20 th Belgian Congress on Rheumatology

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1 20 th Belgian Congress on Rheumatology Organised by the Belgian Royal Society for Rheumatology September 2016 Hotel Van der Valk, Gosselies Preliminary Programme Scientific Organiser Patrick Verschueren Local Organising Committee Silvano Dall Armellina Dimitri Jardinet Laurent Méric de Bellefon

2 Scientific Organiser Patrick Verschueren UZ Leuven Herestraat Leuven Local Organising Committee Silvano Dall Armellina Dimitri Jardinet Laurent Méric de Bellefon La Clinique Notre-Dame de Grâce Gosselies (CNDG) Chaussée de Nivelles Gosselies Venue Van der Valk Hotel Charleroi Airport Chaussée de Courcelles Gosselies Congress Secretariat Medicongress Services Noorwegenstraat 49 B-9940 Evergem, Belgium Phone: +32 (0) Fax: +32 (0) Welcome Address Dear colleagues, The Royal Belgian Society for Rheumatology takes great pleasure in announcing the 20 th Belgian Congress on Rheumatology. Indeed, we are celebrating the 20 th anniversary of our national congress. This anniversary edition will take place in Gosselies on September 28, 29 and 30. The scientific programme has been coordinated by Patrick Verschueren, who has put together a varied and interesting programme with state-of-the-art keynote lectures and oral communications. Again a quiz is organised, a poster tour and 2 workshops for early risers. Furthermore 10 Updates in Therapeutics are scheduled. After a successful first session last year, we are delighted to announce that the Thieves Market is scheduled again this year. As you will know the Thieves Market is dedicated to assistants and young rheumatologists. Remarkable clinical cases will be the core of this special session. We hope to welcome you to the anniversary edition of the congress and remain, Yours sincerely, Silvano Dall Armellina Dimitri Jardinet Laurent Méric de Bellefon

3 Wednesday, September 28 Young Investigator Meeting Chairs: Ruth Wittoek (UGent) and Olivier Malaise (ULG) A20 inhibition of STAT1 expression in myeloid cells: 1 novel endogenous regulatory mechanism preventing development of enthesitis Katelijne De Wilde, A. Martens, S. Lambrecht, P. Jacques, M.B. Drennan, K. Debusschere, S. Govindarajan, J. Coudenys, E. Verheugen, F. Windels, R. Lories, D. McGonagle, R. Beyaert, G. van Loo, D. Elewaut S100 DAMPs: Drivers of disease in arthritis by myeloid deficiency of A20? Karlijn Debusschere, H. Cypers, T. Vogl, J. Roth, G. Van Loo, M. Drennan, D. Elewaut Histone methyltransferase DOT1L is essential for growth and homeostasis of the articular cartilage Silvia Monteagudo, F. Cornelis, P. Yibmantasiri, L. Storms, R.J. Lories The isotype distribution of antibodies against novel UH-RA peptides in rheumatoid arthritis Liesbeth De Winter, P. Geusens, J. Lenaerts, J. Vanhoof, P. Stinissen, V. Somers The paracaspase MALT1 plays a central role in the pathogenesis of rheumatoid arthritis Elisabeth Gilis, J. Staal, R. Beyaert, D. Elewaut Autoimmune profile of patients with idiopathic inflammatory myopathy at the University Hospitals Leuven Jean-Baptiste Vulsteke, X. Bossuyt, D. Blockmans, R. Westhovens, J. Lenaerts, E. De Langhe A cholecystokinin receptor antagonist inhibits chondrocyte hypertrophy and protein kinase a activity decrease induced by activation of GPR22 Laura-An Guns, D. Calebiro, M.J. Lohse, R.J. Lories, F. Cailotto Fecal calprotectin as a new diagnostic tool in diagnosing spondyloarthropathies Margot Van Geem, L. Van Hoovels, B. Vander Cruyssen, M. Van Hoydonck, I. Ravelingien, M. Stubbe Wednesday, September Welcome Lunch Opening Ceremony and Award Presentation Patrick Verschueren, KUL, René Westhovens, KUL & Xavier Janssens, Gent SESSION 1 Chairpersons: Ilse Hoffman (GZA) and Isabelle Peene (AZ-Sint-Jan) Vesalius Lecture Introduction by Nele Caeyers, ReumaNet My view on rheumatology: From 1986 to 2016 Tore Kvien, Oslo, Norway Abstract Presentations Randomized, placebo-controlled trial to evaluate clinical efficacy and structure modifying properties of subcutaneous etanercept in patients with erosive inflammatory hand osteoarthritis M. Kloppenburg, R. Ramonda, W.-Y. Kwok, K. Bobacz, D. Elewaut, P. Frallonardo, T.W. Huizinga, F. Kroon, J. Smolen, B. Vander Cruyssen, R. Wolterbeek, L. Punzi, G. Verbruggen, Ruth Wittoek Secondary bone size deficit in patients with Ehlers-Danlos syndrome Charlotte Verroken, P. Calders, I. De Wandele, F. Malfait, H. Zmierczak, S. Goemaere, J.M. Kaufman, B. Lapauw, L. Rombaut Calprotectin as a multipotent biomarker in juvenile idiopathic arthritis Céline La, P. Stordeur, J. Smet, D. Franchimont, B. Lauwerys, P. Quoc Lê, L. Goffin, C. Boulanger, A. Ferster, J.P. Brasseur, B. Brasseur, D. Tuerlinckx, D. Spruyt, J. Rasschaert, V. De Maertelaer, S. Kleimberg, T. Sokolova, P. Durez, V. Badot on behalf of the CAP48 investigators Quiz Quizmasters: Isabelle Peene (AZ Sint-Jan) & Yves Piette (AZ Sint-Jan) Coffee Break

