Development of Serenade as a biopesticide against plant bacterial diseases
|
|
- Michael Weaver
- 7 years ago
- Views:
Transcription
1 Development of Serenade as a biopesticide against plant bacterial diseases COST 873 Thierry Merckling, Denise Manker, Manuele Ricci, Sarah reiter October 26-27, 2009 Cetara
2 Agenda Introducing AgraQuest Serenade : Mode of action Field Experience in bacterial diseases control Situation in Europe Future developments
3 Headquarters - Davis, California 3 October 27, 2009 CONFIDENTIAL
4 Discovery & Development Highest hurdles for development and in-licensing of products. Efficacy, safety & consistency. 4 October 27, 2009 CONFIDENTIAL
5 R&D Organization Experienced & diverse team of 40 scientists and professionals: Entomology Plant Pathology Fermentation Microbiology Analytical Chemistry Formulation Informatics Regulatory Product Development 5 October 27, 2009 CONFIDENTIAL
6 2009 AgraQuest, Inc. SERENADE, SONATA, RHAPSODY, & BALLAD are registered trademarks of AgraQuest, Inc. These trademarks are registered in the U.S.Patent and Trademark Office as well as in the intellectual property offices of numerous other countries worldwide. The SERENADE and RHAPSODY products are protected by U.S. Patent Nos , , , , and patents in numerous other countries. In addition, these products are protected by The SONATA and BALLAD products are covered by U.S. Patent Nos , , and and by patents in numerous other countries. BARITONE is a trademark of AgraQuest, Inc. The BARITONE product is manufactured and distributed subject to EPA Reg. No BARITONE Bio-Insecticide is currently registered for use in the following states: Arizona, California, Colorado, Florida, Georgia, Idaho, Maryland, Michigan, Nevada, North Carolina, Oregon, South Carolina, Virginia and Washington Products comprising the Muscodor fungus are protected by U.S. Patent No. 6,911,338 and are the subject of numerous pending patent applications worldwide. AgraQuest owns the following product registrations: SERENADE MAX - EPA Reg. No ; SERENADE ASO - EPA Reg. No ; SONATA - EPA Reg. No These products are also registered in numerous other countries worldwide. 6
7 What is SERENADE?
8 SERENADE Fungicide and Bactericide SERENADE is a highly effective broad spectrum fungicide and bactericide bundling several modes of action for a wide spectrum of control with little potential for resistance Based on the proprietary active ingredient, Bacillus subtilis QST713; a naturally occurring strain Each bag or jug contains chemical compounds produced by QST713 during fermentation, as well as spores QST713 is unique in its production of both antifungal and antibacterial compounds During production, we control fermentation parameters in order to optimize output of these compounds 8 October 27, 2009 CONFIDENTIAL
9 Disease Control 1. Broad anti-fungal activity 4 Modes of Action Lipopeptides kill fungal cells They are highly stable, resistant to elevated temp and ph extremes Synergistic activity of 3 different classes 2. Anti-bacterial activity 3+ major chemical classes Activity on gram positive/negative pathogens Stable through spray drying Plant Activation 3. Plant Defense mechanisms Elicits plant responses - SAR (Systemic Acquired Resistance) or ISR (Induced Systemic Resistance) 4. Growth Promoting 9 Enhances yield Improves quality
10 1. Anti-fungal activity Only QST 713 produces this unique group of three lipopeptide classes Each peak is a unique compound which contributes to anti-fungal activity RT: Relative Abundance Iturins 8.88 Surfactins NL: 1.07E8 Base Peak F: + c Full ms Agrastatins/ Plipastatins Time (min) 10 CONFIDENTIAL
11 2. Anti-bacterial Activity QST 713 produces at least 3 classes of anti-bacterial compounds The classes have different modes of anti-bacterial action Compounds are not used in human or animal health Block bacterial cell protein production and cell wall formation Efficacy against broad range of bacterial pathogens Clavibacter, Pseudomonas, Xanthomonas, Erwinia Lipopeptides are not involved in anti-bacterial control Macrolactins Difficidins Bacillicine 11
12 3. Plant Activating SERENADE triggers plants internal defenses and physiological responses Activated when SERENADE contacts the plant The effect is systemic responses are triggered throughout the plant even when a small area is treated SERENADE induces resistance to disease Proven with bioassay and RNA analysis Activated pathway is distinct from salicylic acid (SAR, systemic acquired resistance) and jasmonic acid (ISR, induced systemic resistance) pathways 12
13 Plant Health Induced Resistance Measurement of PR gene expression Clear induction of PR-1 by SERENADE on untreated leaves Water Elicitine SERENADE Day after treatment 0 4 Elicitine (positive control) is a known inducer of pathogenesis related proteins such as PR-1 White indicates RNA expression Induction of PR-1 gene expression on tobacco leaves treated by water, Elicitin and SERENADE. RT-PCR were carried out on mrna extracted after 0 and 4 days of incubation from untreated upper leaves (SAR project) of tobacco plants. 13
