FCT PhD Programme Medicines and Pharmaceutical Innovation (i3du)

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1 FCT PhD Programme Medicines and Pharmaceutical Innovation (i3du) Course ADVANCED DRUG DELIVERY March 14-18, 2016 Amphiteater B Lisbon, Portugal The FCT PhD Programme in Medicines and Pharmaceutical Innovation (i3du) trains students in target discovery, drug design, pre-clinical development, and drug safety, bridging the translational gap from discoveries on disease targets and mechanisms into novel diagnostic and therapeutic agents. The course on Advanced Drug Delivery is part of the PhD Programme in Medicines and Pharmaceutical Innovation (i3du), trains students in the development of advanced medicinal products, covering crucial aspects that determine the fate of drugs in the human or animal body, from their fundamentals to the advanced strategies to overcome the physiological barriers, including innovative technological and therapeutic applications. The course will be held at the Research Institute for Medicines (),, in Lisbon, March The training program is aimed at PhD students, but welcomes the participation of external academic and scientific community members. Registration is free but mandatory. 1

2 14th March 2016 Drug Delivery Fundamentals 09h30 10h20 10h40 11h00 11h50 12h10 14h50 15h10 16h00 Drug Delivery: Quo Vadis? José Morais Pharmacokinetics in advanced drug delivery Rosário Lobato Biodistribution of nanoparticulate drug delivery systems António Paulo Campus Tecnológico e Nuclear Instituto Superior Técnico, Universidade de Lisboa Nanotoxicology: implications for advanced drug delivery systems development Ana Francisca Betterncourt 2

3 15th March 2016 Overcoming Biological Barriers 10h00 10h50 11h10 12h00 12h20 14h50 Overcoming mucosal barriers for advanced protein delivery Bruno Sarmento INEB Universidade do Porto Nanoparticles in pulmonary drug delivery: characteristics, mechanisms of action, and toxicity Salette Reis Faculdade de Farmácia, Universidade do Porto Viral and non viral gene therapy approaches for neurodegenerative disease treatment Luís Almeida CNC Universidade de Coimbra 15h10 16h00 Neurodegenerative diseases Ana Paula Pêgo NanoBiomaterials for Targeted Therapies Universidade do Porto 3

4 16th March 2016 Biophysical Characterization 09h30 10h10 10h25 10h45 11h20 11h30 12h10 12h25 14h40 Assessment of the mechanisms of action of HIV fusion inhibitors and broad-spectrum antivirals Nuno Santos IMM Faculdade de Medicina, Universidade de Lisboa Biophysics and cancer Diana Gaspar IMM Faculdade de Medicina, Universidade de Lisboa High resolution imaging of biological systems: drug interaction with lipid membranes, proteins and cells Ana Viana CQB Faculdade de Ciências, Universidade de Lisboa Biophysical approaches to the study of drug-biomolecule interactions Rodrigo Almeida CQB Faculdade de Ciências, Universidade de Lisboa 14h55 Hybrid vesicles and biophysical tools to monitor intracellular trafficking of lipoplexes Fábio Fernandes CQFM-IN 4

5 Instituto Superior Técnico, Universidade de Lisboa 15h30 15h40 16h00 16h40 Calorimetry as a tool on membrane and membrane/drug interaction studies Margarida Bastos Faculdade de Ciências, Universidade do Porto 5

6 17th March 2016 Innovative Therapeutic Applications 09h30 10h10 10h40 11h00 11h50 12h10 Overcoming the skin barrier Sandra Simões PAT tools towards translational advanced drug delivery João Lopes Innovative Technological Applications 14h50 Spray-drying technology for targeted pulmonary delivery Ana Grenha CBR Universidade do Algarve 6

7 18 th March 2016 Drug Delivery Strategies 10h00 10h50 Intracellular drug delivery: Fundamentals and Strategies María Jesús Vicent Centro de Investigacioń Príncipe Felipe University of Valencia, Spain 11h10 Drug delivery strategies at mucosal level: the mucus as a barrier María José Alonso Center for Research in Molecular Medicine and Chronic Diseases University of Santiago de Compostela, Spain 12h00 Taking the most from nanotechnology-based drug delivery in anticancer therapy João Nuno Moreira CNC Faculdade de Farmácia, Universidade de Coimbra 7

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