Distance Learning in Graduate Courses Applications and Tools in Pharmaceutical Chemistry
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1 ChemEd 201 Distance Learning in Graduate Courses Applications and Tools in Pharmaceutical Chemistry Oliver Grundmann Department of Medicinal Chemistry, College of Pharmacy, University of Florida, U.S.A; More about the Gator Nation 4th Largest University in the Nation Major Public Research University Over 50,000 enrolled students Long history of joint programs with international institutions Member of the Association of American Universities One of a select few public universities with this distinguished honor Oliver Grundmann, 1
2 ChemEd 201 Targeting the non-traditional student and working professional Metabolism Business & Management Laboratory QA & QC Natural Medicinal Products MS program in Pharmaceutical Chemistry Curriculum for Masters of Science in Pharmaceutical Chemistry Credits Principles of Pharmaceutical Chemistry 1 Principles of Nucleotide Activity 2 Special Topics in Pharmaceutical Chemistry 1 Mammalian Pharmacology 4 Drug Biotransformation & Molecular Mechanisms of Toxicity Metabolic Biochemistry Pharmaceutical Chemistry 1 Pharmaceutical Chemistry 2 Natural Medicinal Products/Herbal & Dietary Supplements Synthetic Medicinal Chemistry/Introduction to Medical Bioethics Pharmaceutical Analysis 2/Organic Structure Elucidation Introductory/general courses Pharmacology/ Metabolism Medicinal Chemistry Pharmaceutical Analysis Laboratory QA/QC Total credits Oliver Grundmann, 2 2
3 ChemEd 201 Program Success Course enrollments for Forensic Sciences and Pharmaceutical Chemistry Distance Education Programs Enrollment Student Nationalities ANTARTICA AUSTRALIA BERMUDA BOSNIA HERZEGOVINA BRAZIL BAHAMAS CANADA CHILE CHINA COLOMBIA ECUADOR FRANCE TARTICA GREENLAND ICELAND IRELAND ITALY JAPAN JAMAICA MALTA NEW ZEALAND NETHERLANDS SOUTH AFRICA SRI LANKA SWITZERLAND THAILAND TRINIDAD UNITED KINGDOM UGANDA Oliver Grundmann,
4 ChemEd 201 Focus: Pharmaceutical Industry Designed for students and professionals working in: Drug development Preclinical pharmacology & toxicology QA/QC department Regulatory affairs & drug policy Tailored for Chemistry, Biochemistry and Biology majors interested in advancing their knowledge and career Program offers an avenue for students and working professionals worldwide to take graduate coursework or continuing education while on the job Value to employers and employees World Class online degree and courses from the highly renowned University of Florida Convenient way for students and professionals to continue their education and enhance career options Retain your workforce Optimize your educational needs Offer advanced degrees to your employees Tailor continuing education and areas of interest Flexible, asynchronous course schedule does not interfere with work responsibilities Oliver Grundmann, 4
5 ChemEd 201 LMS platform - Sakai Course Examples Sakai platform Oliver Grundmann, 5
6 ChemEd 201 Course Examples animations and interactions Medicinal Chemistry TLC and HPLC Mobile phase in HPLC Adobe Connect for synchronous chat sessions Oliver Grundmann, 6
7 ChemEd 201 Principles of Pharmaceutical Chemistry Graduate course: Principles of Pharmaceutical Chemistry Abstract concepts require the use of multidimensional instructional tools Flash animations Forum discussions Chat sessions Narrated power point slides Problem: encourage independent thinking skills beyond simple comprehension and application of acquired knowledge (transfer problem) Integration of HyLighter Solution: HyLighter HyLighter assignment required students to A) Apply and transfer knowledge learned throughout the class to a novel problem setting B) Context-related acquisition of knowledge through association of resources C) Peer review and self-reflection Oliver Grundmann, 7
8 ChemEd 201 HyLighter HyLighter is an online tool that allows collaboration of a group to work on a document Highlights can be added to text, graphics, and structures and commented on Collaborative approach provides for a visually enhanced learning experience All participants can connect the different parts of a case by linking fragments of content and related discussion threads within and between documents and related resources (e.g. reference articles, HTML pages, and uploaded documents) HyLighter creates a truly collaborative approach which translates from a case study into the real world Case study in HyLighter Students were tasked to first individually answer questions presented to them in HyLighter Case study presented was the drug development process for a new antihypertensive drug (labetalol) Students had to apply concepts learned during the class to answer questions, including: Derive physicochemical properties (solubility, logp, degree of ionization, pk a ) Identify functional groups (acidity and basicity, influence on lipophilicity) Deduce structural relationship with activity Apply concepts of pharmacodynamics and pharmacokinetics Identify partial structures for metabolic pathways Oliver Grundmann, 8
9 ChemEd 201 Integration of HyLighter Integration of HyLighter Oliver Grundmann, 9
10 ChemEd 201 Integration of HyLighter Integration of HyLighter Oliver Grundmann, 10
11 ChemEd 201 Integration of HyLighter Learning outcomes and benefits Connecting the dots Effective tool to transfer acquired knowledge into practical and authentic scenarios. Self-evaluation and comparison provided additional discussion incentives and increased engagement. Collaborative student approaches complemented quizzes and individual assignments. Oliver Grundmann, 11
12 ChemEd 201 Further program information Websites Pharmaceutical Chemistry Forensic Sciences Oliver Grundmann Ian Tebbett, Program Director Oliver Grundmann, 12
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