CASE 04/04/2016 CUT THRU EVERY LOCULE AND SAMPLE ANYTHING THAT LOOKS DIFFERENT GROSS EXAM: SAMPLE, SAMPLE, SAMPLE

Size: px
Start display at page:

Download "CASE 04/04/2016 CUT THRU EVERY LOCULE AND SAMPLE ANYTHING THAT LOOKS DIFFERENT GROSS EXAM: SAMPLE, SAMPLE, SAMPLE"

Transcription

1 CASE 22 YOF G2P1 SVD US: LARGE COMPLEX OVARIAN MASS WITH NODULAR COMPONENT LFU; ADMITTED TO ER WITH SEVERE ABDOMINOPELVIC PAIN EXPLOR LAP LARGE CYST FILLED ABDOM/PELVIS RUPTURED AT REMOVAL & SPILLED 7500 cc INTO PELVIC CAVITY GROSS EXAM: SAMPLE, SAMPLE, SAMPLE RUPTURED TUMOR MEASURED 17.0 x 16.3 x 4 cm PAUCILOCULAR TUMOR (white arrows & ellipse) SPONGY MURAL NODULE 4.0 x 2.5 x 1.5 cm (black arrows) CUT THRU EVERY LOCULE AND SAMPLE ANYTHING THAT LOOKS DIFFERENT 1

2 MUCINOUS BORDERLINE TUMOR WITH FOCAL BORDERLINE MICROINVASION IN A 22 YO POSTPARTUM PATIENT MUCINOUS BORDERLINE TUMOR IN A 22 YO POSTPARTUM PATIENT 22 YOF WITH MBOT AND MIV MBOT MUCINOUS BORDERLINE TUMOR WITH MICROINVASION (BLMIV) 2

3 MBOT WITH MIV MBOT WITH MICROINVASION VS MICROINVASIVE CARCINOMA FAQ: WHAT ARE THE TYPES OF MICROINVASION IN MBOTs? 3

4 CONFLUENT (EXPANSILE) MICROINVASIVE MUCINOUS CARCINOMA OVARIAN TUMOR WITH MICROINVASIVE MUCINOUS ADENOCARCINOMA PRIMARY OVARIAN MUCINOUS CYSTADENOMA 4

5 OVARIAN MUCINOUS CYSTADENOMA, GI TYPE MUCINOUS BORDERLINE OVARIAN TUMOR LOADING DOCK SCALE 102 LBS 30 YOF MUCINOUS BORDERLINE OVARIAN TUMOR 30 YOF 5

6 MUCINOUS BORDERLINE OVARIAN TUMOR 30 YOF MUCINOUS BORDERLINE OVARIAN TUMOR WITH FOCAL INTRAEPITHELIAL CARCINOMA 30 YOF MUCINOUS BORDERLINE TUMOR (UPPER VILLUS) AND INTRAEPITHELIAL CARCINOMA (LOWER VILLUS) 6

7 MUCINOUS BORDERLINE TUMOR W/ INTRAEPITHELIAL CARCINOMA 16 YOF BORDERLINE OVARIAN TUMORS, GI (L) AND SEROMUCINOUS TYPES SEROMUCINOUS OVARIAN BORDERLINE TUMOR (MULLERIAN ENDOCERVICAL TYPE) 7

8 SEROMUCINOUS BORDERLINE OVARIAN TUMOR Immunohistochemical Findings of a Panel of IHC Markers in OMNs and Metastatic Colorectal Adenocarcinomas in the Ovary. Lin X et al. (Appl Immunohistochem Mol Morphol 2008;16: ) Neoplasm CDX-2 (%) CA-125 (%) CK7 (%) CK20 (%) No. Intestinal type OMN Endocervical-like OMN Colorectal adenoca WELL DIFFERENTIATED OVARIAN MUCINOUS ADENOCARCINOMA 8

9 UNICYSTIC MUCINOUS ADENOCARCINOMA OF THE OVARY MET COLON CA TO OV HOW OFTEN ARE PRIMARY OVARIAN MUCINOUS TUMORS BILATERAL? RARELY! CLX CASE: 54 YOF BILATERAL OVARIAN TUMORS EACH ~1.2 KG CONSULT:? MBOTs PRIOR PANCREATIC RESECTION FOR 8 CM CYSTIC INTRADUCTAL PAPILLARY NEOPLASM AND 2 MM OF CYST WALL INVASION 9

10 UNILATERAL OVARIAN MUCINOUS TUMOR IN A 68 YOF METASTATIC COLON CA TO OVARY SIMULATING PRIMARY MUCINOUS TUMOR ENDOMETRIOID CARCINOMA OF THE COLON ENDOMETRIOID COLON CARCINOMA 10

11 COLON ADENOCARCINOMA WITH CLEAR CELL CHANGE CK 7- Metastatic intestinal carcinomas simulating primary ovarian clear cell carcinoma and secretory endometrioid carcinoma: a clinicopathologic and immunohistochemical study of five cases. Am J Surg Pathol CK 20+ CDX2+ PSEUDOMYXOMA PERITONEI PRIMARY APPENDICEAL MUCINOUS TUMOR WITH OVARIAN AND OMENTAL METASTASES APPENDICEAL MUCOCELE (arch.) CONTAINING GLAIRY MUCUS 11

12 PRIMARY APPENDICEAL MUCINOUS TUMOR WITH METASTASES TO RIGHT OVARY PRIMARY APPENDICEAL MUCINOUS TUMOR WITH METASTASES TO RIGHT OVARY OVARIAN METASTASIS FROM APPENDICEAL PRIMARY LAMN 12

13 TOO TALL ET AL. LAMN & PMP APPX LAMN WITH PUSHING INVASION AND RUPTURE 13

14 PMP DERIVED FROM LAMN Am J Surg Pathol 2016;40:14 26 HOW TO PSIGN OUT PSEUDOMYXOMA PERITONEI MUCINOUS ASCITES ORGANIZING MUCINOUS ASCITES DISSECTING MUCIN WITH FIBROSIS CLASSIFICATION OF PMP MUCIN WITHOUT EPITHELIAL CELLS: ACELLULAR MUCIN 14

