Leading causes of death in Israel

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1 Health Information Division Leading causes of death in Israel Nehama Goldberger, Myriam Aburbeh, Ziona Haklai September 2015

2 Contents Leading causes of death in Israel summary... 1 Trends... 1 International Comparison... 3 Ranking of leading causes of death in Israel by age... 6 Multiple causes of death... 9 Tables - Leading causes of death by year Appendix detailed cause of death,

3 Leading causes of death in Israel - summary The publication Leading causes of death, presents trends in mortality rates by cause of death, age, gender and year in the last decade, international comparisons with Europe, Canada and the USA, and follows the methodology of the USA publications on leading causes of death 1. The publication was prepared by the Health Information Division of the Ministry of Health and is a continuation of a series of publications on this subject. The information is based on the notification of death form legally required by the Ministry of the Interior. The coding of death causes is done by the Central Bureau of Statistics (CBS), based on this form and supplementary information from other data sources. This notification of death form includes the immediate cause of death, the train of events that led to this cause, and other significant diseases, conditions or injuries that contributed to death but not directly resulting in previous chain of events. Data is presented here on the underlying cause of death, defined as the cause that initiated the train of events leading to death, or the circumstances of the accident or violence that produced the fatal injury, and chosen by the CBS from the causes written by the doctor on the notification of death form according to definitions and conventions of the International Classification of Diseases. In addition, data is presented on multiple causes of death, which include all causes mentioned on the death notification. Trends In the last decade, rates of death from most causes have been decreasing. Crude total mortality decreased by about a tenth between 2000 and 2012, by 14% for males and 9% for females. Cancer is the leading cause of death from 1999 in both genders, followed by heart disease. For most of the period, , cerebrovascular disease was the third and diabetes the fourth cause. These four causes together accounted for about half of all deaths in 2012 (53% for males, 52% for females), compared to a higher proportion in 2000 (57% for males, 60% for females). The average crude mortality rate for showed a significant decrease compared to of about a third for heart disease (35% for males, 32% for females), and about a quarter for cerebrovascular disease (27% for males, 23% for females) and diabetes (22% for males, 25% for females). Deaths from accidents decreased by about a third for males (35%) and 17% for females. The mortality rate decreased for chronic lower respiratory disease (CLRD) by about a fifth over this period (19% for males, 23% for females). However, an increase in crude mortality rate for compared to was found for other causes. The highest increase was for dementia, which more than doubled, an increase of 111% for males and 116% for females. Other high increases were for mortality due to septicemia (71% for both genders), Alzheimer s disease (57% for males, 78% for females), influenza and pneumonia (13% in males, 25% in females), pneumonitis due to solids and liquids (30% in males, 49% in females). Mortality rates from kidney disease rose till 2006, but were somewhat lower and stable in the following years 1 Leading causes of death in Israel,

4 Trends Mortality Rates by cause, year moving average/100,000 population Males Females Malignant Cerebrovascular disease Diabetes Kidney disease Malignant Cerebrovascular disease Diabetes Dementia Kidney disease 3- year moving average mortality rate: Percentage change between and Males Females Malignant -4% Malignant % Cerebrovascular disease Diabetes Kidney disease -27% -22% 6% Cerebrovascular disease Diabetes Dementia % Kidney disease Ministry of health, Israel

