Sesiuni Educaţionale. Sesiunea I. Conf. Dr. Daniel Coriu, Prof. Dr. Hortensia Ioniţă Prof. Dr. Ljubomir Petrov, Prof. Dr. Ana Maria Vlădăreanu

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1 Miercuri 10 octombrie CEREMONIA DE DESCHIDERE Cocktail de bun venit - - Hotel Internaţional Hotel Internaţional Joi 11 octombrie SALA AUDITORIUM Sesiuni Educaţionale Sesiunea I Moderatori: Prof. Dr. Anca Roxana Lupu, Conf. Dr. Daniel Coriu Prof. Dr. Anca Lupu, Conf. Dr. Adriana Coliţă Conf. Dr. Daniel Coriu, Prof. Dr. Hortensia Ioniţă Prof. Dr. Ljubomir Petrov, Prof. Dr. Ana Maria Vlădăreanu COFFEE BREAK - VIZIONARE POSTERE Sesiunea II Moderatori: Prof. Dr. Galafteon Oltean, Prof. Dr. Ljubomir Petrov Prof. Dr. Galafteon Oltean, Conf. Dr. Anca Bojan Dr. Cristina Burcoveanu, Prof. Dr. Mihai Badea Prof. Dr. Gabriel Găman, Dr. Emilia Niculescu Mizil MASĂ DE PRÂNZ Hotel Internaţional Sesiunea III -Anatomie Patologică Moderatori: Dr. Camelia Dobrea, Conf. Dr. Sabina Zurac Dr. Adrian Pădurean - SUA, Conf. Dr. Sabina Zurac, Dr. Camelia Dobrea, Dr. Bogdan Fetica Sesiunea IV Moderatori: Conf. Dr. Andrei Cucuianu, Dr. Horia Bumbea Conf. Dr. Andrei Cucuianu, Dr. Andrei Coliţă Dr. Nicoleta Berbec, Dr. Horia Bumbea SALA COLOCVIUM Sesiune Asistente Medicale CINĂ - Hotel New Montana EXPOZITIE DE MEDICAMENTE SI APARATURA MEDICALA 1

2 Vineri 12 octombrie SALA AUDITORIUM Sesiuni Educaţionale/ Simpozioane Companii / Comunicări SRH Meet The Expert Breakfast Roche România Sesiunea I - Transplant Medular Moderatori: Prof. Dr. Margit Şerban, Prof. Dr. Dan Coliţă, Dr. Alina Tănase Prof. Dr. Reuven Or, Dr. Jacob Str ahilevitz, Dr. Smaranda Arghirescu, Dr. Erzsebet Benedek Prof. Dr. Dan Coliţă, Dr. Alina Tănase, Dr. Zsofia Varady COFFEE BREAK - VIZIONARE POSTERE Simpozioane Companii I Moderatori: Prof. Dr. Anca Roxana Lupu, Conf. Dr. Daniel Coriu Simpozion sponsorizat de Compania SANOFI Simpozion sponsorizat de Compania BRISTOL -MYERS SQUIBB Simpozion sponsorizat de Compania ANGELINI PHARMACEUTICALS MASĂ DE PRÂNZ Hotel Internaţional Simpozioane Companii II Moderatori: Prof. Dr. Gabriel G ăman, Dr. Cristina Burcoveanu Simpozion s ponsorizat de Compania MERCK SHARP & DOHME Simpozion sponsorizat de Compania SANDOZ COFFEE BREAK - VIZIONARE POSTERE Comunicări SRH - Sesiunea I Moderatori: Conf. Dr. Anca Bojan, Dr. Andrei Coliţă Dr. Andrei Coliţă, Dr. D. Jardan, Dr. Aurelia Tatic, Dr. Ioan Claudiu Cozac, Dr. Cornel Drăgan Dr. Horia Bumbea, Dr. Anca Ciobanu, Dr. Angela Dăscălescu, Dr. Anca Vasilache, Dr. Oana Stanca Sala OBSERVATOR WORKSHOP - Talasemii Grupul de lucru Bayer WORKSHOP - Hemofilii Sala SEMINAR Sala FORUM EXPOZITIE DE MEDICAMENTE SI APARATURA MEDICALA CINĂ - Hotel Internaţional 2

3 Sâmbătă 13 octombrie SALA AUDITORIUM Hematologie Clinică Meet The Expert Breakfast - NOVARTIS Simpozioane Companii III Moderatori: Prof. Dr. Anca Roxana Lupu, Prof. Dr. Hortensia Ioniţă SIMPOZION - sponsorizat de Compania NOVARTIS SIMPOZION - sponsorizat de Compania AOP ORPHAN SIMPOZION - sponsorizat de Compania JANSSEN-CILAG COFFEE BREAK - VIZIONARE POSTERE Simpozioane Companii IV Moderatori: Prof. Dr. Ana Maria Vlădăreanu, Prof. Dr. Galafteon Oltean, Prof. Dr. Mihaela Ghinea SIMPOZION - sponsorizat de Compania ROCHE ROMÂNIA SIMPOZION - sponsorizat de Compania NOVARTIS SIMPOZION - sponsorizat de Compania AMGEN MASĂPRÂNZ - HOTEL INTERNAŢIONAL Simpozioane Companii V Moderatori:. Dr., Dr. Conf Adriana Coliţă Răzvan Stoia SIMPOZION - Sponsorizat de Compania GLAXO SMITH-KLINE TEVA SIMPOZION - Sponsorizat de Compania SALA COLOCVIUM Hematologie Transfuzională COMUNICĂRI COMUNICĂRI COFFEE BREAK - VIZIONARE POSTERE Comunicări SRH - Sesiunea II Moderatori: Prof. Dr. Mihail Badea, Dr. Cătălin Dănăilă Dr. Cătălin Dănăilă, Dr. Manuela Crişan, Dr. Cerasela Jardan, Dr. Rodica Tălmaci, Dr. Trifa A.P., Dr. Trifa A.P., Dr. Dima D., Trifa A.P., Conf. Dr. Daniel Coriu CINĂ - HOTEL INTERNATIONAL EXPOZITIE DE MEDICAMENTE SI APARATURA MEDICALA Duminică 14 octombrie SESIUNE POSTERE - I. COFFEE BREAK SESIUNE POSTERE - II. ÎNCHIDEREA CONFERINŢEI 3

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5 Miercuri 10 octombrie CEREMONIA DE DESCHIDERE Cocktail de bun venit Hotel Internaţional Joi 11 octombrie Sesiuni Educaţionale Sesiunea I Moderatori: Prof. Dr. Anca Roxana Lupu, Conf. Dr. Daniel Coriu NOI PERSPECTIVE DE TRATAMENT ÎN LEUCEMIA LIMFOCITARĂCRONIC Ă(LLC) Anca Roxana Lupu Spitalul Clinic Colţea, Bucureşti FAZA BLASTICĂ A LEUCEMIEI MIELOIDE CRONICE Adriana Coli ţă, Centrul de Hematologie şi Transplant Medular, Institutul Clinic Fundeni, Bucureşti LIMFOMUL HODGKIN: TERAPIA DE PRIMA LINIE Daniel Coriu Centrul de Hematologie şi Transplant Medular, Institutul Clinic Fundeni, Universitatea de Medicina şi Farmacie Carol Davila, Bucureşti TROMBOCITOPENIA INDUSA DE HEPARINA Hortensia Ioniţă Universitatea de Medicina si Farmacie Victor Babe ş, Timişoara LIMFOAME INDUSE DE ORGANISME INFECŢIOASE. PATOGENEZA, PREZENTARE CLINICĂ ŞI TRATAMENT. Ljubomir Petrov, Tunde Torok, Laura Gabriela Urian Universitatea de Medicinăşi Farmacie Iuliu Hatieganu, Institutul Oncologic Ion Chiricu ţă Cluj Napoca. LIMFOAMELE MARGINALE: ABORDAREA ETIOPATOGENICA ŞI TERAPEUTICĂ COMPLEXĂ Ana Maria Vlădăreanu Spitalul Universitar de Urgenţă Bucureşti, Clinica de Hematologie COFFEE BREAK - VIZIONARE POSTERE Sesiunea I I Moderatori: Prof. Dr. Galafteon Oltean, Prof. Dr. Ljubomir Petrov MANIFESTĂRI HEMATOLOGICE ÎN INFECŢIA CU HIV Galafteon Oltean Clinica MedicinăInternăI, Compartiment Hematologie, UMG Tg.-Mureş 4