14 Tomato Xanthomonas perforans **Error bars represent 95% confidence intervals 14
15 4. Plant Growth Promotion SERENADE applied at planting stimulates growth Tomato seeds treated with SERENADE in furrow when planted in sterile soil at different field rates (oz/acre) Treatment was to soil (not as seed treatment) Plants are compared at same days after planting This is not an anti-fungal (soil was disease-free) nor a fertilizer effect 0 oz. 4 oz. 8 oz. 16 oz. SERENADE applied to tomatoes in furrow at seeding, pathogen free (70215) 15 CONFIDENTIAL
16 Spectrum of Activity: Major Global Crops / Diseases CROP Grape Vine, table Tomato, pepper, eggplant Cucumber, Melon, squash, lettuce Strawberry, Soft fruits, Pome fruit Stone fruit Beans, Onions, garlic Potato, asparagus, carots, Ornamentals Roses, Chrysanthemums Citrus Banana Mango DISEASE Botrytis, sour rot, powdery mildew Botrytis, early blight (alternaria) Powdery mildew (leveillula) bacterial leaf spot (xanthomonas) Powdery mildew, Botrytis, downy mildew Leaf drop (sclerotinia) Botrytis, anthracnose Apple scab (venturia), fire blight (erwinia),powdery mildew Monilia, Bacterial spot (xanthomonas) White mold (sclerotinia), Neck rot (Botrytis) Leaf spots (erwinia, xanthomonas, pseudomonas) Bacterial wilt (ralstonia) Canker Black sigatoka Anthracnose, Powdery mildew
17 Bacterial Control Spectrum Crop Disease Common Name Pome Erwinia amylovora Fire blight Tomato / Pepper Blueberry Peaches Citrus Xanthomonas campestris pv vesicatoria Pseudomonas syringae Pseudomonas syringae pv syringae Xanthomonas arboricola pv pruni Xanthomonas axonopodis pv citri Bacterial leaf spot Bacterial speck Bacterial blight Bacterial leaf spot Citrus canker Note: Approved uses vary depending on region and regulatory authority 17
18
19 Results of field trials
20 Provides Fire Blight control on Apples, and helps reduce resistance G.W. Sundin, Mich State Univ., East Lansing, MI
21 Controls Fire Blight on Apples AgriAssistance, Wayne Co., NY Erwinia amylovora. (60303) 21
22 Controls Fire Blight on Pears S. Lindow, Univ. of California Extension, CA Erwinia amylovora. (40190) 22
23 Serenade against fire blight TIMING AT FLOWERING: apply Serenade at 10-20% flowering in order to prevent the frequently asymptomatic multiplication of the pathogen on the flower; bees can contribute to the spread of B. subtilis spores among flowers. Application rate: either 1 single application at 2-3 kg/ha or 2-3 successive applications at 1 kg/ha during flowering (also in tank mixture with fungicides). UNDER CONDITIONS FAVOURABLE TO INFECTION (hail, storms, days at high risk of infection due to temperature and humidity conditions, etc.) and at APPEARANCE OF SECONDARY BLOSSOMS (pear) Application rate: 2-3 kg/ha, also in tank mixture with copper-based products, both at a reduced rate (Serenade at 1.5 kg/ha).
24 Bacterial Spot Control on Tomatoes SERENADE MAX spray program NCSU recommended spray program Dr. Kelly Ivors, 2006 NCSU Mountain Hort. Crops REC Untreated Check 24
25 Pseudomonas Syringae (Bacterial Speck) on Tomatoes a ab b b b D. Hicks, Hulst Research Farm, Hughson, CA Pseudomonas syringae. (50110) 25
26 Controls Bacterial Leaf Spot on Tomatoes a 1 SERENADE 1lb + Kocide 2lb (A, C, E) + Biotune (B, D, F) Quadris 6.2oz 2 Tanos 8oz + Manzate 2lb (A, C) + Kocide lb Manzate 2lbs + Kocide 1.5lb Tanos 8oz + Bravo 2pt + Kocide 1.5lb (E) Bravo 2pts + Kocide 1.5lb (F) (A, C, E) 3 Endura 3oz (B, D, F) Bravo 2pt (B, D) c bc bc D. Egel, SW Purdue Agricultural Center Application timing: A = 6/15, B = 6/29, C = 7/06, D = 7/18, E = 7/28, F = 8/03. Xanthomonas campestris (60318) 26
27 Provides excellent control of Blight in High Bush Blueberry when applied 3 times at 2 or 3kg/ha a b b ab ICMS Inc, Canada Three applications timed to bud swell, bud break and visible buds. (80152) 27
28 Provides control of Citrus Canker on Grapefruit a bc ab c Charles Mellinger, Glades Crop Care, Palm Beach Co., FL Nine applications, 14 day intervals, starting March 28. Rating Aug 16. Same letters NSD, 0.1, Student- Newman-Keuls. AgraQuest generated data. Aug. 16 evaluation date. (60402) 28
29 Controls Canker on Peaches c b b Prof. Bazzi, Univ. of Bologna 200 Xanthomonas arboricola pv. Pruni 7. Serenade applied one day before artificial inoculation and one day after inoculation. Severity rated two weeks after second application. (70640) 29
30 Controls Bacterial Canker in Cherries Gary Grove, Washington State Univ., Prosser, WA Pseudomonas syringae. (50118) 30 SERENADE 2lb acre at Fall 90% leaf drop, Spring popcorn and Spring late dormant. SERENADE Program: 1) SERENADE 2lb + NutriPhite 2qt + New Cop 50 at 2.5lb at Fall 90% leaf crop 2) SERENADE 2lb + NutriPhite 2qt at Spring Popcorn 3) SERENADE 2lb + NutriPhite 2qt at Spring late dormant Cuprofix Disperss 20DF 2.5lb at Spring late dormant.