5 International Comparison The age adjusted mortality rate in Israel was low in comparison to the USA and most European countries. In 2012, the rate in Israel was 928 per 100,000 population, compared to a similar rate in Italy (923) and lower rates in France (871), Canada (881), Switzerland (882) and Spain (898). In 17 other selected European countries and in the USA, rates were higher. Amongst males, Israel had the lowest mortality rate of all European countries (1,068), with a lower rate only in Canada (1,051), while amongst females, Israel s rates were 5 th lowest in Europe (814), after France (669), Spain (703), Switzerland (739), Italy (755) and also Canada (748). Age adjusted* mortality rates per 100,000 population by country, 2012 Total Males Females France** Canada** 1,051.5 France** Canada** Israel 1,068.4 Spain Switzerland Switzerland 1,086.3 Switzerland Spain United Kingdom 1,156.6 Canada** Italy France** 1,158.0 Italy Israel Spain 1,162.1 EU-15 countries EU-15 countries Italy 1,167.4 Israel Sweden Sweden 1,173.3 Finland 824 United Kingdom EU-15 countries 1,190.9 Sweden Norway Germany 1,196.8 Portugal 839 Germany Norway 1,211.3 Germany Austria USA 1,235.9 Austria Netherlands Netherlands 1,237.2 Norway Finland Greece 1,243.7 Belgium Ireland Austria 1,257.3 Ireland Greece Ireland 1,259.6 Netherlands USA Denmark 1,316.3 Greece Belgium Finland 1,319.5 United Kingdom Portugal Belgium 1,321.4 USA Denmark Portugal 1,349.9 Denmark Czech Republic Czech Republic 1,656.3 Poland 1,030.5 Poland Poland 1,767.0 Czech Republic 1,088.4 Slovak Republic Slovak Republic 1,862.3 Slovak Republic 1,186.1 Hungary Hungary 1,939.7 Hungary 1,215.1 Romania Romania 1,985.5 Romania 1,312.8 *Adjusted to the new European Standard Population defined by Eurostat, 2012 ** 2011 data Leading causes of death in Israel,

6 International comparison - Ranking of causes of death Cancer was the leading cause of death in Israel in 2012, and heart disease the second ranking cause, as in the USA, Canada and most West European countries, other than Finland, Germany, Sweden, Austria and Greece where the rank was reversed. The third cause of death in Israel was cerebrovascular disease, as in the average of the 15 Western EU countries, but the 4 th cause was diabetes, which had a similar rank only in Austria, was ranked 5 th in Italy and Portugal, 6 th in Germany and 7 th or higher in the USA, Canada and other European countries. Dementia, recently added to the Eurostat database was amongst the 5 leading causes in several countries, ranking 3 rd in Holland and Canada, 4 th in the USA, UK and Sweden, and 5 th in Norway, Denmark, Germany, Spain and for the 15 EU country average, but only 8 th in Israel. Accidents were the 3 rd ranked cause in the USA and France, and 4 th in the 15 EU countries, while only 8 th in Israel. CLRD were the 3rd cause in the USA, 4 th for the 15 EU countries and 4 th or 5 th for most European countries while only 7 th in Israel. However septicemia, which is an increasing cause in Israel, was ranked 5 th, while it was not amongst the 10 leading causes in most countries. Ranking of 10 leading causes of death comparison with the USA, Canada and Europe Rank Israel EU-15 countries USA Canada 1 Malignant Malignant Malignant 2 Malignant 3 Cerebrovascular disease Cerebrovascular disease CLRD Dementia 4 Diabetes CLRD Dementia Cerebrovascular disease 5 Dementia Cerebrovascular disease CLRD 6 Kidney disease Accidents Accidents Accidents 7 CLRD Pneumonia & Influenza Alzheimer's disease Diabetes 8 Dementia Diabetes Diabetes Alzheimer's disease 9 Pneumonia & Influenza Alzheimer's disease Pneumonia & Influenza Pneumonia & Influenza 10 Accidents Kidney disease Kidney disease Kidney disease Sources of data: Eurostat database Centers for Disease Control and Prevention, National Center for Health Statistics. Underlying Cause of Death on CDC WONDER Online Database, released Accessed at Statistics Canada. Table Deaths and mortality rate, by selected grouped causes, age group and sex, Canada, annual. EU-15 countries: A population weighted average including: Austria, Italy, Ireland, Belgium, United Kingdom, Germany, Denmark, Netherlands, Greece, Luxembourg, Spain, Portugal, Finland, France and Sweden. 4 Ministry of health, Israel

7 International comparison - Mortality rates by cause of death The age adjusted mortality rate was low in Israel compared to the USA, Canada and most European countries for cancer, heart disease, liver diseases, Alzheimer disease, accidents and suicide and lower than most European countries for cerebrovascular disease. But it was higher for septicemia, diabetes, kidney disease, and hypertension, 5.2, 2.4, 3.1 and 2.0 times higher respectively than the 15 EU country average. Mortality rates per 100,000 population by causes of death, 2012 Rate ratio EU-15 countries/israel rates 0.9 Malignant Cerebrovascular disease 0.8 CLRD 0.8 Dementia 0.7 Accidents 0.8 Pneumonia & Influenza 2.4 Diabetes 0.7 Alzheimer's disease 3.1 Kidney disease 0.5 Chronic liver disease 0.7 Suicides 2.0 Hypertension 0.7 Parkinson disease 5.2 Age adjusted* mortality USA Israel EU-15 countries *Adjusted to the new European Standard Population defined by Eurostat, 2012 Leading causes of death in Israel,