6 BOALA WALDENSTROM Anca Bojan Institutul Oncologic Ion Chiricuţă Cluj-Napoca COAGULAREA INTRAVASCULARĂ DISEMINATA DATE ACTUALE C. Burcoveanu, E. Hanganu, A. Dascalescu, C.Danaila 1 Instututul Regional de Oncologie Iaşi, 2 Universitatea de Medicina şi Famacie Gr.T. Popa TRANSFORMAREA DE TIP RICHTER ÎN LLC Mihai Badea UMF Craiova STUDII MORFOLOGICE, CITOENZIMATICE ŞI HISTOPATOLOGICE ÎN HAIRY CELL LEUKEMIA Gabriel Gaman UMF Craiova NEOPLAZIILE MIELOPROLIFERATIVE CRONICE PHILADELPHIA NEFGATIVE CLASICE. TRATAMENTUL SITUATIILOR SPECIALE Emilia Niculescu-Mizil Centrul de Hematologie şi Transplant Medular- Institutul Clinic Fundeni, Bucureşti MASĂ DE PRÂNZ - HOTEL INTERNAŢIONAL Sesiunea III -Anatomie Patologică Moderatori: Dr. Camelia Dobrea, Conf. Dr. Sabina Zurac RAPORTUL HEMATOPATOLOGIC Adrian M. Padurean, MD AmeriPath Milwaukee, Wisconsin, USA DIAGNOSTICUL HISTOPATOLOGIC DE MYCOSIS FUNGOIDES: STANDARDE ŞI LIMITE Sabina Zurac, Răzvan Andrei, Tiberiu Tebeică, Florica Stăniceanu Anatomie Patologică, Spitalul Clinic Colentina, UMF Carol Davila Bucureşti LIMFOAMELE B PRIMITIV CUTANATE Camelia Dobrea, Leny Caban, Iulia Ursuleac, Patricia Marcu, Adriana Coli ţă, Madalina Vasilic ă, R Stoia, D. Coriu Centrul de Hematologie şi Transplant Medular, Institutul Clinic Fundeni, Bucureşti LIMFOMUL PRIMAR MEDIASTINAL (TIMIC) CU CELULE MARI B 1 1,2 1,2 1 1 Bogdan Fetica, Patriciu Achimas-Cadariu, Cucuianu Andrei, Anca Popa, Delia Dima, 1,2 Ljubomir Petrov 1. Institutul oncologic Ion Chiricu ţă Cluj-Napoca. 2. Universitatea de medicinăşi farmacie Iuliu Haţieganu Cluj-Napoca COFFEE BREAK - VIZIONARE POSTERE 5

7 Sesiunea IV Moderatori: Conf. Dr. Andrei Cucuianu, Dr. Horia Bumbea LEUCEMII ACUTE MIELOIDĂ TRATAMENT Andrei Cucuianu Institutul Oncologic Ion Chiricuţă Cluj-Napoca Ion Chiricu ţă Cancer Institute, Hematology Department OPTIUNI TERAPEUTICE IN LIMFOAMELE NONHOGKINIENE CU CELULE T PERIFERICE Andrei Coliţă Clinica de Hematologie, Spitalul Clinic Colţea NOI STRATEGII TERAPEUTICE ÎN NEOPLASMELE MIELOPROLIFERATIVE CRONICE Ph NEGATIVE Nicoleta Berbec Clinica de Hematologie, Spitalul Clinic Colţea DIAGNOSTICUL LIMFOPROLIFERARILOR CU CELULA T ŞI NK ROLUL MAJOR AL IMUNOFENOTIPARII Horia Bumbea Spitalul Universitar de Urgen ţă, BucurestiUniversitatea de Medicina şi Farmacie Carol Davila, Bucureşti CINĂ - Hotel New Montana Vineri 12 octombrie SALA AUDITORIUM Sesiuni Educaţionale/ Simpozioane Companii / Comunicări SRH Meet The Expert Breakfast Roche România Sesiunea I - Transplant Medular Moderatori: Prof. Dr. Margit Şerban, Dr. Alina Tănase, Prof. Dr. Dan Coliţă PROPRIETĂŢILE TERAPEUTICE ALE CELULELOR STEM MEZENCHIMALE UMANE Reuven Or Director al Departamentului de Transplant Medular, Spitalul Universitar Hadassah - Ierusalim - Israel SPITALUL UNIVERSITAR HADASSAH - MANAGEMENTUL INFECŢIILOR FUNGICE INVAZIVE: O ABORDARE PRACTICA Jacob Strahilevitz Departamentul de Microbiologie Clinicăşi Boli Infectioase, Spitalul Universitar Hadassah, Ierusalim, Israel 6

