Safety data sheet according to 1907/2006/EC, Article 31

Transcription

1 Page 1/6 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier Article number: Relevant identified uses of the substance or mixture and uses advised against Sector of Use SU20 Health services Application of the substance / the mixture In-vitro laboratory reagent or component 1.3 Details of the supplier of the safety data sheet Manufacturer/Supplier: Bio-Rad Laboratories Ltd. Bio-Rad House Maxted Road Hemel Hempstead, Herts HP2 7DX United Kingdom phone: fax: e:mail contact: techsupport.uk@bio-rad.com Information department: Technical services, customer support. techsupport.uk@bio-rad.com 1.4 Emergency telephone number: SECTION 2: Hazards identification 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Acute Tox. 4 H332 Harmful if inhaled. 2.2 Label elements Labelling according to Regulation (EC) No 1272/2008 The product is classified and labelled according to the CLP regulation. Hazard pictograms GHS07 Signal word Warning Hazard-determining components of labelling: methanol Hazard statements H332 Harmful if inhaled. Precautionary statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P312 Call a POISON CENTER/doctor if you feel unwell. (Contd. on page 2)

2 Page 2/6 (Contd. of page 1) SECTION 3: Composition/information on ingredients 3.2 Chemical characterisation: Mixtures Description: Mixture of the substances listed below with nonhazardous additions. Dangerous components: CAS: EINECS: sucrose, pure substance with a Community workplace exposure limit % CAS: EINECS: methanol Additional information Contains human sourced and/or potentially infectious components. Contains added constituents of animal origin. For the wording of the listed hazard phrases refer to section 16. Flam. Liq. 2, H225 Acute Tox. 3, H301; Acute Tox. 3, H311; Acute Tox. 3, H331 STOT SE 1, H % SECTION 4: First aid measures 4.1 Description of first aid measures General information No special measures required. After inhalation Supply fresh air; consult doctor in case of complaints. After skin contact Immediately wash with water and soap and rinse thoroughly. Generally the product does not irritate the skin. After eye contact Rinse opened eye for several minutes under running water. Then consult a doctor. After swallowing Rinse mouth with water. Seek medical attention and appropriate follow-up. 4.2 Most important symptoms and effects, both acute and delayed Eye irritaion SECTION 5: Firefighting measures 5.1 Extinguishing media Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. 5.3 Advice for firefighters Protective equipment: No special measures required. SECTION 6: Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures Handle as potentially infectious. 6.2 Environmental precautions: Keep contaminated washing water and dispose of appropriately. Do not allow to enter sewers/ surface or ground water. 6.3 Methods and material for containment and cleaning up: Absorb liquid components with liquid-binding material. Pick up mechanically. Clean the affected area carefully; suitable cleaners are: Disinfectant (Contd. on page 3)

3 Page 3/6 6.4 Reference to other sections See Section 13 for disposal information. (Contd. of page 2) SECTION 7: Handling and storage 7.1 Precautions for safe handling No special precautions are necessary if used correctly. Information about protection against explosions and fires: No special measures required. 7.2 Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: According to product specification Information about storage in one common storage facility: Not required. Further information about storage conditions: Refer to package insert for additional information regarding storage conditions. * SECTION 8: Exposure controls/personal protection Additional information about design of technical systems: No further data; see item Control parameters Components with limit values that require monitoring at the workplace: sucrose, pure WEL Short-term value: 20 mg/m³ Long-term value: 10 mg/m³ methanol WEL Short-term value: 333 mg/m³, 250 ppm Long-term value: 266 mg/m³, 200 ppm Sk Additional information: The lists that were valid during the creation were used as basis. 8.2 Exposure controls Personal protective equipment General protective and hygienic measures Follow the usual biosafety practices for handling potentially infectious materials. The usual precautionary measures should be adhered to when handling chemicals. Breathing equipment: Not required. Protection of hands: Protective gloves. Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Synthetic gloves Penetration time of glove material The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Safety glasses Body protection: Protective work clothing. (Contd. on page 4)

4 Page 4/6 (Contd. of page 3) SECTION 9: Physical and chemical properties 9.1 Information on basic physical and chemical properties General Information Appearance: Form: Fluid Colour: Various colours Odour: Odourless ph-value: Change in condition Melting point/melting range: undetermined Boiling point/boiling range: undetermined Flash point: Not applicable Danger of explosion: Product does not present an explosion hazard. Density: Not determined Solubility in / Miscibility with Water: Solvent content: Organic solvents: 0.8 % Solids content: 7.4 % Fully miscible SECTION 10: Stability and reactivity 10.1 Reactivity 10.2 Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications Hazardous decomposition products: No dangerous decomposition products known SECTION 11: Toxicological information 11.1 Information on toxicological effects Acute toxicity Harmful if inhaled. LD/LC50 values that are relevant for classification: methanol Oral LD mg/kg (rat) Dermal LD mg/kg (rat) Primary irritant effect: Skin corrosion/irritation Based on available data, the classification criteria are not met. Serious eye damage/irritation Based on available data, the classification criteria are not met. Respiratory or skin sensitisation Based on available data, the classification criteria are not met. CMR effects (carcinogenity, mutagenicity and toxicity for reproduction) Germ cell mutagenicity Based on available data, the classification criteria are not met. (Contd. on page 5)

5 Page 5/6 Carcinogenicity Based on available data, the classification criteria are not met. Reproductive toxicity Based on available data, the classification criteria are not met. STOT-single exposure Based on available data, the classification criteria are not met. STOT-repeated exposure Based on available data, the classification criteria are not met. Aspiration hazard Based on available data, the classification criteria are not met. (Contd. of page 4) SECTION 12: Ecological information Additional ecological information: General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. SECTION 13: Disposal considerations 13.1 Waste treatment methods Recommendation Dispose of waste in accordance to applicable national, regional, or local regulations. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agent: Water, if necessary with cleansing agents. SECTION 14: Transport information 14.1 UN-Number ADR, ADN, IMDG, IATA Void 14.2 UN proper shipping name ADR, ADN, IMDG, IATA Void 14.3 Transport hazard class(es) ADR, ADN, IMDG, IATA Class Void 14.4 Packing group ADR, IMDG, IATA Void UN "Model Regulation": Void SECTION 15: Regulatory information 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture Directive 2012/18/EU Named dangerous substances - ANNEX I methanol (Contd. on page 6)

6 Page 6/6 National regulations Technical instructions (air): Class Share in % I (Contd. of page 5) Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water Chemical safety assessment: A Chemical Safety Assessment has not been carried out. SECTION 16: Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Relevant phrases H225 Highly flammable liquid and vapour. H301 Toxic if swallowed. H311 Toxic in contact with skin. H331 Toxic if inhaled. H370 Causes damage to organs. Department issuing SDS: Environmental Health and Safety. Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) Abbreviations and acronyms: ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods DOT: US Department of Transportation IATA: International Air Transport Association ACGIH: American Conference of Governmental Industrial Hygienists EINECS: European Inventory of Existing Commercial Chemical Substances ELINCS: European List of Notified Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) NFPA: National Fire Protection Association (USA) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent PBT: Persistent, Bioaccumulative and Toxic vpvb: very Persistent and very Bioaccumulative NIOSH: National Institute for Occupational Safety OSHA: Occupational Safety & Health SVHC: Substances of Very High Concern Flam. Liq. 2: Flammable liquids, Hazard Category 2 Acute Tox. 3: Acute toxicity, Hazard Category 3 Acute Tox. 4: Acute toxicity, Hazard Category 4 STOT SE 1: Specific target organ toxicity - Single exposure, Hazard Category 1 * Data compared to the previous version altered.