Suntan Accelerator is a preparation rich in tyrosine and riboflavin that stimulates the biochemical reactions of melanin formation in the skin.

Size: px
Start display at page:

Download "Suntan Accelerator is a preparation rich in tyrosine and riboflavin that stimulates the biochemical reactions of melanin formation in the skin."

Transcription

1 Suntan Accelerator INTRODUCTION Suntan Accelerator is a preparation rich in tyrosine and riboflavin that stimulates the biochemical reactions of melanin formation in the skin. Melanin is a dark pigment which is synthesized in the melanocytes located at the lower layer of the epidermis. This pigment acts as a natural filter of the sun ultraviolet radiation. The formation of melanin is the consequence of the melanocyte reaction against an UV radiation. The quantity of melanin produced, depends on the duration, intensity and frequency of the exposition under ultraviolet light. The biochemical process of the melanin formation is quite complex: the tyrosine amino acid, present in the melanocytes, is oxidised by means of certain redox activators (tyrosinases, riboflavin) and also by the presence of light, oxygen and heat to 3,4-dihydroxyphenylalanine (DOPA). DOPA is also oxidised to dopaquinone and by means of a later oxidation and polymerization, melanin is formed. Melanin has two different varieties: eumelanin, with a dark brown-blackish colour and pheomelanin, with a brownyellowish colour. The first one existing especially in black and brown dark skin people, and the second one in blond or red-haired people. Figure 1. Melanin synthesis pathway. V 03-05/10

2 From the physiologic point of view, the formation of melanin is produced as follows: first of all, tyrosinase is produced at the melanocytes ribosomes; then it passes through the endoplasmic reticulum to the Golgi apparatus, where it is accumulated as small vesicles. Then starts the melanosome formation (very rich in tyrosine), where the tyrosine accumulated in the Golgi apparatus is transferred. Here is where the consecutive biooxidations that lead to the melanin formation take place. By means of vermiform elongations originated in the melanocytes, the melanin synthesized at the melanosomes passes to the keratinocytes, colouring them. The pigment formed by the melanocytes of the lower layer is transferred to the keratinocytes of the epidermis deepest layers, which migrates to the most external layers. This process results in a more or less tanned colour, which at the same time acts as a protection against the UV solar radiation. The skin of white people is poorly pigmented. When it is exposed to the direct action of sun light, UV radiation promotes a great stimulation of melanocytes, with the corresponding melanin increment. However, melanin needs some days to arrive to the most superficial layers of the skin. For these reasons, the pigmentation appears after some days and as in the meantime there is not enough protection some troubles such as redness, irritation and skin burning in the most serious cases appear. To avoid this problem, it is necessary to use preparations including synthetic sun filters, which will replace the initial lack of melanin. On the other side, with a high protection the skin will be tanned very slowly and in some cases very lightly. By adding a preparation which accelerates the formation of melanin in the suntan products with a sun filter, we will obtain a quicker suntan without leaving the skin unprotected. This is the basic principle of the Suntan Accelerator, which will satisfy the essential requirements of solar baths: to obtain the maximum coloration in the minimum time, by causing the minimum damage possible to the skin. CHEMISTRY Suntan Accelerator is presented as a solution which includes the following active components: Tyrosine Riboflavin (Vitamin B) COSMETIC PROPERTIES The formation of melanin in the skin needs the amino acid tyrosine but it also requires the co-operation of light, heat, oxygen and tyrosinase (enzyme). This last enzyme is an oxidase that makes possible the first step of the tyrosine oxidation, helping the final pigment formation. It has been experimentally proved that the single addition of tyrosine in a preparation does not give perceptible results in the skin, since it is necessary the presence of a catalyst of tyrosine oxidation to DOPA. Such oxidation takes place in the skin by means of tyrosinases, but due to its inestability, it is not possible to include it in suntan accelerator preparations. Therefore, instead of tyrosinase the use of riboflavin is more useful, as it also catalyses the tyrosine oxidation process. V 03-05/ ,

3 COSMETIC APPLICATIONS It intensifies the formation of skin melanin. For this reasons, by adding it to the suntan preparation, it helps getting a quicker, intense and lasting tanning. It is important to consider that Suntan Accelerator does not have any sun protecting effect, so it has to be accompanied by a proper sun filter. It helps to obtain a quicker, more intense and long lasting suntan, with the minimum skin damages. EFFICACY TEST 1 Target of the study An study was realized to quantify the level of suntan acquired in the skin after a treatment with a cosmetic product containing only Suntan Accelerator at a concentration of 3.5% (B), Suntan Accelerator plus sun filter (C) or just the cosmetic base (A). The final target was to confirm the effectiveness of the Suntan Accelerator as a suntan activator. Experimental method In this study 15 women were chosen, between 23 and 44 years old, and with a phenotype III or IV (Mediterranean average skin). Three equal zones with a similar skin tone were delimitated in the forearms of the volunteers. Each of the three products (A, B or C) was applied in the corresponding zone for 15 days at the same time of the day, being uniformly extended until it was completely absorbed. Afterwards, the zones were irradiated following the methodology of the Schulze study. Measurements of suntan levels of the volunteers were realized using the Elrephomat model of Zeiss colorimeter. At the beginning of the study the color of these three selected areas was analyzed in all volunteers. Measurements taken during and after the test determined the changes of color produced in each zone compared with the initial values. Results From all of the above, it is possible to deduce the following conclusions: The cream which contained the Suntan Accelerator (B) produced a more intense tan at a faster rate than the cream which did not contain the product (A). The cream which contained the Suntan Accelerator in addition to a solar filter (C) produced a less intense tan at a slower rate than the cream which did not contain the product (A). The differences among the values obtained from the three creams after the application-exposure period were statistically significant. EFFICACY TEST 2 Aim of the study The final aim of the study was to confirm the in vivo effects of the Suntan Accelerator in the skin (compared with a placebo product and a control zone) when applied before receiving solar radiation. Experimental method Ten volunteers were selected from 10 to 60 years old, belonging to the phenotype III or IV according to Fitzpatrick s classification. Three zones of 100 cm 2 were delimitated in their backs to apply the cosmetic product with Suntan Accelerator (at a concentration of 2%), placebo (product without active ingredient) or nothing (control zone). V 03-05/ ,

