Cell and Tissue Culture Supplies: Market Research Report

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1 Cell and Tissue Culture Supplies: Market Research Report Phone: Fax:

2 Cell and Tissue Culture Supplies: Market Research Report Date: January 6, 2014 Pages: 232 Price: US$ 4, ID: CC24078D08BEN This report analyzes the worldwide markets for Cell and Tissue Culture Supplies in US$ Thousands by the following Product Segments: Media, Sera, and Reagents. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, and Latin America. Annual estimates and forecasts are provided for the period 2013 through Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 67 companies including many key and niche players such as - Affymetrix, Inc. AMRESCO, Inc. BD Biosciences Corning, Inc. EMD Millipore Table of Content I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS Study Reliability and Reporting Limitations Disclaimers Data Interpretation & Reporting Level Quantitative Techniques & Analytics Product Definitions and Scope of Study Cell/Tissue Culture Media, Sera and Reagents Media Sera Reagents II. EXECUTIVE SUMMARY 1. MARKET DYNAMICS Outlook Biopharmaceuticals & Biosimilars to Fuel Growth Select Biologic Drugs Losing Patent Protection: Regenerative Medicine Kindles Exciting Prospects Personalized Medicine Offers New Growth Avenues Industrial vs. Academic 2. TRENDS AND ISSUES Mammalian Cell Culture Media on the Growth Curve Cell and Tissue Culture Supplies: Market Research Report 2

3 3D TECHNOLOGY TO PUT A NEW SPIN ON IN VITRO CELL ANALYSES Stem Cells and Vaccines Key Drivers Increasing Applications of Adult Stem Cells to Drive Growth Growing Acceptance for Hi-Veg Culture Media Trend towards Media Optimization and Specialization Fed-Batch Cultures A Big Hit with Large-Scale Bioprocessors Trend towards Serum-Free Media Pharmacokinetics to Drive Market Growth Bioresearch and Cell Culture in Protein Based Drug Development Sluggish Fetal Bovine Serum Market Specialty Media Demand on Rise Growth of Defined Media Regulations Prompt Change in Trends Outsourcing Trend to Drive Gains Factors Impacting Growth Business Models Driving the Need for Contract Manufacturing Target Sectors for Contract Manufacturers Other Trends Underlying Threat to Cell Culture Industry 3. COMPETITIVE LANDSCAPE Table 1. Leading Players in the Global Cell Culture Supplies Market (2013): Percentage Breakdown of Value Sales for Affymetrix Inc., BD Biosciences, EMD Millipore, Life Technologies Inc., SAFC Biosciences and Thermo Fisher Scientific and Others (includes corresponding Graph/Chart) 4. END-USE ANALYSIS End-Use Applications Cell Therapy Cell Therapy Applications Key Factors Affecting the Cell Therapy Market Future Trends Related Market Sectors Progenitor Cell Therapy Stem Cell Therapy Other Related Technologies Somatic Cell Nuclear Transfer (SCNT) Tissue Engineering 5. CELL/TISSUE CULTURE: PHYSIOLOGICAL OVERVIEW Introduction History Plant Culture: The Timeline Plant Cell and Tissue Culture (PCTC) Plant Tissue Culture Techniques and Applications Cell/Tissue Culture Media, Sera and Reagents Classical Media Specialty Media Serum Fetal Bovine Serum Serum-Free Media Cell and Tissue Culture Supplies: Market Research Report 3