8 MONITORIZAREA CHIMERISMULUI LA PACIENŢII CU TRANSPLANT MEDULAR ALLOGENEIC - EXPERIENŢA CENTRULUI TIMIŞOARA S. Arghirescu, C. Jinca, A. Bălan, A. Oprisoni, O. Ciocarlie, A. Isac, V. Ordodi, M. Baica, E. Gai, 2 1 A. Pascalau, Margit Şerban 1 - Universitatea de Medicină şi Farmacie Victor Babes Timişoara 2 Spitalul de Urgenţă Pentru Copii Louis Turcanu Timişoara 3 Spitalul Judeţean de Urgenţă Timişoara REZULTATELE TRANSPLANTULUI ALOGEN LA UN CAZ BOALĂ HODGKIN CU SCLEROZĂ NODULARĂ ÎN RECĂDERE POST TRANSPLANT AUTOLOG DUPĂUN TRATAMENT MINI BEAM URMAT DE CONDIŢIONARE STANDARD HD. Erzsébet Benedek, István Benedek, Judit Köpeczi,Enikő Kakucs,Aliz Tunyogi, Orsolya Benedek Departamentul de Transplant Medular, Spitalul Clinic Judetean de Urgenţă Tg. Mureş COMPLICAŢII PRECOCE ALE ALLOTRANSPLANTELOR DE CELULE STEM HEMATOPOIETICE HLA IDENTICE DE LA DONATORI ÎNRUDIŢI EXPERIENŢA CENTRULUI DE TRANSPLANT DIN INSTITUTUL CLINIC FUNDENI D.Coli ţă*, Zsofia Varady*, Alina Tănase*, C.Arion***, Anca Coli ţă***, Luminiţa Dumitrache *** Ligia Barbarii**, B. Iancu**, Alexandra Mărculescu*, Adriana Dumitrescu*, Anca Gheorghe*, D. Coriu* *Clinica de Hematologie şi Transplant Medular Institutul Clinic Fundeni, Bucureşti **Institutul de MedicinăLegal ă Mina Minovici, Bucureşti ***Clinica de Pediatrie - Institutul Clinic Fundeni, Bucureşti AUTOTRANSPLANTUL DE CELULE STEM HEMATOPOIETICE IN LIMFOAMELE MALIGNE EXPERIENTA CENTRULUI DE TRANSPLANT MEDULAR ICFUNDENI LA 10 ANI Alina Tănase, Zsofia Varady, Anca Coli ţă, Luminiţa Dumitrache, Oana Craciun, Carmen Călugaroiu, Alexandra Mărculescu, Adriana Dumitrescu, Constantin Arion, Dan Coli ţă, Daniel Coriu Centrul de Hematologie şi Transplant Medular, Institutul Clinic Fundeni, Bucureşti PRINCIPIILE REGIMULUI DE CONDITIONARE EXPERIENTA INSTITUTULUI CLINIC FUNDENI Zsofia Varady*, Alina Tănase*, Anca Coli ţă***, Luminiţa Dumitrache***, Ligia Barbarii**, B. Iancu **, Alexandra Mărculescu*, Adriana Dumitrescu*, Anca Gheorghe*, D. Coli ţă*, C. Arion***, D. Coriu* * Clinica de Hematologie şi Transplant Medular Institutul Clinic Fundeni ** Institutul de Medicina Legala Mina Minovici *** Clinica de Pediatrie Institutul Clinic Fundeni COFFEE BREAK - VIZIONARE POSTERE Simpozioane Companii I Moderatori: Prof. Dr. Anca Roxana Lupu, Conf. Dr. Daniel Coriu Simpozion SANOFI STRATEGII AVANSATE IN MOBILIZAREA CELULELOR STEM HEMATOPOIETICE MOZOBIL CONCEPTE AVANSATE IN CEEA CE PRIVESTE SITUAREA ACESTUIA IN STRATEGIILE CURENTE DE MOBILIZARE A CELULELOR STEM Dr. Grzegorz Basak Medical University of Warsaw - Poland 7

9 MOBILIZAREA CELULELOR STEM HEMATOPOIETICE CU MOZOBIL EXPERIENTA IC FUNDENI Dr. Alina Tănase Institutul Clinic Fundeni Simpozion BRISTOL - MYERS SQUIBB UTILITATEA CRITERIILOR MOLECULARE ÎN ALEGEREA INHIBITORILOR DE TIROZIN KINAZA ÎN LMC Dr. Simona Soverini - Italia SCHIMBAREA PRECOCE LA GENERAŢIA A DOUA DE ITK ÎN CAZ DE ESEC SAU RĂSPUNS SUBOPTIMAL LA IMATINIB Dr. Massimo Breccia - Italia Simpozion ANGELINI PHARMACEUTICALS CALITATEA VIEŢII PACIENŢILOR DE LA RECOMANDĂRILE GHIDURILOR LA IMPLEMENTAREA PRACTICA A MODELELOR TERAPEUTICE Prof. Dr. Anca Lupu Spitalul Clinic Coltea MASĂ DE PRÂNZ - Hotel Internaţional Simpozioane Companii II Moderatori: Prof. Dr. Gabriel G ăman, Dr. Cristina Burcoveanu Simpozion MERCK SHARP & DOHME Dr. Anca Coliţă - titlu rezervat Instutul Clinic Fundeni Dr.Alina Tănase - titlu rezervat Instutul Clinic Fundeni Simpozion SANDOZ DEVELOPMENT OF BIOSIMILAR MONOCLONAL ANTIBODIES Jan Visser Head Global Analyt Charact. & Bioanalytics, Sandoz Biopharmaceuticals COFFEE BREAK - VIZIONARE POSTERE 8

10 Comunicări SRH - Sesiunea I Moderatori: Conf. Dr. Anca Bojan, Dr. Andrei Coli ă IMPORTANŢA EVALUĂRII FACTORILOR DE RISC CITOGENETICI ŞI MOLECULARI ÎN TERAPIA LEUCEMIILOR ACUTE MIELOIDE Andrei Coli ţă, Carmen Şaguna, Mihaela Tevet, Nicoleta Berbec, Oana Stanca, Gabriela Barca, Silvana Angelescu, Doina Barbu, Florentina Grădinaru, Ana Maria Ivănescu, Geanina Ofiţeru, Cecilia Ghimici, Raluca Manolache, Elena Coles, Dumitru Jardan*, Cerasela Jardan*, Aura Arghir**, Daniel Coriu*, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea, * I.C. Fundeni, **Inst V Babeş TRATAMENTUL LEUCEMIILOR ACUTE UN MODEL PENTRU MEDICINA PERSONALIZATĂ ,2 1,2 1,2 D. Jardan, Rodica Tălmaci, Cerasela Jardan, Adriana Vulpe, Anca Coli ţă, C. Arion D. Coriu. 1 Universitatea de Medicina şi Farmacie Carol Davila, Bucureşti, România 2 Institututul Clinic Fundeni, Bucureşti, România IMPORTANTA EXAMENULUI CITOGENETIC ÎN MANAGEMENTUL PACIENTILOR CU SINDROM MIELODISPLAZIC. Aurelia Tatic¹, Otilia Georgescu¹, Cerasela Jardan¹, Oana Stanca², Mădalina Vasilica¹, Sorina Bădeli ţă¹, Adriana Coli ţă¹, Dan Coli ţă¹, Daniel Coriu¹, Genica Vulcan³ ¹ Centrul de Hematologie şi Transplant Medular Prof. Dr. Ştefan Berceanu, Institutul Clinic Fundeni ² Clinica de Hematologie, Spitalul Clinic Colţea ³ Hiperdia, Braşov ROLUL EXAMINARII PET/CT ÎN MANAGEMENTUL PACIENŢILOR CU LIMFOM 1 2 Cozac Ioan Claudiu, Laura Urian 1 - Centrul Pozitron Diagnosztika Oradea ( PET/CT ). 2 - IOCN Cluj ASOCIERE ÎNTRE LIMFOM HODGKIN ŞI LEUCEMIE ACUTA LIMFOBLASTICA Cornel Dragan, Mihaela Tevet, Doina Barbu, Silvana Angelescu, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea BOALA HODGKIN CA TRANSFORMARE RICHTERIANA ÎN LEUCEMIA LIMFOCITARĂ CRONIC Î PREZENTARE DE CAZ Horia Bumbea, Diana Cisleanu, Ana-Maria Vlădăreanu, Lavinia Bârsan, Daniela Vasile, 2 Camelia Dobrea 1 Spitalul Universitar de Urgen ţă, Bucureşti 2 Universitatea de Medicinăşi Farmacie Carol Davila, Bucureşti 3 Spitalul Militar Central Bucuresti ASOCIERE DE CLONE LIMFOIDE DIAGNOSTIC SI EVOLUTIE A UNOR CAZURI DE LIMFOPROLIFERARI CRONICE 2 1, 1 2, 1 Anca Ciobanu, Oana Stanca Irina Triantafyllidis, Cecilia Ghimici Anca Lupu 1UMF Carol Davila, Bucureşti, România; 2 Coltea Hospital, Bucureşti,România 9