4 Wednesday, September 28 SESSION 2 Chairpersons: Ellen De Langhe (KUL) and Marie Vanthuyne (UCL) Physical activity in axial spondyloarthropathy Thijs Swinnen, KUL Update in Therapeutics Eli Lilly Outcome measurement using the PROMIS tool Leo Roorda, Amsterdam, The Netherlands Update in Therapeutics Celgene Update in Therapeutics Roche Clinical aspects of glucocorticoids in the treatment of RA Frank Buttgereit, Berlin, Germany General Assembly Walking Dinner SESSION 3 - Ethics & Economy Chairpersons: Silvano Dall Armellina (CNDG) and Laurent Méric de Bellefon (CNDG & UCL) Use of off label drugs (including those submitted to reimbursement), practical aspects Greet Musch, FAGG-AFMPS Viewpoint of the patients on care Nele Caeyers, ReumaNet Care of patients with rare rheumatic conditions in Belgium Bernard Lauwerys, UCL & Working Group Rare Diseases Update on Tardis Patrick Durez, UCL & Patrick Verschueren, KUL Thursday, September Workshop 1 How to prescribe physiotherapy? Dieter Van Assche (KUL) SESSION 4 Chairpersons: Valerie Badot (ULB) and Vanessa Smith (UGent) Ultrasound based disease activity scoring Maria Stoenoiu, UCL Abstract Presentations Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis (PAAND): Preliminary results of a proof-of-concept trial with anakinra Lien Van Eyck, E. De Langhe, I. Jéru, E. Van Nieuwenhove, V. Lagou, P.J. Baker, J. Garcia-Perez, J. Dooley, L. De Somer, R. Sciot, P.Y. Jeandel, J. Ruuth-Praz, B. Copin, M. Medley-Hashim, A. Megarbane, S. Savic, A. Goris, S. Amselem, S. Masters, A. Liston, C. Wouters Analysis of occupational exposure and clinical characteristics of male patients with systemic sclerosis, included in the Belgian Systemic Sclerosis cohort Evelien De Decker, M. Vanthuyne, D. Blockmans, B. Nemery, F. Houssiau, R. Westhovens, J. Lenaerts, E. De Langhe STAT3 phosphorylation mediates the stimulatory effects of interferon alpha on B cell differentiation and activation in SLE Julie Ducreux, F. Aleva, A. De Groof, A. Ferster, F. van de Veerdonk, F.A. Houssiau, B.R. Lauwerys Update on Jak inhibitors in rheumatoid arthritis René Westhovens, KUL Coffee Break Panel discussion: Costs of drugs in rheumatology Moderator: René Westhovens (KUL) Panel: Jo De Cock (Riziv), Chris Van Haecht (CM) and Herman Van Eeckhaut (Pharma.be) End of day

