Business opportunity during the allergy season...

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1 Business opportunity during the allergy season... Blink, Refresh, Enjoy...with DAILIES AquaComfort Plus contact lenses

2 DAILIES AquaComfort Plus contact lenses all day comfort, all allergy season long Added HPMC for a comfort drop effect Only DAILIES Plus contact lenses are bathed in a saline solution with added HPMC 4 for a comfort drop effect HPMC is a high viscosity polymer often found as the primary ingredient in comfort drops used to relieve eye discomfort HPMC provides an additional cushioning effect when inserting the lens for truly superior comfort upon insertion. Ideal for first-time wearers Lens Tear film Moisturising Agents DAILIES Plus contact lenses release blink-activated moisture exactly where it is needed throughout the day. Two ingredients, PEG and PVA work in synergy to continuously lubricate the lens and deliver outstanding all-day comfort Moisturizing agents are gradually released over a 20-hour period 5 Pre-lens Non-invasive Tear Breakup Time (seconds) Superior Tear Film Stability with DAILIES PLUS contact lenses 1* 20s s s. 5s. 0s. p<0.05 Time Since Lens Insertion (hours) DAILIES PLUS Focus DAILIES All Day Comfort 1 DAY ACUVUE MOIST SofLens Daily Disposable 8h. 12h. 16h. DAILIES Plus contact lenses provide superior tear film stability* 6, a key benefit for your customers DAILIES Plus contact lenses work with the eye s natural blinking, releasing PVA and helping to maintain a stable tear film all day A stable tear film is essential for quality of vision, comfort and a successful lens-wearing experience DAILIES AquaComfort Plus offers outstanding tear film stability 6 for all day comfort

3 Facts about seasonal ocular allergy Many factors such as pollution, dust, animal dander and seasonal pollen can cause seasonal allergies Studies have highlighted that seasonal allergic conditions are under-diagnosed and under-treated 1 Over 30% of the population are affected by ocular allergy season 2 By 2015 it is expected that 50% of the population will be affected by ocular allergy season 3 Seasonal ocular allergies can be extremely uncomfortable and may disrupt day-to-day activities 3 Seasonal airborn allergens such as pollen, dust and animal dander come in contact with the cornea and disrupt the normal tear film 3 The graph below shows the type and severity of ocular allergy season symptoms commonly experienced by seasonal allergy sufferers. These symptoms have implications for Eye Care Professionals when selecting the right lens for customers. severe Symptoms of seasonal ocular allergy Symptom severity moderate slight none Dryness Itchiness Burning Stinging Watering Redness Desire to rub Mean Variability Symptom Occular allergy symptom severity of all sufferers. Error bars = 1 S.D. n = 126

4 It is routine to ask customers about seasonal allergy......how does that influence your clinical decision making? Ocular allergy season & contact lenses Discomfort Historically, contact lens wearers who suffer with seasonal ocular allergy have a higher level of contact lens discomfort. 1 Drop-Out Seasonal ocular allergy is a common cause of soft contact lens wear drop-out. 3 Seasonal allergic conjunctivitis has been shown to result in tear film instability 1

5 Proven: DAILIES PLUS TM contact lenses are ideal for wearers who experience symptoms of seasonal ocular allergies 1 A study examined the clinical performance of market leading contact lenses when exposed to pollen No lens Change in CCLRU grading with exposure to pollen DAY ACUVUE MOIST embedded moisturising agent DAILIES PLUS TM enhanced moisture release through blink activation Variability 0.0 Bulbar redness Limbal redness Palpebral redness Corneal Staining Bulbar Staining Signs All differences between MOIST and DAILIES PLUS TM were statistically significant (P<0.05) especially Bulbar Redness (P<0.01) DAILIES AquaComfort Plus contact lenses help relieve the signs and symptoms of seasonal allergic conjunctivitis, including stinging, redness and watering, in contact lens patients 7

6 Superior comfort with DAILIES AquaComfort Plus and more successful fits for your business 8 Superior comfort upon insertion** 8,9 Blink activated moisturizing agents for all day comfort DAILIES Plus helps to relieve the signs and symptoms of seasonal ocular allergies 7 which means you can have confidence in fitting your customers with DAILIES Plus Contact your Alcon* sales representative and order trials of DAILIES Plus TM contact lenses today Blink, Refresh, Enjoy * Compared to 1-day ACUVUE MOIST, SofLens Daily Disposable, and Focus DAILIES All Day Comfort TM contact lenses. ** versus 1-day ACUVUE TruEye contact lenses, among first-time contact lens wearers and existing daily disposable wearers. References: 1. Lemp M. (2008). Clinical performance of Contact Lenses and Allergy. 2. Usage & Attitude Study, Contact Lenses Country Report 2010, Great Britain, MW Research. 3. Wolffsohn J, Emberlin J. (2011) Objective clinical performance of role of contact lenses in relieving ocular allergy. Contact Lens & Anterior Eye. 4. CIBA VISION data on file, Among leading daily disposable lenses. 5. Laboratory study comparing release profiles; significance demonstrated at the 0.05 level; CIBA VISION data on file Wolffsohn J, Hunt O, Chowddhury A. Objective clinical performance of comfort enhanced daily disposable soft contact lenses. Contact Lens & Anterior Eye. 2010; 33: Steigemeier MJ, Fahmy M, Tomas S. Beating back SAC. Optometric Management. 2008; 43(9): In a randomized, parallel group clinical study at 26 sites with 291 neophyte contact lens wearers who were masked to the sponsor; significance demonstrated at the 0.05 level, CIBA VISION data on file, CIBA VISION data on file, Among leading daily disposable lenses Alcon

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