11 MARKERI MOLECULARI ŞI IMUNOFENOTIPICI FACTORI DE PROGNOSTIC ÎN LEUCEMIA LIMFATICĂ CRONICĂ A. Dăscalescu, C. Dănăila, I. Antohe, G. Grigore, M. Zlei, C. Burcoveanu, D. Ghiorghiu, A. Gluvacov, A. Dascălu, A. Ştefan, E. Hanganu-Turtureanu 1 UMF Gr.T. Popa Iaşi, 2 Institutul Regional de Oncologie Iaşi TRATAMENTUL CU MABTHERA ÎN AFECŢIUNILE HEMATOLOGICE NEMALIGNE - EXPERIENTA CLINICII HEMATOLOGIE, I. O. CLUJ NAPOCA Anca Vasilache Institutul Oncologic Ion Chiricu ţă, Secţia Hematologie, Cluj-Napoca FACTORI DE RISC LA DEBUT ŞI PARTICULARITĂŢI ALE RASPUNSULUI LA TRATAMENT ÎN LIMFOMUL HODGKIN REFRACTAR Oana Stanca, Cecilia Ghimici, Andrei Coli ţă, Anca Ciobanu, Irina Triantafyllidis, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea Sala OBSERVATOR WORKSHOP - Talasemii Ceremonie de deschidere Asociaţia Pacienţilor de Talasemie Major ă Costin Ganescu Federaţia Internaţionalăde Talasemie Institutul Naţional de Hematologie Transfuzional ă Dr. Rusen Luminita Novartis Romania 09:30-10:00 Talasemia în Romania Dr. Florentina Vlăă d reanu 10:00-10:30 Fiziopatologia afecţiunilor cardiace Dr. Dimitrios Farmakis - Greccia Tratament şi urmări Dr. Teleianu Camelia 11:00-11:30 Pauza de cafea 11:30-12:00 Complicaţii Endocrine - Dr. Antonis Kattamis - Grecia 12:00-12:30 Tratament şi Urmări - Dr. Alice Albu Pauzăde masă Boli cronice de ficat Dr. Farrukh Shah - Marea Britanie, University College Hospital Complicaţii hepatice Dr. Claudiu Onogea Terapia chelatoare de fier Experienţa clinicii de Pediatre Fundeni Pauză de cafea 17:00-17:15 Consiliere psihosocialăşi drepturile pacienţilor Psiholog Sucea Adelina 10

12 17:15 17:45 17:45-18: Alianţa Naţionalăpentru Boli Rare Discuţii libere Cina Sala SEMINAR Grup de lucru BAYER Studiu privind manifestările clinice în hemofilie Prof. Dr. Polixenia Stancu Consideratii clinico-terapeutice ale Hemofiliei A la copiii interna i în clinica Pediatrie I SCJU TG.MURES ( în perioada ) Prof. Dr. Despina Maria Baghiu Manifestări hemoragice multiple la bolnavul hemofilic cu hepatită cronică virală C Prof. Dr. Galafteon Oltean Profilaxia secundară versus terapia "on demand" la pacien ii cu Hemofilie A forma severă trata i cu rfviii-fs Dr. Valentina Marusia Uscatescu Eficien a și siguran a tratamentului cu rfviii-fs la pacien ii cu Hemofilie A Prof Dr. Mihaela Ghinea Managementul pacien ilor cu hemofilie A Dr. Luminita Rusen Sala FORUM WORKSHOP - Hemofilii ASISTENŢA HEMOFILIEI IN ROMÂNIA. ÎNTRE REALITATE ŞI NĂZUINŢE 14,30-14,40 -Cuvânt introductiv Catherine Hudon, Daniel Andrei, Jerzy Windyga, Margit Serban 14,40-15,10 - Despre Programul Naţional de Ingrijire a Hemofiliei Catherine Hudon - WORLD FEDERATION OF HEMOPHILIA 15,10-15,25 - Privire de ansamblu asupra datelor actuale demografice ale hemofiliei în Romania. Daniel Andrei - A.R.H., Margit Serban, Emilia Ursu 15,25 15,40 - Asistenţa medicală a hemofiliei; date prezente şi speranţe de viitor. Ladislau Ritli, Hortensia Ionita, Margit Serban 15,40-16,10 - Asistenţa Hemofiliei in Polonia. Trecut, prezent şi perspective de viitor Jerzy Windyga - Polonia 11

13 16,10-16,30 - Discuţii 16,30-16,40 - Pauză de cafea 16,40-16,55 - Centrele de terapie comprehensivă a hemofiliei o necesitate imperioasă pentru practica clinică. Hortensia Ioniţă, Ioana Ioniţă, Liviu Chevereşan 16,55-17,05 - Proiectul SCREENGEN dedicat diagnosticului biomolecular în hemofilie. Realizări şi perspective. - Proiect euro-regional HuRo de cooperare transfrontalieră. Margit Şerban, Valentin Ordodi, Florina Boldeanu, Ioana Ciohat, Cristian Jinca, Emilia Ursu 17,05-17,20 - Importanţa tratamentului multidisciplinar la un pacient cu hemofilie A, formă severă. Amalia Matei, Sorina Badelita, Manuela Crişan,Valentina Uscatescu, Daniel Coriu 17,20-17,35 - Chirurgia osteo-articulară la bolnavii cu hemofilie. Experienţa pe 100 de cazuri operate. Dan Poenaru, Margit Şerban, Jenel Pătraşcu, Bogdan Andor 17,35-17,45 - Kineto-fizioterapia în recuperarea fizică a bolnavului cu hemofilie Alina Lăcătuşu, Florica Ghilezan, Margit Şerban 17, Discuţii 18, Închiderea Simpozionului CINĂ - Catherine Hudon, D. Andrei, Jerzy Windyga, Margit Şerban Hotel Internaţional Sâmbătă 13 octombrie Sala AUDITORIUM - Hematologie Clinică Meet The Expert Breakfast - NOVARTIS Moderator: Prof. Dr. Richard Clark, University of Liverpool, UK GOALS OF CML THERAPY Prof. Dr. Nicholas Cross Wessex Regional Genetics Laboratory, University of Southampton, Salisbury, UK Prof. Dr. Martin Muller, MD University of Mannheim, Germany 12

14 Simpozioane Companii III Moderator: Prof.Dr. Anca Lupu, Prof. Dr. Hortensia Ioniţă Simpozion NOVARTIS CURRENT LANDSCAPE OF CML TREATMENT Prof. Dr. Richard Clark University of Liverpool, UK Prof.Dr. Hortensia Ioniţă, Spitalul Municipal Timişoara CONVENTIONAL MANAGEMENT OF MYELOFIBROSIS Conf. Andrei Cucuianu Institutul Oncologic Cluj I.Chiricu ţă Simpozion AOP ORPHAN Pharmaceuticals AG NOVEL TREATMENT APPROACHES OF MYELOPROLIFERATIVE NEOPLASMS Prof. H. Gisslinger MD, Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna, Austria: EFICIENTA TERAPIEI CU THROMBOREDUCTIN IN SINDROAMELE MIELOPROLIFERATIVE Dr. Emilia Niculescu Mizil Institutul Clinic Fundeni, Centrul de Hematologie şi Transplant Medular EFICIENTA THROMBOREDUCTIN IN CONTROLUL EVENIMENTELOR TROMBOTICE SI HEMORAGICE DIN PV JAK2+: PREZENTARE DE CAZ Dr. Manuela Crişan Institutul Clinic Fundeni, Centrul de Hematologie şi Transplant Medular Simpozion JANSSEN-CILAG STRATEGII TERAPEUTICE ACTUALE ÎN MIELOMUL MULTIPLU TRECUT, PREZENT ŞI VIITOR ÎN MIELOMUL MULTIPLU NON-TRANSPLANT Dr. Maria Victoria Mateos - Spania OPTIMIZAREA TRATAMENTULUI IN MIELOMUL MULTIPLU Conf. Dr. Daniel Coriu Institutul Clinic Fundeni, Centrul de Hematologie şi Transplant Medular COFFEE BREAK - VIZIONARE POSTERE 13