4 In the treated zones, products were applied once a day during 15 consecutive days (except weekends) and 2 hours before the sun exposure at maximum. The control zone had no product application. Sun exposures took from 6-8 minutes and were received by the volunteers during two weeks except weekends. After obtaining the melanin values using the relation between the absorbed and reflected light by the skin, the curve slopes and suntan increases were calculated for the three zones and compared among them. Results Results of the melanin content are shown in the graphics below. The enhancing effect of the Suntan Accelerator related to the other curves can be clearly seen. The suntan accelerating effect was observed in 90% of volunteers. The small decrease in day 8 and 15 was due to the non exposure of the volunteers during weekends. Melanin index Days Comparing the different treatment groups and realizing a statistical test, it can be said that the skin treated with Suntan Accelerator gets 2.9 times more suntanned than the control zone and also versus a non significant increase of 1.3 obtained by the placebo group. Moreover, the slopes of the zone treated with the active are clearly more pronounced than the other two zones, showing that it also increases the suntan speed of the skin in an important manner. Conclusion Considering the results of the two efficacy tests realized, Suntan Accelerator generates a clear and relevant increase of the suntan induction, causing a melanin augment of 2.9 times versus the non treated zone. Suntan accelerator increases suntan speed and intensity in a clear and visible way. RECOMMENDED DOSE The recommended dose is between 2.0% and 3.5%. V 03-05/ ,

5 BIBLIOGRAPHY Février, F., Bobin, M.F., Lafforgue, C., Martín, M.C. Advances in microemulsions and transepidermal penetration of tyrosine. STP Pharm Sci 1:60, 1991; 1(1): (ref.716). Fitzpatrick, T.B., Szabó, G., Wick, M.M. Biochemistry and Physiology of melanin pigmentation. In: Goldsmith LA (ed.). Physiology, Biochemistry and Molecular Physiology of the Skin. Oxford University Press, New York, pp , 1983 (ref. 2308). Guglielmini, G. Substantiating claims for a tanning magnifier. C&T, 2004; 119(6): (ref.6651). Meredith, P., Sarna, T. The physical and chemical properties of eumelanin. Pigment Cell Res., 2006; 19(6): (ref. 8839). Prota, G. Melanins and Melanogenesis. C&T 1996; 111: (ref. 1585). Riva, A., Prieto, M. Acelerador del bronceado. Determinación de la Eficacia por Colorimetria. Industria farmaceutica, 1989; 4 (6): (ref. 4262). Riley, P.A. The mechanism of skin pigmentation production. J. Soc. Cosmet. Chem. 1977; 28: (ref. 2303). Sánchez-Ferrer, A., Rodríguez-López, J.N, García-Canovas, F., García-Carmona, F. Tyrosinase: a comprehensive review of its mechanism. Biochim Biophys Acta. 1995; 1247(1):1-11 (ref. 4174). Stanzi, K., Thiry, D., Röding, J., Zastrow, L. Development and Testing of a New Suntan Accelerator. SÖFW-Journal, 1992; 118: (ref.717). V 03-05/ ,

The mechanism of skin pigmentation

The mechanism of skin pigmentation The mechanism of skin pigmentation UV light stimulates melanin production by human epidermal melanocytes Melanocyte located at the basal cell layer of the epidermis forms long, finger-like dendrites contains

More information

MelanoBronze Natural Tanning Activator

MelanoBronze Natural Tanning Activator MelanoBronze Natural Tanning Activator MelanoBronze Acetyl tyrosine Substrate for tyrosinase enzyme in melanin synthesis Vitex agnus-castus extract Induction of melanin synthesis in melanocytes MelanoBronze

More information

BASIC CONCEPTS OF HAIR PHYSIOLOGY AND COSMETIC HAIR DYES

BASIC CONCEPTS OF HAIR PHYSIOLOGY AND COSMETIC HAIR DYES Staple here TECHNICAL MANUAL BASIC CONCEPTS OF HAIR PHYSIOLOGY AND COSMETIC HAIR DYES COVER PAGE MACRO-STRUCTURE OF THE HAIR The hair is formed by the shaft and the piliferous bulb. The visible part of

More information

NU SKIN TRI-PHASIC WHITE Activation Synthesis Expression

NU SKIN TRI-PHASIC WHITE Activation Synthesis Expression NU SKIN TRI-PHASIC WHITE Activation Synthesis Expression Is your inner beauty hidden behind a barrier of dull, discolored skin? As skin is affected by many different factors, including sun, stress, irritation,

More information

Delentigo The age spot solution

Delentigo The age spot solution The age spot solution The age spot solution Erasing Age Spots and Equalizing the Skin Tone Delentigo targets and lightens age spots by combining two active substances incorporated into separate liposomes:

More information

HUMAN SKIN COLOR: EVIDENCE FOR SELECTION

HUMAN SKIN COLOR: EVIDENCE FOR SELECTION OVERVIEW HUMAN SKIN COLOR: EVIDENCE FOR SELECTION This activity supports the viewing of the short film The Biology of Skin Color. Students watch the film in segments and use real data to propose hypotheses,

More information

SIHHHDS303A. Hair colour. Skilling people for the industry

SIHHHDS303A. Hair colour. Skilling people for the industry SIHHHDS303A Hair colour Skilling people for the industry SIHHHDS303A Hair colour Skilling people for the industry Hair colour all theory and preparation for real skills transfer from mannequin activities

More information

CHRONOCYCLIN. Cosmetic application. day and night skin care

CHRONOCYCLIN. Cosmetic application. day and night skin care Cosmetic application day and night skin care Temporary or long-term cutaneous damages overworked, tired, lack of sun exposure, jet lag anti-aging benefits Skin awakening Stimulation of cutaneous natural

More information

TO INVESTIGATE THE PROTECTION OF SUNCREAMS AGAINST UV RAYS

TO INVESTIGATE THE PROTECTION OF SUNCREAMS AGAINST UV RAYS TO INVESTIGATE THE PROTECTION OF SUNCREAMS AGAINST UV RAYS Aim: Our aim for this project is to collect data on the effectiveness of different sunscreens against UVA and UVB light, a) In natural sunlight

More information

A Vegetan Premium: The First Cosmetic Active both Self-tanner and Antioxidant

A Vegetan Premium: The First Cosmetic Active both Self-tanner and Antioxidant A : The First Cosmetic Active both Self-tanner and Antioxidant Authors: Celina Rocquet, Romain Reynaud, Soliance, France Abstract is an active ingredient that is a synergistic combination of Dihydroxyacetone

More information

Porcelain Allure. The Secret of Radiance

Porcelain Allure. The Secret of Radiance Porcelain Allure The Secret of Radiance Cultural Heritage SIMBOL OF ROYALTY: from Mediterrean ancient cultures to the Chinese Han dynasty fair skin has always been an obsession. The first form of make-up

More information

Aging: Brown Spots/Age Spots/Hyperpigmentation (by Andrew Scoular)

Aging: Brown Spots/Age Spots/Hyperpigmentation (by Andrew Scoular) Aging: Brown Spots/Age Spots/Hyperpigmentation (by Andrew Scoular) When we are young we see brown spots on the skin as a sign of another persons age. When we turn into that older other person, we want

More information

The skin. The skin is the external layer of the body Variable thickness (frictional forces) Several functions as :

The skin. The skin is the external layer of the body Variable thickness (frictional forces) Several functions as : The skin The skin is the external layer of the body Variable thickness (frictional forces) Several functions as : Protection (mecanical, physical and chemical) Metabolism (production of vitamin D) Thermoregulation

More information

UV Analysis of Sunscreens

UV Analysis of Sunscreens UV Analysis of Sunscreens Texas A&M University Organic Lab 238 The Electromagnetic Spectrum The UV region is the range of frequencies just higher than those for visible light UV-Vis energies correspond

More information

EXPERIMENT 3 Potato Polyphenol Oxidase (I) 1 BACKGROUND

EXPERIMENT 3 Potato Polyphenol Oxidase (I) 1 BACKGROUND EXPERIMENT 3 Potato Polyphenol Oxidase (I) 1 BACKGROUND Polyphenol oxidase, also known as tyrosinase (EC 1.14.18.1) is an enzyme responsible for one of the steps in the conversion of tyrosine into melanine,

More information

Efficacy Testing of Skin Whitening Products

Efficacy Testing of Skin Whitening Products Efficacy Testing of Skin Whitening Products John Staton Dermatest Pty Ltd Published in Personal Care Asia 2009 Skin Whitening Lightening Brightening? These terms are used interchangeably (1) when describing

More information

SKIN CANCER AND TANNING 101. Introduction. There are more than one hundred types of cancer. All the kinds of cancer begin in our cells.

SKIN CANCER AND TANNING 101. Introduction. There are more than one hundred types of cancer. All the kinds of cancer begin in our cells. Introduction There are more than one hundred types of cancer. All the kinds of cancer begin in our cells. Normal cells grow and multiply and then die. Cancer cells grow and multiply and keep growing and

More information

Explaining Ellipse I 2 PL

Explaining Ellipse I 2 PL Explaining Ellipse I 2 PL CLINICALLY PROVEN SAFE AND EFFECTIVE Ellipse I 2 PL stands for Ellipse secondgeneration Intense Pulsed Light The Ellipse I 2 PL system is used for the treatment of a wide range

More information

Smooth Lightening White rose. The origins of a radiant complexion

Smooth Lightening White rose. The origins of a radiant complexion Smooth Lightening White rose The origins of a radiant complexion NAOLYS ACTIVE CELLS Smooth Lightening White rose The origins of a radiant complexion A STORY The white rose Rosa alba, Rosaceae The elegance

More information

Carbon Balance, Respiration and Environment. K. Raja Reddy

Carbon Balance, Respiration and Environment. K. Raja Reddy Carbon Balance, Respiration and Environment K. Raja Reddy Krreddy@pss.msstate.edu Carbon Balance, Respiration and Environment Goals and learning objectives are to: Understand the respiration costs associated