15 MUCINOUS ASCITES, PERITONEUM ACELLULAR MUCIN ORGANIZING MUCIN, PERITONEUM CLASSIFICATION OF PMP PMP WITH LOW GRADE HISTOLOGIC FEATURES: LOW GRADE MUC CA PERITONEI OR DISSEMINATED PERITONEAL ADENOMUCINOSIS 15

16 LOW GRADE PERITONEAL MUCINOUS NEOPLASIA HOW PSCELLULAR IS THE PSEUDOMYXOMA? WHO DISSECTING MUCIN WITH FIBROSIS, PERITONEUM 16

17 CLASSIFICATION OF PMP PMP WITH HIGH GRADE HISTOLOGIC FEATURES: HIGH GRADE MUCINOUS CARCINOMA PERITONEI OR PERITONEAL MUCINOUS CARCINOMATOSIS INVASIVE ADENOCARCINOMA APPX AND PERITONEUM PERITONEUM APPX MUCINOUS ADENOCA PERITONEI, HI GRADE CLASSIFICATION OF PMP PMP WITH SIGNET RING CELLS: HIGH GRADE MUC CA PERITONEI WITH SIG RING CELLS OR PERITONEAL MUCINOUS CARCINOMATOSIS WITH SIG RING CELLS 17

18 PERITONEAL COLLOID CARCINOMA: NOT PSEUDOMYXOMA PERITONEI! FINIS 18

Ovarian mucinous lesions. Ovarian mucinous lesions: Common diagnostic dilemmas. Ovarian mucinous lesions: problematic issues

Ovarian mucinous lesions. Ovarian mucinous lesions: Common diagnostic dilemmas. Ovarian mucinous lesions: problematic issues Ovarian mucinous lesions Ovarian mucinous lesions: Common diagnostic dilemmas Karuna Garg, MD University of California San Francisco Intestinal or usual type Seromucinous (Endocervical mucinous or Mullerian

More information

Mucinous Cystadenoma of the Ovary

Mucinous Cystadenoma of the Ovary Case Studies [1] September 24, 2012 By Harpreet Singh, MD [2] A 50-year-old female with a history of progressive abdominal distention and discomfort for six months. A 50-year-old female with a history

More information

Uterus. Common pitfalls in the evaluation of gynecologic frozen sections. Gynecologic intraoperative consults

Uterus. Common pitfalls in the evaluation of gynecologic frozen sections. Gynecologic intraoperative consults Common gynecologic intraoperative consults Common pitfalls in the evaluation of gynecologic frozen sections Karuna Garg, MD University of California San Francisco Uterus - Endometrial carcinoma - Myometrial

More information

Cystic tumours of the pancreas and PanIN. Jean-François Fléjou Service d Anatomie Pathologique Hôpital Saint-Antoine, AP-HP, UPMC - Paris 6, France

Cystic tumours of the pancreas and PanIN. Jean-François Fléjou Service d Anatomie Pathologique Hôpital Saint-Antoine, AP-HP, UPMC - Paris 6, France Cystic tumours of the pancreas and PanIN Jean-François Fléjou Service d Anatomie Pathologique Hôpital Saint-Antoine, AP-HP, UPMC - Paris 6, France Cystic tumours of the pancreas Classically rare : - 5%

More information

Outline. Workup for metastatic breast cancer. Metastatic breast cancer

Outline. Workup for metastatic breast cancer. Metastatic breast cancer Metastatic breast cancer Immunostain Update: Diagnosis of metastatic breast carcinoma, emphasizing distinction from GYN primary 1/3 of breast cancer patients will show metastasis 1 st presentation or 20-30

More information

PRIMARY SEROUS CARCINOMA OF PERITONEUM: A CASE REPORT

PRIMARY SEROUS CARCINOMA OF PERITONEUM: A CASE REPORT PRIMARY SEROUS CARCINOMA OF PERITONEUM: A CASE REPORT Dott. Francesco Pontieri (*) U.O. di Anatomia Patologica P.O. di Rossano (CS) Dott. Gian Franco Zannoni Anatomia Patologica Facoltà di Medicina e Chirurgia

More information

Uterus: Endometrial carcinoma. Uterus: Endometrial carcinoma. Common pitfalls in the evaluation of gynecologic frozen sections

Uterus: Endometrial carcinoma. Uterus: Endometrial carcinoma. Common pitfalls in the evaluation of gynecologic frozen sections Common gynecologic intraoperative consults Common pitfalls in the evaluation of gynecologic frozen sections Karuna Garg, MD University of California San Francisco Uterus - Endometrial carcinoma - Myometrial

More information

Pathology of Ovary and Fallopian Tube Thomas C. Wright, Jr.

Pathology of Ovary and Fallopian Tube Thomas C. Wright, Jr. Pelvic Inflammatory Disease Most common diseases: Inflammation - as part of pelvic inflammatory disease Ectopic pregnancy Endometriosis Primary tumors - quite rare Most common causes of PID Chlamydia trachomatis

More information

Mucinous Ovarian Carcinoma

Mucinous Ovarian Carcinoma Mucinous Ovarian Carcinoma Professor Timothy Perren Leeds Institute of Cancer Medicine & Pathology St James s Institute of Oncology University of Leeds and St James s University Hospital Leeds UK Mucinous

More information

Changes in Breast Cancer Reports After Second Opinion. Dr. Vicente Marco Department of Pathology Hospital Quiron Barcelona. Spain

Changes in Breast Cancer Reports After Second Opinion. Dr. Vicente Marco Department of Pathology Hospital Quiron Barcelona. Spain Changes in Breast Cancer Reports After Second Opinion Dr. Vicente Marco Department of Pathology Hospital Quiron Barcelona. Spain Second Opinion in Breast Pathology Usually requested when a patient is referred

More information

Effusions: Mesothelioma and Metastatic Cancers

Effusions: Mesothelioma and Metastatic Cancers Effusions: Mesothelioma and Metastatic Cancers Malignant Mesothelioma Incidence: 2,500 cases/year ~60-80% pts with pleural MM relationship with asbestos exposure Other risk factors: radiation, other carcinogens,