15 Simpozioane Companii IV Moderatori : Prof. Dr. Oltean Galafteon, Prof. Dr. Ana Maria Vlădăreanu Prof. Dr. Mihaela Ghinea Simpozion ROCHE ROMÂNIA PERSPECTIVE PE TERMEN LUNG ÎN TRATAMENTUL MALIGNITATILOR B HEMATOLOGICE STRATEGII ŞTIINŢIFICE DE TRATAMENT ÎN LIMFOMUL FOLICULAR Prof. Dr. Anca Roxana Lupu Spitalul Clinic Colţea IMPORTANŢA TRATAMENTULUI DE PRIMA LINIE ÎN LLC Prof. Dr. Ioniţă Hortensia Spitalul Municipal Timişoara TRATAMENTUL DE ÎNTREŢINERE CU MABTHERA TRANSFORMAREA DATELOR CLINICE ÎN PRACTICA CURENTĂ Dr. Mariana Vasilică Institutul Clinic Fundeni REZULTATE PE TERMEN LUNG ÎN LIMFOMUL DIFUZ CU CELULA MARE B Conf. Dr. Cucuianu Andrei Institutul Oncologic Cluj I.Chiricu ţă Simpozion NOVARTIS PROVOCARI IN GESTIONAREA CLINICA A SMD Prof. Theo De Witte, MD Nijmegen, The Netherlands Simpozion AMGEN PRIMARY PROPHYLAXIS OF FEBRILE NEUTROPENIA IN NHL Prof. Dr. Ruth Pettengell - U.K. AGONIŞTI TPO ÎN PURPURA TROMBO CITOPENICĂ IMUNĂ Prof. Anca Roxana Lupu Spitalul Clinic Colţea EPOETINELE ÎN ANEMIA INDUSĂ DE CHIMIOTERAPIE Conf. Dr. Andrei Cucuianu Institutul Oncologic Cluj I.Chiricu ţă 14

16 MASĂ PRÂNZ - HOTEL INTERNAŢIONAL Simpozioane Companii V Moderator i : Conf.Dr.Adriana Coli ă, Dr. Razvan Stoia Simpozion GLAXO SMITH-KLINE MODIFICĂRI ŞI PERSPECTIVE ÎN MANAGEMENTUL TROMBOCITOPENIEI IMUNE CRONICE ASPECTE GENERALE ÎN TROMBOCITOPENIA IMUNĂ CRONICĂ: BIOLOGIE ŞI OPŢIUNI TERAPEUTICE Dr. Razvan Stoia Institutul Clinic Fundeni DISEASE MANAGEMENT OF citp IN ADULT: LONG TERM EXPERIENCE WITH TPO-R AGONISTS Prof Dr Adrian Newland - Marea Britanie Simpozion TEVA OPTIUNI TERAPEUTICE ÎN INFECŢIILE FUNGICE SISTEMICE Dr. Alina Tănase Institutul Clinic Fundeni COFFEE BREAK - VIZIONARE POSTERE Comunicări SRH - Sesiunea II Moderatori: Prof. Dr. Mihail Badea, Dr. Cătălin Dănăilă 10 ANI DE TRATAMENT CU IMATINIB - EVALUAREA FACTORILOR PROGNOSTICI AI RASPUNSULUI TERAPEUTIC C. Dănăila, A. Dăscalescu, G. Dorohoi, D. Ghiorghiu, A. Gluvacov, I. Antohe, G. Bujorean, D. Jitaru, I. Ivanov, C. Burcoveanu C. Hanganu 1 UMF Gr.T. Popa Iasi, 2 Institutul Regional de Oncologie Iasi LIMFOCITOZA APARUTA ÎN TIMPUL TRATAMENTULUI CU TKI DE LINIA I ŞI II LA PACIENŢII CU LMC-STUDIU RETROSPECTIV A 3 CAZURI 1, Manuela Crişan, Sorina Bădeli ţă, Emilia Niculescu Mizil, Adriana Coli ţă, Adriana Dumitrescu, 1, ,2 1,2 1,2 Cerasela Jardan, Amalia Martin, Inga Botnariuc, Denisa Bratu, Rodica Tălmaci, Daniel Coriu 1 Facultatea de Medicina şi Farmacie Carol Davila, Bucureşti, România 2 Institutul Clinic Fundeni, Bucuresti, România 15

17 PREZENTA ANOMALIILOR CITOGENETICE ADITIONALE REPREZINTA UN MARKER IMPORTANT PENTRU IDENTIFICAREA REZISTENTEI SI A PROGRESIEI BOLII IN LMC ,2 1,2 Jardan Cerasela., Jardan D., Colita Anca, Coriu D. 1- UMF Carol Davila 2- Institutul Clinic Fundeni RĂSPUNSUL MOLECULAR AL PACIENŢILOR CU LEUCEMIA MIELOIDĂ CRONICĂ TRATA ŢI CU IMATINIB ÎN FUNCŢIE DE TIPUL DE TRANSCRIPT BCR-ABL Tălmaci R., Vulpe A., Jardan D., Coriu D. Centrul de Hematologie şi Transplant Medular, Institutul Clinic Fundeni HAPLOTIPUL JAK2 46/1 CORELAŢII CU STATUSUL JAK2 V617F, CARACTERISTICILE HEMATOLOGICE ŞI EVENIMENTELE TROMBOTICE LA 172 PACIENŢI CU NEOPLASME MYELOPROLIFERATIVE Trifa A.P., Cucuianu A., Popp R.A., Urian L., Dima D., Petrov L., Militaru M., Pop I.V. 1 Departmentul de GeneticăMedical ă, UMF Iuliu Hatieganu, Cluj-Napoca 2 Institutul Oncologic Ion Chiricu ţă, Sectia Hematologie, Cluj-Napoca LIPSA CORELAŢIEI ÎNTRE POLIMORFISMUL STAT5B RS (C>T) ŞI NEOPLASMELE MIELOPROLIFERATIVE Trifa A.P., Cucuianu A., Popp R.A., Coadă C. A., Costache R.M., Sarca A.D., Farcaş M., Militaru M., 1 Pop I.V. 1 Departmentul de GeneticăMedical ă, UMF Iuliu Haţieganu, Cluj-Napoca 2 Institutul Oncologic Ion Chiricu ţă, Secţia Hematologie, Cluj-Napoca URMARIREA SISTEMATICĂCLINICA, CITOGENETICĂ ŞI MOLECULARĂA PACIENŢILOR CU LMC TRATA ŢI CU TKI. IMPACTUL ASUPRA TRATAMENTULUI. EXPERIENŢ A I. O. C. N.-HEMA Dima D., Băă l cescu O., Trifa A., Cucuianu A., Leluţiu L., Patiu M., Petrov L. 1. Institutul Oncologic Ion Chiricu ţă Secţia Hematologie, Cluj-Napoca 2. Institutul Oncologic Ion Chiricu ţă, Laborator Genomică Funcţionala 3. Institutul Oncologic Ion Chiricu ţă, Laborator Citogenetică 4. Universitatea de Medicinăşi Farmacie Iuliu Haţieganu Cluj-Napoca, Departamentul GeneticăMedicală STATUSUL BRAF V600E ÎNTR-UN LOT DE 406 PACIENŢI CU HEMOPATII MALIGNE Trifa A.P., Cucuianu A., Popp R.A., Urian L., Dima D., Bojan A., Coadă C. A., Costache R.M., Sarca A.D., Farcaş M., Militaru M., Pop I.V. 1 Departmentul de GeneticăMedical ă, UMF Iuliu Haţieganu, Cluj-Napoca 2 Institutul Oncologic Ion Chiricu ţă, Secţia Hematologie, Cluj-Napoca UN NOU TIP DE TRANSTHYRETINA MUTANTA (GLU 54 GLN) IDENTIFICAT LA PACIENTI DIN ROMANIA CU AMILOIDOZA EREDITARA D. Coriu 1, C. Ailenei, D. Jardan. R. Tălmaci, S. Badeli ţă, C. Dobrea, D.Kestler, & A. Solomon 1 University of Medicine "Carol Davila", Bucharest, Romania 2 University of Tennessee Graduate School of Medicine, Knoxville, TN, USA CINĂ - HOTEL INTERNATIONAL 16