31 SERENADE Registrations: Europe Registration granted SWEDEN Registration submitted FINLAND NORWAY No Registration ESTONIA DENMARK LITHUANIA LATVIA REPULIC OF IRELAND UNITED KINGDOM NETHERLANDS GERMANY POLAND BELARUS BELGIUM CZECH REPUBLIC UKRAINE SLOVAKIA FRANCE SWITZERLAND ITALY AUSTRIA SLOVENIA HUNGARY ROMANIA BULGARIA PORTUGAL SPAIN GREECE TURKEY 31
32 Serenade uses for bacterial diseases control in Europe Tomato Pseudomonas syringae, Xanthomonas Italy, France (*) Pome fruit Erwinia amylovora Italy, France (*), Germany, Switzerland, Stone fruits Xanthomonas arboricola Italy Tree nuts Xanthomonas France Tropical fruits Bacterial diseases France
33 SERENADE: recognized by industry as a resistance management tool Novel, low resistance risk mode of action designated by FRAC (2009 update) Contact agent Major target is cell membrane (not a protein). No simple mutation that can make cell resistant MOA TARGET SITE AND CODE GROUP NAME CHEMICAL GROUP COMMON NAME COMMENTS FRAC CODE F: lipids and membrane synthesis F6: microbial disrupters of pathogen cell membranes B. subtilis Bacillus subtilis and the fungicidal lipopeptides they produce Bacillus subtilis strain QST 713 No resistance reported. Assumed to be low risk based on mode of action of nonspecific membrane disruption CONFIDENTIAL
34 Conclusion Serenade largely used in programs and Integrated Crop management program against bacterial diseases R&D effots to characterize the mode of action Large base of trials and data which support the use of Serenade Strong commitment to continue to develop biopesticides and new solutions for bacterial disease management
35 Thank you 35
Analysis of the EU fruit and vegetables sector
26 September 2014 Analysis of the EU fruit and vegetables sector EU and to Russia (2011-2013) Recent market s and measures taken to address market disruptions following the Russian import ban EU and to
More informationBacterial Diseases of Tomato: 2012
Bacterial Diseases of Tomato: 2012 Bacterial diseases of tomato Bacterial speck Bacterial spot Bacterial canker Bacterial diseases of tomato Bacterial speck- causes lesions on leaves, stems and fruit.
More informationFOLPAN 50 WP (FOLPET) FUNGICIDE COMMERCIAL
21-NOV-2008 2008-4133 GROUP M FUNGICIDE FOLPAN 50 WP (FOLPET) FUNGICIDE COMMERCIAL A wettable powder fungicide for the control of a number of fungus diseases on certain fruit, vegetable, ornamental and
More informationNEW PASSENGER CAR REGISTRATIONS BY ALTERNATIVE FUEL TYPE IN THE EUROPEAN UNION 1 Quarter 4 2015
NEW PASSENGER CAR REGISTRATIONS BY ALTERNATIVE FUEL TYPE IN THE Quarter 4 2015 Alternative fuel vehicle (AFV) registrations: +20.0% in 2015; +21.1% in Q4 In the fourth quarter of 2015, total alternative
More informationGeneral Technical Dossier Laminarin
General Technical Dossier Laminarin The choice to produce better Fruits and vegetables Contents Technical dossier Laminarin 1) Plant natural defense mechanisms. 2) Laminarin: mode of action. 3) Laminarin:
More informationSpray or Dust. Controls disease on potatoes, tomatoes, fruits, flowering shrubs and shade trees WARNING. (Bordeaux Modern Replacement)
(Bordeaux Modern Replacement) Spray or Dust Controls disease on potatoes, tomatoes, fruits, flowering shrubs and shade trees ACTIVE INGREDIENT: Basic Copper Sulfate* (CAS No. 1344-73-6).......................