More information

TUMORS OF THE TESTICULAR ADNEXA and SPERMATIC CORD

TUMORS OF THE TESTICULAR ADNEXA and SPERMATIC CORD TUMORS OF THE TESTICULAR ADNEXA and SPERMATIC CORD Victor E. Reuter, MD Memorial Sloan-Kettering Cancer Center reuterv@mskcc.org 66 th Annual Pathology Seminar California Society of Pathologists Short

More information

New Classifications of Appendiceal Tumors and Understanding The Connection Between Appendix and Ovary: The Pathologist's View

New Classifications of Appendiceal Tumors and Understanding The Connection Between Appendix and Ovary: The Pathologist's View New Classifications of Appendiceal Tumors and Understanding The Connection Between Appendix and Ovary: The Pathologist's View Christopher Otis, MD Director, Surgical Pathology Baystate Medical Center Springfield,

More information

IOTA Terminology, Simple Descriptors and Simple Rules

IOTA Terminology, Simple Descriptors and Simple Rules IOTA Terminology, Simple Descriptors and Simple Rules Susanne Johnson Princess Anne Hospital Southampton UK susanne.johnson@uhs.nhs.uk Ovarian pathology ClassificaGon system for ovarian pathology StandardisaGon

More information

Ovarian tumors Ancillary methods

Ovarian tumors Ancillary methods Ovarian tumors Ancillary methods Ovarian tumor course Oslo, 24-25/11/14 Prof. Ben Davidson, MD PhD Department of Pathology, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway Division of

More information

Protocol for the Examination of Specimens From Patients With Tumors of the Peritoneum

Protocol for the Examination of Specimens From Patients With Tumors of the Peritoneum Protocol for the Examination of Specimens From Patients With Tumors of the Peritoneum Protocol applies to all primary borderline and malignant epithelial tumors and malignant mesothelial neoplasms of the

More information

ADENOCARCINOMA OF THE ENDOCERVIX. July Elvio G. Silva. Baylor Health Care System Dallas, TX. Cedars-Sinai Medical Center Los Angeles, CA

ADENOCARCINOMA OF THE ENDOCERVIX. July Elvio G. Silva. Baylor Health Care System Dallas, TX. Cedars-Sinai Medical Center Los Angeles, CA ADENOCARCINOMA OF THE ENDOCERVIX July 2013 Elvio G. Silva Baylor Health Care System Dallas, TX Cedars-Sinai Medical Center Los Angeles, CA The University of Texas MD Anderson Cancer Center Houston, TX

More information

Today s Topics. Tumors of the Peritoneum in Women

Today s Topics. Tumors of the Peritoneum in Women Today s Topics Tumors of the Peritoneum in Women Charles Zaloudek, M.D. Department of Pathology 505 Parnassus Ave., M563 University of California, San Francisco San Francisco, CA USA charles.zaloudek@ucsf.edu

More information

Endometrioid Carcinoma of the Ovary and Uterus Synchronous Primaries or Metastasis: A Case Report

Endometrioid Carcinoma of the Ovary and Uterus Synchronous Primaries or Metastasis: A Case Report Pathology Section Case Report Endometrioid Carcinoma of the Ovary and Uterus Synchronous Primaries or Metastasis: A Case Report Eswari V., Geetha Prakash, Irfan A. Ansari, Bhanumathy V., Gomathi Palvannanathan

More information

The Rants and Tirades of a Maniacal Senior Surgery Resident. Sushanth Reddy, M.D. General Surgery Resident University of Kentucky

The Rants and Tirades of a Maniacal Senior Surgery Resident. Sushanth Reddy, M.D. General Surgery Resident University of Kentucky The Rants and Tirades of a Maniacal Senior Surgery Resident Sushanth Reddy, M.D. General Surgery Resident University of Kentucky Last year. XPA 1 120 XPA 3 120 XPA 4 120 90 90 90 60 60 60 30 30 30 10-3

More information

Intraoperative Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Volodymyr Labinskyy MD

Intraoperative Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Volodymyr Labinskyy MD Intraoperative Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Volodymyr Labinskyy MD KCHC 8/29/13 52 y.o. F presented with severe pain in the right back and right flank, sharp, 8 out of 10, for 7 days.

More information

Practical Issues in Endometrial Pathology

Practical Issues in Endometrial Pathology Practical Issues in Endometrial Pathology Elvio G Silva, MD Professor of Pathology The University of Texas M.D. Anderson Cancer Center, Houston, Texas Cedars-Sinai Medical Center, Los Angeles, California

More information

Luis D. Carcorze Soto, MD PGY-3

Luis D. Carcorze Soto, MD PGY-3 Luis D. Carcorze Soto, MD PGY-3 Peritoneal Surface Malignancies Peritoneum Patient Selection Operative Technique HIPEC EPIC Primary: Primary Peritoneal Carcinoma Malignant Peritoneal Mesothelioma Metastatic:

More information

Corporate Medical Policy

Corporate Medical Policy Corporate Medical Policy Hyperthermic Intraperitoneal Chemotherapy File Name: Origination: Last CAP Review: Next CAP Review: Last Review: hyperthermic_intraperitoneal_chemotherapy 5/19/2005 3/2016 3/2017

More information

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Now and the Future

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Now and the Future Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Now and the Future Mazin Al-kasspooles, MD Associate Professor of Surgery Division of Surgical Oncology Director, Regional Therapy

More information

From ICD-9-CM to ICD-10-CM. Coding for Neoplasms

From ICD-9-CM to ICD-10-CM. Coding for Neoplasms From ICD-9-CM to ICD-10-CM Presented by: Kay Kostal, M.Ed., RHIT, CCS Deborah A. Balentine, M.Ed., RHIA, CCS-P North American Association of Central Cancer Registries July 12, 2012 1 Case Studies Case

More information

Liver Imaging. Liver Imaging/Cirrhosis. Signs of Liver Failure and Portal Hypertension. Methods of Imaging the Liver. CT Workhorse of Imaging

Liver Imaging. Liver Imaging/Cirrhosis. Signs of Liver Failure and Portal Hypertension. Methods of Imaging the Liver. CT Workhorse of Imaging Liver Imaging Patricia Lipford Abbitt,, MD Professor and Chief - Body Imaging Section Department of Radiology College of Medicine University of Florida Liver Imaging/Cirrhosis Number of patients with hepatitis

More information

Malignant Adenomyoepithelioma of the Breast with Lymph Node Metastasis

Malignant Adenomyoepithelioma of the Breast with Lymph Node Metastasis Malignant Adenomyoepithelioma of the Breast with Lymph Node Metastasis Ahlam A. Awamleh * Mihir Gudi, Sami Shousha ^ * King Hussein Medical Center, Amman Jordan ^ Charing Cross Hospital, London, UK Introduction

More information

Pseudomyxoma Peritonei Where are we in 2014?