8 Ranking of leading causes of death in Israel by age On average in , cancer was the leading underlying cause of death for total deaths, and amongst females aged and males over 25. was the leading cause for females over 75, and the second cause for males over 45 and females aged For both genders, accidents were the leading cause for age and the second cause for Suicide was the second cause of death for males aged 15-24, and the 3 rd cause for males aged and females aged All ages: In recent years, about a quarter of all male and female deaths in Israel were from cancer, and a fifth from heart disease. The 3 rd and 4 th causes were cerebrovascular disease and diabetes, whose rates have been similar in recent years, and the following cause was kidney disease. These five leading causes account for about 60% of all deaths in recent years. Age 0-4: In 2012, conditions of the perinatal period (perinatal) and congenital malformations, deformations and chromosomal abnormalities (congenital conditions) were the leading causes, followed by accidents. These causes accounted for about 70% of deaths at this age. Age 5-14: Accidents and cancer were the leading causes for boys in 2012, while they had the opposite ranking for girls. For boys the 3 rd cause was congenital conditions, with the same number of deaths as accidents for girls. Age 15-24: In 2012, the external causes of accidents, suicide and homicide were the 3 leading causes for boys. For girls, too, accidents were the leading cause followed by cancer (4 th for boys) and suicide. Age 25-44: Cancer was the leading cause for both genders in 2012, suicide 2 nd and accidents 3 rd for males, with the reverse ranking for females, followed by heart disease 4 th and homicide 5 th for both genders. Amongst males, poisoning with undetermined intent was the next cause, which may be connected with drug abuse. Age 45-74: The 3 leading causes for both genders in 2012 were the same: cancer, heart disease, and diabetes while cerebrovascular disease was the 4 th cause for females aged and males aged Suicide was the 4 th cause for males aged and accidents the 5 th cause, while for females the 5 th cause was CLRD. For ages kidney disease was the 5 th cause for males and septicemia the 6 th with the reverse ranking for females. Age 75 and over: In 2012, cancer was the leading cause for males and heart disease the second, the ranking was reversed for females. Cerebrovascular disease was the 3 rd cause for both genders, kidney disease 4 th for males and diabetes 4 th for females and 5 th for males. ranked 5 th for females and 6 th for males. Dementia, a disease which has increased considerably as underlying cause in recent years, was 6 th for females. 6 Ministry of health, Israel

9 Ranking of 10 leading causes, by age, Males Absolute numbers and rate per 100,000 population Rank Total Kidney disease 2, , Accidents 2, CLRD 1, Pneumonia & influenza 1, Dementia 1, Pneumonia & influenza 17 ( 0.5) Homicide 15 ( 0.4) 10 ( 0.3) - Cerebrovascular disease - Other - Meningitis 6 ( 0.2) Accidents Suicides Homicide Malignant Poisoning undetermined intent - War/Terror 10 ( 0.5) Congenital conditions 9 ( 0.5) 7 ( 0.4) Pneumonia & influenza 6 ( 0.3) Malignant Accidents Suicide Homicide Poisoning undetermined intent Cerebrovascular disease CLRD Cerebrovascular disease Substance abuse Chronic liver disease Diabetes Malignant 3, , Diabetes Accidents Kidney disease CLRD Chronic liver disease Malignant 3, , Diabetes Malignant Perinatal causes , Congenital 10,089 conditions Cerebrovascular 142 disease 4.2 Accidents 3, Diabetes Malignant 3, Cerebrovascular disease Suicide Kidney disease Accidents Pneumonia & influenza Chronic liver disease Malignant 7,495 1, ,824 1,512.1 Cerebrovascular disease 2, Diabetes 1, Kidney disease 1, , CLRD 1, Dementia Pneumonia & influenza Accidents Leading causes of death in Israel,