18 SALA COLOCVIUM Hematologie Transfuzională CONSIDERAŢII PRIVIND MANAGEMENTUL DONATORULUI DE SANGE * A.M. Dobrotă, R.C. Dobrotă** * Centrul Regional de Transfuzii Sanguine Constanţa ** Spitalul I. Cantacuzino, Bucureţti CONSULTATIA MEDICALA ROL PREDOMINANT ÎN CRESTEREA SECURITAŢII TRANSFUZIONALE F. Neagu, M. Popa, I. Cristea, A. Cârstea, C. Ruxandu, M. Cazacu Centrul de Transfuzie Sanguinăal Municipiului Bucureşti CENTRUL MOBIL DE RECOLTARE DE SÂNGE TOTAL TREI ANI DE EXPERIENŢĂ F. Neagu, D. Gosa, M. Popa Centrul de Transfuzie Sanguinăal Municipiului Bucureşti RODUCTIVITATEA METATREBUINTELOR ŞI SENTIMENTUL DE PRESTIGIU LA DONATORUL DE SÂNGE A. Bugner, V. Irimia Institutul Naţional de Hematologie Transfuzională Bucureşti INFLUENŢA DONĂRILOR FRECVENTE PRIN AFEREZĂ ASUPRA PARAMETRILOR HEMATOLOGICI AI DONATORILOR E. Negoiţă*, R. Negoiţă*, A. Olteanu*, I.Răchită*, R. Caracaş** Centrul de Transfuzie Sanguină al Municipiului Bucureşti*, Institutul Na ional de Hematologie Transfuzională** ACTIVITATEA LABORATORULUI NATIONAL HLA DIN BUCURESTI PENTRU REGISTRUL NATIONAL AL DONATORILOR CELULE STEM HEMATOPOIETICE Irina Monica Dutescu*, Ruxandra Caisan*, Lorena Ulea*, Alina Bardan*, Luis Popa** *Laborator Naţional HLA, Institutul Naţional de Hematologie Transfuzional ă, Bucureşti **Departamentul de Biologie Molecular ă, Muzeul Naţional de Istorie Naturală GrigoreAntipa, Bucureşti PROCEDURI OPERATORII STANDARD IMUNOHEMATOLOGICE PENTRU INVESTIGAREA CAZURILOR DE ANEMIE HEMOLITICĂAUTOIMUNO ŞI PENTRU SELECŢIA DE SÂNGE PENTRU TRANSFUZIE S. Sirian Bucureşti ALLOIMUNIZAREA ANTIERITROCITARA LA PACIENTII POLITRANSFUZATI CU β TALASEMIE MAJORA AFLATI IN EVIDENTA INHT L. Niţu, F. Vlădăreanu, S. Sirian, D. Voicu, C. Calotă Institutul Naţional de Hematologie Transfuzională Bucureşti EVOLUTIE SI PROGNOSTIC ÎN β TALASEMIE MAJORA IN ROMANIA F. Vladareanu, D. Voicu, L. Nitu 17

19 Institutul Naţional de Hematologie TransfuzionalăBucureşti CERCETAREA VARIANTELOR DE D PARŢIAL LA CTS BRAŞOV CU AJUTORUL CARTELELOR ID-PARTIAL RHD-TYPING SET C.Roşu, E.Savuly, M.Stoian, A.Voinea Centrul de Transfuzie Sanguină Braşov INVESTIGAREA IMUNOLOGICĂ A UNEI DISCREPANŢE DE GRUP SANGUIN S. Bran, I. Ştefan Centrul Regional de Transfuzie Sanguină Craiova, Craiova, România STUDIU ASUPRA DIFERITELOR VARIANTE DE Rh ÎN POPULATZIA DE DONATORI DIN MUNICIPIULBUCUREŞTI * ** A. Zăgrean, S. Sirian, I. Duţescu*** Centrul de Transfuzie Sanguina al Municipiului Bucuresti, Bucureşti **, Institutul National de Hematologie Transfuzională. HEPATITELE VIRALE ŞI AVATARURILE DIAGNOSTICULUI SEROLOGIC G. Hanganu, M. Catana, D. Gheorghe Centrul de Transfuzie SanguinăPloieşti TENDINŢE ALE RISCULUI REZIDUAL DE TRANSMITERE PRIN TRANSFUZIE A HIV-1 DUPA ANUL 2000 A. Necula, M. Pecec Institutul Naţional de Hematologie Transfuzional ă, Bucureşti, România, Lab. Central de Referinţă Virusurile Transmise prin Sânge pentru AVANTAJELE ŞI DEZAVANTAJELE FOLOSIRII ANALIZOARELOR AUTOMATE ÎN TESTAREA BOLILOR TRANSMISIBILE PRIN SANGE M. Hoinarescu, I. Răchită Centrul de Transfuzie Sanguinăal Municipiului Bucureşti CINETICA ENZIMELOR ERITROCITARE PE PERIOADA DE STOCAJ M. Dobreanu, O. Coban Institutul National de Hematologie TransfuzionalăBucureşti DETERMINAREA HEMOGLOBINEI PRIN METODA NONINVAZIV Ă PULS-OXIMETRIA A. Olteanu*, D. Vuculescu*, M. Dobreanu** *Centrul de Transfuzie al Municipiului Bucuresti, ** Institutul National de Hematologie Transfuzionala CONTROLUL DE CALITATE AL CONCENTRATELOR TROMBOCITARE ÎNTRE CERINTE LEGISLATIVE ŞI DIFICULTATI DE IMPLEMENTARE A.M. Dobrota Centrul Regional de Transfuzie SanguinăConstanţa CONTROL BACTERIOLOGIC ÎNTRE DEZIDERAT ŞI UTIL L. Florea*, V. Nistor**, A. Voinea* C.T.S. Braşov*, C.T.S. Bârlad** HEMOVIGILENTA - DE LA LEGE LA PRACTICA G. HANGANU, M. CATANA, D. GHEORGHE 18