Pseudomyxoma Peritonei Where are we in 2014? Pseudomyxoma Peritonei Where are we in 2014? Santiago González-Moreno, MD, PhD Head, Department of GI Surgical Oncology Peritoneal Surface Oncology Program Medical Director * * * * * * * * * * * * French

More information

Case of the. Month October, 2012

Case of the. Month October, 2012 Case of the Month October, 2012 Case The patient is a 47-year-old male with a 3-week history of abdominal pain. A CT scan of the abdomen revealed a suggestion of wall thickening at the tip of the appendix

More information

Peritoneal Surface Malignancies. Ira Allen Jacobs, MD, FACS Surgical Oncology San Diego, CA

Peritoneal Surface Malignancies. Ira Allen Jacobs, MD, FACS Surgical Oncology San Diego, CA Peritoneal Surface Malignancies Ira Allen Jacobs, MD, FACS Surgical Oncology San Diego, CA Cancer dissemination routes Hematogenous metastases Lymphatic metastases Implants on peritoneal surfaces Surgically

More information

Something Old, Something New.

Something Old, Something New. Something Old, Something New. Michelle A. Fajardo, D.O. Loma Linda University Medical Center Clinical Presentation 6 year old boy, presented with hematuria Renal mass demonstrated by ultrasound & CT scan

More information

Surgical Staging of Endometrial Cancer

Surgical Staging of Endometrial Cancer Surgical Staging of Endometrial Cancer I. Endometrial Cancer Surgical Staging Overview Uterine cancer types: carcinomas type I and type II, sarcomas, carcinosarcomas Hysterectomy with BSO Surgical Staging

More information

Gynecology Abnormal Physiology of the ovaries. Simple Cystic Masses

Gynecology Abnormal Physiology of the ovaries. Simple Cystic Masses Gynecology Abnormal Physiology of the ovaries (Effective February 2007) pediatric, reproductive, and perimenopausal/postmenopausal (24-28 %) Simple Cystic Masses ovary s function is to mature oocytes until

More information

Vol. 30, pp.11 17, 2002 AFIP 2 4 IPMT IPMT. Mucinous Cystic Tumor: MCT. Intraductal Papillary Mucinous Tumor: IPMT

Vol. 30, pp.11 17, 2002 AFIP 2 4 IPMT IPMT. Mucinous Cystic Tumor: MCT. Intraductal Papillary Mucinous Tumor: IPMT Vol. 30, pp.11 17, 2002 14 2 20 9 1 5 20% 1 4 1 10 AFIP 2 4 3 IPMT IPMT IPMT 1982 4 1993 3 Mucinous Cystic Tumor: MCT 1996 WHO 4 1997 AFIP 2 Intraductal Papillary Mucinous Tumor: IPMT 1994 1997 5 6 2 4%

More information

Primary Mucinous Ovarian Cancer (PMOC) Michael Frumovitz December 2, 2011

Primary Mucinous Ovarian Cancer (PMOC) Michael Frumovitz December 2, 2011 Primary Mucinous Ovarian Cancer (PMOC) Michael Frumovitz December 2, 2011 Stage III/IV Mucinous vs. Epithelial Ovarian Cancers Hess et al., 2004 Stage III/IV Mucinous vs. Epithelial Ovarian Cancers Hess

More information

PATHOLOGY OF THE PLEURA: Mesothelioma and mimickers Necessity of Immunohistochemistry. M. Praet

PATHOLOGY OF THE PLEURA: Mesothelioma and mimickers Necessity of Immunohistochemistry. M. Praet PATHOLOGY OF THE PLEURA: Mesothelioma and mimickers Necessity of Immunohistochemistry M. Praet Pathology of the Pleura Normal serosa: visceral and parietal layers Inflammation Neoplasia: Primary: mesothelioma

More information

OCCULT PRIMARY CANCER

OCCULT PRIMARY CANCER OCCULT PRIMARY CANCER พญ.ครองกมล ส หบ ณฑ หน วยมะเร งว ทยา INTRODUCTION Occult primary cancers or cancer of unknown primary (CUPS) Histologically proven metastatic malignant tumors whose primary site cannot

More information

Controversies in the Pathology of the Endometrium. Professor Mike Wells. University of Sheffield. Amman, Jordan November 2013

Controversies in the Pathology of the Endometrium. Professor Mike Wells. University of Sheffield. Amman, Jordan November 2013 Controversies in the Pathology of the Endometrium Professor Mike Wells University of Sheffield Amman, Jordan November 2013 ENDOMETRIAL CANCER increasing in incidence: epidemic of obesity increasing elderly

More information

Common Cancers & Hereditary Syndromes

Common Cancers & Hereditary Syndromes Common Cancers & Hereditary Syndromes Elizabeth Hoodfar, MS, LCGC Regional Cancer Genetics Coordinator Kaiser Permanente Northern California Detect clinical characteristics of hereditary cancer syndromes.

More information

Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei

Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei & 2015 USCAP, Inc. All rights reserved 0893-3952/15 $32.00 S67 Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei Joseph Misdraji Department of Pathology, Massachusetts General Hospital,

More information

Practical Effusion Cytology

Practical Effusion Cytology Practical Effusion Cytology A Community Pathologist s Approach to Immunocytochemistry in Body Fluid Cytology Emily E. Volk, MD William Beaumont Hospital Troy, MI College of American Pathologists 2004.

