faculty expertise available and committed to actively support the new course. Prof. Sirinart Ananvoranich research interests lie in the field of nucleic acid vectors of parasite infection and regulation. As such, she is an expert in the biochemistry of nucleic acids and their experimental investigation. Prof. Bulent Mutus currently holds a Research Leadership Chair in Biochemistry in recognition of his outstanding research record, publications and achievements. As one of the most senior members of the Biochemistry Division within our department of Chemistry and Biochemistry he is intimately familiar with our programs and has been involved in its design and adaptation to the new challenges facing today's undergraduate and graduate students. C.1.2 Describe the area s expected reliance on, and the role of adjunct, limited-term, and sessional faculty in delivering the new course. It is expected that our tenured faculty, within the Department of Chemistry and Biochemistry, would deliver this course. If not, faculty from collaborating academic units and/or collaborating institutions would be drawn upon to meet the high level expertise required within this discipline. The Centre for Executive and Professional Education would assist in the recruitment of qualified applicants from government, academia, or industry. C.2 Resource Implications for Other Campus Units (MTCU sections 3 and 4) Describe the reliance of the proposed new course on existing resources from other campus units, including for example: faculty teaching, equipment or facilities outside the proposer s control, external resources requiring maintenance or upgrading using external resources Provide relevant details. None C.3 Anticipated New Resources (QAF sections 2.1.7, and 2.1.9; MTCU section 4) List all anticipated new resources originating from within the area, department or faculty (external grants, donations, government grants, etc.) and committed to supporting the revisions to this program. None

16 C.4 Planned Reallocation of Resources and Cost-Savings (QAF section and 2.1.9; MTCU section 4) Identify all opportunities for internal reallocation of resources and cost savings identified and pursued by the area/department in support of the new course. (e.g., streamlining existing programs and courses, deleting courses, etc.)? This proposed course is part of the Faculty of Science / Department of Chemistry and Biochemistry s Master of Medical Biotechnology program. There is no planned reallocation of resources or cost-savings identified; however, this course is part of a cost recovery program and thereby will not place any additional pressure on existing programs or courses. C.5 Additional Resources Required Resources Requested (QAF section and 2.1.9) Describe all additional faculty, staff and GA/TA resources (in all affected areas and departments) required to offer the new course. Faculty: There are no additional faculty resources that will be needed related to the teaching of this course. Staff: There are no additional staff resources that will be needed related to the teaching of this course. GA/TAs: There are no additional GA/TA resources that will be needed related to the teaching of this course. C.5.1 Describe all additional institutional resources and services required by all affected areas or departments to offer the new course, including library, teaching and learning support services, student support services, space and facilities, and equipment and its maintenance. Library Resources and Services: There is no identified impact on library resources or services related to this course. Teaching and Learning Support: There is no identified impact on teaching and learning support related to this course. Student Support Services: There is no identified impact on student support services related to this course. Space and Facilities: The delivery of the course materials will be completed utilizing a mixture of formats, including standard lectures, cooperative and group learning, and guided discussions. As such, the only identified impact on space and facilities related to this course is the utilization of existing teaching space. Equipment (and Maintenance): There is no identified impact on equipment by this course.

17 TITLE OF THE PROGRAM/CERTIFICATE: Master of Medical Biotechnology (MMB) DEPARTMENT/SCHOOL: Chemistry and Biochemistry FACULTY: Science Proposed change(s) effective as of: September 2012 NEW COURSE PROFILE Course # and Title: Clinical Biochemistry Calendar Description: Clinical Biochemistry is concerned with the analysis and testing of bodily fluids and tissues. This field is fundamental to patient care and contributes significantly to the diagnosis, treatment, monitoring and prognosis of disease processes. This course is designed to introduce students to the field by covering areas including quality control in clinical testing, automation, clinical enzymology and biomarker discovery. In addition, the course will focus on the design, testing and commercialization of specific clinical tests for: liver function, abnormalities in lipid metabolism, diabetes and related metabolic disorders, fertility/reproduction, cancer and therapeutic drug monitoring. Upon completion of the course the students will get a broad exposure of the current state of the technology for the analysis of clinical samples as well as learning the basic principles in design and testing of clinical assays for a wide range of analytes. Calendar descriptions should be written in the third person and should provide a general outline of the course material. Where appropriate, examples of topics or themes, which might be covered in the course, should also be provided. Other Course Information Please complete the following tables. Credit weight Total contact hours In-class e- learning Delivery format Distanc e Other flexible learning delivery [please specify] 1 3/week X 2h/wk 1h/wk Breakdown of contact hours/week Lecture Tutorial Lab. Co-op/ practicum the MMB program. Prerequisites Corequisites Antirequisites Registration restricted to those enrolled in Crosslisted with: Required course X Optional course Replacing old course*** [provide old course number] ***Replacing Old Course (this does not mean that the former course will be deleted from the calendar. If it is to be deleted, a Form E must be completed.) Will students be able to obtain credit for the new course and the course(s) that it is replacing? This course does not replace any exiting course. Students will only be able to obtain credit for this course. B. RATIONALE

