Investing in Incubation A View from Stevenage Bioscience Catalyst (SBC)

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1 Investing in Incubation A View from Stevenage Bioscience Catalyst (SBC) Miranda Knaggs, Business Manager You re smart. We care. Join a community making a difference...

2 Building a world class Open Innovation Pharma Campus A national asset for UK life sciences 60,000 sq ft of wet lab & office space Co-located with GSK s 2,500 R&D scientists in Stevenage Accelerating the development and commercialisation of opportunities in the pharma and medtech space.

3 In addition to the traditional incubator metrics. Facilitating early academic engagement with industry

4 Open Innovation in Action SBC doesn t do open innovation..it is open innovation The key to achieving this comprehensive vision was to build not only an attractive campus, but an exciting scientific and commercial environment which would ultimately attract international interest and multiple pharma involvement. TIGHT CONTROLS Vision alignment (board, CEO, management team, tenants) IP generation (80%) Quality science (tenant selection) Spaces ( OI is a contact sport ) LOOSE CONTROLS Network development - external search and internal connectivity Business model evolution Partnerships Promotes entrepreneurialism

5 The SBC Science Centred Business Model Science (Idea) Originating wrapper (University / Commercial) Fast-fail DA GSK Experts Panel OI Science Incubation Focus on Science Business Incubation Temporary wrapper Valued Science New commercial wrapper EiR LBS Legal Funding LOCATE RELOCATE DEVELOP EXIT REPEAT & LEARN valuable scientific outcomes deliver business success & ecosystem growth Chris Ford, March

6 Progress since 2012 Tenancy Open Innovation OI KPIs/Metrics Now over 170m of investment raised by our tenants 7 Cambridge and UCL projects based at SBC Inward investment tenants from Japan, US, Australia, Spain, Greece 4 successful OI summits First OI challenge in Neurodegenerative diseases launched Discover Assist working with 17 Universities across the UK and Europe 3 other pharma presence on campus 96% of tenants rank SBC incubator support as critical or important in their development 80% of the tenants are IP/research focussed 16 of the tenants are working with GSK 14 of the tenants are working in the GE Technology Lab Tenant to tenant collaboration deals being signed You re smart. We care. Join a community making a difference...

7 SBC Tenants Therapeutics

8 SBC Tenants Devices/Diagnostics

9 SBC Tenants Manufacturing/Technology

10 SBC Tenants Big Data/Analytics

11 SBC Tenants Corporate Members

12 SBC Tenant Investors (x4) (x2) Apollo Therapeutics

13 Apollo Therapeutics office based at SBC The 40 million fund, launched in January 2016, will drive forward therapeutic innovation with the goal of significantly improving the speed and potential of university research being translated into novel medicines. It is a unique collaboration between AstraZeneca, GlaxoSmithKline, Johnson & Johnson Innovation, and the technology transfer offices of Imperial College London, University College London and the University of Cambridge, and is the first time that global pharmaceutical companies and worldleading universities have come together to create this type of fund.

14 Preparing for Phase 2 The Immediate Future and Beyond Incubator at maximum capacity and Tenants seeking grow-on Starting Convergence agenda now (Deal flow) MRCT arrived April 2016 Accelerator ground floor for additional tenancy Cell & Gene Therapy Catapult opening 2017 Growing relationship with other pharma PHASE 2 MUST START QUICKLY = CONTINUE THE MOMENTUM You re smart. We care. Join a community making a difference...

15 SBC Campus Today You re smart. We care. Join a community making a difference...

16 Investment Challenges Expectation was never to go back to the stakeholders for more money Public purse strings are being tightened and innovation not as high on gov agenda ROI to property developers is very low and very long term game and therefore of little interest Other strategic partners?

17 Thank you for listening Our vision and mission statement Catalysing innovation by exploring new ways of collaboration To transform innovative ideas into commercial reality, we will seek out the best ideas and talent and create a world class environment that stimulates creativity and encourages new open and collaborative ways to deliver health care solutions that make a difference to patients' lives. You re smart. We care. Join a community making a difference... Come and talk to us Page 3 You re smart. We care. Join a community making a difference...

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