More information

POSTMENOPAUSAL ASSESS AND WHAT TO DO

POSTMENOPAUSAL ASSESS AND WHAT TO DO POSTMENOPAUSAL OVARIAN CYSTS:HOW TO ASSESS AND WHAT TO DO Steven R. Goldstein, MD Professor of Obstetrics and Gynecology Director of Gynecologic Ultrasound Co-Director, Bone Densitometry New York University

More information

The develpemental origin of mesothelium

The develpemental origin of mesothelium Mesothelioma Tallinn 14.12.06 Henrik Wolff Finnish Institute of Occupational Health The develpemental origin of mesothelium Mesodermal cavities (pleura, peritoneum and pericardium ) are lined with mesenchymal

More information

Ovarian Cancer: 2015 Update Srini Prasad MD The University of Texas MD Anderson Cancer Center

Ovarian Cancer: 2015 Update Srini Prasad MD The University of Texas MD Anderson Cancer Center Ovarian Cancer: 2015 Update Srini Prasad MD The University of Texas MD Anderson Cancer Center No financial disclosures Goals of this Presentation.. Discuss recent advances in pathogenesis of ovarian epithelial

More information

Immunohistochemical differentiation of metastatic tumours

Immunohistochemical differentiation of metastatic tumours Immunohistochemical differentiation of metastatic tumours Dr Abi Wheal ST1. TERA 3/2/14 Key points from a review article written by Daisuke Nonaka Intro Metastatic disease is the initial presentation in

More information

Renal Cell Carcinoma: Advances in Diagnosis B. Iványi, MD

Renal Cell Carcinoma: Advances in Diagnosis B. Iványi, MD Renal Cell Carcinoma: Advances in Diagnosis B. Iványi, MD Department of Pathology University of Szeged, Hungary ISUP Vancouver Classification of Renal Neoplasia Am J Surg Pathol 37:14691489, 2013 13 histologic

More information

Update on Mesothelioma

Update on Mesothelioma November 8, 2012 Update on Mesothelioma Intro incidence and nomenclature Update on Classification Diagnostic specimens Morphologic features Epithelioid Histology Biphasic Histology Immunohistochemical

More information

Two Women with Ovarian Cancer: Mystery Metastasis vs. Primary Tumor

Two Women with Ovarian Cancer: Mystery Metastasis vs. Primary Tumor July 2006 Two Women with Ovarian Cancer: Mystery Metastasis vs. Primary Tumor Jennifer Erdrich,, HMS III Gillian Lieberman, MD Ovarian Cancer 5 th most common cause of female cancer death 5 year survival

More information

FIGO Proposal for Staging Cancer of the Ovary, Fallopian Tube and Peritoneum

FIGO Proposal for Staging Cancer of the Ovary, Fallopian Tube and Peritoneum FIGO Proposal for Staging Cancer of the Ovary, Fallopian Tube and Peritoneum FIGO Gynecology Oncology Committee Rome, October 2012 International Union Against Cancer (UICC) TNM Annual Meeting, May 2013

More information

Cytoreduction and Intraperitoneal Chemotherapy for the Management of Non-Gynecological Peritoneal Surface

Cytoreduction and Intraperitoneal Chemotherapy for the Management of Non-Gynecological Peritoneal Surface J. Exp. Clin. Cancer Res., 22, 4, 2003 - Supplement Cytoreduction and Intraperitoneal Chemotherapy for the Management of Non-Gynecological Peritoneal Surface Malignancy Yan T.D., Esquivel J., Carmignani

More information

PATHOLOGY OF THE OVARY AND CLINICAL CORRELATES

PATHOLOGY OF THE OVARY AND CLINICAL CORRELATES PATHOLOGY OF THE OVARY AND CLINICAL CORRELATES Teri A. Longacre, MD Dept. of Pathology Paula J Adams Hillard, MD Dept. of Obstetrics and Gynecology HHD Autumn 2015 At the conclusion of this session, students

More information

Ovarian masses - CT imaging

Ovarian masses - CT imaging Dr. Sujata Patnaik Review Article Ovarian masses - CT imaging Sujatha Patnaik 1 1 Department of Radiology, Nizam s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India *Corresponding author:

More information

MR Imaging of Peritoneal Malignancy Russell N. Low, MD

MR Imaging of Peritoneal Malignancy Russell N. Low, MD MR Imaging of Peritoneal Malignancy Russell N. Low, MD From: Sharp and Children's MRI Center and Sharp HealthCare, 7901 Frost Street, San Diego, California, 92123. Phone: (858) 939-3600. Email: rlow@ucsd.edu

More information

Abstract. Harrison ML, Jameson C, Gore ME. Mucinous ovarian cancer. Int J Gynecol Cancer 2008;18:209 214. Pathology REVIEW PAPER

Abstract. Harrison ML, Jameson C, Gore ME. Mucinous ovarian cancer. Int J Gynecol Cancer 2008;18:209 214. Pathology REVIEW PAPER Int J Gynecol Cancer 2008, 18, 209 214 REVIEW PAPER Mucinous ovarian cancer M.L. HARRISON*, C. JAMESONy & M.E. GORE* Departments of *Medicine and yhistopathology, Royal Marsden Hospital, London, United

More information

PROGNOSTIC FACTORS IN ADVANSED OVARIAN CANCER

PROGNOSTIC FACTORS IN ADVANSED OVARIAN CANCER PROGNOSTIC FACTORS IN ADVANSED OVARIAN CANCER Dr. Hisham Rahahle Gynecologist, MD, Ph.D Subspecialty in Gynecological Oncology E-mail: hisham_re@yahoo.com Abstract: This study includes (68) patient diagnosed

More information

The Adnexal Mass and Early Ovarian Cancer

The Adnexal Mass and Early Ovarian Cancer The Adnexal Mass and Early Ovarian Cancer Fred Ueland, MD University of Kentucky Gynecologic Oncology Never give in. Never give in. Never, never, never, never- in nothing great or small, large or petty-

More information

Immunostain Update: Diagnosis of Metastatic Breast Carcinoma, Emphasizing the Distinction from Gynecologic Cancers