More informationGfK PURCHASING POWER INTERNATIONAL
GfK PURCHASING POWER INTERNATIONAL 1 Agenda 1. Europe 3 2. Americas 45 3. Asia & Near East 54 4. Afrika 66 5. Australia 68 6. Overview of countries and available levels 70 2 2 EUROPE 4 GfK
More informationKumulus FUNGICIDES. Active ingredient: sulphur...800 g / kg
Reg. No. L2404; N AR 0732 Act No. 36 of 1947 A water dispersible granular fungicide and acaricide for the control of powdery mildew, various other fungal diseases as well as certain mites and thrips on
More information"Fingerprinting" Vegetables DNA-based Marker Assisted Selection
"Fingerprinting" Vegetables DNA-based Marker Assisted Selection Faster, Cheaper, More Reliable; These are some of the goals that vegetable breeders at seed companies and public institutions desire for
More informationBARRIERS TO WIDESPREAD CONVERSION FROM CHEMICAL PEST CONTROL TO NON-CHEMICAL METHODS IN U.S. AGRICULTURE
BARRIERS TO WIDESPREAD CONVERSION FROM CHEMICAL PEST CONTROL TO NON-CHEMICAL METHODS IN U.S. AGRICULTURE 1 Leonard Gianessi and 2 Nathan Reigner CropLife Foundation, Crop Protection Research Institute,
More informationFocus Group IPM for brassica Starting Paper
Tasks of the focus group Stocktaking of the state of the art of practice, including a summary of problems and issues: identify (types of) pests and diseases relevant for Brassica for different EU regions;
More informationEuropean Research Council
ERC Advanced Grants 2011 Outcome: Indicative Statistics Reproduction is authorised provided that the source ERC is acknowledged NB: In these graphs grantee refers to a candidate selected for ERC funding
More informationSize and Development of the Shadow Economy of 31 European and 5 other OECD Countries from 2003 to 2015: Different Developments
January 20, 2015 ShadEcEurope31_January2015.doc Size and Development of the Shadow Economy of 31 European and 5 other OECD Countries from 2003 to 2015: Different Developments by Friedrich Schneider *)
More informationLiquid Copper Fungicide. Superior Quality, Convenience and Performance
Liquid Copper Fungicide Superior Quality, Convenience and Performance Tri-Base Blue liquid copper is a dependable and economical fungicide that can be used whenever copper fungicides are recommended for
More informationLIME SULPHUR INSECTICIDE MITICIDE FUNGICIDE COMMERCIAL DANGER: CORROSIVE TO EYES READ THE LABEL AND ATTACHED BOOKLET BEFORE USING
datapak group M fungicide LIME SULPHUR INSECTICIDE MITICIDE FUNGICIDE COMMERCIAL DANGER: CORROSIVE TO EYES READ THE LABEL AND ATTACHED BOOKLET BEFORE USING REGISTRATION NO. 16465 PEST CONTROL PRODUCTS
More informationAlcohol Consumption in Ireland 1986-2006 A Report for the Health Service Executive
Alcohol Consumption in Ireland 1986-2006 A Report for the Health Service Executive Prepared by Dr. Ann Hope This report should be referenced: Hope, A. (2007). Alcohol consumption in Ireland 1986-2006.
More informationBringing fruit, vegetables and plant products into the UK
Bringing fruit, vegetables and plant products into the UK Don t break the law Check the rules before you travel 1 There are very strict controls on what fruit, vegetable and plant products you can bring
More informationComputing our Future Computer programming and coding in schools in Europe. Anja Balanskat, Senior Manager European Schoolnet
Computing our Future Computer programming and coding in schools in Europe Anja Balanskat, Senior Manager European Schoolnet ABOUT THE SURVEY What do Ministries currently think about the topic? Curricula
More informationRepublic of Turkey Ministry of Economy, 2014 0
Republic of Turkey Ministry of Economy, 2014 0 FRESH FRUITS AND VEGETABLES PRODUCTION Vegetal production is the leading sector of Turkish agriculture, and vegetal perishables constitute the backbone of
More information41 T Korea, Rep. 52.3. 42 T Netherlands 51.4. 43 T Japan 51.1. 44 E Bulgaria 51.1. 45 T Argentina 50.8. 46 T Czech Republic 50.4. 47 T Greece 50.
Overall Results Climate Change Performance Index 2012 Table 1 Rank Country Score** Partial Score Tendency Trend Level Policy 1* Rank Country Score** Partial Score Tendency Trend Level Policy 21 - Egypt***
More information13 th Economic Trends Survey of the Architects Council of Europe
13 th Economic Trends Survey 13 th Economic Trends Survey of the Architects Council of Europe 13 th Economic Trends Survey Breakdown of responses COUNTRY ANSWERS France 1464 Belgium 399 Spain 365 Italy
More informationPopulation Aging in Developed Countries: Emerging Trends and Dynamics Wan He, Ph.D. Population Division U.S. Census Bureau
Population Aging in Developed Countries: Emerging Trends and Dynamics Wan He, Ph.D. Population Division U.S. Census Bureau This presentation is released to inform interested parties of population aging
More informationAnalysis of statistics 2015
Analysis of statistics 215 January 216 ECHR Analysis of Statistics 215 Table of Contents Overview of the Court s statistics in 215... 4 A. Number of new applications... 4 B. Applications disposed of judicially
More informationValue of production of agricultural products and foodstuffs, wines, aromatised wines and spirits protected by a geographical indication (GI)
Value of production of agricultural products and foodstuffs, wines, aromatised wines and spirits protected by a geographical indication (GI) TENDER N AGRI 2011 EVAL 04 Leaflet October 2012 The information
More informationBiological control of walnut blight: screening of antagonistic bacteria for Xanthomonas arboricola pv. juglandis and evaluation of their efficacy
Biological control of walnut blight: screening of antagonistic bacteria for Xanthomonas arboricola pv. juglandis and evaluation of their efficacy Hatice OZAKTAN Mine YAVAS Ahmet AKKÖPRÜ Emek ASLAN Adem
More informationBeer statistics. 2014 edition. The Brewers of Europe
Beer statistics 2014 edition The Brewers of Europe Beer statistics 2014 edition The Brewers of Europe Editor: Marlies Van de Walle 1st edition, October 2014 ISBN 978-2-9601382-3-8 EAN 9782960138238 1
More informationFact sheet: The Kyoto Protocol
Fact sheet: The Kyoto Protocol The Kyoto Protocol was adopted at the third Conference of the Parties to the UNFCCC (COP 3) in Kyoto, Japan, on 11 December 1997. The Protocol shares the objective and institutions
More informationCredit transfer to Customer account with AS "Meridian Trade Bank" EUR, USD free of charge * - 4.1.2. Other countries currency information in the Bank
Pricelist for individuals residents of Latvia SERVICES 4. TRANSFERS In the Bank PRICE LIST IN EUR Using «MultiNet» 4.1. 4.1.1. Credit transfer to Customer account with EUR, USD free of charge * 4.1.2.
