The natural histamine blocker for fast allergy relief

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1 CHEWABLE TABLETS FOOD SUPPLEMENT The natural histamine blocker for fast allergy relief

2 ALLERGIC RHINITIS, A YEAR-ROUND CONDITION POLLEN Allergic rhinitis due to pollen from trees, grasses or weeds is also called hay fever. This condition occurs mainly in spring and summer during pollination period. Allergy against pollen is the number one allergic airway disease. DUST MITES PERENNIAL House dust mites allergy is a common cause of allergic asthma and allergic rhinitis, affecting million people globally. Dust mites excretions are common year-round (or perennial) indoor allergens. ANIMAL DANDER PERENNIAL Domestic cats and dogs are the most characterized pet allergens, although dander from a wide range of animals may cause inhalant allergic disease. Pet danders are common perennial indoor allergens. 70 s Discovery of raw quail egg benefits on patients suffering from airborne allergies by Dr Truffier, a French practitioner specialized in the allergy field. SEASONAL 80 s 2010 Historical clinical researches using quail egg preparations have shown significant improvements of allergy symptoms on both adults and children. STRAGEN has developed a proprietary manufacturing process to offer the quail egg benefits into a standardized and well-characterized tablet form complying with GMP standards. ALLERGIC RHINITIS, A LARGE MARKET OPPORTUNITY Allergic rhinitis is affecting up to 30% of worldwide adult population and as many as 40% of children. 30% USA/ CANADA 30% EUROPE 43% CHINA / HONG-KONG / TAIWAN 36% JAPAN / KOREA 38% TURKEY 45% MIDDLE EAST 54% AFRICA 45% LATIN AMERICA 45% SOUTH EAST ASIA 41% AUSTRALIA Maximum prevalence of allergic rhinitis worldwide

3 SNIZTOP, THE FAST ACTING HISTAMINE BLOCKER SniZtop proprietary formula prevents the allergens from getting into contact with the immune cells, blocking the release of inflammatory mediators such as histamine. SniZtop is the only natural histamine blocker clinically proven to relieve allergy symptoms within 15 minutes. SniZtop bioactives Based on natural ingredients, SniZtop is free from any side effects (such as drowsiness and dizziness) and suitable for both adults and children. SniZtop is efficacious all year round on a wide range of indoor and outdoor allergens. Immune cell 2014 Publication in Food Science and Nutrition of STRAGEN s randomized, double-blind, placebo-controlled study confirming statistically significant efficacy of SniZtop on the reduction of rhinitis symptoms LAUNCHES US NEW-ZEALAND EUROPE CANADA EFFICACY OF SNIZTOP ON ALLERGY SYMPTOMS RELIEF: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY SniZtop 's efficacy on the reduction of rhinitis symptoms acutely experienced by subjects upon exposure to a cocktail of common outdoor and indoor allergens has been proven in a randomized, double-blind, crossover, placebo-controlled study (N=43): Rhinitis symptoms were self-assessed by each subject through a Visual Analog Scale (VAS) confirming SniZtop 's efficacy versus placebo. The Peak Nasal Inspiratory Flow (PNIF), a recognized and objective measurement of nasal congestion, was significantly improved 15 minutes after product intake. CONSUMPTION OF SNIZTOP RESULTED IN SIGNIFICANT IMPROVEMENTS VS PLACEBO FOR THE FOLLOWING RHINITIS SYMPTOMS: ITCHY EYES WATERY EYES ITCHY NOSE NASAL OBSTRUCTION RHINORRHEA

4 COMPARISON OF ALLERGY SYMPTOM SCORES DURING THE 120-MINUTE FOLLOW-UP VS PLACEBO (N=43) SniZtop intake significantly improved subjects perceived feeling of well-being. NASAL OBSTRUCTION RHINORRHEA WATERY EYES ITCHY EYES ITCHY NOSE -24% -30% -20% -17% -18% SniZtop Placebo Statistically significant difference between groups (p<0.05) MEAN SCORES 15 MINUTES FAST ACTING PEAK NASAL INSPIRATORY FLOW (PNIF) VALUES EVOLUTION (N=43) SniZtop resulted in 18% improvement in nasal breathing evidenced by objective measurement. PNIF (ml/min) EXPOSURE TO ALLERGENS % improvement in nasal breathing 15 SNIZTOP OR PLACEBO INTAKE SniZtop Placebo TIME (MINUTES) THE FAST ACTING EFFICACY OF SNIZTOP ON A WIDE RANGE OF ALLERGENS MAKE IT AN IDEAL SOLUTION FOR YEAR-ROUND ALLERGIC CONDITIONS. SNIZTOP IS NATURAL AND FREE FROM ANY SIDE EFFECTS SUCH AS DROWSINESS AND DIZZINESS.

5 TECHNICAL INFORMATION SniZtop is available as a finished product form combined with zinc and benefits from the following EFSA claim: Supports the normal function of the immune system Actives: Patented quail egg extract & Zinc Regulatory: Food supplement Presentation: Tablets in bulk or packed in blister box Quality: Manufactured in France following GMP standards SNIZTOP IS A PATENTED HISTAMINE BLOCKER FOR FAST ALLERGY RELIEF Benichou AC et al., A proprietary blend of quail egg for the attenuation of nasal provocation with a standardized allergenic challenge: a randomized, double-blind, placebo-controlled study. Food Science & Nutrition Global Atlas of Allergic Rhinitis and Chronic Rhinosinusitis - Published by the European Academy of Allergy and Clinical Immunology (2015).

6 CLINICALLY PROVEN NO SIDE EFFECTS FAST ACTING NATURAL SEASONAL & PERENNIAL ALLERGIES SUITABLE FOR ADULTS & CHILDREN PATENTED VISTAMULTIMEDIA/GENEVA.05/16 STRAGEN is a privately owned company established since 1990 in Geneva, Switzerland, with a core business articulated around the development, registration and distribution of Rx and innovative Consumer Health products. - All product related information (including but not limited to therapeutic indications), trademarks, brand names and trade-dress provided herein are used by STRAGEN PHARMA SA mainly for B2B purposes, and are the sole property of STRAGEN or under exclusive license. - Any use of trademarks or brand names or trade-dress stated herein requires STRAGEN s prior written agreement. STRAGEN PHARMA SA Chemin du Pré-Fleuri Plan-les-Ouates/Geneva SWITZERLAND tel fax

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