10 Ranking of 10 leading causes, by age, Females Absolute numbers and rate per 100,000 population Rank Total Malignant 15, Heart disease 10, Cerebrovascular d. 3, Diabetes 3, , Kidney Disease 2, Perinatal Congenital conditions Accidents Malignant (0.4) Accidents Malignant Suicide ) 0.7( Congenital conditions 10 ( 0.6) Homicide 8 ( 0.5) Malignant Accidents Suicide Heart disease Homicide (0.6) Malignant 3, Diabetes Cerebrovascular d Accidents Malignant 3, Diabetes Cerebrovascular d Kidney disease ,711 1,322.9 Malignant 7,799 1,184.4 Cerebrovascular d. 3, Diabetes 2, Dementia 2, , Dementia 2, CLRD 1, Pneumonia & influenza 1, Accidents 1, Pneumonia & influenza - Homicide 11 ( 0.3) Meningitis 7 (0.2) Cerebrovascular d. 6 (0.2) Pneumonia & influenza 7 ( 0.4) - Congenital conditions - Poisoning undetermined intent 17 ( 0.5) Diabetes 16 (0.5) Chronic liver disease 15 ( 0.5) Kidney disease 13 (0.4) Kidney diseases CLRD Suicide Hypertension CLRD Pneumonia & influenza Accidents Hypertension Kidney disease 1, CLRD 1, Pneumonia & influenza 1, Hypertension 1, Ministry of health, Israel

11 Multiple causes of death Multiple causes of death include all causes mentioned on the death certificate. The ranking of multiple causes differs from that of the underlying cause. On average for the years , the leading cause mentioned most frequently on the notification of death form was heart disease, found in 43% of deaths. Cancer was 2 nd, in 28% of deaths, and septicemia was the 3 rd most frequent, mentioned in 27% of deaths. The 4 th cause was kidney disease for males (mentioned in 20% of their deaths) and hypertension for females (23% of deaths), which was the 5 th cause for males. Diabetes was 5 th in females and 6 th in males, and cerebrovascular disease was 7 th for both genders. Comparison of leading underlying and multiple causes , rate per 100,000 population Rank Underlying cause Total Males Females Multiple causes Underlying cause Multiple causes Underlying cause Multiple causes 1 Malignant Malignant Malignant Malignant Malignant Malignant Cerebrovascular d Cerebrovascular d Cerebrovascular d Diabetes 29.0 Hypertension Diabetes 27.0 Kidney disease Diabetes 31.0 Hypertension Kidney disease 20.2 Kidney disease 94.5 Kidney disease Hypertension 88.3 Kidney disease 20.1 Diabetes Diabetes Diabetes Kidney disease CLRD Accidents Dementia Pneumonia & influenza 11.8 Cerebrovascular d Pneumonia & influenza 63.8 Dementia 50.7 CLRD 36.8 Accidents 17.8 CLRD 17.2 Pneumonia & influenza 11.4 Suicide 9.3 Cerebrovascular d Pneumonia & influenza 65.4 CLRD 42.9 Dementia 36.9 Dementia 17.8 CLRD 13.9 Pneumonia & influenza 12.2 Accidents 11.6 Cerebrovascular d Dementia 64.2 Pneumonia & influenza 62.3 Anemias 36.0 Leading causes of death in Israel,

12 Tables: Leading causes of death by year Tables: leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population All ages - Males Cause of death Rate per 100,000 population Total Malignant Cerebrovascular disease Diabetes Kidney disease CLRD Accidents Flu/pneumonia Dementia Suicide Hypertension Pnemonitis due to solids and liquids Alzheimer s disease Liver disease Congenital conditions Perinatal conditions Other causes Absolute number Total 19,158 19,328 19,069 19,808 19,495 19,123 19,636 20,059 20,686 1 Malignant 4,451 4,762 4,754 4,915 4,963 4,974 5,201 5,201 5, ,234 3,675 3,549 3,889 3,515 3,381 3,447 3,397 3,245 3 Cerebrovascular disease 1,202 1,184 1,111 1, ,006 1,089 1,143 4 Diabetes 1,057 1,127 1,086 1,134 1,088 1,085 1,067 1,016 1,029 5 Kidney disease , CLRD Accidents Flu/pneumonia Dementia Suicide Hypertension Pnemonitis due to solids and liquids Alzheimer s disease Liver disease Congenital conditions Perinatal conditions Other causes 3,897 4,144 4,099 4,308 4,234 4,156 4,056 4,206 4, Ministry of Health, Israel