More informationProposal from the Philippines for amendments to the Kyoto Protocol
UNITED NATIONS Distr. GENERAL FCCC/KP/CMP/2009/5 12 June 2009 Original: ENGLISH CONFERENCE OF THE PARTIES SERVING AS THE MEETING OF THE PARTIES TO THE KYOTO PROTOCOL Fifth session Copenhagen, 7 18 December
More information168/2014-4 November 2014. At risk of poverty or social exclusion 2 rate in the EU28, 2008-2013 (% of total population)
168/2014-4 November 2014 At risk of poverty or social exclusion in the EU28 More than 120 million persons at risk of poverty or social exclusion in 2013 Almost 1 out of every 4 persons in the EU in this
More informationSulfuric Acid 2013 World Market Outlook and Forecast up to 2017
Brochure More information from http://www.researchandmarkets.com/reports/2547547/ Sulfuric Acid 2013 World Market Outlook and Forecast up to 2017 Description: Sulfuric Acid 2013 World Market Outlook and
More information1. Perception of the Bancruptcy System... 2. 2. Perception of In-court Reorganisation... 4
Bankruptcy Systems and In-court Reorganisation of Firms, 2010 Content: 1. Perception of the Bancruptcy System... 2 2. Perception of In-court Reorganisation... 4 3. Perception of Creditor Committees, Fast
More informationCOMMUNICATION FROM THE COMMISSION
EUROPEAN COMMISSION Brussels, 17.9.2014 C(2014) 6767 final COMMUNICATION FROM THE COMMISSION Updating of data used to calculate lump sum and penalty payments to be proposed by the Commission to the Court
More informationERMInE Database. Presentation by Nils Flatabø SINTEF Energy Research. ERMInE Workshop 2 - Northern Europe Oslo, 1. November 2006
ERMInE Database Presentation by Nils Flatabø SINTEF Energy Research ERMInE Workshop 2 - Northern Europe Oslo, 1. November 26 Overview Content of the Ermine Database Electronic Questionnaire RTD&D Data
More informationElectricity, Gas and Water: The European Market Report 2014
Brochure More information from http://www.researchandmarkets.com/reports/2876228/ Electricity, Gas and Water: The European Market Report 2014 Description: The combined European annual demand for electricity,
More informationEuropean Research Council
ERC Starting Grant Outcome: Indicative statistics Reproduction is authorised provided the source ERC is acknowledged ERCEA/JH. ERC Starting Grant: call Submitted and selected proposals by domain Submitted
More informationINTERNATIONAL TRACKED POSTAGE SERVICE
INTERNATIONAL TRACKED POSTAGE SERVICE Index Expanding Internationally...03 The Post NL Service...04 How it works... 05 Post NL Rates...06 Transit times...07 Customer Service...08 Expanding Internationally
More informationEnergy prices in the EU Household electricity prices in the EU rose by 2.9% in 2014 Gas prices up by 2.0% in the EU
92/2015-27 May 2015 Energy prices in the EU Household electricity prices in the EU rose by 2.9% in 2014 Gas prices up by 2.0% in the EU In the European Union (EU), household electricity prices 1 rose by
More informationINTERNATIONAL TRADEMARK REGISTRATION UNDER THE MADRID PROTOCOL
INTERNATIONAL TRADEMARK REGISTRATION UNDER THE MADRID PROTOCOL Presented to The American Bar Association Spring Meeting Washington, D.C., April 24, 2013 Bruce Alexander McDonald BUCHANAN INGERSOLL & ROONEY
More informationSURVEY ON THE TRAINING OF GENERAL CARE NURSES IN THE EUROPEAN UNION. The current minimum training requirements for general care nurses
SURVEY ON THE TRAINING OF GENERAL CARE NURSES IN THE EUROPEAN UNION This survey serves as a background document for the discussion of the Commission's legislative proposal to modernize the minimum requirements
More informationLabour Force Survey 2014 Almost 10 million part-time workers in the EU would have preferred to work more Two-thirds were women
75/2015-27 April 2015 Labour Force Survey 2014 Almost 10 million part-time workers in the EU would have preferred to work more Two-thirds were women Among the 44.1 million persons in the European Union
More informationEuropean Bottled Water - Overview. Stewart Macintosh 16 th June 2011
European Bottled Water - Overview Stewart Macintosh 16 th June 211 The Big Picture Global Bottled Water M Litres 18, 16, 14, 12, 1, 8, 6, 4, 2, 2 21 22 23 24 25 26 27 28 29 21 Top 15 Bottled Water Markets
More informationERASMUS+ MASTER LOANS
ERASMUS+ MASTER LOANS Erasmus+ Master Loan: opening up access to more affordable lending for cross-border studies The Erasmus+ programme makes it possible for students who want to take a full Masters level
