Dealing with Obesity Concurrent Diseases Hill s Global Symposium Proceedings

Transcription

1 Dealing with Obesity Concurrent Diseases 2015 Hill s Global Symposium Proceedings

2 Feline Urinary Disease Obesity

3 Hill s Prescription Diet Metabolic + Urinary Feline Todd L. Towell, DVM, MS, DACVIM President, Global Veterinary Consulting Erie, Colorado Heather Berst, VMD Hill s Pet Nutrition Topeka, KS The Challenge Which Nutritional Recommendation: LUTS Or Obesity? Studies confirm that Hill s Prescription Diet c/d Multicare Feline is the best choice for managing two of the most common causes of lower urinary tract signs (LUTS) in cats, feline idiopathic cystitis (FIC) and struvite urolithiasis. For cats with FIC, a multimodal approach that includes environmental enrichment as well as dietary management is recommended. The best currently available evidence is for dietary management with Hill s Prescription Diet c/d Multicare Feline dry food. 1 In a year-long randomized controlled clinical study of cats with naturally occurring FIC, cats consuming c/d Multicare dry food had significantly fewer episodes of FIC signs (p < 0.05) than cats eating a control food. Investigators concluded that consistent feeding of c/d Multicare to cats with FIC resulted in an 89% reduction in the rate of recurrent episodes of FIC signs (Figure 1). This is the first study to definitively demonstrate the impact of a food on the expression of FIC signs in cats. For cats with struvite uroliths, medical dissolution is generally the primary goal of therapy. Since first described in 1983 dietary dissolution of struvite uroliths has been recognized as safe and effective. 2-4 A recently published study documents that struvite stones dissolved in as little as Consistent feeding of c/d Multicare to cats with FIC resulted in an 89% reduction in the rate of recurrent episodes of FIC signs. This is the first study to definitively demonstrate the impact of a food on the expression of FIC signs in cats. 1 [ 73 ]

4 Episodes per 1000 study days A recently published study documents that struvite stones dissolved in as little as 7 days (mean 27 days) when cats were fed Hill s Prescription Diet c/d Multicare Feline dry food (Figure 2) Control Food (n=14) 89% Reduction in Rate 1.3 c/d Multicare (n=11) Figure 1. An 89% reduction in the rate of recurrent episodes of FIC signs was seen in cats fed c/d Multicare compared with control-fed cats. 6 s/d 28 13±2.6 P= c/d MC 52 27± Days Figure 2. Struvite dissolution times. 7 days (mean 27 days) when cats were fed Hill s Prescription Diet c/d Multicare Feline dry food (Figure 2). 5 While medical dissolution of calcium oxalate uroliths, the second most common urolith in cats, is not currently possible, results of a recent study suggest nutritional management is important for reducing recurrence. 6 Results of this 2-year-long study of cats with naturally occurring calcium oxalate stones suggest that recurrence of calcium oxalate uroliths may be lower in cats fed Hill s Prescription Diet c/d Multicare. Obesity is another common health issue in cats. Since its introduction, Hill s Prescription Diet Metabolic Advanced Weight Solution has been helping overweight and obese cats to return to a healthy weight. Pet owners agreed that this diet, formulated with a synergistic blend of natural ingredients shown to activate metabolism, is an effective way for their pets to lose weight while keeping their pets feeling full and satisfied. This success may be due in part to the diet s positive impact on energy metabolism during weight loss and maintenance, which results in reduced body fat and increased lean body mass in cats. 7,8 By increasing energy metabolism during weight loss, this diet allows pets to successfully lose weight. Prescription Diet Metabolic can be fed for both weight loss and weight maintenance, making it a perfect solution for multi-cat households. One Nutritional Solution For Two Common Conditions. The introduction of Hill s Prescription Diet Metabolic + Urinary offers the veterinary health care team a new option with the power of AND. Metabolic + Urinary combines the benefits of two proven nutritional solutions, Hill s [ 74 ]

5 LUTS with Normal BCS c/d Multicare c/d Multicare Stress Figure 3. Nutritional solutions. Prescription Diet Metabolic Advanced Weight Solution and Hill s Prescription Diet c/d Multicare. Now there is one food with clinically proven nutrition to manage obesity and the common causes of LUTS. Formulated with a synergistic blend of natural ingredients shown to activate metabolism and help cats lose weight as well as both high levels of omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and antioxidants to help break the cycle of inflammation in patients with FIC, Metabolic + Urinary is the one nutritional solution for overweight cats with lower urinary tract signs. For feline patients it is now easier than ever before to customize a specific nutritional solution for the unique circumstances of each pet (Figure 3). Summary: The Power Of And The introduction of Hill s Metabolic + Urinary provides pets, pet owners, and the veterinary health care team with a sophisticated yet simple nutritional option for managing some of the most common concurrent conditions in feline veterinary medicine. Overweight Metabolic Advanced Weight Solution OW AND LUTS Metabolic + Urinary References 1. Kruger JM, Lulich J, Merrills J, et al. A year-long prospective, randomized, double-masked study of nutrition on feline idiopathic cystitis. Proceedings of the American College of Veterinary Internal Medicine Annual Forum, Osborne CA, Lulich JP, Kruger JM, et al. Medical dissolution of feline struvite urocystoliths. J Am Vet Med Assoc 1990;196: Houston DM, Rinkardt NE, Hilton J. Evaluation of the efficacy of a commercial diet in the dissolution of feline struvite bladder uroliths. Vet Ther 2004;5: Houston DM, Weese HE, Evason MD, et al. A diet with a struvite relative supersaturation less than 1 is effective in dissolving struvite stones in vivo. Br J Nutr 2011;106 Suppl 1:S Lulich JP, Kruger JM, Macleay JM, et al. Efficacy of two commercially available, low-magnesium, urine-acidifying dry foods for the dissolution of struvite uroliths in cats. J Am Vet Med Assoc 2013;243: Lulich J, Kruger JM, MacLeay J, et al. A two year long prospective, randomized, double-masked study of nutrition on the recurrence of calcium oxalate urolithiasis in stone forming cats. ACVIM Annual Forum, Jewell DE, Floerchinger AM, Jackson M, et al. A reduced calorie, high fiber food with added coconut oil, L-carnitine, lysine and leucine increases basal metabolic rate in overweight and obese cats (Abstract). J Vet Intern Med 2014;28: Jewell DE, Floerchinger AM, Jackson M, et al. A reduced calorie, high fiber food with added coconut oil, L-carnitine, lysine and leucine increases basal metabolic rate in overweight and obese dogs. J Vet Intern Med 2014; Metabolic + Urinary Feline combines the benefits of two proven nutritional solutions, Hill s Prescription Diet Metabolic Advanced Weight Solution and Hill s Prescription Diet c/d Multicare. Now there is one food with clinically proven nutrition to manage obesity and the common causes of LUTS. [ 75 ]

6 OBESITY + FLUTD Let s treat them together REDUCES BODY WEIGHT BY 11% IN 60 DAYS1 REDUCES THE RECURRENCE OF FIC SIGNS BY 89%2 NEW PRESCRIPTION DIET Metabolic+Urinary Meet the world s only proven single solution for both. Together we can help all of your patients at risk. For more information, talk to your Hill s Representative. Data on file. Hill s Pet Nutrition, Inc. Kruger JM, Lulich JP, Merrils J, et al. Proceedings. American College of Veterinary Internal Medicine Forum Hill s Pet Nutrition, Inc. / Trademarks owned by Hill s Pet Nutrition, Inc. 1 2 HillsVet.com