Endocrinology of the Female Reproductive Axis

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "Endocrinology of the Female Reproductive Axis"

Transcription

1 Endocrinology of the Female Reproductive Axis girlontheriver.com Geralyn Lambert-Messerlian, PhD, FACB Professor Women and Infants Hospital Alpert Medical School at Brown University Women & Infants BROWN

2 Learning objectives 1. Diagram the main components of the female reproductive axis 2. Describe basic immunoassay methods for measurement of reproductive hormones 3. List the primary hormones secreted in pregnancy

3 Overview of the female reproductive axis Gonadotropin releasing hormone Gonadotropin hormones Follicle stimulating hormone Luteinizing hormone (Gonad) Inhibin Modified from Hiller-Sturmhöfel and Bartke, Alcohol Health & Research World, 1998

4 Ovarian Physiology FSH Kaipia & Hsueh, Ann Rev Physiol, 1997

5 Normal menstrual cycle FOLLICULAR PHASE Day 1 FSH Thorneycroft, Am J Obstet Gynecol, 1971

6 Developing ovarian follicle GRANULOSA CELL THECA CELL ANTRUM Sherwood, Fundamentals of Physiology, 1991.

7 Steroid biosynthesis in ovarian follicles Granulosa cell Theca cell Griffin and Ojeda, Textbook of Endocrine Physiology, 2004

8 Estradiol Follicular phase of the menstrual cycle

9 Inhibin B Inhibin B is secreted during the follicular phase of the menstrual cycle FSH Estradiol Groome et al, JCEM;1996

10 Feedback regulation of the menstrual cycle Fauci et al. Harrison s Principles of Internal Medicine, 17 th edition

11 Mid-cycle LH FSH Estradiol

12 Ovulatory LH surge Development of the corpus luteum Sherwood, Fundamentals of Physiology, 1991.

13 Steroid biosynthesis in corpus luteum

14 Luteal phase of the menstrual cycle LUTEAL PHASE Progesterone Estradiol

15 Menstrual Cycle Summary Sherwood, Fundamentals of Physiology, 1991.

16 Inhibin A is secreted by the corpus luteum Inhibin A Groome et al, 1996; JCEM

17 Immunometric (sandwich) assay Y Y Y Y Amount of signal Sample or standard concentration FSH FSH Y Y Y Y Y Y ANTIBODY

18 Competitive immunoassay Exogenously added, labelled hormone % Binding of radioactivity Sample or standard concentration Y Y Y Endogenous hormone in the sample ANTIBODY

19 Sample reference data Menstrual cycle Follicular Ovulatory Luteal Menopause FSH (miu/ml) LH (miu/ml) < Estradiol (pg/ml) X 3.67 = pmol/l Progesterone (ng/ml) X 3.18 = nmol/l < < 30 < < Inhibin A (pg/ml) < 10 Inhibin B (pg/ml) < 16 Women and Infants Hospital

20 Hormone monitoring for fertility treatment 37 year old woman with history of infertility History of irregular menstrual cycles and infertility Normal anatomy Treated with high dose exogenous FSH to stimulate ovaries Serial estradiol levels (pg/ml) Day Day Day Day 7 1,272 What do these results indicate? Does this woman have a good chance of pregnancy success?

21 Hormone monitoring for fertility treatment 37 year old woman with history of infertility History of irregular menstrual cycles and infertility Normal anatomy Treated with high dose exogenous FSH to stimulate ovaries Serial estradiol levels (pg/ml) Day Day Day Day 7 1,272 What do these results indicate? About follicles have developed Does this woman have a good chance of pregnancy success? YES!

22 Hormones in Pregnancy Fetal-placental unit

23 Placental hormones Human chorionic gonadotropin Estradiol Progesterone

24 Sample reference data hcg in pregnancy Weeks from hcg (miu/ml) conception , ,000-20, , ,000 2 nd trimester 20,000-60,000 3 rd trimester ,000 Women and Infants Hospital

25 Monitoring pregnancy viability 30 year old woman Pregnant by home urine test Presents with some vaginal bleeding at ER Gestational age estimate = 4 weeks Serial hcg (miu/ml) Day 1 3,000 Day 2 4,720 Day 3 7,590 Is this a viable pregnancy?

26 Monitoring pregnancy viability 30 year old woman Pregnant by home urine test Presents with some vaginal bleeding at ER Gestational age estimate = 4 weeks Serial hcg (miu/ml) Day 1 3,000 Day 2 4,720 Day 3 7,590 Is this a viable pregnancy? YES! hcg should rise by a minimum of 53% every 48 hours in early pregnancy Barnhart et al., Obstet Gynecol, 2004

27 Progesterone in pregnancy ng/ml Yen and Jaffe, Reproductive Endocrinology, 1991

28 Estrogens in pregnancy Gabbe, Niebyl and Simpson, Obstetrics, 1991.

29 Estriol synthesis in pregnancy Estradiol Estrone Sulfatase Aromatase

30 Summary Female reproductive hormones annsrunningcommentary.com Vary with menstrual cycle day, pregnancy and menopause Require samples timed to cycle day and clinical information for proper interpretation Are useful tools to evaluate fertility and pregnancy health

The Menstrual Cycle. Model 1: Ovarian Cycle follicular cells

The Menstrual Cycle. Model 1: Ovarian Cycle follicular cells The Menstrual Cycle REVIEW questions to complete before starting this POGIL activity 1. Gonads produce both gametes and sex steroid hormones. For the female, name the: A. gonads ovaries B. gametes oocyte/ovum/egg