More informationERASMUS FOR YOUNG ENTREPRENEURS : A NEW EXCHANGE PROGRAMME
PRESS DOSSIER INDEX PRESS DOSSIER...1 INDEX...2 ERASMUS FOR YOUNG ENTREPRENEURS : A NEW EXCHANGE PROGRAMME...3 WHO CAN PARTICIPATE?...5 WHAT BENEFITS AND FOR WHOM?...6 HOW DOES IT WORK? STRUCTURE AND IMPLEMENTATION...7
More informationEmployee eligibility to work in the UK
Employee eligibility to work in the UK This document details legal requirements that apply to ALL new members of staff All employers in the UK are legally bound to comply with the Asylum and Immigration
More informationyour own success? Locate addresses exactly Visualise your company data Analyse connections Make the right decisions Use your full potential
PTV MAP&MARKET BASIC How can you map out your own success? Locate addresses exactly Visualise your company data Analyse connections Make the right decisions Use your full potential A unique combination
More information187/2014-5 December 2014. EU28, euro area and United States GDP growth rates % change over the previous quarter
187/2014-5 December 2014 This News Release has been revised following an error in the data for Gross Fixed Capital Formation. This affects both the growth of GFCF and its contribution to GDP growth. All
More informationConstructing a High-Performance Tertiary Education System in Finland
Constructing a High-Performance Tertiary Education System in Finland Jamil Salmi, 10 December 2014 The future of tertiary education? A world of science fiction? social and economic progress is achieved
More information99/2015-9 June 2015. EU28, euro area and United States GDP growth rates % change over the previous quarter
2005Q1 2005Q2 2005Q3 2005Q4 2006Q1 2006Q2 2006Q3 2006Q4 2007Q1 2007Q2 2007Q3 2007Q4 2008Q1 2008Q2 2008Q3 2008Q4 2009Q1 2009Q2 2009Q3 2009Q4 2010Q1 2010Q2 2010Q3 2010Q4 2011Q1 2011Q2 2011Q3 2011Q4 2012Q1
More informationPendulum Business Loan Brokers L.L.C. U.S. State Market Area
Pendulum Business Loan Brokers L.L.C. U.S. State Market Area Mission Statement Hiram R. Davis, the founder of Sweetwater Pipeline Company, has developed a Business Model to for our Merger & Acquisition
More informationFAO Regional Office (REU) - Budapest
Regional Office for Europe and Central Asia (REU) FAO Regional Office (REU) - Budapest Norbert Winkler-Ráthonyi (Forestry Officer) CI - SFM Regional Workshop Zagreb, Croatia, 26-27 March 2013 Regional
More informationECCE Standing Committee Education & Training
ECCE Standing Committee Education & Training Impact of the Bologna Process on Civil engineering education in Europe Prof. Iacint Manoliu 45 th ECCE meeting Bucharest, 11 May 2007 SCD Civil Engineering
More informationThe Guardianship Service
The Guardianship Service How can they help you? When you arrive in Belgium Are you under the age of 18 and have you arrived in Belgium without your father or mother? You are searching for support and accommodation
More informationFUSIONS Food waste data set for EU-28. New Estimates and Environmental Impact
FUSIONS Food waste data set for EU-28 New Estimates and Environmental Impact 15 October 2015 Food waste is an issue of importance to global food security and good environmental governance, directly linked
More informationWorld Solution Provider
GE Consumer & Industrial World Solution Provider GE imagination at work GE Six businesses aligned with our customers needs, acting as one company. Harnessing the imaginations of more than 300,000 people
More informationChecking the Effectiveness of Pest Control Measures
Checking the Effectiveness of Pest Control Measures Chris Hayes, PhD (Tampa) SE Technical Sales Manager & Mexico chayes@bioworksinc.com Cell: 585-820-6807 6/15/2015 1 Thanks Cultivate 15 Thanks to YOU,
More informationFor flowers, fruits & vegetables
Liquid Use to control a wide range of plant diseases ACTIVE INGREDIENT: Copper Octanoate (Copper Soap)....0.08% OTHER INGREDIENTS............. 99.92% TOTAL......................... 100.00% Metallic copper
More informationTHE ROLE OF PUBLIC SUPPORT IN THE COMMERCIALISATION OF INNOVATIONS
Flash Eurobarometer THE ROLE OF PUBLIC SUPPORT IN THE COMMERCIALISATION OF INNOVATIONS REPORT Fieldwork: January February 2014 Publication: May 2014 This survey has been requested by the European Commission,
More informationDormant Season. Of Dormant Oil Spray Apple scab, Pear scab, Powdery mildew. pre-pink, pink, calyx, 1st & 2nd cover spray.