13 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population All ages - Females Cause of death Rate per 100,000 population Total Malignant Cerebrovascular disease Diabetes Dementia Kidney disease CLRD Flu/pneumonia Accidents Hypertension Alzheimer s disease Pnemonitis due to solids and liquids Congenital conditions Benign/other Anemias Parkinson s disease Other causes Absolute number Total 18,527 19,568 19,492 20,139 19,746 19,471 19,779 20,609 21,189 1 Malignant 4,427 4,775 4,871 4,924 5,020 4,949 5,179 5,087 5, ,964 3,793 3,658 3,806 3,563 3,410 3,316 3,459 3,280 3 Cerebrovascular disease 1,448 1,476 1,396 1,414 1,128 1,209 1,274 1,353 1,350 4 Diabetes 1,322 1,292 1,300 1,310 1,365 1,294 1,213 1,174 1, Dementia Kidney disease CLRD Flu/pneumonia Accidents Hypertension Alzheimer s disease Pnemonitis due to solids and liquids Congenital conditions Benign/other Anemias Parkinson s disease Other causes 3,603 3,996 3,942 4,147 3,990 3,942 3,961 4,196 4,518 Leading causes of death in Israel,

14 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Males Cause of death Rate per 100,000 population Total Malignant Diabetes Accidents Cerebrovascular disease Suicide Kidney disease CLRD Flu/pneumonia Liver disease Homicide Hypertension Congenital conditions Psychoactive substance abuse Benign/other Poisoning, undetermined intent Other causes Absolute number Total 8,892 8,527 8,351 8,540 8,309 8,108 8,280 8,355 8,483 1 Malignant 2,513 2,487 2,550 2,585 2,616 2,609 2,761 2,712 2, ,655 1,262 1,212 1,310 1,179 1,078 1,101 1,088 1,065 3 Diabetes Accidents Cerebrovascular disease Suicide Kidney disease CLRD Flu/pneumonia Liver disease Homicide Hypertension Congenital conditions Psychoactive substance abuse Benign/other Poisoning, undetermined intent Other causes 1,643 1,838 1,824 1,845 1,875 1,784 1,762 1,836 1, Ministry of Health, Israel

15 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Females Cause of death Rate per 100,000 population Total Malignant Diabetes Cerebrovascular disease Accidents Kidney disease CLRD Suicide Liver disease Flu/pneumonia Hypertension Benign/other Congenital conditions Dementia (0.5) (0.3) (0.2) (0.5) 0.7 (0.3) Viral hepatitis (0.5) Alzheimer s disease (0.6) (0.6) (0.5) (0.6) (0.5) (0.4) (0.3) (0.5) Other causes Absolute number Total 6,126 5,652 5,602 5,592 5,472 5,400 5,390 5,513 5,486 1 Malignant 2,447 2,450 2,419 2,479 2,523 2,499 2,604 2,512 2, Diabetes Cerebrovascular disease Accidents Kidney disease CLRD Suicide Liver disease Flu/pneumonia Hypertension Benign/other Congenital conditions Dementia Viral hepatitis Alzheimer s disease Other causes 978 1,044 1,035 1,099 1,013 1, ,092 1,108 Leading causes of death in Israel,

16 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Males Cause of death Rate per 100,000 population Total Perinatal conditions Congenital conditions Accidents (3.1) 5.5 (4.7) Flu/pneumonia.. (1.4) (1.3).... (2.2) 5 Malignant (3.9) (2.2) (3.5) (2.7) (3.9) (1.8) (3.5) (2.9) (1.7) (1.6) (2.4).. (1.8) (2.1) (2.0) (1.2) (1.2) 7 Meningitis Other causes Absolute number Total Perinatal conditions Congenital conditions Accidents Flu/pneumonia Malignant Meningitis Other causes Ministry of Health, Israel