More information

DETERMINING WHICH COLOR UV BEAD CHANGES COLORS THE FASTEST

DETERMINING WHICH COLOR UV BEAD CHANGES COLORS THE FASTEST DETERMINING WHICH COLOR UV BEAD CHANGES COLORS THE FASTEST Helen C Cary Academy ABSTRACT The purpose of this experiment was to determine which color UV bead changes colors the fastest. The bead colors

More information

FAQs FREQUENTLY ASKED QUESTIONS FORWARD BEAUTY

FAQs FREQUENTLY ASKED QUESTIONS FORWARD BEAUTY FAQs FREQUENTLY ASKED QUESTIONS FORWARD BEAUTY GENERAL PRODUCT INFORMATION 1. What is the purpose of the ARTISTRY IDEAL RADIANCE skincare line? The ARTISTRY IDEAL RADIANCE Collection with 3D Brightening

More information

Self-tanning Based on Stimulation of Melanin Biosynthesis

Self-tanning Based on Stimulation of Melanin Biosynthesis Self-tanning Based on Stimulation of Melanin Biosynthesis Daniel Schmid, Esther Belser and Fred Zülli Mibelle AG Biochemistry, Buchs, Switzerland Key words: self-tanning, melanin, chaste tree, acetyl tyrosine,

More information

Cat Coat Color, Pattern and Genetics

Cat Coat Color, Pattern and Genetics Sonja Prohaska Computational EvoDevo University of Leipzig May 18, 2015 Cat Coat Color, Pattern and Genetics How Hair Gets Color melanoblasts derive from neural crest dorso-ventral migration (back to belly)

More information

LAFHAB GB2. Change men's colour. Session 4 of 6. Level 2 Barbering. Learner Name Date session started Date session finished

LAFHAB GB2. Change men's colour. Session 4 of 6. Level 2 Barbering. Learner Name Date session started Date session finished GB2 Change men's colour Learner Name Date session started Date session finished Session 4 of 6 Level 2 Barbering GB2.4.1a Colour and Light When looking at an object or at the colour of hair, what you are

More information

Vantage Pro2, Vantage VUE, Vantage Pro, and Health EnviroMonitor Systems

Vantage Pro2, Vantage VUE, Vantage Pro, and Health EnviroMonitor Systems INTERPRETING UV READINGS Application Note 6 Vantage Pro2, Vantage VUE, Vantage Pro, and Health EnviroMonitor Systems Introduction Ultraviolet (UV) radiation can cause health damage in many ways: to the

More information

A N U L T I M A T E B R A N D F O R B E A U T Y

A N U L T I M A T E B R A N D F O R B E A U T Y P RODUCT L I N E A N U L T I M A T E B R A N D F O R B E A U T Y info@parley.pk, info@khyberchemical.com Proven Results in 4 weeks. Skin softer more radiant and eventoned. Dark spots visibly reduced Gives

More information

Brownallyear.com. Your spray tanning bible. Tanning Bible. How to get the best out of your spray tans Look Great, Feel Great, Be Great

Brownallyear.com. Your spray tanning bible. Tanning Bible. How to get the best out of your spray tans Look Great, Feel Great, Be Great Brownallyear.com Tanning Bible Your spray tanning bible How to get the best out of your spray tans Look Great, Feel Great, Be Great Title page All you ever need to know about spray tanning *The history

More information

Skin Science: The Use of

Skin Science: The Use of Skin Science: The Use of Genomics Tools in Skin Care Genemarkers LLC Anna Langerveld, PhD anna@genemarkersllc.com www.genemarkersllc.com Cosmeceuticals Summit March 9-11, 2009 Orlando, FL What is Skin

More information

May Is National Melanoma/Skin Cancer Detection and Prevention Month

May Is National Melanoma/Skin Cancer Detection and Prevention Month May Is National Melanoma/Skin Cancer Detection and Prevention Month What is Melanoma? Melanoma is a type of skin cancer. It begins in the cells of the skin called melanocytes. To understand melanoma, it

More information

Malignant Melanoma Early Stage. A guide for patients

Malignant Melanoma Early Stage. A guide for patients This melanoma patient brochure is designed to help educate melanoma patients and their caregivers. It was developed under the guidance of Dr. Michael Smylie, Professor, Department of Oncology, University

More information

EXPLANATION OF WEATHER ELEMENTS AND VARIABLES FOR THE DAVIS VANTAGE PRO 2 MIDSTREAM WEATHER STATION

EXPLANATION OF WEATHER ELEMENTS AND VARIABLES FOR THE DAVIS VANTAGE PRO 2 MIDSTREAM WEATHER STATION EXPLANATION OF WEATHER ELEMENTS AND VARIABLES FOR THE DAVIS VANTAGE PRO 2 MIDSTREAM WEATHER STATION The Weather Envoy consists of two parts: the Davis Vantage Pro 2 Integrated Sensor Suite (ISS) and the

More information

E TA TECHNICAL REPORT. Exposure procedure for artificial weathering. TR 010 Edition May 2004 EUROPEAN ORGANISATION FOR TECHNICAL APPROVALS

E TA TECHNICAL REPORT. Exposure procedure for artificial weathering. TR 010 Edition May 2004 EUROPEAN ORGANISATION FOR TECHNICAL APPROVALS E TA TECHNICAL REPORT Exposure procedure for artificial weathering TR 010 Edition May 004 EUROPEAN ORGANISATION FOR TECHNICAL APPROVALS Exposure procedure for artificial weathering Edition May 004 1 Scope