Immunostain Update: Diagnosis of Metastatic Breast Carcinoma, Emphasizing the Distinction from Gynecologic Cancers Immunostain Update: Diagnosis of Metastatic Breast Carcinoma, Emphasizing the Distinction from Gynecologic Cancers Yunn-Yi Chen, M.D., Ph.D. UCSF Pathology Department yunn-yi.chen@ucsf.edu June 3, 2010

More information

Ovarian Cancer. Stacey N. Akers, MD July 14, 2015

Ovarian Cancer. Stacey N. Akers, MD July 14, 2015 Ovarian Cancer Stacey N. Akers, MD July 14, 2015 Ovarian cancer Statistics Risk factors Inherited Syndromes Prevention Diagnosis Staging Treatment Overview Ovarian Cancer Epidemiology 9 th most common

More information

PATOLOGIA MOLECULAR DEL CANCER GINECOLOGICO. Xavier Matias-Guiu Hospital Universitari Arnau de Vilanova, Universitat de Lleida, IRBLLEIDA.

PATOLOGIA MOLECULAR DEL CANCER GINECOLOGICO. Xavier Matias-Guiu Hospital Universitari Arnau de Vilanova, Universitat de Lleida, IRBLLEIDA. PATOLOGIA MOLECULAR DEL CANCER GINECOLOGICO Xavier Matias-Guiu Hospital Universitari Arnau de Vilanova, Universitat de Lleida, IRBLLEIDA. Carcinoma de Endometrio Cáncer de Ovario Endometrial carcinoma

More information

MALIGNANT MESOTHELIOMA UPDATE ON PATHOLOGY AND IMMUNOHISTOCHEMISTRY

MALIGNANT MESOTHELIOMA UPDATE ON PATHOLOGY AND IMMUNOHISTOCHEMISTRY MALIGNANT MESOTHELIOMA UPDATE ON PATHOLOGY AND IMMUNOHISTOCHEMISTRY Sisko Anttila, MD, PhD Jorvi Hospital Laboratory of Pathology Helsinki University Hospital Espoo, Finland 2nd Nordic Conference on Applied

More information

Protocol applies to all primary borderline and malignant epithelial tumors, and malignant mesothelial neoplasms of the peritoneum.

Protocol applies to all primary borderline and malignant epithelial tumors, and malignant mesothelial neoplasms of the peritoneum. Peritoneum Protocol applies to all primary borderline and malignant epithelial tumors, and malignant mesothelial neoplasms of the peritoneum. Protocol revision date: January 2004 No AJCC/UICC staging system

More information

H. Richard Alexander, Jr., M.D. Department of Surgery and The Greenebaum Cancer Center University of Maryland School of Medicine Baltimore, Md

H. Richard Alexander, Jr., M.D. Department of Surgery and The Greenebaum Cancer Center University of Maryland School of Medicine Baltimore, Md Major Advances in Cancer Prevention, Diagnosis and Treatment~ Why Mesothelioma Leads the Way H. Richard Alexander, Jr., M.D. Department of Surgery and The Greenebaum Cancer Center University of Maryland

More information

- Slide Seminar - Endocrine pathology in non-endocrine organs. Case 11. Stefano La Rosa, Gioacchino D Ambrosio, Fausto Sessa

- Slide Seminar - Endocrine pathology in non-endocrine organs. Case 11. Stefano La Rosa, Gioacchino D Ambrosio, Fausto Sessa - Slide Seminar - Endocrine pathology in non-endocrine organs Case 11 Stefano La Rosa, Gioacchino D Ambrosio, Fausto Sessa Dept. of Pathology, Multimedica, Milan, Italy Dept. of Surgical and Morphological

More information

Pathology of the Endometrium. Thomas C. Wright Columbia University, New York, NY. Most common diseases:

Pathology of the Endometrium. Thomas C. Wright Columbia University, New York, NY. Most common diseases: Pathology of the Endometrium Thomas C. Wright Columbia University, New York, NY Endometrium Most common diseases: Abnormal uterine bleeding Inflammatory conditions Benign neoplasms Endometrial cancer Page

More information

IMMUNOHISTOCHEMISTRY

IMMUNOHISTOCHEMISTRY IMMUNOHISTOCHEMISTRY lot of immunophenotypic overlap between cervical MGH and changes on surface of endometrioid adenocarcinoma? vimentin and p16 may be of value IN PRACTICE- IMMUNOHISTOCHEMISTRY OF LIMITED

More information

MALIGNANT MESOTHELIOMA UPDATE ON PATHOLOGY AND IMMUNOHISTOCHEMISTRY

MALIGNANT MESOTHELIOMA UPDATE ON PATHOLOGY AND IMMUNOHISTOCHEMISTRY MALIGNANT MESOTHELIOMA CLASSIFICATION MALIGNANT MESOTHELIOMA UPDATE ON PATHOLOGY AND IMMUNOHISTOCHEMISTRY Sisko Anttila, MD, PhD Jorvi Hospital Laboratory of Pathology Helsinki University Hospital Espoo,

More information

Cystic Neoplasms of the Pancreas: A multidisciplinary approach to the prevention and early detection of invasive pancreatic cancer.

Cystic Neoplasms of the Pancreas: A multidisciplinary approach to the prevention and early detection of invasive pancreatic cancer. This lecture is drawn from the continuing medical education program Finding Hope: Prevention, Early Detection and Treatment of Pancreatic Cancer, Nov, 2011. Robert P. Jury, MD Cystic Neoplasms of the Pancreas:

More information

Ovarian cysts Diagnosis and Management

Ovarian cysts Diagnosis and Management Ovarian cysts Diagnosis and Management Mr P K Athanasias MRCOG Consultant Gynaecologist St Anthony s Hospital pathanasias@gmail.com Introduction ovary is an ovum-producing reproductive organ located in

More information

NEOPLASMS C00 D49. Presented by Jan Halloran CCS

NEOPLASMS C00 D49. Presented by Jan Halloran CCS NEOPLASMS C00 D49 Presented by Jan Halloran CCS 1 INTRODUCTION A neoplasm is a new or abnormal growth. In the ICD-10-CM classification system, neoplastic disease is classified in categories C00 through

