Microbiology in the MLS Master. Justine Collier March 2013

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1 Microbiology in the MLS Master Justine Collier March 2013

2 Job perspectives as a microbiologist! In public agencies: -! Research (universities, institutes, hospitals!) -! Teaching ( schools, HES, universities!) -! Administration (regulatory agencies,!) -! Waste and water treatment -!!! In the industry: -! Biotech companies -! Pharmaceutical companies -! Medical analysis -! Food industry (dairy products, beer,!) -! Quality control -!!

3 MLS Master, mention «!Microbiology!» Why? If you have a special interest in Microbial Sciences and wish this to appear on your MLS degree and CV (may be a plus if you apply to microbiology-related jobs in the industry or to microbiologyoriented PhD programs) How? 1.! Choose minimum 8 optional courses linked with Microbiology (1st and 2 nd semesters) = minimum 12 ECTS total 2.! Choose a Master thesis that is tagged «!Microbiology!» (mainly at the DMF or at the IMUL) For your First step project, you can choose any project you want.

4 Optional courses tagged as «!Microbiology!»! 1st semester: -! Understanding bacterial metabolism from a genomic perspective -! Immunology with relevance to infectious diseases -! Advanced bacterial genetics and small RNA regulation -! Virus-host interactions -! Fungal virulence and pathogenicity! 2 nd semester: -! Anti-infective agents -! Bacterial virulence and pathogenesis -! Cytoskeleton: from microbes to man -! Edidemiology -! Microbes as tools in experimental biology -! Microbial ecology -! Viral pathogenesis and emerging viruses More fundamental! More medical! Total = 18 ECTS! but you just need to take 12 ECTS to get the mention «Microbiology»

5 The DMF and the IMUL: two complementary Microbiology departments at UNIL Department of Fundamental Microbiology Institute of Microbiology Mainly non-medical research Mainly biomedical research

6 Microbial life sciences Viruses Bacteria Fungi

7 Viruses that we study (1) -! Human immunodeficiency virus (HIV) Telenti (IMUL): Why are some people more or less sensitive to HIV? Ciuffi (IMUL): How do retroviruses integrate into the host genome as part of their life cycle? -! Hepatitis B and C viruses Moradpour (IMUL): Which types of molecular interactions are there between the HCV and its host?

8 Viruses that we study (2) -! Lassa virus (hemorrhagic fever) Kunz (IMUL): How does the Lassa virus invade a human cell, and how can this be blocked? -! Human papilloma virus (cervix cancer) Nardelli-Haefliger (IMUL): How can we use immunotherapy to fight cancers?

9 Bacteria that we study (1)! Staphylococcus aureus (pneumonia, meningitis, endocarditis) Moreillon/Entenza (DMF): How can Staphylocci become multi-drug resistant and what are their mechanisms of infection?! Chlamydia-like intracellular bacteria (pneumonia and miscarriage) Greub (IMUL): Are Chlamidia-like bacteria new agents of pneumonia or miscarriage?! Caulobacter crescentus Collier (DMF): How is the bacterial cell cycle regulated?

10 Bacteria that we study (2)! Escherichia coli and Sphingomonas wittichii Van der Meer (DMF): Can we create bacterial biosensors or bioremediators?! Pseudomonas Van der Meer (DMF): Which are the mechanisms for horizontal gene transfers? Lapouge (DMF): How is Pseudomonas adapting to environmental changes, in particular to different food sources? Keel (DMF): How do pseudomonads protect plants from diseases? Reimmann (DMF): How do bacteria communicate with each other and with their hosts?

11 Fungi that we study! Pneumocystis jiroveccii (pneumonia) Hauser (IMUL): Which new potential drug target genes exist in P. jiroveccii?! Candida albicans (candiasis) Sanglard (IMUL): Which are the molecular mechanisms for drug resistance and tolerance by Candida species?! Fission yeast Martin (DMF): How is the yeast cell cycle regulated and how is cell polarity established?! Budding yeast Pellet (DMF): How is signal transduction taking place in single yeast cells?

12 Great diversity of subjects! Pathogenic/ non pathogenic models: Molecular Cellular Follow-up CUSO Doctoral Program in Microbial Sciences : microbiologie Environment/Human

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