18 B.1 Course Goal(s) Please provide a statement about the purpose of the course within the program of study or as an option. Clinical Biochemistry is a major driver of the biotechnology industry. It is estimated that the total healthcare spending in 2010, in the USA was ~$3 trillion. Clinical biochemistry/laboratory medicine portion is estimated to be ~15% (or $ 450 billion per annum). The future advances in clinical chemistry have the potential to lower health care costs by providing testing methodologies to prevent, diagnose, treat and monitor disease. This course will expose the students to current methods and procedures for analysis and reporting of clinical samples as well as how analytical tests are adapted and marketed for use in the clinical setting. As such, the proposed clinical biochemistry course is a requisite component of a medical biotechnology program. B.2 LEARNING OUTCOMES (QAF section 2.1.1, 2.1.3, and 2.1.6) Please complete the following table. State the specific learning outcomes that make up the goal of the course (what will students know and be able to do at the end of this course?) and link the learning outcomes to the Characteristics of a University of Windsor Graduate outlined in To Greater Heights by listing them in the appropriate rows. Please note that a learning outcome may link to more than one of the specified Characteristics of a University of Windsor Graduate, and that a single course may not touch on each of the Characteristics.Each University of Windsor program should produce graduates that are able to demonstrate each of the nine characteristics approved in To Greater Heights. Information on learning outcomes is appended to this form (Appendix A). The information is also on the PDC Website or through the University Secretariat. Proposers are also strongly encouraged to contact the Office of the Vice-Provost, Teaching and Learning for assistance with the articulation of learning outcomes. Learning Outcomes (see Appendix A for more on learning outcomes) At the end of this course, the successful student will know and be able to: Describe and discuss the interaction of ligands (drugs) and drug targets (biomolecules). retrieve information, such as primary and crystal structures, of possible drug targets (i.e. enzymes, receptors) from publicly available databases and analyze them for their potential interaction sites to ligands/drugs. Design potentially novel chemicals with therapeutic properties based on the structure of a lead compound and its interaction to target. prepare and compose a standard operation procedure (SOP) for a simulated organic synthesis and characterization. Characteristics of a University of Windsor Graduate A U of Windsor graduate will have the ability to demonstrate: A. the acquisition, application and integration of knowledge B. research skills, including the ability to define problems and access, retrieve and evaluate information (information literacy) C. critical thinking and problem-solving skills D. literacy and numeracy skills E. responsible behaviour to self, others and society Debate, within the class environment, the importance and pitfalls of different technologies used in pharmaceutical industries F. interpersonal and communications skills

19 Learning Outcomes (see Appendix A for more on learning outcomes) At the end of this course, the successful student will know and be able to: Characteristics of a University of Windsor Graduate A U of Windsor graduate will have the ability to demonstrate: G. teamwork, and personal and group leadership skills H. creativity and aesthetic appreciation Participate in discussion following presentations offered by experts/invitees from biotechnology and pharmaceutical industries I. the ability and desire for continuous learning B.3 Demand for Course Please provide as much information on projected enrolment as possible. Projected enrolment levels for the first 5 years of the new course. Year 1 Year 2 Year 3 Year 4 Year What will be the impact of offering the new course on enrolments in existing courses in the program or Department? As this course is specifically designed for utilization within the Master of Medical Biotechnology (MMB) program, which is a course-based, cohort-managed professional graduate degree, we do not foresee any impact on existing courses in the program or Department by offering this new course. B.4 Student Workload Provide information on the expected workload per week of a student enrolled in this course. NOTE: Student workload should be consistent with the credit weight assigned to the course. Average number of hours per week that the student will be expected to devote to: 2 Lectures 1 Tutorials 0 Labs 2 Practical experience 1 Independent Study 1 Reading for the course 1 Work for assessment (essays, papers, projects, laboratory work) 1 Meeting with others for group work/project assignments 1 Studying for tests/examinations Other: [specify] How does the student workload for this course compare with other similar courses in the department/program area?