17 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Females Cause of death Rate per 100,000 population Total Congenital conditions Perinatal conditions Accidents (5.1) (4.1) 6.6 (4.8) (4.4) (2.5) (5.0) (3.9) (4.3) 4 Malignant (2.2) (2.0).. (2.2) (1.7) (2.5) (1.3) (2.3) (1.5) 5 (4.8).. (3.4) (2.0) (1.4).. (1.9) (1.5).. 6 Homicide (1.9) (1.4) (1.5).. 8 Other causes Absolute number Total Congenital conditions Perinatal conditions Accidents Malignant Homicide Other causes Leading causes of death in Israel,

18 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Males Cause of death Rate per 100,000 population Total Accidents (2.2) Malignant (3.0) (2.6) (2.8) (2.3) 3.5 (1.8) 3 Congenital conditions (0.8) (1.1) (0.7) (0.9) (0.7) (1.1) (1.3) (1.1) (0.8).. (0.7).. (0.7) Suicide Homicide.... (0.7) Other causes Absolute number Total Accidents Malignant Congenital conditions Suicide Homicide Other causes Ministry of Health, Israel

19 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Females Cause of death Rate per 100,000 population Total Malignant (2.0) (2.6) (2.7) 3.1 (2.9) (2.0) (2.0) (2.7) (1.9) 2 Congenital conditions (0.9) (1.1).... (1.3) 3 Accidents (3.0) (1.6) (1.9) (1.6) (0.8) (1.8) (1.7).. (1.3) Flu/pneumonia Other causes Absolute number Total Malignant Congenital conditions Accidents Flu/pneumonia Other causes Leading causes of death in Israel,

20 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Males Cause of death Rate per 100,000 population Total Accidents Suicide Homicide Malignant (3.1) (1.6) (1.9) (1.2) (2.0) (1.9) (2.2) (1.5) (0.8) (1.5) 6 War/terror 4.5 (2.6) (2.6) (1.0) (2.7) (1.3).... (0.8) 7 Congenital conditions.... (1.0) (1.0) Other causes Absolute number Total Accidents Suicide Homicide Malignant War/terror Congenital conditions Other causes Ministry of Health, Israel

21 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Females Cause of death Total Rate per 100,000 population 1 Accidents Malignant (3.2) (2.5) (2.6) 3.6 (2.2) Suicide (2.7) 4.1 (3.3) 3.5 (2.8) (3.1) (2.5) 4 (1.9) (2.3) (3.2) 1.8 (1.2) (2.3) (1.7) (2.1) (2.2) 5 Congenital conditions (1.9) (1.1) (1.3).. (1.2) (1.0).... (1.2) 6 Flu/pneumonia (0.9) (0.9).... (0.8) 7 Kidney disease.. (1.0) Homicide Other causes Absolute number Total Accidents Malignant Suicide Congenital conditions Flu/pneumonia Kidney disease Homicide Other causes Leading causes of death in Israel,

22 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Males Cause of death Rate per 100,000 population Total Malignant Suicide Accidents Homicide Poisoning, undetermined intent (1.7) (1.8) 7 Cerebrovascular disease (1.8) 2.2 (1.3) (1.1) (1.5) (1.0) (1.1) (1.0) (1.2) 8 Aids (1.0) (0.8) (0.6) (1.8).. (1.1).. (0.8) (0.8) 9 Liver disease (1.7) (1.2) (1.2) (0.9) (1.0) (1.5) (1.2) (0.7) (0.8) 10 Congenital conditions (1.1) (0.8).. (0.7) (1.1) (0.8) (0.7).. (0.8) 11 Psychoactive substance abuse (2.3) (2.0) (1.9) (1.3) (1.4) (1.3) (1.1) (1.2) (0.7) 12 Viral hepatitis (1.3) (1.1) (0.7) (0.6) (0.6) 13.. (1.1) (1.0) (0.6) (0.6) (0.7) (0.5) (0.8) (0.5) 14 Diabetes (1.0) (1.2) (1.2) (1.3) (0.9) (1.3) (1.4) (0.7) (0.5) 15 Flu/pneumonia (1.7) (1.0) (0.6) (1.1) (0.7) (1.6) (0.7) (1.1).. 16 CLRD (1.2).. (1.0).. (0.5).. (0.7) (0.5).. 17 Kidney disease (1.0) (1.0) (0.8) (0.7) (1.0) (1.1) (0.7) (0.7).. 18 Other causes Absolute number Total 1, Malignant Suicide Accidents Homicide Poisoning, undetermined intent Cerebrovascular disease Aids Liver disease Congenital conditions Psychoactive substance abuse Viral hepatitis Diabetes Flu/pneumonia CLRD Kidney disease Other causes Ministry of Health, Israel