More information

ProSono Copyright 2006. Ovarian Pathology

ProSono Copyright 2006. Ovarian Pathology Ovarian Pathology Physiologic cysts: Functional cysts Pathology: A simple cyst is a sac containing fluid or semi-solid material. Physiologic cysts are generic types of hormonally active cysts that result

More information

Common Challenges in Endometrial Biopsy Interpretation. Aaron Haig

Common Challenges in Endometrial Biopsy Interpretation. Aaron Haig Common Challenges in Endometrial Biopsy Interpretation Aaron Haig Conflict of Interest Disclosures Aaron Haig I have not had in the past 3 years, a financial interest, arrangement or affiliation with one

More information

MALIGNANT MESOTHELIOMA: A TYPICAL PRESENTATION IN AN ATYPICAL PATIENT

MALIGNANT MESOTHELIOMA: A TYPICAL PRESENTATION IN AN ATYPICAL PATIENT MALIGNANT MESOTHELIOMA: A TYPICAL PRESENTATION IN AN ATYPICAL PATIENT Written by: Karyn Varley MS, SCT(ASCP) The donating laboratory would like to remain anonymous. PATIENT HISTORY 28 year old female Lived

More information

ENDOMETRIAL CANCER. Dr P Mukonoweshuro Consultant Pathologist RUH Bath

ENDOMETRIAL CANCER. Dr P Mukonoweshuro Consultant Pathologist RUH Bath ENDOMETRIAL CANCER Dr P Mukonoweshuro Consultant Pathologist RUH Bath Endometrial tumours Epithelial Mesenchymal Mixed epithelial and mesenchymal Trophoblastic Lymphoid Miscellaneous tumours e.g. sex cord

More information

National Coverage Determination (NCD) for Tumor Antigen by Immunoassay - CA 125 (190.28)

National Coverage Determination (NCD) for Tumor Antigen by Immunoassay - CA 125 (190.28) National Coverage Determination (NCD) for Tumor Antigen by Immunoassay - CA 125 (190.28) Tracking Information Publication Number Manual Section Number 100-3 190.28 Manual Section Title Tumor Antigen by

More information

Renal Pathology Update. Sundus Hussein MD, FRCPC

Renal Pathology Update. Sundus Hussein MD, FRCPC Renal Pathology Update Sundus Hussein MD, FRCPC Case History A 45 year old male with incidentally discovered a 3.5 x 3.9 x 2.7 cm renal mass Handling partial nephrectomy Handling partial nephrectomy

More information

Harvard-MIT Division of Health Sciences and Technology HST.071: Human Reproductive Biology Course Director: Professor Henry Klapholz

Harvard-MIT Division of Health Sciences and Technology HST.071: Human Reproductive Biology Course Director: Professor Henry Klapholz Harvard-MIT Division of Health Sciences and Technology HST.071: Human Reproductive Biology Course Director: Professor Henry Klapholz IN SUMMARY HST 071 OVARIAN PATHOLOGY Types of Ovarian Tumors Epithelial

More information

Ovarian Cancer- Radiographic Diagnosis and Staging

Ovarian Cancer- Radiographic Diagnosis and Staging July 2002 Ovarian Cancer- Radiographic Diagnosis and Staging Ileana Howard, Harvard Medical School Year III Patient #1: Ms. S 51 y.o.. female, G0P0 Presented to E.D. with abdominal distension Liver enzymes

More information

Carcinosarcoma of the Ovary

Carcinosarcoma of the Ovary Carcinosarcoma of the Ovary A Rare Finding Presented By: Kathryn Kiely Anisa I. Kanbour School of Cytotechnology of the University of Pittsburgh Medical Center Pittsburgh, PA Patient History 55 year old

More information

Endometrial carcinoma: practical part. Gerd JACOMEN AZ St Maarten Duffel/Mechelen

Endometrial carcinoma: practical part. Gerd JACOMEN AZ St Maarten Duffel/Mechelen Endometrial carcinoma: practical part Gerd JACOMEN AZ St Maarten Duffel/Mechelen Case 1: presentation Age: 68 y Symptoms: postmenopausal bleeding US: Endometrial thickness 20mm Novak-biopsy: inconclusive

More information

Brigitte M. Ronnett, M.D. Department of Pathology The Johns Hopkins University School of Medicine Baltimore, MD. Disclosures

Brigitte M. Ronnett, M.D. Department of Pathology The Johns Hopkins University School of Medicine Baltimore, MD. Disclosures Uterine Adenocarcinomas: Ancillary Techniques in the Distinction of Endometrial and Endocervical Adenocarcinomas and Subtyping of Endometrial Adenocarcinomas Brigitte M. Ronnett, M.D. Department of Pathology

More information

Cancer of the Exocrine Pancreas, Ampulla of Vater and Distal Common Bile Duct Proforma

Cancer of the Exocrine Pancreas, Ampulla of Vater and Distal Common Bile Duct Proforma Cancer of the Exocrine, Ampulla of Vater and Distal Coon Bile Duct Proforma Mandatory questions (i.e. protocol standards) are in bold (e.g. S1.03). Family name Given name(s) Sex Male Female Intersex/indeterminate

More information

National Medical Policy

National Medical Policy National Medical Policy Subject: Policy Number: Intraperitoneal Hyperthermic Chemotherapy for Abdominopelvic Cancers NMP346 Effective Date*: June 2007 Updated: November 2014 This National Medical Policy

More information

Case Number: RT2009-124(M) Potential Audiences: Intent Doctor, Oncology Special Nurse, Resident Doctor

Case Number: RT2009-124(M) Potential Audiences: Intent Doctor, Oncology Special Nurse, Resident Doctor Renal Cell Carcinoma of the Left Kidney Post Radical Surgery with pt4 Classification with Multiple Lung and Single Brain Metastases: the Role and Treatment Consideration of Radiotherapy Case Number: RT2009-124(M)

More information

Endometrial Cancer Treatment

Endometrial Cancer Treatment Endometrial Cancer Treatment January 2006 By Shelly Smits, RHIT, CCS, CTR mary by Ian Thompson, MD Data Source: Cancer registry information on uterine cancer diagnosed 1/1/2000 to 12/31/2004. Reason for

More information

I would like to discuss risk factors and multi-steps involved in breast carcinogenesis and mechanisms of invasion and metastasis of breast cancer.