20 This work load is similar to other graduate courses. C. RESOURCES C.1 Available Faculty and Staff Resources (QAF sections 2.1.7, 2.1.8, and ) Describe all faculty and staff resources (e.g., administrative, teaching, supervision) from all affected areas/departments currently available and actively committed to support the new course. All of the faculty identified are currently or have been actively involved in graduate student supervision and notably, have extensive experience in supervising and instructing international graduate students from a diverse range of cultural and educational backgrounds. Furthermore, all of the above are actively involved in the academic activities of the department including seminars, conferences, etc. As it is a course-based Masters, no research supervision will be required. The instructors will be responsible to the MMB students within their specific graduate course for office hours, feedback, etc. They will be assisted in their duties by the 'Biotech. Coordinator' who will assist instructors with some general duties such as course assessment design and implementation for the MMB students, and tabulation and coordination of their grades. C.1.1 Provide an assessment of faculty expertise available and committed to actively support the new course. It is expected that our tenured faculty, within the Department of Chemistry and Biochemistry, would deliver this course. If not, faculty from collaborating academic units and/or collaborating institutions would be drawn upon to meet the high level expertise required within this discipline. Prof. Bulent Mutus currently holds a Research Leadership Chair in Biochemistry in recognition of his outstanding research record, publications and achievements. As one of the most senior members of the Biochemistry Division within our department of Chemistry and Biochemistry he is intimately familiar with our programs and has been involved in its design and adaptation to the new challenges facing today's undergraduate and graduate students. C.1.2 Describe the area s expected reliance on, and the role of adjunct, limited-term, and sessional faculty in delivering the new course. It is expected that our tenured faculty, within the Department of Chemistry and Biochemistry, would deliver this course. If not, faculty from collaborating academic units and/or collaborating institutions would be drawn upon to meet the high level expertise required within this discipline. The Centre for Executive and Professional Education would assist in the recruitment of qualified applicants from government, academia, or industry. C.2 Resource Implications for Other Campus Units (MTCU sections 3 and 4) Describe the reliance of the proposed new course on existing resources from other campus units, including for example: faculty teaching, equipment or facilities outside the proposer s control, external resources requiring maintenance or upgrading using external resources Provide relevant details. None C.3 Anticipated New Resources (QAF sections 2.1.7, and 2.1.9; MTCU section 4) List all anticipated new resources originating from within the area, department or faculty (external grants,

21 donations, government grants, etc.) and committed to supporting the revisions to this program. None C.4 Planned Reallocation of Resources and Cost-Savings (QAF section and 2.1.9; MTCU section 4) Identify all opportunities for internal reallocation of resources and cost savings identified and pursued by the area/department in support of the new course. (e.g., streamlining existing programs and courses, deleting courses, etc.)? This proposed course is part of the Faculty of Science / Department of Chemistry and Biochemistry s Master of Medical Biotechnology program. There is no planned reallocation of resources or cost-savings identified; however, this course is part of a cost recovery program and thereby will not place any additional pressure on existing programs or courses. C.5 Additional Resources Required Resources Requested (QAF section and 2.1.9) Describe all additional faculty, staff and GA/TA resources (in all affected areas and departments) required to offer the new course. Faculty: There are no additional faculty resources that will be needed related to the teaching of this course. Staff: There are no additional staff resources that will be needed related to the teaching of this course. GA/TAs: There are no additional GA/TA resources that will be needed related to the teaching of this course. C.5.1 Describe all additional institutional resources and services required by all affected areas or departments to offer the new course, including library, teaching and learning support services, student support services, space and facilities, and equipment and its maintenance. Library Resources and Services: There is no identified impact on library resources or services related to this course. Teaching and Learning Support: There is no identified impact on teaching and learning support related to this course. Student Support Services: There is no identified impact on student support services related to this course. Space and Facilities: