CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES. Transport excess tissue fluid back to blood stream

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES. Transport excess tissue fluid back to blood stream"

Transcription

1 CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES 1. Name the organs that compose the lymphatic system and give three general functions performed by this system. Control Disease Bone Marrow Thymus Transport dietary fat Lymph nodes Spleen Transport excess tissue fluid back to blood stream 2. Trace the flow of lymph from interstitial tissues to the bloodstream. Lymphatic capillaries Afferent lymphatic vessels Lymph nodes Efferent Lymphatic vessels Lymphatic trunks Collecting Duct Subclavian Veins 3. Discuss the function of anchoring filaments that surround lymphatic capillaries. Open the space between lymphatic capillary cells so leaked tissue fluid can enter. 4. Name four tissues that do not contain lymphatic capillaries. CNS Splenic pulp Bone marrow Avascular tissues 5. Give the special name for lymphatic capillaries within the wall of the small intestine. Lacteals

2 6. Distinguish between an afferent and efferent lymphatic vessel. Afferent Efferent Toward (Lymph Node) Exit (Lymphatic Trunk) 7. Explain how lymphatic vessels are similar to veins. They carry low pressure fluid against gravity. They are equipped with valves. 8. List the six primary body regions drained by lymphatic trunks. Jugular trunk Bronchomediastinal trunk Intercostal trunk Subclavian trunk Intestinal trunk Lumbar trunk 9. Name the two lymphatic collecting ducts and indicate the portion of the body that is drained by each. Right Lymphatic Duct Thoracic Duct (Left Lymphatic Duct) Drains Left and lower right (75%) of body Drains upper right 25% of body 10. Name the vein that each of the two collecting ducts deposit their lymph. Subclavian vein 11. Discuss the composition of interstitial fluid and lymph. Plasma components minus proteins

3 12. List the functions of lymph, noting its major function. Absorb and transport dietary fats Collect excess interstitial fluids and deliver back to the bloodstream Deliver foreign particles to lymph nodes for removal and destruction (phagocytosis by macrophages). 13. Explain the forces involved in the movement of lymph. It is similar to venous blood movement. It is aided by the action of skeletal muscle, respiratory movement and valves in lymphatic vessels. 14. Name the condition that occurs when lymphatic flow is obstructed. Edema_ 15. Discuss the structure, location, and major function of lymph nodes. Bean shaped. Located along lymphatic pathways. Convex side receives the afferent lymphatic vessels. The efferent vessel leaves on the concave side. Filters and remove debris from lymph for removal and destruction (phagocytosis by macrophages). 16. Discuss the structure, location, and major function of the spleen. Located behind the stomach on the left side and it filters debris and worn cells from blood. White pulp = lymphocytes Red pulp = red blood cells, lymphocytes and macrophages. 17. Distinguish between the body fluids filtered by lymph nodes and those filtered by the spleen. Lymph nodes Filter lymph Spleen Filters blood 18. Name the cell responsible for the filtering action of the lymph node and spleen. Macrophages

4 19. Discuss the structure, location, and major function of the thymus. Located within the mediastinum, soft bi-lobed and decreases in size in adults. The function is to process T-cells in immunity. 20. Name the hormone secreted by the thymus that causes maturation of lymphocytes that have migrated to other tissues. Thymosin 21. Describe what happens to the thymus as one ages. Shrinks 22. Define the term pathogen. Disease causing agent. Bacteria, viruses, protozoa, etc. 23. Distinguish between the body's two types of defense mechanisms against infections. Specific Defense Mechanisms Non-specific resistance General defenses, protect against many Immunity, very specific pathogens 24. Define the term non-specific (innate) resistance and discuss the body's seven major mechanisms. Non specific (innate) general defenses, protects against many pathogens. Skin (Mechanical Barriers) Mucous Membranes (Mechanical Barriers) Phagocytosis Inflammatory response Fever Interferons Specific resistance 25. Name the antibacterial enzyme present in tears. Lysozyme

5 26. Discuss how interferons, defensins, and collectins aid in fighting infection. Interferon Secreted by non-infected cells in response to the presence of viruses. They interfere with proliferation of viruses. Defensins destroys bacteria by punching holes in cell walls Collectins Protect by attaching themselves to a variety of microbes. Provide broad protection against them. 27. List the cardinal signs of inflammation. Redness = rubor Swelling = tumor Heat = calor Pain = dolor 28. List the steps involved in the inflammatory process. Inflammation is a tissue response to damage, injury, or infection. Blood Vessels dilate increasing capillary permeability so blood floods area. Chemicals released by damaged tissues attract various white blood cells to the site of injury. Tissue fluid leaks into area Fibroblasts arrive 29. Discuss the importance of phagocytosis, and indicate the origin of phagocytic cells. Phagocytosis special white blood cells that destroy foreign particles from tissues and body fluids. Origin Neutrophils or monocytes in the blood are called phagocytes. Those that leave the blood through diapedesis are called macrophages. 30. Define the term adaptive resistance/ immunity. Specific attack on an antigen.

6 31. Define the term antigen, and discuss how antigens cause immune responses to occur. Substance (usually a protein) that causes the formation of an antibody & reacts specifically with that antibody causing an immune response. 32. Discuss the origin and maturation of lymphocytes. Stem cells in red bone marrow give rise to undifferentiated lymphocytes that are released into the blood. Those that reach the thymus are processed into T-Cells; those that are not processed by the thymus are most-likely processed in the fetal bone marrow and are called B-Cells. The T & B cells are transported through the bloodstream and also inhabit lymphatic organs. 33. Discuss the process by which an immune response occurs, beginning with the antigen-presenting cell. Macrophages in the tissues receive the antigen first. They present the antigen to the T- cell, which then activates the B-Cell. 34. Distinguish between T cells and B cells. B-Cells T-Cells processed in the thymus processed in fetal bone marrow Function in cell mediated immunity Function in antibody-mediated immunity. 35. Distinguish between Cell-Mediated Immunity (CMI) and Antibody-Mediated (or humoral) Immunity (AMI). Antibody-Mediated Immunity (AMI) Cell Mediated Immunity (CMI) Direct attack on the antigen B-Cells provide an indirect attack on T-Cells provide cell mediated immunity. antigen. Once processed, both T-Cells and B-Cells Once activated, B-Cells proliferate into inhabit lymphatic organs. large plasma cells that produce antibodies. (Igs) that attack the antigen.

7 36. Discuss the general structure of an antibody (immunoglobulin [Ig]). Resemble a Y, with 4 amino acid chains; 2 heavy chains, and 2 light chains. 37. Name the five major classes of immunoglobulin s and list the major characteristics of each. IgG 80% Most abundant. Only antibody to cross placenta. IgA 13% Defends against bacteria and viruses. Tears, saliva, breast milk. IgM 6% 1 st antibody to be secreted after initial exposure. Located in plasma. IgD <1% Located on the surface of most B lymphocytes. IgE <.1% Involved in allergic response. Located on exposure gland secretion. 38. Name the most abundant Ig. IgG 39. Name the only Ig that can cross the placenta. IgG 40. Name the Ig produced during a primary immune response (IR). IgM 41. Name the Ig produced in abnormal amounts during allergic reactions. IgE 42. Discuss the many actions of antibodies. Attack antigens directly Direct Attachment involves agglutination, precipitation, neutralization. Activation of complement (Positive feedback mechanism) Opsonization, chemotaxis, inflammation, lysis.

8 43. Distinguish between agglutination, precipitation, neutralization, and lysis. Agglutination: Antigens clump Precipitation : Antigens become insoluble Neutralization : Antigens lose toxic properties Lysis : Cell membrane ruptures 44. Name the positive feedback mechanism that is activated by antibodies and list its effects. Complement 45. Compare and contrast a primary IR vs. a secondary IR. IgM (Primary) IgG(Secondary) Slow Huge/Quick 46. Discuss the four practical classifications of immunity. Naturally Acquired (ACTIVE) Live Pathogen Suffer disease symptoms Artificially Acquired Vaccine containing dead or weakened (ACTIVE) pathogen Possible mild symptoms or no disease symptoms Naturally Acquired IgG Antibodies that cross placenta from (PASSIVE) Artificial Acquired (PASSIVE) mom to fetus Injection of gamma globulin with ready made antibodies. No immune response, short term immunity. 47. Explain how immediate-type allergic reactions occur and proceed. Inherited Causes production of high IgE ;levels When allergens combine with IgE, this causes mast cells to burst and release histamine causing tissue damage. Symptoms: hives, hay fever, asthma, eczema, gastric disturbances, anaphylactic shock.

9 48. Name the four types of transplants performed. Isograft Autograft Allograft Xenograft 49. Discuss the major problem that occurs in autoimmune disorders, and list some possible causes of autoimmunity. Can t distinguish self from non-self. Maybe caused by previous viral infection, faulty T-Cell development, persistent fetal cells. 50. Explain the theory of microchimerism, as it relates to autoimmunity (AI). Microchimerism seen Scleroderma most likely due to persistent fetal cells. This may explain predominance of AI in females.

Lymphatic System - Structures

Lymphatic System - Structures Lymphatic System - Structures Lymphatic vessels Lymphatic tissues and organs 1 Lymphatic System - Functions Returns leaked plasma to blood vessels Cleanses lymph of bacteria & other foreign matter Provides

More information

What is the lymphatic system and what are its functions? Detail the path followed by fluid entering lymphatic capillaries. What forces cause the

What is the lymphatic system and what are its functions? Detail the path followed by fluid entering lymphatic capillaries. What forces cause the 2. 2. 2. 3. 4. 5. 6. 7. 8. 9. 10. 1 12. 13. 14. 15. What is the lymphatic system and what are its functions? Detail the path followed by fluid entering lymphatic capillaries. What forces cause the fluid

More information

Unit 9: The Lymphatic and Immune Systems NURSING PHYSIOLOGY (NRSG237)

Unit 9: The Lymphatic and Immune Systems NURSING PHYSIOLOGY (NRSG237) Unit 9: The Lymphatic and Immune Systems Dr. Moattar Raza Rizvi NURSING PHYSIOLOGY (NRSG237) Functions: Transports Excess Interstitial Fluid Back to Bloodstream Lymphatic vessels collect lymph from loose

More information

The Lymphatic System

The Lymphatic System The Lymphatic System Transports escaped fluids back to the blood Plays essential roles in body defense and resistance to disease Lymph excess tissue fluid carried by lymphatic vessels Properties of lymphatic

More information

Chapter 14: The Lymphatic System and Immunity

Chapter 14: The Lymphatic System and Immunity Chapter 14: The Lymphatic System and Immunity Major function of the Lymphatic System o Network of vessels that collect and carry excess fluid from interstitial spaces back to blood circulation o Organs

More information

The Lymphatic System and Body Defenses

The Lymphatic System and Body Defenses o The Lymphatic System and Body Defenses Lymphatic system Anatomy Non specific defenses o The Lymphatic System Consists of two semi-independent parts Lymphatic vessels Lymphoid tissues and organs Lymphatic

More information

Unit Four. Human Anatomy & Physiology

Unit Four. Human Anatomy & Physiology Human Anatomy & Physiology 16 Lymphatic System URLs http://www.howstuffworks.com/immune-system.htm http://www.thebody.com/step/immune.html http://www.emc.maricopa.edu/faculty/farabee/biobk/ BioBookIMMUN.html

More information

Chapter 22: Lymphatic System and Immunity

Chapter 22: Lymphatic System and Immunity I. Lymphatic System A. Functions of the Lymphatic System - list and describe: 1. 2. 3. B. Lymphatic Vessels 1. What are lymphatic capillaries? 2. Lymphatic capillaries differ from blood capillaries in

More information

Test 4 Immune System (Chapters 20 & 21)

Test 4 Immune System (Chapters 20 & 21) Test 4 Immune System (Chapters 20 & 21) Name: Date: 1) The is the largest lymphoid organ. 1) A. lymph node B. spleen C. thymus D. tonsil 2) Tonsils promote memory of pathogens by. 2) A. secreting antibodies

More information

Lymphatic and Immune Systems Homeostatic role of defense against pathogens, injury, diseased body cells, and toxins.

Lymphatic and Immune Systems Homeostatic role of defense against pathogens, injury, diseased body cells, and toxins. Lymphatic and Immune Systems Homeostatic role of defense against pathogens, injury, diseased body cells, and toxins Requires both lymph and immune systems to be effective Three levels of defense 1.Skin,

More information

Name (print) Name (signature) Period. (Total 30 points)

Name (print) Name (signature) Period. (Total 30 points) AP Biology Worksheet Chapter 43 The Immune System Lambdin April 4, 2011 Due Date: Thurs. April 7, 2011 You may use the following: Text Notes Power point Internet One other person in class "On my honor,

More information

ANATOMY OF THE IMMUNE SYSTEM THE IMMUNE SYSTEM. ANATOMY OF THE IMMUNE SYSTEM Thymus glandular organ near the heart where T cells learn their jobs

ANATOMY OF THE IMMUNE SYSTEM THE IMMUNE SYSTEM. ANATOMY OF THE IMMUNE SYSTEM Thymus glandular organ near the heart where T cells learn their jobs THE IMMUNE SYSTEM 1 ANATOMY OF THE IMMUNE SYSTEM 2 We all get sick sometimes...but then we get better. What happens when we get sick? Why do we get better? The immune system is localized in several parts

More information

Assignment. Write a two page essay describing the differences between specific and non- specific immunity

Assignment. Write a two page essay describing the differences between specific and non- specific immunity Assignment Write a two page essay describing the differences between specific and non- specific immunity 1 The Immune System 2 I. Immunity A. defense against invading parasites and abnormal cells B. Types:

More information

Antigens have specific regions where antibodies bind to them Antigens are usually molecules on the surface of viruses or foreign cells Antigenic

Antigens have specific regions where antibodies bind to them Antigens are usually molecules on the surface of viruses or foreign cells Antigenic Bio 100 Guide 22 Antigens have specific regions where antibodies bind to them Antigens are usually molecules on the surface of viruses or foreign cells Antigenic determinants are the specific regions on

More information

Lymph Transport and Immunity

Lymph Transport and Immunity Lymph Transport and Immunity Outline The Lymphatic System Lymph Vessels Lymphoid Organs Nonspecific Defenses Barriers Inflammatory Response Specific Defenses Antibodies T Cells Induced Immunity Active

More information

The Immune System. 2 Types of Defense Mechanisms. Lines of Defense. Line of Defense. Lines of Defense

The Immune System. 2 Types of Defense Mechanisms. Lines of Defense. Line of Defense. Lines of Defense The Immune System 2 Types of Defense Mechanisms Immune System the system that fights infection by producing cells to inactivate foreign substances to avoid infection and disease. Immunity the body s ability

More information

Immune System. Daryl Beatty Brazosport College Anatomy & Physiology II

Immune System. Daryl Beatty Brazosport College Anatomy & Physiology II Immune System Daryl Beatty Brazosport College Anatomy & Physiology II 21 The Immune System: Innate and Adaptive Body Defenses Which of the following best describes the immune system? a. the set of organs

More information

The Lymphatic System and Body Defenses The Lymphatic System Consists of two semi-independent parts Lymphatic vessels Lymphoid tissues and organs

The Lymphatic System and Body Defenses The Lymphatic System Consists of two semi-independent parts Lymphatic vessels Lymphoid tissues and organs The Lymphatic System and Body Defenses The Lymphatic System Consists of two semi-independent parts Lymphatic vessels Lymphoid tissues and organs Lymphatic system functions Transports escaped fluids back

More information

Introduction. Skin. The Immune System. Chapter 51

Introduction. Skin. The Immune System. Chapter 51 The Immune System Chapter 51 Introduction Vertebrates have three levels of defenses -1. The Integumentary System -Skin and mucous membranes provide first line of defense -2. Nonspecific (innate) Immune

More information

Lymph capillaries, Lymphatic collecting vessels, Valves, Lymph Duct, Lymph node, Vein

Lymph capillaries, Lymphatic collecting vessels, Valves, Lymph Duct, Lymph node, Vein WLHS/A&P/Oppelt Name Lymphatic System Practice 1. Figure 12-1 provides an overview of the lymphatic vessels. First color code the following structures. Color code in Figure 12-1 Heart Veins Lymphatic vessels/lymph

More information

ANIMALS FORM & FUNCTION BODY DEFENSES NONSPECIFIC DEFENSES PHYSICAL BARRIERS PHAGOCYTES. Animals Form & Function Activity #4 page 1

ANIMALS FORM & FUNCTION BODY DEFENSES NONSPECIFIC DEFENSES PHYSICAL BARRIERS PHAGOCYTES. Animals Form & Function Activity #4 page 1 AP BIOLOGY ANIMALS FORM & FUNCTION ACTIVITY #4 NAME DATE HOUR BODY DEFENSES NONSPECIFIC DEFENSES PHYSICAL BARRIERS PHAGOCYTES Animals Form & Function Activity #4 page 1 INFLAMMATORY RESPONSE ANTIMICROBIAL

More information

Immune System. Chapter 24

Immune System. Chapter 24 Immune System Chapter 24 Chapter Outline Immunology Lymphatic System Non-specific defense a. Defense at body surface b. Inflammation c. Phagocytosis macrophages, neutrophils d. Opsonins Ig and C 3 b e.

More information

11/20/2011. Outline. Immune System Function. Terminology. Two Types of Immune Defense. Innate Immunity = Non Specific

11/20/2011. Outline. Immune System Function. Terminology. Two Types of Immune Defense. Innate Immunity = Non Specific Chapter 43 Immune System Outline I. Nonspecific Defenses A. Barrier B. Protective proteins C. Phagocytes D. Natural killer cells E. Inflammatory reaction II. Specific Defenses A. B cells Antibody mediated

More information

Chapter 39 - The Body Defenses

Chapter 39 - The Body Defenses Chapter 39 - The Body Defenses Immunity - refers to the body s ability to resist or eliminate potentially harmful foreign material s or abnormal cells Mechanisms include: 1. Defense against invading pathogens

More information

Immune System A&P II

Immune System A&P II Immune System A&P II Lymphatic Outline Lymphatic System Defense Systems Innate Immune System Adaptive Defense System Immunodeficiencies Immune Responses Lymphatic System: Overview Figure 21.1a, b Lymphatic

More information

10. T and B cells are types of a. endocrine cells. c. lymphocytes. b. platelets. d. complement cells.

10. T and B cells are types of a. endocrine cells. c. lymphocytes. b. platelets. d. complement cells. Virus and Immune System Review Directions: Write your answers on a separate piece of paper. 1. Why does a cut in the skin threaten the body s nonspecific defenses against disease? a. If a cut bleeds, disease-fighting

More information

One of the more complex systems we re looking at. An immune response (a response to a pathogen) can be of two types:

One of the more complex systems we re looking at. An immune response (a response to a pathogen) can be of two types: Immune system. One of the more complex systems we re looking at. An immune response (a response to a pathogen) can be of two types: (pathogen - disease causing organism) 1) Non specific. Anything foreign

More information

Human Immunity. How our body s cells defend against microbial and viral invaders

Human Immunity. How our body s cells defend against microbial and viral invaders Human Immunity How our body s cells defend against microbial and viral invaders What is Immunity? The word immunity comes from the Latin immunus meaning free of burden. Thus; it is a body s general ability

More information

1) Siderophores are bacterial proteins that compete with animal A) Antibodies. B) Red blood cells. C) Transferrin. D) White blood cells. E) Receptors.

1) Siderophores are bacterial proteins that compete with animal A) Antibodies. B) Red blood cells. C) Transferrin. D) White blood cells. E) Receptors. Prof. Lester s BIOL 210 Practice Exam 4 (There is no answer key. Please do not email or ask me for answers.) Chapters 15, 16, 17, 19, HIV/AIDS, TB, Quorum Sensing 1) Siderophores are bacterial proteins

More information

Immune system. Nonspecific response: inflammation. Inflammation : the beginning. Nonspecific immunity vs. Adaptive immunity

Immune system. Nonspecific response: inflammation. Inflammation : the beginning. Nonspecific immunity vs. Adaptive immunity Immune system Body must resist disease in order to function Defends against pathogens, identifies and destroys abnormal cells. The primary pathogens are bacteria and viruses. Nonspecific immunity vs. Adaptive

More information

Chapter 22: The Lymphatic System and Immunity

Chapter 22: The Lymphatic System and Immunity Chapter 22: The Lymphatic System and Immunity Introduction Immune system the body s defenses against pathogens that produce disease 2 types of immunity Nonspecific immune mechanisms (Innate immunity) Provide

More information

SEER Training Modules

SEER Training Modules http://training.seer.cancer.gov/anatomy/lymphatic/ WiRED International wishes to thank the National Cancer Institute for use of this information. SEER Training Modules Introduction to the Lymphatic System

More information

The Lymphatic System and Immunity

The Lymphatic System and Immunity 14 The Lymphatic System and Immunity FOCUS: The lymphatic system includes lymph, lymphocytes, lymphatic vessels, lymph nodes, tonsils, the spleen and the thymus gland. The lymphatic system helps maintain

More information

Thibodeau: Anatomy and Physiology, 5/e. Chapter 20: Lymphatic System

Thibodeau: Anatomy and Physiology, 5/e. Chapter 20: Lymphatic System Thibodeau: Anatomy and Physiology, 5/e Chapter 20: Lymphatic System We have already established that this unit deals with transportation. Homeostasis of the internal environment and survival itself depend

More information

The Immune System: A Tutorial

The Immune System: A Tutorial The Immune System: A Tutorial Modeling and Simulation of Biological Systems 21-366B Shlomo Ta asan Images taken from http://rex.nci.nih.gov/behindthenews/uis/uisframe.htm http://copewithcytokines.de/ The

More information

Microbiology AN INTRODUCTION EIGHTH EDITION

Microbiology AN INTRODUCTION EIGHTH EDITION TORTORA FUNKE CASE Microbiology AN INTRODUCTION EIGHTH EDITION Differentiate between innate and acquired immunity. Chapter 17 Specific Defenses of the Host: The Immune Response B.E Pruitt & Jane J. Stein

More information

Chapter 22: The Lymphatic System and Immunity

Chapter 22: The Lymphatic System and Immunity Bio40C schedule Lecture: Immune system Lecture exam 2 postponed to Tu Feb 23 covers Ch 22, 26, 27 Multiple choice and short answer Study guides posted on website Extra credit total of 15 pts Work sheets

More information

CH 21 THE IMMUNE SYSTEM

CH 21 THE IMMUNE SYSTEM CH 21 THE IMMUNE SYSTEM Several lines of defense exist for the human body to help ensure maintenance of homeostasis. Some are general in action and others are extremely specific. Overall, we say that two

More information

I. Lymphatic System A. Lymphatic Vessels (Lymphatics) 1. Lymphatic Capillaries (Terminal Lymphatics) a. Absent in the following areas: 1) Avascular

I. Lymphatic System A. Lymphatic Vessels (Lymphatics) 1. Lymphatic Capillaries (Terminal Lymphatics) a. Absent in the following areas: 1) Avascular I. Lymphatic System A. Lymphatic Vessels (Lymphatics) 1. Lymphatic Capillaries (Terminal Lymphatics) a. Absent in the following areas: 1) Avascular Tissue 2) Central Nervous System 3) Bone 4) Bone Marrow

More information

Chapter 20: The Lymphatic System and Lymphoid Organs and Tissues. M.C. Shamier BSc Shenzhou University

Chapter 20: The Lymphatic System and Lymphoid Organs and Tissues. M.C. Shamier BSc Shenzhou University Chapter 20: The Lymphatic System and Lymphoid Organs and Tissues M.C. Shamier BSc Shenzhou University Subjects Lymphatic Vessels Lymphoid Cells and Tissues Lymph Nodes Other Lymphoid Organs Developmental

More information

Supplemental Material CBE Life Sciences Education. Su et al.

Supplemental Material CBE Life Sciences Education. Su et al. Supplemental Material CBE Life Sciences Education Su et al. APPENDIX Human Body's Immune System Test This test consists of 31 questions, with only 1 answer to be selected for each question. Please select

More information

The Body s Defenses CHAPTER 24

The Body s Defenses CHAPTER 24 CHAPTER 24 The Body s Defenses PowerPoint Lectures for Essential Biology, Third Edition Neil Campbell, Jane Reece, and Eric Simon Essential Biology with Physiology, Second Edition Neil Campbell, Jane Reece,

More information

Immune System Part II: The Innate Immune System

Immune System Part II: The Innate Immune System Immune System Part II: The Innate Immune System Devastation Caused by Pathogens Influenza epidemic 1918-1919 Killed 22 million people in 18 months. Three million people will die from malaria this year.

More information

specific B cells Humoral immunity lymphocytes antibodies B cells bone marrow Cell-mediated immunity: T cells antibodies proteins

specific B cells Humoral immunity lymphocytes antibodies B cells bone marrow Cell-mediated immunity: T cells antibodies proteins Adaptive Immunity Chapter 17: Adaptive (specific) Immunity Bio 139 Dr. Amy Rogers Host defenses that are specific to a particular infectious agent Can be innate or genetic for humans as a group: most microbes

More information

IMMUNOLOGY STRUCTURE AND FUNCTION OF IMMUNE SYSTEM

IMMUNOLOGY STRUCTURE AND FUNCTION OF IMMUNE SYSTEM 59 IMMUNOLOGY STRUCTURE AND FUNCTION OF IMMUNE SYSTEM 59.1 INTRODUCTION The immune system is engaged in a constant surveillance of the body for pathogens or tumors. Whether disease develops depends on

More information

AP BIOLOGY 2007 SCORING GUIDELINES (Form B)

AP BIOLOGY 2007 SCORING GUIDELINES (Form B) AP BIOLOGY 2007 SCORING GUIDELINES (Form B) Question 2 The defenses of the human body to the entry and establishment of a pathogen (disease-causing organism) can be divided into nonspecific responses and

More information

Innate Host Defenses Graphics are used with permission of Pearson Education Inc., publishing as Benjamin Cummings (http://www.aw-bc.com).

Innate Host Defenses Graphics are used with permission of Pearson Education Inc., publishing as Benjamin Cummings (http://www.aw-bc.com). Innate Host Defenses Graphics are used with permission of Pearson Education Inc., publishing as Benjamin Cummings (http://www.aw-bc.com). Page 1: Introduction Surface barriers (the skin, mucous membranes,

More information

Lecture 7 Immunology

Lecture 7 Immunology Slide 1 Lecture 7 Immunology Structure Components Leukocytes Lymphoid tissue Recognition of self Innate Immunity Physical and chemical barriers Phagocytosis Inflammation Adaptive immunity Humoral responses

More information

CHAPTER 22 LYMPHATIC SYSTEM AND IMMUNITY

CHAPTER 22 LYMPHATIC SYSTEM AND IMMUNITY CHAPTER 22 LYMPHATIC SYSTEM AND IMMUNITY CHAPTER OVERVIEW: This chapter introduces the lymphatic system including diffuse lymphatic tissues. Inflammation, non-specific immunity and specific immunity are

More information

Immune response is a response by your immune system to some type of pathogen. A pathogen is a disease causing organism.

Immune response is a response by your immune system to some type of pathogen. A pathogen is a disease causing organism. Immune system. This is one of the more complex systems we re looking at, mostly because we need to look at the cellular level to really understand what's going on. First some definitions: Immune response

More information

Lymphatic System. Chapter 20. Lymphatic System: Overview. Consists of two semi-independent parts:

Lymphatic System. Chapter 20. Lymphatic System: Overview. Consists of two semi-independent parts: Lymphatic System Chapter 20 Lymphatic System: Overview Consists of two semi-independent parts: A network of lymphatic vessels Lymphoid tissues and organs scattered throughout the body Returns interstitial

More information

Essentials of Anatomy and Physiology, 5e (Martini/Nath) Chapter 14 The Lymphoid System and Immunity. Multiple-Choice Questions

Essentials of Anatomy and Physiology, 5e (Martini/Nath) Chapter 14 The Lymphoid System and Immunity. Multiple-Choice Questions Essentials of Anatomy and Physiology, 5e (Martini/Nath) Chapter 14 The Lymphoid System and Immunity Multiple-Choice Questions 1) The lymphoid system is composed of A) lymphatic vessels. B) lymph nodes.

More information

The Adaptive Immune System

The Adaptive Immune System Chapter 17 Functional Anatomy of Prokaryotic and Eukaryotic Cells Lectures prepared by Christine L. Case The Adaptive Immune System Learning Objectives 17-1 Differentiate innate from adaptive immunity.

More information

Immunology. Lecture- 3

Immunology. Lecture- 3 Immunology Lecture- 3 Complement System complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to destroy and clear pathogens and viruses.

More information

The Lymphatic System

The Lymphatic System The Lymphatic System Lymphatic System Function Lymphatic System which consists of vessels and organs plays two vital roles in our lives: The vessels essentially maintain interstitial fluid levels by carrying

More information

The Lymphatic System. Dr. Naim Kittana, PhD

The Lymphatic System. Dr. Naim Kittana, PhD The Lymphatic System Dr. Naim Kittana, PhD 1 Disclosure The material and the illustrations are adopted from the textbook Human Anatomy and Physiology / Ninth edition/ Eliane N. Marieb 2013 Dr. Naim Kittana,

More information

Chapter 22: The Lymphatic System

Chapter 22: The Lymphatic System Slide 1 Chapter 22: The Lymphatic System Slide 2 What are the major components of the lymphatic system? Slide 3 Components of the Lymphatic System 1. Lymph: a fluid similar to plasma does not have plasma

More information

2. Surface barriers include the and of the respiratory, gastrointestinal

2. Surface barriers include the and of the respiratory, gastrointestinal The Immune System: Innate Host Defenses 1. Name the two major categories of innate (nonspecific) defenses: 2. Surface barriers include the and of the respiratory, gastrointestinal and genitourinary tracts.

More information

MICROBIOLOGY - IMMUNOLOGY MODULE Dr Ronnie Russell

MICROBIOLOGY - IMMUNOLOGY MODULE Dr Ronnie Russell The Specific/Adaptive Immune Response The Third Line of Defence Is called specific immunity The body s ability to recognize and defend itself against distinct invaders and their products Is a smart system

More information

Anatomy & Physiology Bio 2402 Lab Lecture. Instructor: Daryl Beatty Lab 4 A&P 2 Lymphatic System

Anatomy & Physiology Bio 2402 Lab Lecture. Instructor: Daryl Beatty Lab 4 A&P 2 Lymphatic System Anatomy & Physiology Bio 2402 Lab Lecture Instructor: Daryl Beatty Lab 4 A&P 2 Lymphatic System 20 The Lymphatic System Lymphatic System: Overview Consists of two semi-independent parts: A network of lymphatic

More information

22. Immune System and the Body s Defense

22. Immune System and the Body s Defense 22. Immune System and the Body s Defense I. Overview of Diseases Caused by Infectious Agents Disease can be caused by a variety of factors, some have causes within our bodies (e.g., genetic disorders and

More information

18 The Lymphatic System (Immune System) Nonspecific Resistance, Specific Immunity. Taft College Human Physiology

18 The Lymphatic System (Immune System) Nonspecific Resistance, Specific Immunity. Taft College Human Physiology 18 The Lymphatic System (Immune System) Nonspecific Resistance, Specific Immunity Taft College Human Physiology O 2 Diagram of Lymphatic and Cardiovascular Systems Lungs Heart Arteries w/ Plasma Arterioles

More information

Immune System Memory Game

Immune System Memory Game Immune System Memory Game Recommended Age: 12 years old Time: 45 minutes Everyday our bodies come in contact with millions of tiny organisms and particles that could potentially make us sick. Despite this,

More information

Figure 14.2 Overview of Innate and Adaptive Immunity

Figure 14.2 Overview of Innate and Adaptive Immunity I M M U N I T Y Innate (inborn) Immunity does not distinguish one pathogen from another Figure 14.2 Overview of Innate and Adaptive Immunity Our first line of defense includes physical and chemical barriers

More information

Types of Hypersensitivity. Type I: Allergic Reactions. more on Allergic Reactions

Types of Hypersensitivity. Type I: Allergic Reactions. more on Allergic Reactions Chapter 19: Disorders of the Immune System 1. Hypersensitivity 2. Autoimmunity 3. Transplant Rejection 1. Hypersensitivity What is Hypersensitivity? Hypersensitivity is an immunological state in which

More information

Lymphatic/Immune System Vocabulary Key

Lymphatic/Immune System Vocabulary Key Term Acquired Immunity Adenoids Antibody Antigen Axillary nodes B cell (B lymphocyte) Cervical nodes Complement system Cytokines Cytotoxic T cell Dendritic cell Helper T cell Immunity Immunoglobulins Immunotherapy

More information

Psychoneuroimmunology. Josée L. Jarry, Ph.D. Health Psychology, psy333 Department of Psychology University of Toronto September 30, 2002

Psychoneuroimmunology. Josée L. Jarry, Ph.D. Health Psychology, psy333 Department of Psychology University of Toronto September 30, 2002 Psychoneuroimmunology Josée L. Jarry, Ph.D. Health Psychology, psy333 Department of Psychology University of Toronto September 30, 2002 Psychoneuroimmunology - Definition The study of the link between

More information

37 2 Blood and the Lymphatic System Slide 1 of 34

37 2 Blood and the Lymphatic System Slide 1 of 34 1 of 34 Blood is a connective tissue that contains both dissolved substances and specialized cells. 2 of 34 The functions of blood include: collecting oxygen from the lungs, nutrients from the digestive

More information

Chapter 22a Lymphatic System

Chapter 22a Lymphatic System Chapter 22a Lymphatic System The function of the lymphatic system is to maintain blood volume by picking up fluid from the interstitial environment and returning it to circulation. This amounts to about

More information

The Cardiovascular System: Blood

The Cardiovascular System: Blood Essentials of Anatomy & Physiology, 4th Edition Martini / Bartholomew The Cardiovascular System: Blood PowerPoint Lecture Outlines prepared by Alan Magid, Duke University Slides 1 to 54 The Functions of

More information

Chapter 43: The Immune System

Chapter 43: The Immune System Name Period Our students consider this chapter to be a particularly challenging and important one. Expect to work your way slowly through the first three concepts. Take particular care with Concepts 43.2

More information

Overview. The Lymphatic System. Parts of the Lymphatic System. Organization of the Lymphatic System. The Immune System

Overview. The Lymphatic System. Parts of the Lymphatic System. Organization of the Lymphatic System. The Immune System Overview Chapter 20, 21. Lymphatic and Immune Systems Part I. Tissues and Nonspecific Immunity Lymphatic system functions Lymph vessel anatomy Lymphocytes Lymphatic tissues (nodules) Lymphatic organs (nodes,

More information

Lymphatic System: Overview

Lymphatic System: Overview Lymphatic System: Overview Consists of two semi-independent parts: A network of lymphatic vessels Lymphoid tissues and organs scattered throughout the body Returns interstitial fluid and leaked plasma

More information

Lymphatic System. 2. T lymphocytes gain immunocompetence within the: a. Bone marrow b. Thyroid c. Spleen d. Bursa of Fabricius e.

Lymphatic System. 2. T lymphocytes gain immunocompetence within the: a. Bone marrow b. Thyroid c. Spleen d. Bursa of Fabricius e. 1. All of the following organs actively FIGHT pathogens EXCEPT: a. Cervical lymph nodes b. Tonsils c. Spleen d. Thymus e. Axillary lymph nodes 2. T lymphocytes gain immunocompetence within the: a. Bone

More information

The Human Immune System

The Human Immune System The Human Immune System What is the immune system? The body s defense against disease causing organisms, malfunctioning cells, and foreign particles The First Line of Defense Skin The dead, outer layer

More information

Immunity. Humans have three types of immunity innate, adaptive, and passive: Innate Immunity

Immunity. Humans have three types of immunity innate, adaptive, and passive: Innate Immunity Immunity Humans have three types of immunity innate, adaptive, and passive: Innate Immunity Everyone is born with innate (or natural) immunity, a type of general protection. Many of the germs that affect

More information

The Lymphatic System

The Lymphatic System The Lymphatic System network of tissues, organs and vessels that help to maintain the body s fluid balance & protect it from pathogens lymphatic vessels, lymph nodes, spleen, thymus, tonsils, etc without

More information

Inflammation and Healing. Review of Normal Defenses. Review of Normal Capillary Exchange. BIO 375 Pathophysiology

Inflammation and Healing. Review of Normal Defenses. Review of Normal Capillary Exchange. BIO 375 Pathophysiology Inflammation and Healing BIO 375 Pathophysiology Review of Normal Defenses Review of Normal Capillary Exchange 1 Inflammation Inflammation is a biochemical and cellular process that occurs in vascularized

More information

The Structure and Function of the Lymphatic System

The Structure and Function of the Lymphatic System The Structure and Function of the Lymphatic System The lymphatic system runs though the body and is made up of organs and lymphatic tissue, this includes organs like the spleen and thymus and also lymphatic

More information

Immune System and Disease

Immune System and Disease Immune System and Disease Homeostasis Q: How does the body fight against invading organisms that may disrupt homeostasis? WHAT I KNOW WHAT I LEARNED 35.1 How do people catch infectious diseases? SAMPLE

More information

9/29/2014. Lymphoid Organs and Tissues. Lymphatic System. Returns fluids that leaked from blood vessels back to blood Consists of three parts

9/29/2014. Lymphoid Organs and Tissues. Lymphatic System. Returns fluids that leaked from blood vessels back to blood Consists of three parts Lymphatic System Lymphoid Organs and Tissues Returns fluids that leaked from blood back to blood Consists of three parts 1. Network of (s) 2. Lymph fluid in 3. Lymph cleanse lymph Provide structural basis

More information

The Humoral Immune system Structure and Diversity

The Humoral Immune system Structure and Diversity The Humoral Immune system Structure and Diversity Discussion: Introduction Our immune system protects our bodies from the harmful affects of a dizzying array of disease causing pathogens. Although our

More information

C20 Lymphatic System. Overview. 2013 Pearson Education, Inc.

C20 Lymphatic System. Overview. 2013 Pearson Education, Inc. C20 Lymphatic System Overview Lymphatic System Returns fluids that leaked from blood vessels back to blood Consists of four parts 1. Lymphatic capillaries 2. Network of lymphatic vessels (lymphatics) 3.

More information

CHAPTER 35 HUMAN IMMUNE SYSTEM STANDARDS:SC.912.L.14.52 & SC.912.L.14.6

CHAPTER 35 HUMAN IMMUNE SYSTEM STANDARDS:SC.912.L.14.52 & SC.912.L.14.6 CHAPTER 35 HUMAN IMMUNE SYSTEM STANDARDS:SC.912.L.14.52 & SC.912.L.14.6 SECTION 1 - Infectious Disease 1.Identify the causes of infectious disease. 2.Explain how infectious diseases are spread. Causes

More information

BLOOD GROUPS AND IMMUNOGENETICS

BLOOD GROUPS AND IMMUNOGENETICS BLOOD GROUPS AND IMMUNOGENETICS Knowledge of human blood types is necessary for successful transfusions. Recognition that blood types have relatively simple inheritance patterns led to their use in paternity

More information

Biochemistry of the immune system. Jana Novotna

Biochemistry of the immune system. Jana Novotna Biochemistry of the immune system Jana Novotna Immunity = protection The immune system integrated body system of organs, tissues, cells, and products that interact with many different pathogens. Specificity

More information

Immune system Disorders. Chapter 19

Immune system Disorders. Chapter 19 Immune system Disorders Chapter 19 I. Hypersensitivity Definition Once sensitized with an antigen (allergen) the immune system responds to a subsequent exposure by reacting with it in a way that damages

More information

Chapter Outline CHAPTER 35 LYMPH TRANSPORT AND IMMUNITY

Chapter Outline CHAPTER 35 LYMPH TRANSPORT AND IMMUNITY CHAPTER 35 LYMPH TRANSPORT AND IMMUNITY Chapter Outline 35.1 Lymphatic System A. Lymphatic System Characteristics 1. The mammalian lymphatic system consists of lymphatic vessels and lymphoid organs. 2.

More information

Lymphatic Vessels & Circulation

Lymphatic Vessels & Circulation The Lymphatic and Immunology Systems Resistance is the ability to ward off disease lack of resistance is termed susceptibility Nonspecific resistance to disease general defensive mechanisms effective on

More information

Chapter 3. Immunity and how vaccines work

Chapter 3. Immunity and how vaccines work Chapter 3 Immunity and how vaccines work 3.1 Objectives: To understand and describe the immune system and how vaccines produce immunity To understand the differences between Passive and Active immunity

More information

Bio 20 Chapter 11 Workbook Blood and the Immune System Ms. Nyboer

Bio 20 Chapter 11 Workbook Blood and the Immune System Ms. Nyboer Bio 20 Chapter 11 Workbook Blood and the Immune System Ms. Nyboer Name: Part A: Components of Blood 1. List the 3 plasma proteins and describe the function of each Albumins osmotic balance Globulins antibodies,

More information

Microbiology 532 Immunology Examination KEY October 30, 2003

Microbiology 532 Immunology Examination KEY October 30, 2003 KEY October 30, 2003 All questions have equal point value. You may keep the test questions. Multiple Choice (choose the best answer) 1. Receptors associated with innate immunity recognize microbes by detecting:

More information

Basics of Immunology

Basics of Immunology Basics of Immunology 2 Basics of Immunology What is the immune system? Biological mechanism for identifying and destroying pathogens within a larger organism. Pathogens: agents that cause disease Bacteria,

More information

Chapter 16: Innate Immunity

Chapter 16: Innate Immunity Chapter 16: Innate Immunity 1. Overview of Innate Immunity 2. Inflammation & Phagocytosis 3. Antimicrobial Substances 1. Overview of Innate Immunity The Body s Defenses The body has 2 types of defense

More information

Lymphocyte Recirculation

Lymphocyte Recirculation Chapter 5 Lymphocyte Migration and Inflammation Lymphocyte Recirculation Naïve lymphocytes enter lymph nodes from the blood circulation Lymphocytes return to blood via the thoracic duct Antigens from infected

More information

Immune and Lymphatic Systems

Immune and Lymphatic Systems 1. All of the following organs actively FIGHT pathogens EXCEPT: a. Cervical lymph nodes b. Tonsils c. Spleen d. Thymus e. Axillary lymph nodes 2. T lymphocytes gain immunocompetence within the: a. Bone

More information

Specific Defense: Adaptive Immunity

Specific Defense: Adaptive Immunity Specific Defense: Adaptive Immunity CHAPTER SUMMARY Elements of Specific Immunity (pp. 462-472) The body augments the mechanisms of nonspecific defense with another line of defense that destroys invaders

More information

Chapter 6. Fig What are the functions of blood? What is the composition of blood? Cardiovascular System: Blood

Chapter 6. Fig What are the functions of blood? What is the composition of blood? Cardiovascular System: Blood Cardiovascular System: Blood Chapter 6 6.1 Blood: An overview What are the functions of blood? Transportation: oxygen, nutrients, wastes, carbon dioxide and hormones Defense: against invasion by pathogens

More information

Core Topic 2. The immune system and how vaccines work

Core Topic 2. The immune system and how vaccines work Core Topic 2 The immune system and how vaccines work Learning outcome To be able to describe in outline the immune system and how vaccines work in individuals and populations Learning objectives Explain

More information

2) Macrophages function to engulf and present antigen to other immune cells.

2) Macrophages function to engulf and present antigen to other immune cells. Immunology The immune system has specificity and memory. It specifically recognizes different antigens and has memory for these same antigens the next time they are encountered. The Cellular Components

More information