20 Centrul de Transfuzie SanguinăPLOIEŞTI MANAGEMENTUL ACCIDENTELOR PRIN EXPUNERE LA SANGE LA PERSONALUL DIN CENTRUL DE TRANSFUZIE BRAŞOV A. Munteanu Centrul de Transfuzie SanguinăBraşov 19

21 Duminică 14 octombrie SESIUNE POSTERE SEMNIFICAŢIA CLINICĂA MUTAŢIEI GENEI JAK2-V617F LA PACIENŢI CU NEOPLASME MIELOPROLIFERATIVE ŞI EVALUAREA ACESTEIA CA FACTOR DE RISC PENTRU APARIŢIA COMPLICAŢIILOR HEMORAGICE. Mihaela Tevet, Anca Lupu, Carmen Şaguna, Andrei Coli ţă, Raluca Manolache Clinica de Hematologie, Spitalul Clinic Colţea ROLUL MUTATIEI GENEI JAK2-V617F ÎN TRANSFORMAREA BLASTICĂA NEOPLASMELOR MIELOPROLIFERATIVE Mihaela Tevet, Anca Lupu, Carmen Şaguna, Andrei Coli ţă, Raluca Manolache Clinica de Hematologie, Spitalul Clinic Colţea SARCOMUL MIELOID ASPECTE DE DIAGNOSTIC. EXPERIENŢA CLINICII HEMATOLOGIE COLŢEA. Silvana Angelescu, Doina Barbu, Florentina Grădinaru, Nicoleta Berbec, Andrei Coli ţă, Gabriela Barca, Oana Stanca, Cecilia Ghimici, Anca Ciobanu, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea FACTORI DE PROGNOSTIC ÎN LIMFOAMELE INDOLENTE IMPLICAŢII TERAPEUTICE Anca Ciobanu, Oana Stanca Irina Triantafyllidis, Cecilia Ghimici Anca Lupu 1UMF Carol Davila, Bucureşti, Romania; 2Coltea Hospital, Bucuresti,Romania 2 1, 1 2, 1 DIFICULTA ŢI DE DIAGNOSTIC ŞI MANAGEMENT AL TERAPIEI ÎN SINDROMUL EVANS. Cristina Negotei, Nicoleta Berbec, Mihaela Lebedenco, Elena Coles, Anca Lupu Clinica de Hematologie, Spitalul Clinic Coltea PARTICULARITĂŞI EVOLUTIVE ÎN LEUCEMIA ACUTĂ MIELOBLASTIC Ă (M4) PREZENTARE DE CAZ. Mihaela Lebedenco, Nicoleta Berbec, Cristina Negotei, Elena Coles, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea LIMFOM COMPOZIT CU DETERMINARE COLONICĂŞI ASOCIERE CU DUBLĂINFECŢIE VIRALĂHEPATITICĂ Ana Maria Ivănescu, Andrei Coli ţă, Geanina Ofiţeru, Cecilia Ghimici, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea ROLUL IMUNOFENOTIPARII ÎN ELUCIDAREA DIAGNOSTICULUI NEOPLAZIILOR HEMATOLOGICE ASOCIATE. Carmen Şaguna, Raluca Manolache, Doina Barbu, Mihaela Tevet, Silvana Angelescu, Cornel Dragan, Andrei Coli ţă, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea 20

22 REZULTATELE TRATAMENTULUI CU CHELATORI DE FIER ÎN SINDROMUL MIELODISPLAZIC- PREZENTARE DE CAZ. Mihaela Lebedenco, Nicoleta Berbec, Elena Coles, Diana Măndescu, Cristina Negotei, Anca Ciobanu, Oana Stanca, Irina Triantafillydis, Andrei Coli ţă, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea EVOLUTIA ŞI PROGNOSTICUL LEUCEMIEI GRANULOCITARE CRONICE LA COPII (0-3 ANI). Gabriela Iliescu (1), Daniela Vişan (2), Gabriela Tene (1), Adriana Bold (3) 1 Spitalul Clinic Judeţean de UrgenţăCraiova 2 Spitalul Municipal Calafat 3 Universitatea de Medicinăşi Farmacie Craiova INCIDENŢA EVENIMENTELOR TROMBOHEMORAGICE ÎN TROMBOCITEMIA ESENŢIALǍ. ROLUL TRATAMENTULUI CU ANAGRELIDǍ 1, Rodica Mihaescu-, Adriana Stoian-, Andreea Dan-, Roxana Buzas-, Cristina Gug- 1. OncoMed Timisoara 2. UMF "V.BABES" Timişoara IMPLICAŢIILE PSIHO-SOCIALE ALE DIAGNOSTICULUI DE TROMBOFILIE EREDITARǍ Rodica Mihăescu - 1,2, Adriana Stoian- 1, Andreea Dan- 1, Roxana Buzas- 2, Cristina Gug OncoMed Timişoara 2- UMF "V.BABEŞ" Timişoara REZULTATELE TRATAMENTULUI LEUCEMIEI ACUTE A VARSTNICULUI. EXPERIENŢA UNUI SINGUR CENTRU Hortensia Ioni ţă, Ioana Ionita, Liviu Cheveresan, Maria Cheveresan, Claudiu Ionita, Dacian Oros, Mihai Ionita Universitatea de Medicina si Farmacie Victor Babe ş, Timişoara EVALUAREA RĂSPUNSULUI LA TRATAMENT A PACIENŢILOR CU MIELOM MULTIPLU RECAZUT ŞI REFRACTAR Ioana Ioni ţă, Liviu Chevereşan, Maria Chevereşan, Claudiu Ioni ţă, Maria Iordache, Mihai Ioni ţă, Dacian Oros, Despina Calamar-Popovici, Hortensia Ioniţă Universitatea de Medicinăşi Farmacie Victor Babe ş, Timişoara COMPLICAŢII TROMBOTICE ÎN BOLILE MIELOPROLIFERATIVE CRONICE Mihai Ioni ţă, Ioana Ioni ţă, Liviu Chevereşan, Claudiu Ioni ţă, Despina Calamar-Popovici, Hortensia Ioniţă Universitatea de Medicina şi Farmacie Victor Babe ş, Timişoara PURPURA TROMBOCITOPENICA IMUNA. ANALIZA RETROSPECTIVĂ A REZULTATELOR TERAPEUTICE ALE ULTIMILOR 15 ANI. Claudiu Ionita, Ioana Ionita, Liviu Cheveresan, Dacian Oros, Hortensia Ionita Universitatea de Medicina şi Farmacie Victor Babes, Timişoara MOMENTUL ALLOTRANSPLANTULUI DE CELULE STEM ÎN LEUCEMIA ACUTA HIGH RISK- PREZENTARE DE CAZ Georgescu D., Balea M., Patrinoiu O., Gogulescu R., Arghir A., Constantinescu A. Secţia de Hematologie - Spitalul Clinic Colentina, Bucureşti EVOLUŢIE POSTSPLENECTOMIE ÎNTR-UN CAZ DE SMD HIPOPLAZIC- PREZENTARE DE CAZ Georgescu D., Balea M., Dr. Patrinoiu O., Gogulescu R., Bumbea H., Constantinescu A. Secţia de Hematologie - Spitalul Clinic Colentina, Bucureşti 21