More information

LEUPHASYL A NEW PENTAPEPTIDE FOR EXPRESSION WRINKLES CODE: PD080. Date: June 2005 Revision: 1 A GMP PEPTIDE FOR COSMETIC APPLICATIONS

LEUPHASYL A NEW PENTAPEPTIDE FOR EXPRESSION WRINKLES CODE: PD080. Date: June 2005 Revision: 1 A GMP PEPTIDE FOR COSMETIC APPLICATIONS Polígon Industrial Camí Ral C/Isaac Peral, 17 08850 Gavá Barcelona - Spain Telf. +34 93 638 80 00 fax. +34 93 638 93 93 Internet: www.lipotec.com e-mail. commercial@lipotec.com abcde LEUPHASYL A NEW PENTAPEPTIDE

More information

Narrowband Ultraviolet Radiation (UVB) (phototherapy)

Narrowband Ultraviolet Radiation (UVB) (phototherapy) Narrowband Ultraviolet Radiation (UVB) (phototherapy) Therapy Services Physiotherapy Department 01625 661481 Leaflet Ref: 11195 Published: 06/15 Review: 06/18 Page 1 Introduction Your doctor or consultant

More information

TANNING: FREQUENTLY ASKED QUESTIONS

TANNING: FREQUENTLY ASKED QUESTIONS TANNING: FREQUENTLY ASKED QUESTIONS General Statistics: An estimated 30 million North Americans 65% to 70% of them women turned to tanning salons in 2006 as a controlled alternative to outdoor tanning.

More information

Unit 1 Lesson 3 Cell Structure and Function. Copyright Houghton Mifflin Harcourt Publishing Company

Unit 1 Lesson 3 Cell Structure and Function. Copyright Houghton Mifflin Harcourt Publishing Company Being Eu-nique What are the characteristics of eukaryotic cells? Eukaryotic cells differ from each other depending on their structure and function. Structure is the arrangement of parts. Function is the

More information

Bio Europe Munich. November 4, 2015 TSX-V: SBM

Bio Europe Munich. November 4, 2015 TSX-V: SBM Bio Europe Munich November 4, 2015 TM Sirona s Fluorination Chemistry Technology The Solution to Unstable Carbohydrate Molecules Carbohydrate molecules are unstable by nature Our technology stabilizes

More information

Human Biology Book Ch. 3.3

Human Biology Book Ch. 3.3 Human Biology Book Ch. 3.3 Skin performs important functions. Just as an apple's skin protects the fruit inside, your skin protects the rest of your body. Made up of flat sheets of cells, your skin protects

More information

Chemical Waves in the Belousov-Zhabotinsky Reaction: Determining a Rate Constant with a Ruler

Chemical Waves in the Belousov-Zhabotinsky Reaction: Determining a Rate Constant with a Ruler Chemical Waves in the Belousov-Zhabotinsky Reaction: Determining a Rate Constant with a Ruler John A. Pojman Department of Chemistry and Biochemistry, The University of Southern Mississippi, Hattiesburg,

More information

Nature s Chemistry Fragrances and Skin Care

Nature s Chemistry Fragrances and Skin Care Kirkcaldy High School CfE Higher Chemistry Nature s Chemistry Fragrances and Skin Care Page 1 of 14 No. Learning Outcome Understanding? 1 Essential oils are concentrated extracts of the volatile, non-water

More information

Nature s Chemistry Fragrances and Skin Care

Nature s Chemistry Fragrances and Skin Care Cathkin High School CfE Higher Chemistry Nature s Chemistry Fragrances and Skin Care Page 1 of 14 No. Learning Outcome Understanding? 1 Essential oils are concentrated extracts of the volatile, non-water

More information

Scientifically and Clinically Proven Anti-Aging Skin Serum

Scientifically and Clinically Proven Anti-Aging Skin Serum Scientifically and Clinically Proven Anti-Aging Skin Serum This white paper provides detailed information on the efficacy and scientific evidence of topically applied skin care serums, with an emphasis

More information

raan uv systems INFRARED TERM 2000 cabins with Philips VITAE lamps

raan uv systems INFRARED TERM 2000 cabins with Philips VITAE lamps INFRARED TERM 2000 cabins with Philips VITAE lamps Until lately, there were just Infra Red cabins using the medium-wave (IR-B) and long-wave (IR-C) lamps, so-called: not shining or black available in retail.

More information

THE COLIPA SPF TEST METHOD THE DEVIL IS IN THE DETAIL. Mike Brown

THE COLIPA SPF TEST METHOD THE DEVIL IS IN THE DETAIL. Mike Brown THE COLIPA SPF TEST METHOD THE DEVIL IS IN THE DETAIL Mike Brown Suncare Scientific Adviser THE BOOTS COMPANY PLC Nottingham (UK) SCC Florida Chapter Sunscreen Symposium April 27th 2001 Contents INTRODUCTION

More information

Stabilized oil-soluble. soluble vitamin C derivative. Vitamin C Whitening Collagen Anti-oxidant DNA UV Stable Synthesis Protection Protection

Stabilized oil-soluble. soluble vitamin C derivative. Vitamin C Whitening Collagen Anti-oxidant DNA UV Stable Synthesis Protection Protection Stabilized oil-soluble soluble vitamin C derivative Vitamin C Whitening Collagen Anti-oxidant DNA UV Stable Synthesis Protection Protection Oil-Soluble Vitamin C Derivative RO OR CHCH 2 OR O O H OR INCI