4 Cell Culture Reagents Role of Tissue Culture in the Growth of Cell Types Equipment Storage and Preservation Maintenance Media and Growth Requirements Methods of Tissue Culture Preparation of Media Growth and Morphology Sub Culturing Adherent Cells Thawing Frozen Cells Freezing Cells 3D CULTURE-ENABLING TECHNOLOGIES Natural Scaffold Substrates Hydrogels Inert Non-Degradable Scaffolds Biodegradable Materials Cell Culture Contamination Chemical Contamination Biological Contamination Cross Contamination by Other Cell Cultures Consequences/Problems of Contamination Controlling Cell Culture Contamination 6. PRODUCT INNOVATIONS/INTRODUCTIONS Pfanstiehl Introduces Non-Animal-Derived, cgmp- Produced Galactose for Optimizing Cell Culture Media Cayman Chemical and 3D Biomatrix Introduce Perfecta3D LDH Cytotoxicity Assay Kit Lena Biosciences Launches SeedEZ AMSBIO Introduces 384-Well 3D Cell Culture Plates Irvine Scientific Launches New Cell Therapy Products Jeevan BioSciences Launches Neuro X Tissue Culture Media Rainbow Scientific Introduces New StemCell Culture Systems BioSilta Launches EnPresso B Growth Systems EMD Millipore Introduces OsteoMAX-XF Thermo Fisher Scientific Launches HyCryo-STEM and HyClone HyCryo Cryopreservation Media Sigma Life Science Introduces Stemline Pluripotent Culture Medium Selexis Introduces BalanCD CHO SLX A Thermo Fisher Scientific Launches HyCell CHO Cell-Culture Medium PhoenixSongs Biologicals Launches Neural Cell Culture Media System Corning Launches Corning cellgro 7. RECENT INDUSTRY ACTIVITY Thermo Fisher Scientific Divests Select Biosciences Businesses to GE Healthcare Thermo Fisher Acquires Life Technologies Corporation AvantBio Inks Manufacturing Supply Agreement with US-based Company for Producing daof Cell Culture Systems Evotec Takes Over Cell Culture Service Lonza Inks Collaboration, Supply and Distribution Agreement with Sartorius Stedim Biotech Transparent and Molecular Response Laboratories Extend Original Validation Studies and Execution of Key Long Term Collaboration Agreement Merck Takes Over Biochrom Cell and Tissue Culture Supplies: Market Research Report 4

5 Merck KGaA Takes Over Beijing Skywing Technology 8. FOCUS ON SELECT PLAYERS Affymetrix, Inc. (US) AMRESCO, Inc. (US) BD Biosciences (US) Cell Culture Technologies, LLC (Switzerland) Corning, Inc. (US) EMD Millipore (US) Irvine Scientific, Inc. (US) Lonza Biologics Plc (UK) MP Biomedicals LLC (US) ORIGIO a/s (Denmark) PromoCell GmbH (Germany) Sera Laboratories International Ltd (UK) Sigma-Aldrich Corporation (US) SAFC Biosciences, Inc. (US) Thermo Fisher Scientific, Inc. (US) Vitrolife AB (Sweden) 9. GLOBAL MARKET PERSPECTIVE Table 2. World Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through 2020 (includes corresponding Graph/Chart) Table 3. World Historic Review for Cell and Tissue Culture Supplies by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2006 through 2012 (includes corresponding Graph/Chart) Table 4. World 15-Year Perspective for Cell and Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2006, 2014 & 2020 (includes corresponding Graph/Chart) Cell and Tissue Culture Supplies Market by Product Segment Table 5. World Recent Past, Current & Future Analysis for Media Cell and Tissue Culture Supplies by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 6. World Historic Review for Media Cell and Tissue Culture Supplies by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2006 through 2012 (includes corresponding Graph/Chart) Table 7. World 15-Year Perspective for Media Cell and Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2006, 2014 & 2020 (includes corresponding Cell and Tissue Culture Supplies: Market Research Report 5

6 Graph/Chart) Table 8. World Recent Past, Current & Future Analysis for Sera Cell and Tissue Culture Supplies by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 9. World Historic Review for Sera Cell and Tissue Culture Supplies by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2006 through 2012 (includes corresponding Graph/Chart) Table 10. World 15-Year Perspective for Sera Cell and Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2006, 2014 & 2020 (includes corresponding Graph/Chart) Table 11. World Recent Past, Current & Future Analysis for Reagent Cell and Tissue Culture Supplies by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 12. World Historic Review for Reagent Cell and Tissue Culture Supplies by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2006 through 2012 (includes corresponding Graph/Chart) Table 13. World 15-Year Perspective for Reagent Cell and Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America, and Rest of World Markets for Years 2006, 2014 & 2020 (includes corresponding Graph/Chart) III. MARKET 1. THE UNITED STATES A. Cell & Tissue Culture Market Market Trends Trend towards Serum-Free Media Table 14. Leading Players in the US Cell Culture Media Market (2013): Percentage Breakdown of Sales for Sigma-Aldrich, Hyclone, Lonza Biologics, and Others (includes corresponding Graph/Chart) Fetal Bovine Serum On a Decline Market for Stem Cell Research End-Use Analysis Table 15. US Market for Cell Culture Reagents (2013): Percentage Breakdown by End-Use for Academic, Industrial, and Non-Academic (includes corresponding Graph/Chart) Regulatory Controls Cell and Tissue Culture Supplies: Market Research Report 6

