Kernmodul Physiologie SS 2015

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1 Kernmodul Physiologie SS 2015 The present module intends to provide a deeper understanding of physiology, ranging from molecular and cell physiology to integrative human physiology. You will be exposed to present research areas in physiology at Charité and improve your scientific knowledge and research skills including data collection, analyses, interpretation, and discussing peerreviewed international publications. In addition to real data collections to be performed in class and complementing the lectures and seminars, the goals of the module will cover very accessible topics that include, but are not limited to basics of biosignal recording, processing, and analyses (e.g. filtering, artifact correction, smoothing, mobile monitoring technologies, validation of new technologies, etc.), chronobiology, brain function (EEG), physical activity, body composition technologies, electrophysiological techniques in epithelial physiology, optical methods (confocal laser scanning microscopy, super resultion microscopy, freeze fracture electron microscopy), homology modelling of protein structure. This framework of topics will be delivered by close collaboration between the Institut für klinische Physiologie, CBF and Institut für Physiologie, CCM, each covering their respective expertise in physiological research. On the following pages you will get some detailed information on class requirements, dates and times. We are looking forward to an exciting class and to welcoming you soon! Dr. Andreas Zakrzewicz Institut für Physiologie, CCM PD Dr. Dorothee Günzel Institut für klinische Physiologie, CBF

2 Please note: (1) Max Number of Students The class is limited to a max. of 10 students. You can sign up for the class via the Campus Management System. Please make sure that you sign up for all three classes, i.e. CUB820, CUB820a, and CUB820b Here is a link to the course catalog: and to our website: Should you have any further questions on registering, please get in touch with our teaching secretary Mrs. Cornelia Marruhn ( cornelia.marruhn@charite.de). (2) Successful completion of module In addition to regular attendance you will have to pass an oral exam of about 20 min at the end of the term. The result of this exam will mainly determine your final mark. However, it is also a prerequisite of this module to deliver presentations to the class. You will be asked to give two presentations of approx. 20 min plus 10 min discussion. You will also chair sessions (lead the discussion). You will get credit for these presentations and they will be considered as part of your final mark! (3) Dates and times Typically, the lectures and seminars are held on Thursdays, h to h, and h to h, respectively. The class termed Übung is scheduled as a block and will be given 4 times on Mondays, h. Due to holidays some classes may be swopped.

3 (4) Dates and times Very importantly, please also check the exact location for each class. The first half of the semester (until June 1) will be conducted at Charite Universitätsmedizin Berlin, Campus Mitte. Depending on the type of class different rooms may have been booked. The second half of the semester (until July 16) will be conducted at Charite Universitätsmedizin Berlin, Campus Benjamin Franklin (Hindenburgdamm 30). Meeting point: Institute for Clinical Physiolog, Use elevator 17 or 18 to 5 th floor, turn right, through the glass door stating that patients are not admitted (5) First and final class The module will start with an introduction and seminar on April 13. The final class will be your oral exam on July 16. (6) Language The module will be taught in English or German, depending on students preference.

4 Table 1. Overview of Term Date Time Place Type Topic April 13 April 16 April 23 April 30 May 4 May 7 May 14 May 21 May 28 June 1 June 4 June 4 June 11 June 11 Monday June 15 June 18 June 18 CBF Günzel, Zakrzewicz Introduction Preparing a Scientific Presentation CCM VL+S Zakrzewicz Physiology of red blood cells CCM VL+S Habazettl some remarks on physiological measurements CCM VL+S Reglin blood vessel structure CCM Übung Zakrzewicz blood analyses CCM VL+S Reglin Microcirculation Public Holiday CCM VL+S Gunga excercise physiology CCM VL+S Gunga physiology in extreme environments CCM Übung Gunga body composition Introduction to Epithelial Physiology CBF VL Piontek Optical methods I Flow Cytometry, Confocal Laser Scanning Microscopy Electrophysiology I, Ussing chamber and Epithelial Impedance Spectroscopy CBF Übung Günzel, Piontek Group 1: Impedance spectroscopy Group 2: Confocal Laser Scanning Microscopy Electrophysiology II Voltage Clamp / Patch Clamp

5 Monday June 22 June 25 June 25 July 2 July 2 July 9 July 9 July 16 12:00 CBF Übung Günzel, Piontek Group 1: Confocal Laser Scanning Microscopy Group 2: Impedance spectroscopy CBF VL Piontek, Krug, Rosenthal Optical methods II: Super Resolution Microscopy, Freeze Fracture electron microscopy, Microfluorimetry CBF VL Piontek Homology Modelling CBF Oral Exam 20 min oral exam

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