More information

Chemical reaction (slow): Enzyme-catalyzed reaction (much faster):

Chemical reaction (slow): Enzyme-catalyzed reaction (much faster): 1 Enzymes Introduction Enzymes are Biological Catalysts Recall that a catalyst is an agent which speeds up a chemical reaction without actually being consumed or changed by the reaction. Enzymes are proteins

More information

Treating your skin condition with narrowband ultraviolet B radiation (NB-UVB)

Treating your skin condition with narrowband ultraviolet B radiation (NB-UVB) Treating your skin condition with narrowband ultraviolet B radiation (NB-UVB) Your doctor has referred you to the Dowling Day Treatment Centre for a course of narrow band ultraviolet treatment for your

More information

Index. An even skin tone makes you glow! 4. How are pigmented patches formed? 5

Index. An even skin tone makes you glow! 4. How are pigmented patches formed? 5 Bl Blanchesse Index An even skin tone makes you glow! 4 How are pigmented patches formed? 5 Types of pigmented patches 6 Pigmented patches (age spots) 6 Birthmarks 6 Melasma (pregnancy mask) 7 Dark pigmented

More information

New Methods for Guidance of Light-Based Treatments Using Objective Melanin Measurements

New Methods for Guidance of Light-Based Treatments Using Objective Melanin Measurements New Methods for Guidance of Light-Based Treatments Using Objective Melanin Measurements Sean Doherty, MD, 1 Richard Cohen, PhD, 2 Felicia Whitney, RN, 2 Oksana Bradley, MD, 2 (Ukraine) Brooke Seckel, MD

More information

LAB TOPIC 4: ENZYMES. Enzyme catalyzed reactions can be expressed in the following way:

LAB TOPIC 4: ENZYMES. Enzyme catalyzed reactions can be expressed in the following way: LAB TOPIC 4: ENZYMES Objectives Define enzyme and describe the activity of enzymes in cells. Discuss the effects of varying enzyme concentrations on the rate of enzyme activity. Discuss the effects of

More information

Two main classes: Epithelial Connective (synovial) Epithelial. Cutaneous Mucous Serous

Two main classes: Epithelial Connective (synovial) Epithelial. Cutaneous Mucous Serous Two main classes: Epithelial Connective (synovial) Epithelial Cutaneous Mucous Serous Epithelial Membranes = sheet of epithelia + connective tissue base 1. Cutaneous membrane: outer skin layer (stratified

More information

5. The chart below indicates the elements contained in four different molecules and the number of atoms of each element in those molecules.

5. The chart below indicates the elements contained in four different molecules and the number of atoms of each element in those molecules. 1. In the diagram below, which substance belongs in area Z? 5. The chart below indicates the elements contained in four different molecules and the number of atoms of each element in those molecules. A)

More information

Hyperpigmentation. Hype. The

Hyperpigmentation. Hype. The The Hyperpigmentation By Bella Schneider Hyperpigmentation is the most common skin disorder seen at skin care facilities, and one that every client wants corrected. It effects both menand women and is

More information

CHEMICAL KINETICS. The following methods can be used to increase the rate of a reaction.

CHEMICAL KINETICS. The following methods can be used to increase the rate of a reaction. Kinetics F325 1 CHEMICAL KINETICS Reminder The following methods can be used to increase the rate of a reaction. increase surface area increase temperature add a catalyst use a light source (certain reactions

More information

1. 4. 1: Biochemistry of macromolecules and metabolic pathways

1. 4. 1: Biochemistry of macromolecules and metabolic pathways 1. 4 Investigating enzymes Many factors affect the activity of enzymes and it is very easy to investigate these factors using common enzymes. Enzymes work at their optimum temperature and ph. Any changes

More information

Compendium Basic knowledge SKIN. Structure Functions Size

Compendium Basic knowledge SKIN. Structure Functions Size Compendium Basic knowledge SKIN Structure Functions Size Structure The skin (dermatologically called cutis ) is an organ which is built up in layers. Structure of the Skin The skin consists of three basic

More information

In Vivo Methods to Prove Anti-Photoaging and Anti-Pollution Efficacy of Cosmetic Products

In Vivo Methods to Prove Anti-Photoaging and Anti-Pollution Efficacy of Cosmetic Products In Vivo Methods to Prove Anti-Photoaging and Anti-Pollution Efficacy of Cosmetic Products Stephan Bielfeldt Anti-Aging Summit 7.- 8. June 2016 Agenda Photoaging: The clinical picture What is the cause

More information

STANDARD CONDITIONS ELECTROLYSIS / ELECTRICAL EPILATION

STANDARD CONDITIONS ELECTROLYSIS / ELECTRICAL EPILATION Approved by Full Council on the 28 th June 2010 1.0 Definitions Electrolysis or Electrical Epilation STANDARD CONDITIONS ELECTROLYSIS / ELECTRICAL EPILATION For the purposes of these standard conditions,

More information

1. Its concentration in the atmosphere 2. Its ability to absorb IR radiation 3. Its lifetime in the atmosphere

1. Its concentration in the atmosphere 2. Its ability to absorb IR radiation 3. Its lifetime in the atmosphere The greenhouse effect - global warming: Radiation from the sun reaches the planet. The radiation is absorbed by the Earth and re emitted as IR radiation. Most of this IR radiation goes back into space

More information

REVERSE PRODUCT TRAINING This advanced training establishes the link between the conditions of dull skin, dark marks, and sun damage.