7 Guidelines Governing Use of Cell/Tissue Culture Reagents MSDS and Hazardous Information Toxic Substances Control Act Regulatory Environment Major FDA Regulations Strategic Corporate Developments Product Launches Key Players Table 16. The US Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 17. The US Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Table 18. The US 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 2. CANADA A. Table 19. Canadian Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 20. Canadian Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 21. Canadian 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 3. JAPAN Table 22. Japanese Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 23. Japanese Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Cell and Tissue Culture Supplies: Market Research Report 7

8 Table 24. Japanese 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 4. EUROPE A. Product Launch Strategic Corporate Development Table 25. European Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through 2020 (includes corresponding Graph/Chart) Table 26. European Historic Review for Cell and Tissue Culture Supplies by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 27. European 15-Year Perspective for Cell and Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets for Years 2006, 2014 & Table 28. European Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 29. European Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 30. European 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 4A. FRANCE Table 31. French Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 32. French Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Table 33. French 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - Cell and Tissue Culture Supplies: Market Research Report 8

9 4B. GERMANY A. Strategic Corporate Developments PromoCell GmbH A Key Player Table 34. German Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 35. German Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Table 36. German 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 4C. ITALY Table 37. Italian Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 38. Italian Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Table 39. Italian 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 4D. THE UNITED KINGDOM A. Product Launches Key Players Table 40. The UK Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 41. The UK Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Cell and Tissue Culture Supplies: Market Research Report 9

10 Table 42. The UK 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 4E. SPAIN Table 43. Spanish Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 44. Spanish Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Table 45. Spanish 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 4F. RUSSIA Table 46. Russian Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 47. Russian Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Table 48. Russian 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 4G. REST OF EUROPE A. Scenario in other European Countries Product Launch Key Players Table 49. Rest of Europe Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 50. Rest of Europe Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Cell and Tissue Culture Supplies: Market Research Report 10

11 Table 51. Rest of Europe 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 5. ASIA-PACIFIC A. Rise of Cell Culture in Asia By Region Table 52. Asia-Pacific Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Geographic Region - China, India, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 53. Asia-Pacific Historic Review for Cell and Tissue Culture Supplies by Geographic Region - China, India, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 54. Asia-Pacific 15-Year Perspective for Cell and Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for China, India, and Rest of Asia-Pacific Markets for Years 2006, 2014 & By Product Segment Table 55. Asia-Pacific Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 56. Asia-Pacific Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 57. Asia-Pacific 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 5A. CHINA A. Strategic Corporate Development Table 58. Chinese Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 59. Chinese Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Cell and Tissue Culture Supplies: Market Research Report 11

12 Table 60. Chinese 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 5B. INDIA Table 61. Indian Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 62. Indian Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, Table 63. Indian 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 5C. REST OF ASIA-PACIFIC Table 64. Rest of Asia-Pacific Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 65. Rest of Asia-Pacific Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 66. Rest of Asia-Pacific 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2006, 2014 & 6. LATIN AMERICA A. By Region Table 67. Latin American Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Geographic Region - Brazil and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 68. Latin American Historic Review for Cell and Tissue Culture Supplies by Geographic Region - Brazil and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 69. Latin American 15-Year Perspective for Cell and Tissue Culture Supplies by Geographic Region Cell and Tissue Culture Supplies: Market Research Report 12

13 - Percentage Breakdown of Dollar Sales for Brazil and Rest of Latin America Markets for Years 2006, 2014 & By Product Segment Table 70. Latin American Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 71. Latin American Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 72. Latin American 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 6A. BRAZIL Table 73. Brazilian Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Thousand for Years 2013 through Table 74. Brazilian Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 75. Brazilian 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - 6B. REST OF LATIN AMERICA Table 76. Rest of Latin American Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 77. Rest of Latin American Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 78. Rest of Latin American 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2006, 2014 & 7. REST OF WORLD Cell and Tissue Culture Supplies: Market Research Report 13

14 Table 79. Rest of World Recent Past, Current & Future Analysis for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2013 through Table 80. Rest of World Historic Review for Cell and Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years Table 81. Rest of World 15-Year Perspective for Cell and Tissue Culture Supplies by Product Segment - IV. COMPETITIVE LANDSCAPE Total Companies Profiled: 67 (including Divisions/Subsidiaries - 71) The United States (42) Canada (3) Japan (1) Europe (21) France (2) Germany (8) The United Kingdom (3) Rest of Europe (8) Asia-Pacific (Excluding Japan) (3) Middle East (1) Cell and Tissue Culture Supplies: Market Research Report 14

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