5 Thursday, September 29 SESSION 5 Chairpersons: Anne Durnez (UCL, CHIREC, AZ Jan Portaels) and Maria Stoenoiu (UCL) Update in Therapeutics Novartis Blocking IL-17 in spondyloarthritis An overview of the available data Jürgen Braun, Bochum, Germany Update in Therapeutics AbbVie Patient tailored adherence interventions: From evidence to practice Fabienne Dobbels, Leuven, Belgium Belgian Rheumatology in Review (Clinical) Béatrice André, ULG & Ilse Hoffman, GZA Lunch Poster Tour General Assembly SESSION 6 Chairpersons: Bert Vander Cruyssen (St. Jozef Kliniek Bornem, OLV Aalst) and Muriel Stubbe (OLV Aalst) Update in Therapeutics - Janssen Gastroenterology, rheumatology and dermatology: Joining forces against co-morbidities Catherine Reenaers, ULG Thursday, September 29 SESSION 7 Chairpersons: Christian Von Frenckel (ULG) and Liesbet Van Praet (UGent) Chronic pain, lessons for the rheumatologist Mira Meeus, UGent & UAntwerpen Abstract Presentations Does BMI increase in patients with early rheumatoid arthritis when treated with short-term glucocorticoid remission induction schemes? Diederik De Cock, R. Westhovens, V. Stouten, K. Van der Elst, J. Joly, P. Verschueren Anti-carbamylated protein antibodies in belgian early arthritis patients: First results from the CAP48 RA cohort Paschalis Sidiras, J. Rasschaert, D. Spruyt, S. Kleimberg, T. Sokolowa, M. Stoeniou, L. Méric de Bellefon, S. Schreiber, L. Dujardin, P. Durez, B. Lauwerys, V. Badot on behalf of the CAP48 investigators Assessment of the burden of comorbidities by the Rheumatic Disease Comorbidity Index in early rheumatoid arthritis patients at disease onset: Data from the CareRA study Veerle Stouten, D. De Cock, R. Westhovens, J. Joly, K. Van der Elst, P. Verschueren Update in Therapeutics - BMS End of day Belgian Rheumatology in Review (Basic) Ellen De Langhe, KUL & Muriel Stubbe, OLV Aalst Coffee Break