99/2004 CLEAN CROP(R) LIME SULPHUR Lime Sulphur Insecticide Miticide Fungicide COMMERCIAL CAUTION CORROSIVE READ THE LABEL BEFORE USING REGISTRATION NO. 16465 PEST CONTROL PRODUCTS ACT GUARANTEE: Sulphide
More informationEUROPE 2020 TARGETS: RESEARCH AND DEVELOPMENT
EUROPE 2020 TARGETS: RESEARCH AND DEVELOPMENT Research, development and innovation are key policy components of the EU strategy for economic growth: Europe 2020. By fostering market take-up of new, innovative
More informationImplementing the cooperation mechanisms of the RES directive current status and open questions
Implementing the cooperation mechanisms of the RES directive current status and open questions Corinna Klessmann, Ecofys Germany RE-SHAPING Workshop, Vilnius, 16.05.2011 Supported by Intelligent Energy
More informationTechnical & Trade Schools Europe Report
Brochure More information from http://www.researchandmarkets.com/reports/3106479/ Technical & Trade Schools Europe Report Description: TECHNICAL & TRADE SCHOOLS EUROPE REPORT The Technical & Trade Schools
More informationPan- European region
Call for photographs in support of UNEP s assessment work in the PanEuropean region Background The United Nations Environment Programme (UNEP) is requesting interested persons to participate in this call
More informationTOYOTA I_SITE More than fleet management
EMPOWERING YOUR BUSINESS TOYOTA I_SITE More than fleet management www.toyota-forklifts.eu TOYOTA I_SITE More than fleet management Toyota I_Site is a unique combination of technology, information, expertise
More informationAdvanced Placement European History Summer Assignment 2015 Ms. Broffman
Advanced Placement European History Summer Assignment 2015 Ms. Broffman Welcome to AP European History. I look forward to working with you next year. The AP course and examination in European History are
More information2014 Fungicides for home garden use in New York State. Diseases: Anthracnose. Bacterial Canker Bitter rot. Apple black spot and scab.
APPLE Apple black spot and scab Bacterial Canker Bitter rot Black po Black rot Blossom and shoot blast Botryosphaeria (White rot) Botrytis rot Brooks fruit spot Brown rot Bullseye rot Cedar rust Fire blight
More informationTrends in the European Investment Fund Industry. in the First Quarter of 2016
Quarterly Statistical Release May 2016, N 65 This release and other statistical releases are available on Efama s website (www.efama.org) Trends in the European Investment Fund Industry in the First Quarter
More informationrelating to household s disposable income. A Gini Coefficient of zero indicates
Gini Coefficient The Gini Coefficient is a measure of income inequality which is based on data relating to household s disposable income. A Gini Coefficient of zero indicates perfect income equality, whereas
More informationWorld Consumer Income and Expenditure Patterns
World Consumer Income and Expenditure Patterns 2014 14th edi tion Euromonitor International Ltd. 60-61 Britton Street, EC1M 5UX TableTypeID: 30010; ITtableID: 22914 Income Algeria Income Algeria Income
More informationFunding and network opportunities for cluster internationalization
BSR Innovation Express: Cluster- to- Cluster Conference Funding and network opportunities for cluster internationalization Jens Peter Vittrup Special Adviser Email: jpv@ai.dk Why international R&I cooperation?
More informationBrochure More information from http://www.researchandmarkets.com/reports/1339929/
Brochure More information from http://www.researchandmarkets.com/reports/1339929/ The 2011 World Forecasts of Machine Tools That Remove Material by Laser or Light, Photon, Ultrasonic, Electro-Discharge,
More informationERASMUS+ MASTER LOANS
Ref. Ares(2015)660570-17/02/2015 ERASMUS+ MASTER LOANS Erasmus+ Master Loan: opening up access to more affordable lending for cross-border studies The Erasmus+ programme makes it possible for students
More informationTechnical & Trade School Lines Europe Report
Brochure More information from http://www.researchandmarkets.com/reports/3106478/ Technical & Trade School Lines Europe Report Description: TECHNICAL & TRADE SCHOOL LINES EUROPE REPORT The Technical &
More informationEMBO Short Term Fellowships Information for applicants
EMBO Short Term Fellowships Information for applicants - Purpose - Duration - Eligibility - How to apply - Selection procedure - End of fellowship report - Benefits - EMBC Member States - Contact details
More informationDublin, March 2013. EPSO Network of Experts in the field of Personnel Selection 14th March 2013
Dublin, March 2013 EPSO Network of Experts in the field of Personnel Selection 14th March 2013 On-going and upcoming competitions AD2012 by Citizenship AD2012 Citizenship %EU Population validated application
More informationDirect Life Insurance Carrier Lines Europe Report
Brochure More information from http://www.researchandmarkets.com/reports/3106712/ Direct Life Insurance Carrier Lines Europe Report Description: DIRECT LIFE INSURANCE CARRIER LINES EUROPE REPORT The Direct
More informationAdobe Public Relations (PR) Guidelines
Adobe Public Relations (PR) Guidelines Adobe Partner Connection Reseller Program and Adobe Partner Connection Distributor Program Thank you for participating in the Adobe Partner Connection Reseller or
More informationBringing fruit, vegetables and plant products into the UK. Don t break the law Check the rules before you travel
Bringing fruit, vegetables and plant products into the UK Don t break the law Check the rules before you travel There are very strict controls on what fruit, vegetable and plant products you can bring
More informationFOLPAN 80 WDG FUNGICIDE
GROUP M FUNGICIDE FOLPAN 80 WDG FUNGICIDE COMMERCIAL A water dispersible granular fungicide for the control of a number of fungus diseases on certain fruit, vegetables, ornamental and other crops. REGISTRATION
More informationTomato Disease Management in Greenhouses
Purdue Extension publication BP-197-W University of Kentucky Cooperative Extension publication ID-233 Vegetable Diseases Tomato Disease Management in Greenhouses Photos by the authors Authors Daniel S.