More information

1. AMOUNT OF FSH PRESENT

1. AMOUNT OF FSH PRESENT The Menstrual Cycle Name Date Period PRE-LAB 1. Write down three facts you know about the menstrual cycle. A. B. C. FOLLICULAR PHASE Within the ovaries are located many egg cells. Each egg is enclosed

More information

From Menses to Menopause: How Hormones Can Affect Blood Glucose Levels. Christine Day, RN, MS, CNS-BC Lake Superior College

From Menses to Menopause: How Hormones Can Affect Blood Glucose Levels. Christine Day, RN, MS, CNS-BC Lake Superior College From Menses to Menopause: How Hormones Can Affect Blood Glucose Levels Christine Day, RN, MS, CNS-BC Lake Superior College Overview Will review hormonal changes over the female lifespan Discuss the effects

More information

The Menstrual Cycle, Hormones and Fertility Treatment

The Menstrual Cycle, Hormones and Fertility Treatment The Menstrual Cycle, Hormones and Fertility Treatment How many of us understand how our monthly cycle works? Every 28 days (or thereabouts), between the ages of around 13 and 51, a woman will release a

More information

Anatomy and Physiology of Human Reproduction. Module 10a

Anatomy and Physiology of Human Reproduction. Module 10a This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this

More information

Unit 3 REPRODUCTIVE SYSTEMS AND THE MENSTRUAL CYCLE

Unit 3 REPRODUCTIVE SYSTEMS AND THE MENSTRUAL CYCLE Unit 3 REPRODUCTIVE SYSTEMS AND THE MENSTRUAL CYCLE Learning Objectives By the end of this unit, the learner should be able to: Explain the importance of understanding the male and female reproductive

More information

Reproduction and its Hormonal Control

Reproduction and its Hormonal Control Reproduction and its Hormonal Control Page 1 Reproduction and its Hormonal Control Different mammals have different patterns of reproduction Eg mammals, rats and mice can breed all year round, whereas

More information

Prediction of Pregnancy Outcome Using HCG, CA125 and Progesterone in Cases of Habitual Abortions

Prediction of Pregnancy Outcome Using HCG, CA125 and Progesterone in Cases of Habitual Abortions Prediction of Pregnancy Outcome Using HCG, CA125 and Progesterone in * (MBChB, FICMS, CABOG) **Sawsan Talib Salman (MBChB, FICMS, CABOG) ***Huda Khaleel Ibrahim (MBChB) Abstract Background: - Although

More information

SYNCHRONIZATION OF CATTLE

SYNCHRONIZATION OF CATTLE UNDER ESTRUS SYNCHRONIZATION OF CATTLE FS921C Robin Salverson, Extension Livestock Educator, Harding County, and George Perry, Extension Beef Reproduction and Management Specialist Reproductive failure

More information

The Endocrine System

The Endocrine System Essentials of Human Anatomy & Physiology Elaine N. Marieb Seventh Edition Chapter 9 The Endocrine System Slides 9.1 9.48 Lecture Slides in PowerPoint by Jerry L. Cook The Endocrine System Second messenger

More information

Smoking and Age of Menopause. Women who smoke experience menopause an average of 2 years earlier than women who do not smoke.

Smoking and Age of Menopause. Women who smoke experience menopause an average of 2 years earlier than women who do not smoke. Menopause Menopause Feared event To many, it indicates old age - a sign of life coming to a close. Many expect a difficult psychological adjustment to menopause (bad press, bad jokes). Menopause Effect

More information

INFERTILITY/POLYCYSTIC OVARIAN SYNDROME. Ovulatory Dysfunction: Polycystic ovarian syndrome (PCOS)

INFERTILITY/POLYCYSTIC OVARIAN SYNDROME. Ovulatory Dysfunction: Polycystic ovarian syndrome (PCOS) Introduction Infertility is defined as the absence of pregnancy following 12 months of unprotected intercourse. Infertility may be caused by Ovulatory Dysfunction, Blocked Fallopian Tubes, Male Factor

More information

The objectives of this chapter are: To provide an understanding of the various stimulation protocols used in IVF To enable the student to understand

The objectives of this chapter are: To provide an understanding of the various stimulation protocols used in IVF To enable the student to understand 1 The objectives of this chapter are: To provide an understanding of the various stimulation protocols used in IVF To enable the student to understand the factors affecting the choice of protocol based

More information

CYCLE EVALUATION. Please review this guide carefully. I. Early In Cycle. A. Selection of the Dominant Follicle (~ Day 3)

CYCLE EVALUATION. Please review this guide carefully. I. Early In Cycle. A. Selection of the Dominant Follicle (~ Day 3) CYCLE EVALUATION In order to evaluate how well you ovulate, we will see you on three days during your menstrual cycle. Early in the cycle you select a dominant follicle, on or about the third day of your

More information

Reduced Ovarian Reserve Is there any hope for a bad egg?

