The Play Again by Viscos Interview: A Deep Dive into Hyaluronic Acid (HA)
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- Osborne Reynard Russell
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1 The Play Again by Viscos Interview: A Deep Dive into Hyaluronic Acid (HA) Would it be correct to say that Play Again by Viscos not only enhances synovial viscosity, but also hydrates and promotes tissue repair? Yes. Hyaluronic acid (HA), the active ingredient in Play Again, is hydrophilic it attracts water. Play Again promotes tissue repair through improved hydration. When we are diagnosed with tissue or other joint injuries, the symptoms are typically swelling, pain and heat. When you increase the viscosity of the synovial fluid with HA, you also increase the hydration of the tissue and the joint loses that heat. How does Play Again actually break down so that it gets into the joints? Actually, Play Again does not break down at all. Play Again promotes high molecular weight transfer into the joints. The most commonplace introduction of HA into the joints is through injection. Any exogenous introduction of HA is metabolized by the body in 36 hours. When you take Play Again orally every day, that metabolism is refreshed every day and levels remain constant instead of peaking and subsiding through injection. The preventative advantage of Play Again is its constant absorption and daily replenishment of HA levels. Have there been any scientific studies done regarding HA's ability to treat inflammation? Yes a number of them. The inflammatory responses are heat, pain, soreness and redness. By taking HA daily, these symptoms have been shown to decrease. Play Again can be the most cost-effective way to address inflammatory issues. Of course, to reduce inflammation, we also use other remedies like the application of ice and the use of anti-inflammatory medication. When using Play Again to address inflammatory issues, users should take a loading dose for one to two weeks, until these issues are addressed VISCOS ( ) Page 1
2 Will HA repair cartilage? No. Cartilage does not have a blood supply. But any intervention designed to improve cartilage must travel through the synovial fluid. Poor quality HA does not carry these cartilage nutrients to the cartilage efficiently. The replenishing of synovial fluid you may see with Play Again use bolsters the fluid s ability to carry those nutrients to the cartilage. Play Again facilitates the transfer by boosting synovial fluid. Will I develop a tolerance to Play Again over time? No. HA is a naturally occurring chemical throughout every mammal s body. The normal aging process reduces the production of synovial fluid. We don t keep HA in our bodies as we age so we lose hydration. Your joints and skin lose hydration joints become stiff, skin becomes dry and wrinkles. Exogenous use of HA replenishes the synovial fluid as we age, so there is no way we can develop a tolerance to it. How long does Play Again remain in the system after I have stopped using it? Any exogenous or outside source of HA is effective for 36 hours after it is administered. The longer you stay on it, the more fully you will enjoy the benefits of Play Again. The shorter time you re on it, the shorter time the benefit lasts. If you have been taking Play Again for any length of time, you will retain the benefit for up to five days. What percentage of Play Again is expelled and how much is absorbed into the system? Typically, the higher your body weight, the higher dose is necessary for optimum absorption. Research shows that when you attach a radioactive isotope to the HA molecule, it does travel to the joints effectively. The definitive research on this topic is from the 2004 edition of the Journal of Applied Nutrition, Will the Real HA Please Stand Up? If I receive a joint injection like Synvisc or Orthovisc should I take the loading or ordinary recommended dose of Play Again? Injectable HA products give you a real spike in HA levels for 36 hours. When using Play Again in conjunction with injectables, it is best to use the loading dose for at least 10 days, and optimally for 14 days VISCOS ( ) Page 2
3 If I take Play Again, does that mean I don t need injectable hyaluronic acid? It is always best to follow your doctor s advice! If your doctor recommends that you receive a hyaluronic acid joint injection we recommend that you extend the life of that very expensive process by adding Play Again to support the continuing viscosity of the synovial fluid. If I am facing a big race or event, and want to ensure that my joints stay flexible and well-lubricated, should I change my Play Again dosage? When you are experiencing greater stress for your joints including a long plane ride when you may be immobile for a long stretch of time - then go back to the Play Again loading dose over that period of time to ensure that you take advantage of the benefits of HA. From the literature, it seems that most testing for results from hyaluronic acid come from thoroughbreds and other performance horses. Why is that? The reason for the equine studies is that thoroughbreds and performance horses sustain the highest levels of repetitive concussive stress to their joints at early ages and throughout their lives. They are a good model because they are naturally osteoarthritic due to the stresses and demands placed on them. Thoroughbreds are already galloping by the time they are 20 months old! Using the thoroughbred as the model demonstrates the process of HA loss dramatically, and how an oral HA supplement, like Play Again, can bolster that highly-stressed synovial fluid. The really good horsemen in every discipline are really most receptive to the prevention message. Joints are not perpetual motion machines. The body can only take so much stress and after that, can tolerate only so many injections. You can begin taking Play Again at a young age and by taking Plan Again preventatively, you can anticipate the loss of synovial fluid that comes through stress and concussive force VISCOS ( ) Page 3
4 Who are Play Again s top competitors in the marketplace, and how does Viscos differ from them? Play Again differs from any hyaluronic acid supplement pill or tablet for three reasons. First, pill forms of HA contained a powdered form of hyaluronic acid. Once the HA molecule is dessicated, it loses most of its effectiveness. The advantage of an HA supplement is in the liquid, longchain molecule. Second, the key to the success of Play Again is that it is absorbed in the mucosal membranes of the mouth and throat long before it ever reaches your digestive tract. Stomach acid breaks down the HA molecule so the liquid formulation has a much better chance of making it into your joints! Third, Play Again has the highest molecular weight available on the market weighing in at 2.4 million daltons. This is the weight according to the Journal of Applied Nutrition that has the best effect on joint health. Our real competition is not from other HA supplements because we are a unique product in the market. Our competition is really the non-steroidal, anti-inflammatory drugs (NSAIDs). NSAIDs include over-the-counter pain relievers, like ibuprofen, Alleve or Tylenol, and prescription pain relievers, like Celebrex. NSAIDs work effectively to reduce inflammation and joint pain. They are not, however, meant to be used on an everyday basis, as is often depicted in television commercials. The FDA has issued warnings advising consumers to be aware of the devastating side effects of these pain relievers, which include stroke, heart attack, high blood pressure, bleeding ulcers, kidney and liver failure, anemia and life-threatening skin and allergic reactions ( NSAIDs are considered safe when used as needed, never over ten (10) consecutive days without the advice of a physician. In summary, what are some of the advantages of Play Again? We assay our product for quality. No other manufacturer does this. We use a photospectrographic process to ensure the quality and molecular weight of Play Again VISCOS ( ) Page 4
5 Play Again has the highest molecular weight HA of any liquid HA product on the market. Our powdered HA competitors cannot compete. Powdered HA cannot work unless it is hydrated. No powdered product can deliver on an inflammatory response or hydrate as well as the larger molecular weight of Play Again by Viscos. What about powdered glucosamine? Glucosamine is absorbed differently by the body it must be digested unlike Play Again, that is absorbed by the oral mucosal membranes before it hits the digestive system. Glucosamine takes longer to help because it must be digested and absorbed through the bloodstream after digestion. This process takes up to 30 days. Do young people really need Play Again? Will it protect their joints? Or, is it mostly beneficial to older adults who are longer producing HA in their joints? Active young people can only benefit from a daily maintenance dose of Viscos. Forced exercise puts undue stress on joints therefore these young athletes experience acceleration of the degenerative joint process. Younger people can use Play Again to prepare for joint deterioration and to potentially reduce the need for NSAIDs or other invasive interventions in the future. Disclaimer The U.S. Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure or prevent any disease VISCOS ( ) Page 5
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