More informationWaste. Copenhagen, 3 rd September 2014. Almut Reichel Project Manager Sustainable consumption and production & waste, European Environment Agency
Waste Copenhagen, 3 rd September 2014 Almut Reichel Project Manager Sustainable consumption and production & waste, European Environment Agency Waste and material resources MAWP Strategic Area 1.9 Objective
More informationAbout us. As our customer you will be able to take advantage of the following benefits: One Provider. Flexible Billing. Our Portal.
About us At RoamingExpert we specialise in mobile roaming tariffs which are tailored to the specific needs of the yachting industry. Our unique offering generates significant savings when compared to standard
More informationAMADEUS: Analyse MAjor Databases from EUropean Sources - A financial database of 4 million European companies, including Eastern Europe MODULE.
AMADEUS http://amadeus.bvdep.com/ip AMADEUS: Analyse MAjor Databases from EUropean Sources - A financial database of 4 million European companies, including Eastern Europe MODULE. General AMADEUS contains
More informationHow To Understand Factoring
EIF Project "Jeremie" General Report on Factoring 1 Market analysis on Factoring in EU 25+2 prepared by International Factors Group (IFG) for European Investment Fund (EIF) project JEREMIE Preliminary
More informationPART TWO POLICIES FOR ADJUSTMENT AND GROWTH
PART TWO ICIES FOR ADJUSTMENT AND GROWTH Economic Survey of Europe, 22 No. 1 CHAPTER 4 TECHNOLOGICAL ACTIVITY IN THE ECE REGION DURING THE 199s While the task of estimating the contribution of technical
More informationForeign Obligations Notification Process
Foreign Obligations Notification Process Santiago Aguilar Nuclear Regulatory Commission 1 Agreements for Peaceful Nuclear Cooperation Current agreements with the IAEA, 21 countries, and Taiwan. The agreements
More informationMalta Companies in International Tax Structuring February 2015
INFORMATION SHEET No. 126 Malta in International Tax Structuring February 2015 Introduction Malta is a reputable EU business and financial centre with an attractive tax regime and sound legislative framework.
More informationWind Power in Germany in 2014
Renewables International www.renewablesinternational.net Wind Power in Germany in 2014 Bernard CHABOT BCCONSULT, Garbejaire B107, 06560 VALBONNE, France Email: Bernard_Chabot@yahoo.fr Content Scope, main
More informationBusiness Cooperation Database Profile Extraction
Business Cooperation Database Profile Extraction Produced the 23/05/2013 General Information Profile ID 20111230018 Summary Creation Date 30/12/2011 Last Update 12/01/2012 Expiration Date 02/01/2014 Intermediary
More informationProviding Safe and Effective Pest Management Solutions for Specialty Crop Growers
2008 Year in Review Providing Safe and Effective Pest Management Solutions for Specialty Crop Growers 2008 IR-4 Accomplishments IR-4 Data Led To... Food Use In 2008 the US Environmental Protection Agency
More informationApplication Form: Receptionist / PA to the Senior Leadership Team
Application Form: Receptionist / PA to the Senior Leadership Team This application form is written in BLACK ink. Please answer the questions in dark blue and return electronically to Lesley Starkes, Finance
More information193/2014-15 December 2014. Hourly labour costs in the EU28 Member States, 2012 (in )
193/2014-15 December 2014 Labour Cost Survey 2012 in the EU28 Labour costs highest in the financial and insurance sector Three times higher than in the accommodation and food sector In 2012, average hourly
More informationInternational Hints and Tips
International Hints and Tips Content Q: What is the cut off time for processing International payments? A: International payments must be submitted and fully approved within the cut off time indicated
More informationINNOBAROMETER 2015 - THE INNOVATION TRENDS AT EU ENTERPRISES
Eurobarometer INNOBAROMETER 2015 - THE INNOVATION TRENDS AT EU ENTERPRISES REPORT Fieldwork: February 2015 Publication: September 2015 This survey has been requested by the European Commission, Directorate-General
More informationGood practice of dissemination and exploitation results in Latvia
Good practice of dissemination and exploitation results in Latvia Dr.phys. Gunta Šlihta Vice-director, Institute of Physical Energetics Rīga, / 03 / 03 Methods of transfer of project results in the Baltic
More informationADR Programme. ADR 2011 Amendments. Soren Christiansen Special Advisor IRU Academy. IRU Academy ADR Programme 1
ADR Programme ADR 2011 Amendments Soren Christiansen Special Advisor IRU Academy IRU Academy ADR Programme 1 46 ADR Contracting Parties (Turkey joined on 22 February 2010) Albania, Andorra, Austria, Azerbaijan,
More informationMainStay Funds Income Tax Information Notice
The information contained in this brochure is being furnished to shareholders of the MainStay Funds for informational purposes only. Please consult your own tax advisor, who will be most familiar with
More informationReport on Government Information Requests
Report on Government Information January 1 - June 30, 2015 Apple takes our commitment to protecting your data very seriously and we work incredibly hard to deliver the most secure hardware, software and
More informationSix greenhouse gases covered by the United Nations Framework Convention on Climate Change (UNFCCC) and its Kyoto Protocol are:
Fact sheet: The need for mitigation United Nations Framework Convention on Climate Change Along with adaptation, mitigation is one of the two central approaches in the international climate change process.
More information