REVERSE PRODUCT TRAINING This advanced training establishes the link between the conditions of dull skin, dark marks, and sun damage. REVERSE REGIMEN REVERSE PRODUCT TRAINING This advanced training establishes the link between the conditions of dull skin, dark marks, and sun damage. Nine years ago Dr. Rodan and Dr. Fields clinically

More information

REVERSE. Regimen for the Appearance of Brown Spots, Dullness and Discoloration

REVERSE. Regimen for the Appearance of Brown Spots, Dullness and Discoloration REVERSE Regimen for the Appearance of Brown Spots, Dullness and Discoloration It s not what you see, it s what you don t see. It s estimated that as much as 80% of skin s aged appearance is caused by the

More information

Melanoma. Information for you, your family, whänau and friends. Published by the New Zealand Guidelines Group

Melanoma. Information for you, your family, whänau and friends. Published by the New Zealand Guidelines Group Melanoma Information for you, your family, whänau and friends Published by the New Zealand Guidelines Group Contents About melanoma 1 What is melanoma? 2 What causes melanoma? 3 How can melanoma be prevented?

More information

PIONNIÈRE XMF WHITE. Skin Translucency Cream OVERALL ANTI-AGING: SKIN TONE DARK SPOTS WRINKLES

PIONNIÈRE XMF WHITE. Skin Translucency Cream OVERALL ANTI-AGING: SKIN TONE DARK SPOTS WRINKLES PIONNIÈRE XMF WHITE Skin Translucency Cream OVERALL ANTI-AGING: SKIN TONE DARK SPOTS WRINKLES PIONNIÈRE XMF WHITE FREES THE SKIN FROM ALL ITS FLAWS: DARK SPOTS: WOMEN'S NEW CONCERN AFTER WRINKLES 62% of

More information

1. Which of the following correctly organizes genetic material from the broadest category to the most specific category?

1. Which of the following correctly organizes genetic material from the broadest category to the most specific category? DNA and Genetics 1. Which of the following correctly organizes genetic material from the broadest category to the most specific category? A. genome chromosome gene DNA molecule B. genome chromosome DNA

More information

The Dangers of Sunless Tanning

The Dangers of Sunless Tanning The Dangers of Sunless Tanning Over the past decade the media has pushed the idea that the sun is dangerous and harmful so hard that the majority of people now believe this to be fact. We, as a society,

More information

Lactobionic Acid Anti-Aging Mechanisms: Antioxidant Activity, MMP Inhibition, and Reduction of Melanogenesis

Lactobionic Acid Anti-Aging Mechanisms: Antioxidant Activity, MMP Inhibition, and Reduction of Melanogenesis INTRODUCTION Lactobionic acid, 4-O-β-galactopyranosyl-D-gluconic acid, is a polyhydroxy bionic acid that was previously reported to provide significant anti-aging and protective effects to human skin.

More information

How Does the UNBLEMISH Regimen Work?

How Does the UNBLEMISH Regimen Work? How Does the UNBLEMISH Regimen Work? Based on Multi-Med Therapy, UNBLEMISH is a complete skincare system that combines cosmetic and OTC ingredients that penetrate pores to eliminate acne blemishes before

More information

ATS NO-FOOD SUNSCREEN PRODUCTS: METHOD FOR THE IN VITRO DETERMINATION OF PHOTOSTABILITY OF UV FILTERS

ATS NO-FOOD SUNSCREEN PRODUCTS: METHOD FOR THE IN VITRO DETERMINATION OF PHOTOSTABILITY OF UV FILTERS Informative document nr. 147E Issue date: 18/09/2007 review nr 0 ATS NO-FOOD SUNSCREEN PRODUCTS: METHOD FOR THE IN VITRO DETERMINATION OF PHOTOSTABILITY OF UV FILTERS Contact person: dr.ssa Chiara Chiaratti

More information

Basic Scientific Principles that All Students Should Know Upon Entering Medical and Dental School at McGill

Basic Scientific Principles that All Students Should Know Upon Entering Medical and Dental School at McGill Fundamentals of Medicine and Dentistry Basic Scientific Principles that All Students Should Know Upon Entering Medical and Dental School at McGill Students entering medical and dental training come from

More information

Cells and Their Organelles

Cells and Their Organelles Cells and Their Organelles The cell is the basic unit of life. The following is a glossary of animal cell terms. All cells are surrounded by a cell membrane. The cell membrane is semi-permeable, allowing

More information

Frequently Asked Questions

Frequently Asked Questions Frequently Asked Questions 1. Q. How do self tanners work? A. The principle tanning agent used in all self-tanning formulas is dihydroxyacetone (DHA). This ingredient does not produce a "real tan" by increasing

More information

EFFECT OF CHLORINE ON HUMAN HAIR

EFFECT OF CHLORINE ON HUMAN HAIR EFFECT OF CHLORINE ON HUMAN HAIR by Marianne Suwalski Background, Purpose and Hypothesis I have been swimming for many years, without ever wearing a swim cap, and have always had brittle and dull hair.

More information

Safety Safety glasses or goggles must be worn in the laboratory at all times.