23 REMISIUNE MOLECULARĂMAJORĂLA 6 LUNI DE LA INIŢIEREA TERAPIEI CU IMATINIB ÎNTR-UN CAZ DE LMC FAZĂBLASTICĂLA DEBUT- CASE REPORT Patrinoiu O., Georgescu D, Balea M, Gogulescu R, Jardan C, Constantinescu A Secţia de Hematologie - Spitalul Clinic Colentina, Bucureşti PATTERNUL RECĂDERII DE BOALĂDUPĂTERAPIA CU BORTEZOMIB ÎN MIELOMUL MULTIPLU IGA Balea M, Constantinescu A, Patrinoiu O., Georgescu D, Gogulescu R Secţia de Hematologie - Spitalul Clinic Colentina, Bucureşti ZAP-70 FACTOR DE PROGNOSTIC ÎN LEUCEMIA LIMFATICĂCRONICĂ-B Marcela Cândea¹, G. Oltean¹, Smaranda Demian¹, I. Macarie¹, Bogdana Dorcioman² ¹ UMF Tg-Mure ş, Clinica Medicală I-Hematologie ² Spitalul Clinic Judeţean Tg-Mure ş, Laboratorul Central NEOPLAZIILE MIELOPROLIFERATIVE ŞI SARCINA. EXPERIENŢA CENTRULUI DE TRANSPLANT MEDULAR FUNDENI. Emilia Niculescu-Mizil, Iulia Ursuleac Centrul de Transplant Medular. Institutul Clinic Fundeni DIFICULTA ŢI ÎN DIAGNOSTICUL ŞI TRATAMENTUL DEFICITULUI DOBANDIT DE VITAMINA K LA ADULT STUDIU DE CAZ Ana-Maria Moldovianu, Răzvan Stoia Institutul Clinic Fundeni, Departamentul de Hematologie şi Transplant Medular MANIFESTARE TARDIVĂA SINDROMULUI DE DIFERENŢIERE (DE ATRA) STUDIU DE CAZ Ana-Maria Moldovianu, Răzvan Stoia Institutul Clinic Fundeni, Departamentul de Hematologie şi Transplant Medular TBC MILIARA LA UN PACIENT CU LEUCEMIE GRANULOCITARĂCRONICĂTRATAT CU INHIBITORI DE TIROZIN KINAZA L. Urian¹, L. Petrov¹, D. Bucerzan¹, M. Patiu¹,C. Basarab¹, M. Flonta², A. Bojan¹, A. Cucuianu¹, A. Vasilache¹, T. Torok¹, M. Zdrenghea¹, C. Truica³ 1. Institutul Oncologic Ion Chiricu ţă, Cluj Napoca 2. Clinica Boli Infecţioase, Cluj Napoca 3. Spitalul judeţean, Hematologie Baia Mare AUTOTRANSPLANTUL ÎN MIELOMUL MULTIPLU CU FACTORI DE PROGNOSTIC NEFAVORABIL - PREZENTARE DE CAZ. Nicoleta Berbec, Elena Coles, Mihaela Lebedenco, Cristina Negotei, Andrei Coli ţă, Anca Lupu Clinica de Hematologie, Spitalul Clinic Colţea NELARABINA TERAPIE DE SALVARE ÎN LAL T. Melen Brînza, Oana Diana Agatinei, B.Ionescu Central de Hematologie şi Transplant Medular, Institutul Clinic Fundeni, Bucureşti 22

24 Joi 11 octombrie SALA COLOCVIUM Sesiune Asistente Medicale ADMINISTRAREA DE ARANESP ÎN TRATAMENTUL ANEMIEI Nedelcu Elena, Berbece Liliana, Coman Elena Spitalul Universitar de Urgenţa Militar Central, Bucuresti, Secţia Oncologie/Hematologie CONTROLUL EMEZEI INDUSA DE CHIMIOTERAPIE CU PALONOSETRON (ALOXI) Paula Sârbu Centrul de Hematologie si Transplant Medular,Institutul Clinic Fundeni, București ROLUL ASISTENTEI MEDICALE ÎN ÎNGRIJIREA BOLNAVILOR CU NEUTROPENIE POST CHIMIOTERAPIE Croitoru Daniela Centrul de Hematologie şi Transplant Medular, Institutul Clinic Fundeni,Bucureşti COMBATEREA STRESULUI PSIHIC Filip Maria Centrul de Hematologie şi Transplant Medular, Institutul Clinic Fundeni,Bucureşti AMFOTERICINA B - TRATAMENTUL REVOLUŢIONAR AL INFECŢIILOR FUNGICE Constantin Nela Centrul de Hematologie şi Transplant Medular,Institutul Clinic Fundeni, Bucureşti TRANSPLANTUL CU CELULE STEM HEMATOPOIETICE IN TERAPIA BOLILOR MALIGNE Ghelase Rodica Centrul de Hematologie şi Transplant Medular,Institutul Clinic Fundeni, Bucureşti ANEMIE APLASTICA FOARTE SEVERA CU ETIOPATOGENIE COMPLEXA. PREZENTARE DE CAZ Vişan L., Dima D., Frinc I., Patiu M., Tantau D., Pop S., Nagy I., Vermeşan M., Cucuianu A. Institutul Oncologic «Ion Chiricu ţă» Cluj-Napoca, secţia Hematologie ACTUL MEDICAL-ARTA SI PROFESIONALISM Mircea Doina Centrul de Hematologie si Transplant Medular, Institutul Clinic Fundeni, Bucuresti SOCUL ÎN AFECŢIUNILE HEMATOLOGICE Viorica Manea Centrul de Hematologie si Transplant Medular, Institutul Clinic Fundeni, Bucuresti MABTHERA ADMINISTRATA SUBCUTAN VERSUS MABTHERA ADMINISTRATA INTRAVENOS. Livia Neacsu Spitalul Clinic Colţea - Clinica Hematologie, Bucureşti 23

25 Simona Soverini, PhD Simona Soverini, PhD, is Assistant Professor at the Department of Hematology/Oncology L. and A. Seragnoli of the University of Bologna, in Italy. Dr. Soverini graduated with a degree in Biological Sciences in 1999 and subsequently earned a PhD in clinical and experimental hematology from the University of Bologna. She currently works at the Molecular Biology Unit of the Department of Hematology/Oncology L. and A. Seragnoli. Since 2003, her main research interests lie in the biology and therapy of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblast leukemia (ALL), with a particular focus on the mechanisms of resistance to tyrosine kinase inhibitors. In this field, she has been working with many internationally renowned scientists and has earned honors and awards. Over the past years, Dr Soverini is also exploring on the application of genome-wide technologies - next-generation sequencing in particular - as research and diagnostic tools. Dr. Soverini has participated as invited speaker or chairman in more than a hundred national and international meetings. She also serves as a reviewer for journals like Blood, Leukemia, Haematologica and Clinical Cancer Research, for the European HematologyAssociation (EHA) and for theamerican Society of Hematology (ASH). Dr. Soverini sits in the Molecular Biology Committee of the Italian GIMEMA CML Working Party, and as an active member of the European LeukemiaNet, she has coordinated the panel of CML experts that in 2011 compiled the recommendations for BCR-ABL kinase domain mutation analysis in CML patients treated with tyrosine kinase inhibitors. Dr. Soverini is the first or contributing author of over 80 publications in international peer-reviewed journals. Professor Adrian Newland Department of Haematology, Barts and the London School of Medicine and Dentistry, London, UK a.c.newland@qmul.ac.uk, ukitpregistry.com 24

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