I would like to discuss risk factors and multi-steps involved in breast carcinogenesis and mechanisms of invasion and metastasis of breast cancer. Hello. My name is Ayse Sahin. I m a Professor of Pathology at University of Texas MD Anderson Cancer Center. I would like to review Pathology of Breast Cancer. Upon completion of this lecture, participants

More information

Introduction to Premalignant Endometrial Disease

Introduction to Premalignant Endometrial Disease Page 1 Slide 1 Introduction A mini lecture from www.endometrium endometrium.org Introduction to Premalignant Endometrial Disease This is Dr. George Mutter, I am a gynecologic pathologist at Harvard Medical

More information

Epithelial Ovarian Cancer

Epithelial Ovarian Cancer Epithelial Ovarian Cancer Fred Ueland, MD University of Kentucky Gynecologic Oncology Risk Factors Incessant ovulation Early menarche, late menopause, low parity Family history Acquired genetic mutations

More information

ACG Regional Postgraduate Course June 6-8, Washington, DC. Pancreatic Cysts What is Benign versus Not-so-benign

ACG Regional Postgraduate Course June 6-8, Washington, DC. Pancreatic Cysts What is Benign versus Not-so-benign ACG Regional Postgraduate Course June 6-8, 2014. Washington, DC Pancreatic Cysts What is Benign versus Not-so-benign Asif Khalid MD Associate Professor of Medicine University of Pittsburgh Medical Center

More information

Multiple Primary and Histology Site Specific Coding Rules KIDNEY. FLORIDA CANCER DATA SYSTEM MPH Kidney Site Specific Coding Rules

Multiple Primary and Histology Site Specific Coding Rules KIDNEY. FLORIDA CANCER DATA SYSTEM MPH Kidney Site Specific Coding Rules Multiple Primary and Histology Site Specific Coding Rules KIDNEY 1 Prerequisites 2 Completion of Multiple Primary and Histology General Coding Rules 3 There are many ways to view the Multiple l Primary/Histology

More information

Radiologic Diagnosis and Staging of Ovarian Cancer

Radiologic Diagnosis and Staging of Ovarian Cancer January 2006 Radiologic Diagnosis and Staging of Ovarian Cancer Christina Coleman Harvard Medical School Year III Outline Typical Patient Presentation Epidemiology of Ovarian Cancer Menu of Test Available

More information

Case Number: RT2009 124-2(M) Potential Audiences: Intent Doctor, Oncology Special Nurse, Resident Doctor

Case Number: RT2009 124-2(M) Potential Audiences: Intent Doctor, Oncology Special Nurse, Resident Doctor Renal Cell Carcinoma of the Left Kidney Post Radical Surgery with pt4 Classification with Multiple Lung and Single Brain Metastases Post Chemotherapy and Brain RT with Local-Regional Recurrence with Bilateral

More information

BIOBANK LPCE-NICE CHEST

BIOBANK LPCE-NICE CHEST BIOBANK LE-NIE HEST athologist : S. LASSALLE 01/03/2011 Time for frozen procedure : 10 mn LE / HU Unit atient : N LH 11-0004 N LB 11-0002 onsent : YES Age : 37 ID : TH ER Diagnosis and staging : Hodgkin

More information

Pancreatic Cancer. The Killer that must be discovered early. Dr Alfred Kow Wei Chieh

Pancreatic Cancer. The Killer that must be discovered early. Dr Alfred Kow Wei Chieh Pancreatic Cancer The Killer that must be discovered early 27 th June 2015 Dr Alfred Kow Wei Chieh Consultant Department of Surgery Division of HPB Surgery & Liver Transplantation & Assistant Dean (Education)

More information

Paranasal sinus anatomy

Paranasal sinus anatomy Paranasal sinus anatomy Sphenoid Nasopharynx Respiratory mucosa Pseudostratified, goblet & ciliated cells Seromucinous glands Nasopharyngeal mucosa/carcinoma Squamous metaplasia (?) with CIS Normal respiratory

More information

DISCLOSURE OBJECTIVES IN THE INEREST OF TIME LAPAROSCOPY AND AN APPROACH TO THE ADNEXAL MASS

DISCLOSURE OBJECTIVES IN THE INEREST OF TIME LAPAROSCOPY AND AN APPROACH TO THE ADNEXAL MASS LAPAROSCOPY AND AN APPROACH TO THE ADNEXAL MASS DISCLOSURE I do not have any financial relationship with commercial interests. Michael Traynor Michael Traynor MD MPH Northwest Permanente, PC KAISER PERMANENTE

More information

Uterine Fibroids: Not As Simple As You Think.

Uterine Fibroids: Not As Simple As You Think. Uterine Fibroids: Not As Simple As You Think jeffrey.weinreb@yale.edu Uterine Leiomyoma Most common uterine neoplasm 20-30% women >35yo Under hormonal influence Enlarge during pregnancy or BCP use Regress

More information

Ovarian Cancer: A Case Report

Ovarian Cancer: A Case Report Ovarian Cancer: A Case Report Abstract Ovarian cancer is a very common cancer among women. It is an extremely diverse disease requiring several treatment options. Occasionally ovarian cancer is diagnosed

More information

Images removed due to copyright reasons.

Images removed due to copyright reasons. Harvard-MIT Division of Health Sciences and Technology HST.071: Human Reproductive Biology Course Director: Professor Henry Klapholz Images removed due to copyright reasons. Here is another common incidental

More information

CLINICAL MANAGEMENT OF INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS OF THE PANCREAS

CLINICAL MANAGEMENT OF INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS OF THE PANCREAS 1 CLINICAL MANAGEMENT OF INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS OF THE PANCREAS Carlos Fernández-del Castillo, M.D. Associate Professor of Surgery Massachusetts General Hospital Harvard Medical School,

More information