6 Friday, September Workshop 2 Hands-on ultrasound imaging of the hand Maria Stoenoiu (UCL), Anne Durnez (UCL, AZ Jan Portaels Vilvoorde) & Laurent Méric de Bellefon (UCL, CNDG, CHU, Saint-Pierre Brussels) On behalf of the Belgian Young Rheumatologists group (BYRc) Over the past few years, important progress has been made in the field of ultrasound, allowing it to become a very powerful tool in daily rheumatology practice. Accordingly, ultrasound has now been introduced in the core curriculum of rheumatology training in most EU countries. The scope of this workshop is to improve practical skills in ultrasound imaging of the hand. SESSION 8 Chairpersons: Kristel Van Landuyt (Reumacentrum Genk) and Philip Remans (Reumacentrum Genk) The role of the microbiome in inflammatory disease Dirk Elewaut, UGent Abstract Presentations Gender differences in the disease expression and articular manifestations among patients with psoriatic arthritis - Data from the BEPAS cohort Kurt de Vlam, R. Lories, S. Steinfeld, F. Van Den Bosch, A. Nzeusseu Toukap, H. Leroi on behalf of the BEPAS study group Biomechanical stress as primary driver for inflammatory arthritis Isabelle Cambré, N. Schryvers, E. Verheugen, S. Lambrecht, P. Jacques, D. Elewaut Differences in histological score and histoclinical correlations in ACPA- versus ACPA+ rheumatoid arthritis patients Fadil Pirbuccus, C. Galant, A. Nzeusseu, F.A. Houssiau, P. Durez, B.R. Lauwerys Bone and Joint lecture Can synovial pathobiology inform diverse disease evolution and response to therapy in rheumatoid arthritis? Costantino Pitzalis, London, UK Friday, September Update in Therapeutics Pfizer Management of rheumatic conditions in 2016: Perspectives of rheumatologists, payers & patients René Westhovens, KUL Coffee Break SESSION 9 Chairpersons: Barbara Neerinckx (KUL) and Philippe Carron (UGent & AZ Alma) Thieves Market Cytomegalovirus infection and multiple venous thrombosis: A rare complication of a common infection Gauthier Molls, V. Gangji, V. Badot, M.S. Soyfoo Refractory polyarthritis in systemic light chain deposition disease Mark Walschot, E. De Langhe, P. Verschueren, D. Cassiman, T. Tousseyn, M. Delforge, B. Sprangers Case report: Heerfordt s syndrome/uveoparotid fever Matthieu Claus, I. Hoffman An unusual swelling of the lower eyelid Ine Vos, C. De Keyser, B. Babusiaux, J. Van Offel, L. De Clerck Update in Therapeutics MSD Update in Therapeutics UCB Silence and science behind chronic pain in RA and SpA Jon Lampa, Stockholm, Sweden Closure of the Congress Farewell Lunch Meeting of the BRV-ARB KBVR-SRBR Board Meeting

7 Thursday, September 29 Meeting for Health Professionals in Rheumatology - Morning Organised by the Belgian Health Professionals in Rheumatology (BHPR) vzw/asbl Chairpersons: Karlien Claes (UZ Ghent) and Seher Arat (KU Leuven) Registration* Welcome to the Health Professionals in Rheumatology Meeting Karlien Claes, Rheumatology Nurse; Rheumatology, Ghent University Hospital; Member of the Working Group Rheumatology Nurses NVKVV; Member of the BeHPR vzw/asbl Seher Arat, Rheumatology Nurse, Researcher, Skeletal Biology and Engineering Research Center, KU Leuven Viewpoint of the patients on care Nele Caeyers, ReumaNet vzw; Chair-elect Standing Committee of PARE, EULAR Update on the role of illness perceptions in rheumatic diseases Amandine Turchet, Occupational Therapist, Haute Ecole de Leonard Vinci, Brussels What s hot in Rheumatology? Part I The implementation process of the Canadian Occupational Performance Measure (COPM): Perception and experience of occupational therapists Pauline Hoelinger, Occupational Therapist, University Hospital Saint-Luc, Member of the BeHPR vzw/asbl Shared care of rheumatologist and nurse consultations in follow up of rheumatoid arthritis and spondyloarthritis outpatients with low disease activity: A monocentric, randomized controlled trial Karlien Claes, Rheumatology Nurse; Rheumatology, Ghent university hospital; Member of the Working Group Rheumatology Nurses NVKVV; Member of the BeHPR vzw/asbl Coffee Break in front of the Meeting Room Thursday, September 29 Meeting for Health Professionals in Rheumatology - Afternoon Organised by the Belgian Health Professionals in Rheumatology (BHPR) vzw/asbl Chairpersons: Karlien Claes (UZ Ghent) and Seher Arat (KU Leuven) General Assembly Belgian Health Professionals in Rheumatology vzw/asbl (welcome to all) Healthy food and lifestyle advice in clinical practice A workshop Speaker TBC What s hot in Rheumatology? Part II Do we need a patient peer mentor programme in daily practice and if so, how should this be organised? An explorative focus group study with four key stakeholders in the care of patients with early rheumatoid arthritis Kristien Van der Elst, Rheumatology Nurse, University Hospitals Leuven; Dept. of Public Health and Primary Care, Academic Center for Nursing and Midwifery, KU Leuven Coffee Break Biologicals versus biosimilars: The past, the present and the future Filip Van den Bosch, Rheumatologist, Ghent university Hospital, Ghent University Closing discussion and future congress Thijs Swinnen, Physical Therapist, University Hospitals Leuven; Chair BeHPR *Free of charge: Includes registration, coffee breaks and lunch. Pre-registration, however, is mandatory. To register, send an to thijs.swinnen@uzleuven.be Healthy lifestyle: Co-morbidities and food supplements Ruth Wittoek, Rheumatologist, MD, PhD, Ghent university hospital and Merksem Jan- Palfijn Hospital Joint session BEHPR/scientific program Patient tailored adherence interventions: From evidence to practice Fabienne Dobbels Dept. of Public Health and Primary Care, Academic Center for Nursing and Midwifery, KU Leuven Lunch Break and Networking

8 Registration Registration Fees EARLY LATE Until August 31 As of September 1 Members KBVR-SRBR 150,00 250,00 Non Members 250,00 350,00 Trainees in Rheumatology* 50,00 75,00 Other Trainees* 75,00 100,00 Researchers non-md* 50,00 75,00 Emeriti 50,00 75,00 Workshops** Free Free Health Professionals Meeting*** Free Free * Registration as a trainee or researcher non-md will only be accepted if accompanied by a copy of your student card or a certificate of your director (proof to be uploaded during the registration process). Without proof the non-member fee will be charged. ** Participation in the workshops is free of charge and is limited to 30 participants. *** Register via: thijs.swinnen@uzleuven.be The registration fee for participants includes Participation in all scientific sessions Participation in the quiz and hands-on workshops (separate registration required, limited to 30 participants) Participation in the Updates in Therapeutics organised by the Industry Congress bag with the Programme and Abstracts and congress related documents Access to the exhibition Lunches and coffee breaks How to register You can register online through the congress website Click on Registration for details and access to the online registration form. When your registration is completed successfully, you will receive a confirmation in due course. You can also print an invoice when you finalise your online registration. Hotel Accommodation A number of hotel rooms have been booked at special group rates, including breakfast and VAT. You can reserve your hotel room through the online registration form. The below rates are only valid for reservations made through Medicongress. Any requests for hotel accommodation must be accompanied by a credit card number, in order to secure the room. This credit card will not be charged by the organisers but only serves as a reservation guarantee. Room availability cannot be guaranteed after August 15. Participants will have to pay their hotel room and personal expenses at the reception of the hotel. In case of late cancellation or no show, the room will be charged on the credit card. Van der Valk Charleroi Airport Standard Single: 105,00 Standard Double: 118,50 Superior Single: 115,00 Superior Double: 128,50 City tax: 2,00/person/night Cancellation Policy Rooms can be cancelled free of charge until 4 weeks before the Congress. Rooms cancelled later will be charged at 100%. The first night of your stay will be charged by the hotel on 27 September. Changes/Name Substitutions You will receive a personal link in your final confirmation . With this link it will be possible to make changes or transfer your registration to a colleague free of charge. Cancellations Participants canceling their registration before September 1, 2016, will receive a full refund, less 50,00 administration costs. There will be no refunds for cancellations received after this date. Cancellations must be confirmed in writing to the Organising Secretariat. All refunds will be processed after the Congress

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