Sinemet (Parkinson's Disease) - Forecast and Market Analysis to 2022

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1 Brochure More information from Sinemet (Parkinson's Disease) - Forecast and Market Analysis to 2022 Description: Sinemet (Parkinson s Disease) - Forecast and Market Analysis to 2022 Summary Parkinson s disease is a progressive condition that is characterized by bradykinesia, muscular rigidity, tremor, and postural instability. As the second most common neurodegenerative disorder, Parkinson s disease may affect individuals of any age but prevalence is increased with age and it is most common in the elderly. Dopaminergic therapies have been fairly effective in treating bradykinesia, but several unmet needs remain. Some needs will be met during the forecast period from , while others, such as the need for disease-modifying drugs, will remain. GlobalData expects that advancements will be made in levodopa administration and that four new molecular entities will be introduced to the market by 2022, these factors along with increased patient numbers from an aging population will drive the market during the forecast period. Sinemet (carbidopa and levodopa), developed by Merck & Co., is considered one of the gold standards for treatment in Parkinson s disease. It is used for the control of motor symptoms in Parkinson s disease and other Parkinsonian syndromes. Sinemet does not slow the neurodegenerative process in Parkinson s disease, and over time patients responsiveness to therapy may change as they enter more advanced stages of the disease. Scope - Overview of Parkinson s disease, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape. - Detailed information on Sinemet including product description, safety and efficacy profiles as well as a SWOT analysis. - Sales forecast for Sinemet for the top eight countries from 2012 to Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan and Brazil. Reasons to buy - Understand and capitalize by identifying products that are most likely to ensure a robust return - Stay ahead of the competition by understanding the changing competitive landscape for Parkinson s disease - Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential - Make more informed business decisions from insightful and in-depth analysis of Sinemet performance - Obtain sales forecast for Sinemet from in the top eight countries (the US, France, Germany, Italy, Spain, the UK, Japan and Brazil). Contents: 1 Table of Contents 1 Table of Contents 1.1 List of Tables 1.2 List of Figures 2 Introduction 2.1 Catalyst 2.2 Related Reports 3 Disease Overview 3.1 Etiology and Pathophysiology Etiology Pathophysiology Prognosis Quality of Life 3.2 Symptoms

2 4 Disease Management 4.1 Overview Diagnosis - The UK Brain Bank Criteria Treatment Guidelines and Leading Prescribed Drugs 4.2 Treatment Synopsis Dopaminergic Therapy Classes Treatment of Parkinson s Disease by Stage Other Treatment Options 4.3 Parkinson s Disease Assessment Scales Unified Parkinson s Disease Rating Scale (UPDRS) Hoehn and Yahr Clinical Staging Other Clinical Assessments 5 Competitive Assessment 5.1 Overview 5.2 Strategic Competitor Assessment 5.3 Product Profiles - Levodopa Combination Therapy 6 Sinemet (carbidopa/levodopa) 6.1 Overview 6.2 Efficacy 6.3 Safety 6.4 SWOT Analysis 6.5 Forecast 7 Appendix 7.1 Bibliography 7.2 Abbreviations 7.3 Methodology 7.4 Forecasting Methodology Diagnosed Parkinson s Disease Patients Percent Drug-Treated Patients General Pricing Assumptions Compliance Assumptions Individual Drug Assumptions Generic Erosion 7.5 Physicians and Specialists Included in this Study 7.6 About the Authors Author Global Head of Healthcare 7.7 About Us 7.8 Disclaimer 1.1 List of Tables Table 1: Symptoms of Parkinson s Disease Table 2: UK Brain Bank Diagnostic Criteria Table 3: Diagnosis and Treatment Guidelines for Parkinson s Disease Table 4: Most Prescribed Drugs for Parkinson s Disease by Class in the Global Markets, 2014 Table 5: Dopaminergic Therapy in Parkinson s Disease Table 6: UPDRS Clinical Assessment of Disease Severity Table 7: Parkinson s Disease Assessment Scales Used in Clinical Trials Table 8: Treatment of Motor Symptoms in Parkinson s Disease Table 9: Leading Treatments for Parkinson s Disease, 2014 Table 10: Product Profile - Sinemet Table 11: Sinemet SWOT Analysis, 2014 Table 12: Global Sales Forecasts ($m) for Sinemet, Table 13: Global Sales Forecasts ($m) for Sinemet CR, List of Figures Figure 1: Overview - L-dopa Metabolism and Inhibitor Classes Figure 2: Overview - Treatment of Motor Symptoms of Parkinson s Disease Ordering: Order Online -

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4 Page 1 of 2 Fax Order Form To place an order via fax simply print this form, fill in the information below and fax the completed form to (from USA) or (from Rest of World). If you have any questions please visit Order Information Please verify that the product information is correct and select the format(s) you require. Product Name: Sinemet (Parkinson's Disease) - Forecast and Market Analysis to 2022 Web Address: Office Code: Product Formats Please select the product formats and quantity you require: SC Single User: Site License: Enterprisewide: Quantity USD 3495 USD 6990 USD Contact Information Please enter all the information below in BLOCK CAPITALS Title: Mr Mrs Dr Miss Ms Prof First Name: Last Name: Address: * Job Title: Organisation: Address: City: Postal / Zip Code: Country: Phone Number: Fax Number: * Please refrain from using free accounts when ordering (e.g. Yahoo, Hotmail, AOL)

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