Smart packaging for medicine adherence:
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- Job Atkinson
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2 Smart packaging for medicine adherence: Use, technological building blocks and applications Corné Rentrop
3 Smart Packaging Smart packaging: Connected world Customer engagement Security
4 Connected packaging.. MLA DELIVERS WEATHER BASED RECIPES for customer adherence (?)
5 The internet of everything
6 Example: Smart Blister Smart packaging for medicine adherence Corné Rentrop
7 Smart Medical Blisters Features Simple All electronics in footprint blister Printed resistance ladder Monitor when en what pill is pushed through NFC communication
8 Therapy Compliance Non-Compliant patient, (red bar forgotten black arrow double doses red dots out of the time window ). Glucose value too high when pill is not taken on time.
9 E-communicative packaging for pharma Smart pill blister addresses key health issue: medication non-compliance / non-adherence Developed jointly with DSM/TCG Smart blisters Patient Medical devices GSM/GPRS wireless network Support centre RFID/NFC DataGator GSM/GPRS wireless network
10 Smart Challenges Label: Environmental of smart blister monitoring The Holst approach Holst Centre System in Foil e.g. StoraEnso Pharma DDSi Features: Assembled 3D -system High cost Added to existing package, not compatible with R2R Near Future: Fully integrated 2D-System in Foil Low cost, mass fabrication Roll to Roll compatible
11 Other Examples. Corné Rentrop
12 Smart label: Integration on paper Smart tag Humidity sensor Temperature sensor NFC Smart label: Temperature, humidity sensor Data storage NFC enabled
13 Use cases: Report Max./Min. temperature and humidity during transport Actual temperature and humidity App assisted
14 Smart packaging Smart label: Foil integration Temperature and ammonia sensor Ultrathin chip
15 Smart Packaging: Track and trace envelope Envelope Track and trace Antenna 300m Chip Password control Web-acces Printed registered mail 300 m communication Password control Web-access Embossed switches
16 Smart Packaging: Track and trace envelope Envelope Track and trace Antenna 300m Chip Password control Web-acces Electronic lay-out Screen printing Roll-to-roll (up to 20m/min.) Flash sintered Component integration
17 Smart envelope track and trace Wireless communication Electronic layout Envelope Design Antenna performance Web access and security
18 .. or can that even can be shapedinto a 2.5D 3D surface objects
19 or PCB s stretchable that are stretchable
20 t packaging helve: ure sensors in series ge management ess communicating net of things
21 Smart Label: Environmental monitoring How to create smart packaging? Corné Rentrop
22 Components
23 Multi disciplinary approach Substrate Graphical industry Electronics/ logic Printing/ inks Placing components Sensors
24 Screen printing: resolution routinely print 30 µm line and spacing (60 µm pitch) (first steps towards 20 µm line and spacing)
25 Holst Centre Inkjet printing 15 µm line / spacing achievable
26 Sensing platform: interdigitated fingers Printed Thermistor Printed H2S sensor Printed humidity sensor Interdigitated finger structure monitors: Temperature Humidity Gasses (H 2 S)
27 Sensing platform: Switches Chip pad Antenna Switch Sensor Printing of electrical components: Switch Antenna Chip pad
28 Holst Centre Electronic components: Pick and place Smart tag Humidity sensor Temperature sensor NFC Paper sensor tag: Chip (NFC) Antenna Sensor platform
29 Summary Components
30 Final remarks - Component integration - Antenna - Chip - NFC - Sensor - Applications: - Smart packaging - Wearables - Human machine interfaces - Printed sensors - ECG, EMG, EEG.. - Temperature - Gas (H 2 S) - Humidity
31
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