ECZEMA ECZEMA CANNOT BE CURED, BUT IT CAN BE MANAGED

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1 ECZEMA WHO: 1 in 5 children in the UK have eczema. Most children grow out of it, yet recently the number of adults diagnosed with atopic eczema has increased, up to 10% of adults in UK Mostly people who are allergic in general (hayfever, asthma, ), triggered by stress as well WHAT: Dry skin, itching, scaling, red spots, erosions, irritajon, acute or chronic inflammajon WHERE: Face trunk, upper & lower limbs, flexor surfaces, (Contact eczema: hands, feet) ECZEMA CANNOT BE CURED, BUT IT CAN BE MANAGED

2 HEALTHY SKIN Cells are Jghtly held together in brick & mortar structure Ø No irritants possible to enter the skin from the outside Ø No water is lost

3 ECZEMA SKIN The barrier is damaged, cells are less Jghtly held together Ø Allergens and irritants can enter and cause inflammajon: red and itchy Ø Water is lost and skin becomes dry

4 TRADITIONAL ECZEMA TREATMENTS A B A. Emollients: mainly rehydrate the skin B. Steroid creams: mainly regulate the inflammahon

5 DERMALEX ECZEMA AcHvates the skin own repair mechanism, restoring the barrier 2. Avoids inflammahon and repairs symptoms 3. Moisturising micro layer on the skin that protects and soothes

6 DERMALEX ECZEMA PaJents tested had an average improvement of their eczema symptoms of 83% (SCORAD 83) PaJents tested had an average improvement of their contact eczema symptoms of of 71% (SCORAD 71, HECSI 72%) Source: Open label MulJ Center Clinical ObservaJon Study Into the overall efficacy of Atopifin Cream for Babies, Toddlers and Young children with Atopic DermaJJs, Dr. J. Buzasi e.a, 2009.

7 WHAT IS PSORIASIS? WHO: Psoriasis affects around 2% of people in the UK. It can start at any age, but most ohen develops between the ages of 11 and 45. It has a devastajng impact on a pajent s Quality of Life WHAT: Dry, red skin lesions, known as plaques, covered in silver scales (dead skin cells), ohen itchy and sore WHERE: Occurs on elbows, knees, face, palms, back, PSORIASIS CANNOT BE CURED, BUT IT CAN BE MANAGED

8 HEALTHY SKIN Normal skin cells take 21 to 28 days to replace themselves Skin cells are Jghtly packed together in brick & mortar structure = barrier No exterior irritants can enter No water is lost

9 PSORIASIS SKIN Changes in the immune system trigger LC- cells to become overacjve, acjvajng T- cells up to 10x more to produce skin cells Skin cells replace themselves in 2 to 6 days AccumulaJon of skin cells on the surface into silvery plaques Barrier is damaged: Allergens and irritants can enter and cause inflammajon: red and itchy Water is lost and skin becomes dry

10 TRADITIONAL PSORIASIS TREATMENTS A C D B A. Emollients: mainly rehydrate the skin B. Steroid creams: mainly regulate the inflammahon C. Coal tar preparahons: unknown mechanism of achon yet makes skin more sensihve to light and helps slow down the rapid proliferahon D. Vitamin D analogues: believed to work by slowing down hyperproliferahon

11 DERMALEX PSORIASIS Normalises skin cell producjon Blocks the acjvajon of T- cells by the Langerhans cells Decreases the producjon of skin cells and their maturajon Jme 2. Restores the skin barrier 3. Reduces inflammajon 4. Creates a protecjve micro shield that moisturises and soothes

12 DERMALEX PSORIASIS PaJents tested had an average improvement of their Psoriasis symptoms of 71% (80% PASI 50, 50% PASI 75) Source: Clinical study Dermatology and Psoriasis Clinics, Laudau & Kandel, Germany, 2010; At Józsefváros Health Center, Budapest, Hungary, 2010

13 WHAT IS ROSACEA? WHO: Rosacea affects up to 1 in 10 people. It most commonly affects people with fair skin, but can also occur in people of Asian and African origin. Rosacea occurs in both men and women and may occur at any age. However, it typically begins aher the age of 30. Middle- aged women are more at risk due to hot flushes caused by the menopause. WHAT: Symptoms vary per person, common is flushing, persistent redness, visible blood vessels. WHERE: Face (cheeks and nose) ROSACEA CANNOT BE CURED, BUT IT CAN BE MANAGED

14 ROSACEA SKIN Skin s natural barrier is damaged, making it more suscepjble for interior and exterior insults that can aggravate Rosacea (e.g. UV sunlight, stress, alcohol, certain foods, cold, Symptoms begin with a tendency to blush or flush Over Jme, redness become more persistent, visible blood vessels appear Leh untreated, bumps and pimples may develop

15 DERMALEX ROSACEA 1.Restores the barrier 2. Protects from one of the main triggers 1. Tri- solve complex: Creates a protecjve film by combining trehalose to provide an immediate moisturizing effect, together with key skin elements (cholesterol, ceramide and free fauy acids) to restore the skin s natural barrier. 2. UV filters (UVA + UVB) 4. Soothes & calms the skin 3. Reduces flare ups 3. RestoraJon of barrier and green pigment that covers red flushes, managing stress levels and reducing new flare ups 4. Via combinajon of soothing, protecjve and calming ingredients: Bisabolol, Esculin, TriJcum Vulgare Germ Extract, Echinacea AngusJfolia, Boswellia Serrata, Zanthoxylum Bungeanum Fruit Extract

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