Leader in White Biotech Solutions Competence to take you ahead. engineering for a better world

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1 Leader in White Biotech Solutions Competence to take you ahead engineering for a better world

2 White Biotech industrial production of the future For the last three decades industrial biotechnology has seen stunning advances earlier generations could not have envisaged. But we are still only at the beginning of the White Biotech revolution, one that will change the face of production industries forever. New bioeconomical solutions for energy, chemical production, bioplastics and pharmacy are on their way in to set new standards in mass production. Just in time, as the corresponding demands for a sustainable global economy have moved into the social spotlight worldwide. From a fossil-based towards a bioeconomically based industry the innovation cycle keeps accelerating. For thousands of years, ancient societies have known the use of complex biotechnical processes in beer, wine, cheese and leather production, among other applications, but without understanding these processes. This has changed with the discovery of enzyme functions and the fermentation process over the last centuries, and with the breathtaking progress in the decoding of microorganism genomes and in controlling the genetic mechanism during our own time. Thus, mass products that are essential for present societies can today be produced with important functional advantages, and with greatly reduced amounts of heat, pressure and harmful by-products in the production process: Cleaning agents, biofuels, many bulk chemicals as well as fine chemical products such as food additives and nutritional supplements. However, in many application areas, developments have only just begun. New research must lay the foundations for a truly efficient means of production, to which biotechnology can make a decisive contribution. More and even greater possibilities have already been discovered and studied in tests. Biorefineries and biomass-to-fuel processes are just two technologies on the verge of becoming standard tools of modern production. And thousand of yet unexplored microbe varieties with special properties and functional opportunities remain to be studied, while, at the engineering frontier, entirely new approaches to synthetic bio design are being developed. Comprehensive studies and analyses on the potential of industrial biotechnology all foresee substantially growing proportions of biotechnological methods in chemical manufacturing, for the near future as well as in long-term perspective. The race is on for tomorrow s success in industrial production. Highly functional plastic materials are a key product of innovative White Biotech manufacturing processes. Towards a bioeconomically based production: White Biotech produces high-value products from low-value plant materials (stem and leaf cells, cellulose, ).

3 GEA Leader in White Biotech solutions The commercial application of the latest advances in bioengineering requires an equally advanced standard of process technology solutions. Successful upscaling of test processes to industrial levels is one challenge to be met. Others are the combination of different process steps in plant designs, and reliable quality control on an industrial scale. Offering the competencies of highly experienced process technology specialists in one structured portfolio, GEA is the go-to address for producers when it comes to meeting these challenges. From the upstream and fermentation process stage in GEA technology will take place with absolute to numerous special applications in the decisive reliability of delivery and future service ensured. Contact our representatives in your region for your customized White Biotech solutions! downstream phases, GEA combines expertise and ready-to-work, future-oriented solutions that will GEA specialists work hand in hand to make solution make system users reach their goals. shortcuts and functional benefits possible that can not be obtained from separate providers. Both leading expertise and leading technology solutions from GEA are available around the Future-oriented biotech systems competence world. GEA is one of the largest system providers Specialists working hand in hand for of machines and process technology worldwide, a market and technology leader in about 90 percent of its business areas. maximum process benefits Customized White Biotech engineering and solutions worldwide Test centers for testing single process GEA has companies and service contacts in every world region, many of them specialists in White Biotech. The strong corporate and financial resources in the GEA Group mean that any investment steps or process combinations at GEA or customer sites Corporate and financial strength in the global GEA Group We are at your service, for maximum results Reliability, efficiency and budget control over In other words: You benefit from the long ex- the entire life cycle perience of GEA Group as a technology leader in equipment and solutions. Our focus is always on GEA Group offers its customers a comprehensive the achieved overall benefit for the customer over service concept, in which experts with manu- the entire life cycle. facturing know-how and up-to-date knowledge optimally care for every single GEA equipment Keys to manufacturing success component. Maximum plant availability Permanently high equipment and process efficiency Absolute budget control for optimized TCO

4 Liquid jet solid pumps, liquid jet mixers Direct steam injection Liquid jet pumps Technology solutions from GEA in the upstream, fermentation and downstream process Whatever your White Biotech process, international GEA specialists work together to create maximum benefit solutions for you, delivering the right process technology components in ideal combinations, tailored to your process. Substrate Mixing Sterilization Dosing Supplements Upstream Centrifugal separation, membrane filtration Membrane filtration, crystallization, distillation Membrane filtration, crystallization, distillation Membrane filtration, freeze concentration, evaporation Crystallization Drying Powder handling & packaging Pure culture Propagation Fermentation Fermenter design Biomass separation isolation purification concentration crystallization drying & confectioning handling & packaging In-place cleaning & sterilization Aeration & agitation Heating & cooling Measuring & control Sidestream concentration Drying & confectioning Downstream Fermenter equipment Liquid jet gas compressors, liquid jet mixers Steam jet cooling, steam jet heaters Process control systems Fermentation tanks, piping, valve matrix, pumps Biomass concentration Biomass drying Evaporation Drying Evaporation Crystallization

5 Key areas of White Biotech expertise in the global GEA Group Focusing on demanding and sophisticated production processes, GEA offers efficient and flexible solutions for customers in the White Biotech sector advancing both environmental sustainability and economic benefit. Evaporation by GEA Kestner and GEA Wiegand Centrifugal Separation by GEA Westfalia Separator Group Falling film evaporation Forced circulation evaporation Tubular or plate design, single- or multi-effect Vapour recompression heating concepts (MVR, TVR) Energy-optimized, tailor-made solutions specific testing at own test lab and on site Disk separators Decanter centrifuges for biomass separation and extraction Customized centrifuge systems and package units specific testing at own test labs and at site Membrane Cross Flow Filtration by GEA Filtration Drying by GEA Niro and GEA Barr-Rosin Microfiltration Ultrafiltration Nanofiltration Reverse osmosis Skid-mounted Fully automated, tailor-made specific testing at own test lab and on site Flash dryers and coolers Fluid bed dryers and coolers Freeze dryers Ring dryers Paddle dryers and coolers Spray dryers Distillation Process Solutions by GEA Wiegand by GEA Liquid Processing Distillation and rectification plants Pressure swing adsorption Tray and packed columns Pressure-vacuum multi-column systems Vapour recompression heating concepts (MVR, TVR) Energy-optimized, tailor-made solutions Project management Process turnkey projects Media preparation Process integration Fermentation Mixing technology Automation Crystallization by GEA Messo PT and GEA Kestner Powder Handling & Packaging by GEA Avapac and GEA Nu-Con Solution & melt crystallization, freeze concentration Meeting your specific requirements (e.g. product purities, crystal size) Range of crystallizers: FC, DTB, oslo, surface cooling Energy integration & optimization systems: MVR, TVR, heat pumps, multi-effect Crystal separation Rotary valves Powder handling & storage Bulk packing 25 kg bag filling Retail filling

6 We live our values. Excellence Passion Integrity Responsibility GEA-versity GEA Group is a global engineering company with multi-billion euro sales and operations in more than 50 countries. Founded in 1881, the company is one of the largest providers of innovative equipment and process technology. GEA Group is listed in the STOXX Europe 600 Index. GEA Avapac GEA Barr-Rosin GEA Filtration GEA Kestner GEA Liquid Processing GEA Messo PT GEA Niro GEA Nu-Con GEA Westfalia Separator Group GEA Wiegand white-biotech@gea.com GEA Group AG. All rights reserved. Subject to modifications. Printed in Germany. B_CP EN

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