Reduced Ovarian Reserve Is there any hope for a bad egg? Reduced Ovarian Reserve Is there any hope for a bad egg? Dr. Phil Boyle Galway Clinic, 19 th March 2014 For more information on Low AMH see www.napro.ie Anti Mullerian Hormone AMH levels are commonly measured

More information

Age and Fertility. A Guide for Patients PATIENT INFORMATION SERIES

Age and Fertility. A Guide for Patients PATIENT INFORMATION SERIES Age and Fertility A Guide for Patients PATIENT INFORMATION SERIES Published by the American Society for Reproductive Medicine under the direction of the Patient Education Committee and the Publications

More information

SPONTANEOUS AND PHARMACOLOGICALLY INDUCED REMISSIONS IN PATIENTS WITH PREMATURE OVARIAN FAILURE

SPONTANEOUS AND PHARMACOLOGICALLY INDUCED REMISSIONS IN PATIENTS WITH PREMATURE OVARIAN FAILURE SPONTANEOUS AND PHARMACOLOGICALLY INDUCED REMISSIONS IN PATIENTS WITH PREMATURE OVARIAN FAILURE David Kreiner, M. D. * Kathleen Droesch, M.D. Daniel Navot, M.D. Richard Scott, M.D. Zev Rosenwaks, M.D.

More information

Timing is everything. Ovulation Tracking. Patient Information Booklet

Timing is everything. Ovulation Tracking. Patient Information Booklet Timing is everything Ovulation Tracking Patient Information Booklet Contents Getting pregnant naturally 3 Getting pregnant the basics 3 What is ovulation? 3 Menstrual cycle 4 When does ovulation take place?

More information

Preventive Powers of Ovulation and Progesterone

Preventive Powers of Ovulation and Progesterone Preventive Powers of Ovulation and Progesterone Detection of Ovulation by Dr. Jerilynn C. Prior, Scientific Director, Centre for Menstrual Cycle and Ovulation Research. I believe that ovulation with a

More information

Hormonal Oral Contraceptives: An Overview By Kelsie Court. A variety of methods of contraception are currently available, giving men and

Hormonal Oral Contraceptives: An Overview By Kelsie Court. A variety of methods of contraception are currently available, giving men and Hormonal Oral Contraceptives: An Overview By Kelsie Court A variety of methods of contraception are currently available, giving men and women plenty of options in choosing a method suitable to his or her

More information

Understanding Blood Tests - Pregnancy/Fertility Monitoring by Beth Anne Ary M.D

Understanding Blood Tests - Pregnancy/Fertility Monitoring by Beth Anne Ary M.D Understanding Blood Tests - Pregnancy/Fertility Monitoring by Beth Anne Ary M.D Blood tests are the most common and most important method of monitoring pregnancy-- both assisted pregnancies, and unassisted.

More information

The Analytical & Clinical Complexities of Human Chorionic Gonadotropin Tests

The Analytical & Clinical Complexities of Human Chorionic Gonadotropin Tests The Analytical & Clinical Complexities of Human Chorionic Gonadotropin Tests David G. Grenache, PhD, MT(ASCP), DABCC University of Utah & ARUP Laboratories Salt Lake City, UT david.grenache@path.utah.edu

More information

Page 1. 1. The production of monoploid cells by spermatogenesis occurs in (1) zygotes (3) ovaries (2) testes (4) meristems

Page 1. 1. The production of monoploid cells by spermatogenesis occurs in (1) zygotes (3) ovaries (2) testes (4) meristems 1. The production of monoploid cells by spermatogenesis occurs in (1) zygotes (3) ovaries (2) testes (4) meristems Base your answers to questions 2 and 3 on the diagram below of the female reproductive

More information

Systematic review by: Dr. Ashraf Ahmed ElDaly, M.Sc., M.D.

Systematic review by: Dr. Ashraf Ahmed ElDaly, M.Sc., M.D. Role of luteinizing hormone supplementation in the follicular phase and pregnancy, during controlled ovarian hyperstimulation in in vitro fertilization Systematic review by: Dr. Ashraf Ahmed ElDaly, M.Sc.,

More information

SAMPLE PROCEDURE 1029-3, 09/11

SAMPLE PROCEDURE 1029-3, 09/11 SAMPLE PROCEDURE This Sample Procedure is not intended as a substitute for your facility s Procedure Manual or reagent labeling, but rather as a model for your use in customizing for your laboratory s

More information

Clearblue Fertility Monitor

Clearblue Fertility Monitor The Clearblue Fertility Monitor is: Accurate - 99% accurate in detecting the LH surge in urine Unique - provides daily fertility status by measuring two urinary hormones LH and E3G Effective - helps women

More information

Elevated serum progesterone on the day of HCG administration in IVF is associated with a higher pregnancy rate in polycystic ovary syndrome

Elevated serum progesterone on the day of HCG administration in IVF is associated with a higher pregnancy rate in polycystic ovary syndrome Human Reproduction vol.14 no.3 pp.601 605, 1999 Elevated serum progesterone on the day of HCG administration in IVF is associated with a higher pregnancy rate in polycystic ovary syndrome Nicola Doldi

More information

REPRODUCTIVE aging is associated with a decline in

REPRODUCTIVE aging is associated with a decline in 0021-972X/99/$03.00/0 Vol. 84, No. 1 Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright 1999 by The Endocrine Society Female Reproductive Aging Is Marked by Decreased Secretion

More information

Welcome to chapter 8. The following chapter is called "Monitoring IVF Cycle & Oocyte Retrieval". The author is Professor Jie Qiao.

Welcome to chapter 8. The following chapter is called Monitoring IVF Cycle & Oocyte Retrieval. The author is Professor Jie Qiao. Welcome to chapter 8. The following chapter is called "Monitoring IVF Cycle & Oocyte Retrieval". The author is Professor Jie Qiao. The learning objectives of this chapter are 2 fold. The first section

More information

Anatomy of the Male Reproductive System

Anatomy of the Male Reproductive System Anatomy of the Male Reproductive System External genitalia (can be seen on the body surface) penis scrotum Internal genitalia (can t be seen on the body surface) sperm producing organs testes ducts that

More information

Artificial insemination

Artificial insemination Artificial insemination What is involved? Artificial insemination is an assisted reproduction technique that consists of inserting laboratory-treated spermatozoa into the woman s uterus or cervical canal.