23 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Females Cause of death Rate per 100,000 population Total Malignant Accidents Suicide (1.9) (2.0) 3.8 (1.8) (1.9) (1.8) (1.7) (1.6) (1.7) 5 Homicide (2.1) (1.9) (1.6) (0.8) (1.0) (0.9) (1.4) (1.4) (0.7) (0.6).. (0.6) (0.7).. (0.9) (0.7) 7 Cerebrovascular disease (1.7) (1.1) (0.8) (0.6) (0.5) (1.4).... (0.6) 8 Aids (0.6) (0.5) 9 Liver disease.... (0.6) (0.5) (0.7) (0.5) 10 Congenital conditions.. (0.6) (0.9).. 11 CLRD (0.6) (0.9) (0.6) (0.5).. 12 Poisoning, undetermined intent.... (1.2) (1.3) (0.5).. (0.7) (0.7).. 13 Benign/other Diabetes (0.6).... (1.1) (0.5) (0.5) (0.8) (0.6).. 15 Flu/pneumonia.. (0.8).... (1.0) Viral hepatitis Psychoactive substance abuse Other causes Absolute number Total Malignant Accidents Suicide Homicide Cerebrovascular disease Aids Liver disease Congenital conditions CLRD Poisoning, undetermined intent Benign/other Diabetes Flu/pneumonia Viral hepatitis Psychoactive substance abuse Other causes Leading causes of death in Israel,

24 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Males Cause of death Rate per 100,000 population Total Malignant Diabetes Suicide Accidents Cerebrovascular disease Kidney disease CLRD Liver disease Flu/pneumonia Hypertension Psychoactive substance abuse Homicide (2.6) Benign/other (2.4) (1.9) (3.0) (2.9) (2.4) (2.1) 2.8 (2.6) (2.3) 16 Viral hepatitis (2.8) 4.5 (2.1) (2.3) 17 Poisoning, undetermined intent (3.0) (1.7) (1.6) (2.3) 18 Other causes Absolute number Total 3,165 3,328 3,273 3,381 3,412 3,384 3,424 3,661 3,573 1 Malignant 1,019 1,116 1,103 1,131 1,162 1,219 1,268 1,306 1, Diabetes Suicide Accidents Cerebrovascular disease Kidney disease CLRD Liver disease Flu/pneumonia Hypertension Psychoactive substance abuse Homicide Benign/other Viral hepatitis Poisoning, undetermined intent Other causes Ministry of Health, Israel

25 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Females Cause of death Rate per 100,000 population Total Malignant Diabetes Cerebrovascular disease CLRD Kidney disease Accidents Suicide (1.5) Liver disease 3.8 (2.1) (1.9) (2.5) (1.9) 2.9 (2.3) 2.6 (2.4) 11 Hypertension (2.6) (1.6) (2.5) (1.3) (2.1) (1.9) (1.9) 12 Benign/other (2.4) (1.9) (1.3) (2.0) (2.3) (2.1) (2.1) 2.7 (1.5) 13 Flu/pneumonia (2.1) (1.9) (1.3) (1.6) (2.1) (2.0) (1.3) מפרצת באב העורקים 14 (1.0) (0.7).. (0.9) (1.0) 15 Homicide (0.9) (1.5) (0.7).. (1.1) (1.2).. (1.3) (0.9) 16 Viral hepatitis (1.4) (1.6) (1.6) (1.4) (1.8) (1.6) (1.3) (1.0) (0.9) 17 Congenital conditions.. (1.3) (1.5) (1.1) (1.0).. (1.8) (1.2) (0.8) 18 Other causes Absolute number Total 2,041 2,079 1,993 2,154 2,192 2,217 2,197 2,295 2,150 1 Malignant 1,069 1,143 1,118 1,218 1,211 1,263 1,271 1,256 1, Diabetes Cerebrovascular disease CLRD Kidney disease Accidents Suicide Liver disease Hypertension Benign/other Flu/pneumonia מפרצת באב העורקים Homicide Viral hepatitis Congenital conditions Other causes Leading causes of death in Israel,