More information

HOW IS OVARIAN RESERVE ASSESSED?

HOW IS OVARIAN RESERVE ASSESSED? HOW IS OVARIAN RESERVE ASSESSED? The majority of indicators we have to assess OR assess egg quantity rather than egg quality and these two do not always go hand in hand. No individual test is a perfect

More information

Guidelines for Ordering Serum Levels of Gonadotropins (FSH, LH) and Prolactin CLP 021 Revised June, 2008 (Replaces October 2000 version)

Guidelines for Ordering Serum Levels of Gonadotropins (FSH, LH) and Prolactin CLP 021 Revised June, 2008 (Replaces October 2000 version) Guidelines for Ordering Serum Levels of Gonadotropins (FSH, LH) and Prolactin CLP 021 Revised June, 2008 (Replaces October 2000 version) 1. Scope This laboratory Guideline is intended to assist community

More information

Issues Relevant to Endocrine Disruptor Screening

Issues Relevant to Endocrine Disruptor Screening Concepts of Endocrinology: Issues Relevant to Endocrine Disruptor Screening Raphael J. Witorsch, Ph.D. Professor Emeritus Physiology and Biophysics School of Medicine Virginia i i Commonwealth University

More information

Artificial insemination with donor sperm

Artificial insemination with donor sperm Artificial insemination with donor sperm Ref. 123 / 2009 Reproductive Medicine Unit Servicio de Medicina de la Reproducción Gran Vía Carlos III 71-75 08028 Barcelona Tel. (+34) 93 227 47 00 Fax. (+34)

More information

Hormone Replacement Therapy For Women

Hormone Replacement Therapy For Women Hormone Replacement Therapy For Women Bio-identical Hormone Replacement Therapy Gail Eberharter M.D. May 10, 2009 There are three main hormones that are responsible for the menstrual cycle, sexual drive

More information

FERTILITY AND AGE. Introduction. Fertility in the later 30's and 40's. Am I fertile?

FERTILITY AND AGE. Introduction. Fertility in the later 30's and 40's. Am I fertile? FERTILITY AND AGE Introduction Delaying pregnancy is a common choice for women in today's society. The number of women in their late 30s and 40s attempting pregnancy and having babies has increased in

More information

Medications for Inducing Ovulation

Medications for Inducing Ovulation AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE Medications for Inducing Ovulation A Guide for Patients PATIENT INFORMATION SERIES Published by the American Society for Reproductive Medicine under the direction

More information

Medications for Inducing Ovulation

Medications for Inducing Ovulation AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE Medications for Inducing Ovulation A Guide for Patients PATIENT INFORMATION SERIES Published by the American Society for Reproductive Medicine under the direction

More information

CLINICAL PHARMACOLOGY

CLINICAL PHARMACOLOGY FOR SUBCUTANEOUS USE ONLY DESCRIPTION Ganirelix Acetate Injection is a synthetic decapeptide with high antagonistic activity against naturally occurring gonadotropin-releasing hormone (GnRH). Ganirelix

More information

How do fertility drugs work?

How do fertility drugs work? How do fertility drugs work? Under normal circumstances, ovulation occurs once a month when a ripened egg which is ready to be fertilised is released from the ovaries. For couples who are trying to conceive,

More information

Drug Therapy Guidelines: Injectable Fertility Medications

Drug Therapy Guidelines: Injectable Fertility Medications Drug Therapy Guidelines: Injectable Fertility Medications Effective Date: 11/20/07 Committee Review Date: 7/12/00, 5/8/01, 1/15/02, 5/6/0, 12/16/0, 6/8/04, 12/16/05, 2/1/06, 10/15/06, 7/20/07, 11/5/07

More information

Shira Miller, M.D. Los Angeles, CA 310-734-8864 www.shiramillermd.com. The Compounding Pharmacy of Beverly Hills Beverly Hills Public Library

Shira Miller, M.D. Los Angeles, CA 310-734-8864 www.shiramillermd.com. The Compounding Pharmacy of Beverly Hills Beverly Hills Public Library Shira Miller, M.D. Los Angeles, CA 310-734-8864 The Compounding Pharmacy of Beverly Hills Beverly Hills Public Library 2 Outline What is hormone therapy? Why would healthy men and women need to think about

More information

Introduction Ovarian cysts are a very common female condition. An ovarian cyst is a fluid-filled sac on an ovary in the female reproductive system.

Introduction Ovarian cysts are a very common female condition. An ovarian cyst is a fluid-filled sac on an ovary in the female reproductive system. Ovarian Cysts Introduction Ovarian cysts are a very common female condition. An ovarian cyst is a fluid-filled sac on an ovary in the female reproductive system. Most women have ovarian cysts sometime

More information

Lecture 2 Conception and Pregnancy Loss

Lecture 2 Conception and Pregnancy Loss This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this

More information

The cost-effectiveness of IVF in the UK: a comparison of three gonadotrophin treatments Sykes D, Out H J, Palmer S J, van Loon J

The cost-effectiveness of IVF in the UK: a comparison of three gonadotrophin treatments Sykes D, Out H J, Palmer S J, van Loon J The cost-effectiveness of IVF in the UK: a comparison of three gonadotrophin treatments Sykes D, Out H J, Palmer S J, van Loon J Record Status This is a critical abstract of an economic evaluation that

More information

AGE & FERTILITY: Effective Evaluation & Treatment I. LANE WONG, MD, FACOG. www.hopefertilitycenter.com www.hopeivf.com

AGE & FERTILITY: Effective Evaluation & Treatment I. LANE WONG, MD, FACOG. www.hopefertilitycenter.com www.hopeivf.com Page 1 of 6 AGE & FERTILITY: Effective Evaluation & Treatment I. LANE WONG, MD, FACOG. www.hopefertilitycenter.com www.hopeivf.com Age has a profound effect on female fertility. This is common knowledge,

More information

Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome Polycystic Ovarian Syndrome What is Polycystic Ovarian Syndrome? Polycystic ovary syndrome (or PCOS) is a common condition affecting 3 to 5% of women of reproductive age. It is linked with hormonal imbalances,

More information

POLYCYSTIC OVARY SYNDROME

POLYCYSTIC OVARY SYNDROME POLYCYSTIC OVARY SYNDROME Information Leaflet Your Health. Our Priority. Page 2 of 6 What is polycystic ovary syndrome? (PCOS) Polycystic ovary syndrome (PCOS) is the most common hormonal disorder in women

More information

Clinical Study Comparison of IVF Outcomes between Minimal Stimulation and High-Dose Stimulation for Patients with Poor Ovarian Reserve

Clinical Study Comparison of IVF Outcomes between Minimal Stimulation and High-Dose Stimulation for Patients with Poor Ovarian Reserve International Reproductive Medicine, Article ID 581451, 5 pages http://dx.doi.org/10.1155/2014/581451 Clinical Study Comparison of IVF Outcomes between Minimal Stimulation and High-Dose Stimulation for

More information

Fast Track to IVF. Objectives

Fast Track to IVF. Objectives Disclosure statement: Richard H. Reindollar, M.D. has no relevant financial relationships with any manufacturers of pharmaceuticals, laboratory supplies, or medical devices. Fast Track to IVF Richard H.

More information

Emmett F. Branigan, MD,* Antoinette Estes, BS, Kenneth Walker, BS, Jillian Rothgeb, BS. Bellingham IVF and Infertility Center, Bellingham, WA

Emmett F. Branigan, MD,* Antoinette Estes, BS, Kenneth Walker, BS, Jillian Rothgeb, BS. Bellingham IVF and Infertility Center, Bellingham, WA American Journal of Obstetrics and Gynecology (2006) 194, 1696 701 www.ajog.org Thorough sonographic oocyte retrieval during in vitro fertilization produces results similar to ovarian wedge resection in

More information

2. What muscle pulls the testis down into the scrotum during development?

2. What muscle pulls the testis down into the scrotum during development? Anatomy & Physiology Reproductive System Worksheet Male 1. Put the following structures in order from testis to urethra: ductus deferens, rete testis, epididymus, seminiferous tubules 1) 2) 3) 4) 2. What

More information

Ovarian Cysts in Dairy Cattle

Ovarian Cysts in Dairy Cattle AS-451-W Reviewed 2001 Purdue University Cooperative Extension Service West Lafayette, IN 47907 Ovarian Cysts in Dairy Cattle R. D. Allrich, Department of Animal Sciences Purdue University, West Lafayette,

More information

Anatomy of the Male Reproductive System

Anatomy of the Male Reproductive System Anatomy of the Male Reproductive System Anatomy of the Male Reproductive System External genitalia (can be seen on the body surface) penis scrotum Internal genitalia (can t be seen on the body surface)

More information

OVARIAN CYSTS. Types of Ovarian Cysts There are many types of ovarian cysts and these can be categorized into functional and nonfunctional

OVARIAN CYSTS. Types of Ovarian Cysts There are many types of ovarian cysts and these can be categorized into functional and nonfunctional OVARIAN CYSTS Follicular Cyst Ovarian cysts are fluid-filled sacs that form within or on the ovary. The majority of these cysts are functional meaning they usually form during a normal menstrual cycle.

More information

Connecting the Dots: Basal Body Temperature Charting BBT charting: A useful tool to identify your body composition and monitor your progress

Connecting the Dots: Basal Body Temperature Charting BBT charting: A useful tool to identify your body composition and monitor your progress Connecting the Dots: Basal Body Temperature Charting BBT charting: A useful tool to identify your body composition and monitor your progress By Michelle Buchanan, Certified Acupuncturist The History of

More information

What Does Having a FDA Cleared Pregnancy Test Mean?

What Does Having a FDA Cleared Pregnancy Test Mean? What Does Having a FDA Cleared Pregnancy Test Mean? Clinical Trials Transformation Initiative (CTTI) July 15-16, 2013 Denise N. Johnson-Lyles, Ph.D. Toxicology Branch Chief Division of Chemistry and Toxicology

More information

THE WHY, HOW-TO, AND COST OF PROGRAMED AI BREEDING OF DAIRY COWS. J. S. Stevenson

THE WHY, HOW-TO, AND COST OF PROGRAMED AI BREEDING OF DAIRY COWS. J. S. Stevenson Dairy Day 1998 THE WHY, HOW-TO, AND COST OF PROGRAMED AI BREEDING OF DAIRY COWS J. S. Stevenson Summary Management of the estrous cycle is now more practical than it was a decade ago because of our understanding

More information

Accuracy of the Peak Day of Cervical Mucus as a Biological Marker of Fertility

Accuracy of the Peak Day of Cervical Mucus as a Biological Marker of Fertility Marquette University e-publications@marquette Nursing Faculty Research and Publications Nursing, College of 10-1-2002 Accuracy of the Peak Day of Cervical Mucus as a Biological Marker of Fertility Richard

More information

INSULIN RESISTANCE, POLYCYSTIC OVARIAN SYNDROME

INSULIN RESISTANCE, POLYCYSTIC OVARIAN SYNDROME 1 University of Papua New Guinea School of Medicine and Health Sciences Division of Basic Medical Sciences Discipline of Biochemistry and Molecular Biology PBL SEMINAR INSULIN RESISTANCE, POLYCYSTIC OVARIAN

More information

Clearblue Advanced Digital Ovulation Test

Clearblue Advanced Digital Ovulation Test Clearblue Advanced Digital Ovulation Test Identifies a wider fertile window than any other ovulation test for more opportunities to get pregnant naturally Clearblue Professional Series About Clearblue

More information

ANS 3319C Reproductive Physiology and Endocrinology Pregnancy Diagnosis via Rectal Palpation in Cattle and Horses

ANS 3319C Reproductive Physiology and Endocrinology Pregnancy Diagnosis via Rectal Palpation in Cattle and Horses ANS 3319C Reproductive Physiology and Endocrinology Pregnancy Diagnosis via Rectal Palpation in Cattle and Horses Objectives 1) To introduce the management practice of rectal palpation for pregnancy diagnosis

More information

WOMENCARE A Healthy Woman is a Powerful Woman (407) 898-1500. Endometriosis

WOMENCARE A Healthy Woman is a Powerful Woman (407) 898-1500. Endometriosis Endometriosis WOMENCARE A Healthy Woman is a Powerful Woman (407) 898-1500 The lining of the uterus is called the endometrium. Sometimes, endometrial tissue grows elsewhere in the body. When this happens

More information

Lakeview Endocrinology and Diabetes Consultants. 2719 N Halsted St C-1. Chicago IL 60614 P: 773 388 5685 F: 773 388 5687. www.lakeviewendocrinolgy.

Lakeview Endocrinology and Diabetes Consultants. 2719 N Halsted St C-1. Chicago IL 60614 P: 773 388 5685 F: 773 388 5687. www.lakeviewendocrinolgy. Lakeview Endocrinology and Diabetes Consultants 2719 N Halsted St C-1 Chicago IL 60614 P: 773 388 5685 F: 773 388 5687 www.lakeviewendocrinolgy.com Patient information: Early menopause (premature ovarian

More information

The new women s health science of NaProTECHNOLOGY

The new women s health science of NaProTECHNOLOGY Archives of Perinatal Medicine 17(4), 191-198, 2011 ORIGINAL PAPER The new women s health science of NaProTECHNOLOGY THOMAS W. HILGERS Abstract The paper presents the main concepts of NaProTECHNOLOGY.

More information

PUBERTY. Dr. Valérie M. Schwitzgebel. Division of Pediatric Endocrinology and Diabetology Hôpital des Enfants HUG Genève Valerie.Schwitzgebel@hcuge.

PUBERTY. Dr. Valérie M. Schwitzgebel. Division of Pediatric Endocrinology and Diabetology Hôpital des Enfants HUG Genève Valerie.Schwitzgebel@hcuge. PUBERTY Dr. Valérie M. Schwitzgebel Division of Pediatric Endocrinology and Diabetology Hôpital des Enfants HUG Genève Valerie.Schwitzgebel@hcuge.ch V. Schwitzgebel 2004 PHYSIOLOGY of PUBERTY DEFINITION

More information

The IUI procedure Who should consider an IUI IUI success rates IUI cost What to consider if IUI is unsuccessful. The IUI procedure:

The IUI procedure Who should consider an IUI IUI success rates IUI cost What to consider if IUI is unsuccessful. The IUI procedure: A Complete Guide to understanding IUI (intrauterine insemination) and artificial insemination (Eric Daiter, MD Board Certified in Reproductive Endocrinology and Infertility) The IUI procedure Who should

More information

50% Off Cycle 3 $ 9,900 $ 8,700 $ 7,500

50% Off Cycle 3 $ 9,900 $ 8,700 $ 7,500 Specialists In Reproductive Medicine & Surgery, P.A. www.dreamababy.com Fertility@DreamABaby.com Excellence, Experience & Ethics In Vitro Fertilization Price List (2015) We here at Specialists in Reproductive

More information

30% Off Cycle 1. Possible Preliminary Discussions With Contract Negotiations

30% Off Cycle 1. Possible Preliminary Discussions With Contract Negotiations Specialists In Reproductive Medicine & Surgery, P.A. www.dreamababy.com Fertility@DreamABaby.com Excellence, Experience & Ethics Gestational Surrogacy Price List (2015) We here at Specialists in Reproductive

More information

Salivary Progesterone Measurement in Wave I of the Social Life Health & Aging Project

Salivary Progesterone Measurement in Wave I of the Social Life Health & Aging Project Progesterone Salivary Progesterone Measurement in Wave I of the Social Life Health & Aging Project Authors: Bhairavi Nallanathan, University of Chicago, Department of Ob/Gyn Karl Mendoza, BS, University

More information

Ovarian Cyst. Homoeopathy Clinic. Introduction. Types of Ovarian Cysts. Contents. Case Reports. 21 August 2002

Ovarian Cyst. Homoeopathy Clinic. Introduction. Types of Ovarian Cysts. Contents. Case Reports. 21 August 2002 Case Reports 21 August 2002 Ovarian Cyst Homoeopathy Clinic Check Yourself If you have any of the following symptoms call your doctor. Sense of fullness or pressure or a dull ache in the abdomen Pain during

More information

Endocrinology. Values & S.I. Unit Conversion Tables

Endocrinology. Values & S.I. Unit Conversion Tables Endocrinology Expected Values & S.I. Unit Conversion Tables Disclaimer: This data applies to the highly sensitive and specific assay methods developed, validated, and performed solely at Endocrine Sciences.

More information

Research Article Association of ABO Blood Type and Ovarian Stimulation Response in Oocyte Donors

Research Article Association of ABO Blood Type and Ovarian Stimulation Response in Oocyte Donors Cronicon OPEN ACCESS Nigel Pereira 1 *, Anne P Hutchinson 2, Jovana P Lekovich 1, Rony T Elias 1, Zev Rosenwaks 1 and Steven D Spandorfer 1 1 Ronald O Perelman and Claudia Cohen Center for Reproductive

More information

Reproduction Multiple Choice questions

Reproduction Multiple Choice questions Reproduction Multiple Choice questions 1. In mammals that are seasonal breeders, females are receptive only once a year. This is called A) a follicular cycle B) an estrous cycle C) a menstrual cycle D)

More information

Customer Service: Contact your local representative or find country specific contact information on www.abbottdiagnostics.com. Key to symbols used

Customer Service: Contact your local representative or find country specific contact information on www.abbottdiagnostics.com. Key to symbols used FSH system en FSH 7K75 48-6281/R7 B7K750 Read Highlighted Changes Revised November, 2009 Customer Service: Contact your local representative or find country specific contact information on www.abbottdiagnostics.com

More information

Reproductive System & Development: Practice Questions #1

Reproductive System & Development: Practice Questions #1 Reproductive System & Development: Practice Questions #1 1. Which two glands in the diagram produce gametes? A. glands A and B B. glands B and E C. glands C and F D. glands E and F 2. Base your answer

More information

MENOPAUSE WOMAN'S TEST (Assessment of hormone balance)

MENOPAUSE WOMAN'S TEST (Assessment of hormone balance) ATTACHMENT: Useful remarks for patient and doctor, to be associated to the analytical results. Your doctor should interpret this report. Cod. ID: 123456 CCV: 6bf Date: 01/01/2013 Patient: Rossi Mario Rapport

More information

Fertility Preservation in Women with Cancer. Objectives. Patient #1 10/24/2011. The audience will understand: How cancer therapy affects fertility.

Fertility Preservation in Women with Cancer. Objectives. Patient #1 10/24/2011. The audience will understand: How cancer therapy affects fertility. Fertility Preservation in Women with Cancer Leslie R. DeMars Dartmouth-Hitchcock Medical Center Objectives The audience will understand: How cancer therapy affects fertility. Who should be considered for

More information

Enhancement of Conception Rate by EveCare after Ovulation Induction by Clomiphene Citrate followed by Intrauterine Insemination

Enhancement of Conception Rate by EveCare after Ovulation Induction by Clomiphene Citrate followed by Intrauterine Insemination [Advances in Obstetrics & Gynecology (2001): (1), 5, 283-285] Enhancement of Conception Rate by EveCare after Ovulation Induction by Clomiphene Citrate followed by Intrauterine Insemination Arun Kumar,

More information

Infertility: An Overview

Infertility: An Overview AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE Infertility: An Overview A Guide for Patients PATIENT INFORMATION SERIES Published by the American Society for Reproductive Medicine under the direction of the

More information

OVULATION & INTRAUTERINE INSEMINATION (IUI)

OVULATION & INTRAUTERINE INSEMINATION (IUI) OVULATION & This handbook is intended to give you an overview of infertility treatment with IUI and ovulation induction and to better understand the medical circumstances that lead to this treatment option.

More information

Fertility Awareness: An appraisal

Fertility Awareness: An appraisal Fertility Awareness: An appraisal Unless you had a reason to reflect on it, you might think that we understood the basics of human reproduction since the beginning of time. Certainly there had to be some

More information

Comparison of Serum Testosterone and Progesterone Levels in Surgical and Natural. Menopause

Comparison of Serum Testosterone and Progesterone Levels in Surgical and Natural. Menopause Comparison of Serum Testosterone and Progesterone Levels in Surgical and Natural Menopause Raviraj R Naik 1*, Rittu S Chandel 2, Sarita D Dakhure 3, Leela G Abichandani 4 1, 2 Post graduate resident at

More information

Welcome. Thank you for purchasing the OvaCue Fertility Monitor!

Welcome. Thank you for purchasing the OvaCue Fertility Monitor! Owners Manual Welcome Thank you for purchasing the OvaCue Fertility Monitor! Recommended by fertility specialists, this convenient, easy to use fertility monitor provides up to seven days advance notice

More information

PCOS Poly Cystic Ovarian Syndrome and Gardasil Prepared by Leslie Carol Botha April 15, 2011

PCOS Poly Cystic Ovarian Syndrome and Gardasil Prepared by Leslie Carol Botha April 15, 2011 PCOS Poly Cystic Ovarian Syndrome and Gardasil Prepared by Leslie Carol Botha April 15, 2011 Polycystic ovarian syndrome (PCOS) is a disorder characterized by laboratory and/or clinical findings of higher

More information

BUTTE COUNTY PUBLIC HEALTH DEPARTMENT POLICY & PROCEDURE

BUTTE COUNTY PUBLIC HEALTH DEPARTMENT POLICY & PROCEDURE BUTTE COUNTY PUBLIC HEALTH DEPARTMENT POLICY & PROCEDURE SUBJECT: Pregnancy Testing and Counseling Protocol P&P # APPROVED BY: EFFECTIVE DATE: Mark Lundberg MD Health Officer REVISION DATE: 2/20/2010 Phyllis

More information

EFFECT OF INCREASED TESTOSTERONE LEVEL ON WOMAN S FERTILITY

EFFECT OF INCREASED TESTOSTERONE LEVEL ON WOMAN S FERTILITY 1 Nada Polyclinic, Po ega, Croatia 2 School of Medicine, University of Zagreb, Zagreb, Croatia Preliminary Communication Received: April 15, 2004 Accepted: June 16, 2004 EFFECT OF INCREASED TESTOSTERONE

More information

Polycystic Ovarian Syndrome (PCOS)

Polycystic Ovarian Syndrome (PCOS) UW MEDICINE PATIENT EDUCATION Polycystic Ovarian Syndrome (PCOS) Signs, symptoms, and treatments What is PCOS? Polycystic ovarian syndrome (PCOS) is a disorder that affects up to 1 in 10 women of reproductive

More information

, hereby agree to a form of treatment known

, hereby agree to a form of treatment known Patient Consent for Therapy Human In Vitro Fertilization and Embryo Transfer This is to certify that I, as In Vitro Fertilization and Embryo Transfer., hereby agree to a form of treatment known I have

More information

Basics of infertility Student Lecture Dr. A. Vilos, MD, FRCSC, Ass. Professor Department of OB/Gyn, REI Division Western University

Basics of infertility Student Lecture Dr. A. Vilos, MD, FRCSC, Ass. Professor Department of OB/Gyn, REI Division Western University Definitions Basics of infertility Student Lecture Dr. A. Vilos, MD, FRCSC, Ass. Professor Department of OB/Gyn, REI Division Western University Infertility One year of frequent unprotected intercourse

More information

Reproductive System. Anatomy of Male Reproductive System

Reproductive System. Anatomy of Male Reproductive System Function: producing offspring Reproductive System propagation of the species in terms of evolution the only reason all the other systems exist only major system that doesn t work continuously only activated

More information

Female Reproduction: Control of Ovarian Function

Female Reproduction: Control of Ovarian Function 2 Female Reproduction: Control of Ovarian Function F E Robinson and R A Renema Alberta Poultry Research Centre, University of Alberta Edmonton, AB, Canada T6G 2P5 Introduction The control of the release

More information

Clinical Study Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory PCO, or Normal Ovaries

Clinical Study Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory PCO, or Normal Ovaries International Endocrinology Volume 2012, Article ID 492803, 6 pages doi:10.1155/2012/492803 Clinical Study Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory

More information

Rationale for replacing IVIG with Intralipid (IL) for immunological pregnancy loss

Rationale for replacing IVIG with Intralipid (IL) for immunological pregnancy loss Rationale for replacing IVIG with Intralipid (IL) for immunological pregnancy loss Recurrent Pregnancy Loss The reason that an embryo may not implant successfully is either because there is something intrinsically

More information

Female Reproductive System. Unit 8 Lesson 2 Continued

Female Reproductive System. Unit 8 Lesson 2 Continued Female Reproductive System Unit 8 Lesson 2 Continued Female Reproductive System Female Reproductive System Female produce ovum or egg cells. The egg (ovum) cell is the female sex cell. Female Reproductive

More information

Acupuncture Treatment For Infertile Women Undergoing Intracytoplasmic Sperm injection

Acupuncture Treatment For Infertile Women Undergoing Intracytoplasmic Sperm injection Acupuncture Treatment For Infertile Women Undergoing Intracytoplasmic Sperm injection Sandra L. Emmons, MD Phillip Patton, MD Source: Medical Acupuncture, A Journal For Physicians By Physicians Spring

More information

Gonavet Veyx. Depherelin GnRH-Analogue. Application in pigs. Ovulation synchronization for fixed-time insemination

Gonavet Veyx. Depherelin GnRH-Analogue. Application in pigs. Ovulation synchronization for fixed-time insemination Gonavet Veyx GnRH-Analogue Application in pigs Ovulation synchronization for fixed-time insemination Optimization of reproductive performance Gonavet Veyx facilitates control of ovulation in both adult

More information

Outline Fertilization Gametes Germ Cells Meiosis Male Reproductive Tract Spermatogenesis Female Reproductive Tract Oogenesis Menstrual Cycle Hormones

Outline Fertilization Gametes Germ Cells Meiosis Male Reproductive Tract Spermatogenesis Female Reproductive Tract Oogenesis Menstrual Cycle Hormones Outline Fertilization Gametes Germ Cells Meiosis Male Reproductive Tract Spermatogenesis Female Reproductive Tract Oogenesis Menstrual Cycle Hormones Fertilization Gametes Oocyte, Sperm Acrosomal reaction

More information

Sex Hormones In Females And Related Disorders

Sex Hormones In Females And Related Disorders Sex Hormones In Females And Related Disorders (see previous newsletter article for males) Sex Hormone production and measurement in females Follicle Stimulating Hormone () Luteinizing Hormone (), Oestradiol

More information