26 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Males Cause of death Rate per 100,000 population Total Malignant Diabetes Cerebrovascular disease Kidney disease CLRD Flu/pneumonia Accidents Liver disease Hypertension Suicide (12.6) (11.2) (11.2) Pnemonitis due to solids and liquids (12.6) (7.9) Dementia (11.9) (4.2) (4.2) (5.9) (9.4) (8.6) Benign/other (11.3) (10.0) 10.0 מפרצת באב העורקים 16 (8.6) (10.8) 12.5 (9.4) (8.2) (8.4) (9.0) 17 Parkinson s disease (9.3) (9.6) 14.3 (10.6) (10.0) (10.3) (8.9) (4.7) (8.0) 18 Other causes Absolute number Total 4,040 3,714 3,618 3,738 3,464 3,404 3,470 3,485 3,731 1 Malignant 1,282 1,197 1,255 1,264 1,230 1,213 1,269 1,213 1, Diabetes Cerebrovascular disease Kidney disease CLRD Flu/pneumonia Accidents Liver disease Hypertension Suicide Pnemonitis due to solids and liquids Dementia Benign/other מפרצת באב העורקים Parkinson s disease Other causes Ministry of Health, Israel

27 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Females Cause of death Rate per 100,000 population Total Malignant Diabetes Cerebrovascular disease Kidney disease CLRD Accidents Flu/pneumonia Hypertension Liver disease (9.2) Dementia (8.3) (4.9) (3.4) (5.8) 10.7 (4.3) Parkinson s disease (7.2) (7.8) (6.8) (7.3) (2.4) (4.8).. (5.8) Benign/other 17.1 (9.3) (6.3) (8.7) (9.2) 10.5 (8.0) 12.6 (6.8) 15 Alzheimer s disease (8.3) (6.8) (7.3) (8.7) (7.8) (4.8) (3.3) (7.2) (6.8) 16 Viral hepatitis (7.2) (6.3) (6.8) (6.7) (3.3) (6.7) (6.0) 17 Suicide (7.8) (4.9) (2.4) (3.9) (4.4) (2.9) (6.6) (3.6) (4.7) 18 Other causes Absolute number Total 3,356 2,858 2,849 2,747 2,653 2,506 2,546 2,551 2,683 1 Malignant 1,108 1,067 1,058 1,009 1, ,091 1,008 1, Diabetes Cerebrovascular disease Kidney disease CLRD Accidents Flu/pneumonia Hypertension Liver disease Dementia Parkinson s disease Benign/other Alzheimer s disease Viral hepatitis Suicide Other causes Leading causes of death in Israel,

28 Tables: Leading causes of death by year Leading causes of death by underlying cause and year, Absolute numbers and rates/100,000 population Age Males Cause of death Rate per 100,000 population Total Malignant Cerebrovascular disease Kidney disease Diabetes CLRD Flu/pneumonia Dementia Accidents Hypertension Pnemonitis due to solids and liquids Alzheimer s disease Parkinson s disease Benign/other Liver disease Anemias Other causes Absolute number Total 9,830 10,458 10,380 10,950 10,838 10,677 11,026 11,381 11,870 1 Malignant 1,932 2,273 2,203 2,328 2,346 2,364 2,438 2,485 2, ,562 2,411 2,331 2,578 2,334 2,298 2,341 2,305 2,178 3 Cerebrovascular disease Kidney disease Diabetes CLRD Flu/pneumonia Dementia Accidents Hypertension Pnemonitis due to solids and liquids Alzheimer s disease Parkinson s disease Benign/other Liver disease Anemias Other causes 1,676 1,762 1,770 1,914 1,898 1,837 1,865 1,934 2, Ministry of Health, Israel

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