Safety Safety glasses or goggles must be worn in the laboratory at all times. APPLE BROWNING: A STUDY OF OXIDATION OF FOODS 2005, 1997 by David A. Katz. All rights reserved. Reproduction permitted for education use provided original copyright is included. You are preparing for a

More information

TiO 2. : A New Kind of Water Treatment. Registered charity number 207890

TiO 2. : A New Kind of Water Treatment.  Registered charity number 207890 TiO 2 : A New Kind of Water Treatment www.rsc.org/learn-chemistry Registered charity number 207890 3: A new kind of water treatment What is solar disinfection with titanium dioxide and how does it work?

More information

DEFENCE HYDRA5. The quintessence of hydration

DEFENCE HYDRA5. The quintessence of hydration Provide the consumer, even with sensitive skin, with well tolerated, safe, effective products having a fair quality/price ratio. * Also residual nickel content can lead, especially in allergyprone subjects,

More information

Skin Cancer Frequently Asked Questions

Skin Cancer Frequently Asked Questions What happens at the clinic? On arrival you will fill out a short questionnaire which includes previous skin cancer diagnosis and treatment, family history and other relevant medical history. The doctor

More information

Manufacturing dye- sensitized solar cells

Manufacturing dye- sensitized solar cells Manufacturing dye- sensitized solar cells By Kasra Amini (year 3 summer student, UCL) Introduction: Semiconductor materials are used greatly in modern electronics, such as in: radios, telephones, computers,

More information

about Why You Should Know Melanoma

about Why You Should Know Melanoma about Why You Should Know Melanoma Why You Should Know about Melanoma Each year, more than 3 million Americans are diagnosed with skin cancer. This is the most common form of cancer. Of these, more than

More information

Cell Specialization. Examples of Specialized Cells. Sperm Cell.

Cell Specialization. Examples of Specialized Cells. Sperm Cell. Cell Specialization All organisms are composed of cells. Unicellular organisms are composed of a single cell. Multicellular organisms are composed of many specialized cells. Specialized cells differ in

More information

SUPPLEMENTARY TOPIC 3 ENERGY AND CHEMICAL REACTIONS

SUPPLEMENTARY TOPIC 3 ENERGY AND CHEMICAL REACTIONS SUPPLEMENTARY TOPIC 3 ENERGY AND CHEMICAL REACTIONS Rearranging atoms. In a chemical reaction, bonds between atoms in one or more molecules (reactants) break and new bonds are formed with other atoms to

More information

A Look at Accelerated Photostability Testing for Packaged Food and Drinks

A Look at Accelerated Photostability Testing for Packaged Food and Drinks A Look at Accelerated Photostability Testing for Packaged Food and Drinks By Dr. Oliver Rahäuser and Dr. Artur Schönlein Atlas Material Testing Technology GmbH Vogelsbergstr. 22, 63589 Linsengericht-Altenhaßlau,

More information

Cell Structure & Function!

Cell Structure & Function! Cell Structure & Function! Chapter 3! The most exciting phrase to hear in science, the one that heralds new discoveries, is not 'Eureka!' but 'That's funny.! -- Isaac Asimov Animal Cell Plant Cell Cell

More information

Compendium. UV Protection at Work. Basics Vulnerable Persons Protection Possibilities UV Protection Products In General Legislation

Compendium. UV Protection at Work. Basics Vulnerable Persons Protection Possibilities UV Protection Products In General Legislation Compendium Protection at Work Basics Vulnerable Persons Protection Possibilities Protection Products In General Legislation Basics Photodamage to the Skin Ultraviolet radiation (= radiation) from a natural

More information

ATP. Division Avenue High School Regents Biology. Types of cells. Cells & Cell Organelles. Why study cells? Cell size comparison

ATP. Division Avenue High School Regents Biology. Types of cells. Cells & Cell Organelles. Why study cells? Cell size comparison Types of cells bacteria cells Prokaryote - no organelles Cells & Cell Organelles The Building Blocks of Life AP Biology 2008-2009 animal cells Eukaryotes - organelles Cell size comparison Animal cell Bacterial

More information

According to the Fitzpatrick Scale. African & Asian skin. african & asian skin 25 Colour spectrum

According to the Fitzpatrick Scale. African & Asian skin. african & asian skin 25 Colour spectrum 25 Colour spectrum African & Asian skin All human skin has the same basic anatomical structure epidermis, dermis and subcutaneous layer but each racial skin type displays its own particular characteristics.

More information

Topic 3: Nutrition, Photosynthesis, and Respiration

Topic 3: Nutrition, Photosynthesis, and Respiration 1. Base your answer to the following question on the chemical reaction represented below and on your knowledge of biology. If this reaction takes place in an organism that requires sunlight to produce

More information

CELL/ PHOTOSYNTHESIS/ CELLULAR RESPIRATION Test 2011 ANSWER 250 POINTS ANY WAY IN WHICH YOU WANT

CELL/ PHOTOSYNTHESIS/ CELLULAR RESPIRATION Test 2011 ANSWER 250 POINTS ANY WAY IN WHICH YOU WANT CELL/ PHOTOSYNTHESIS/ CELLULAR RESPIRATION Test 2011 ANSWER 250 POINTS ANY WAY IN WHICH YOU WANT Completion: complete each statement. (1 point each) 1. All cells arise from. 2. The basic unit of structure

More information

ONE LASER FOR EVERYONE

ONE LASER FOR EVERYONE ONE LASER FOR EVERYONE ABOUT OUR LASER MACHINE RESULTS DRIVEN With a diode 810nm is considered by many practitioners the best wavelength for laser hair removal offering optimal treatment results. FASTER

More information

The human respiratory system includes the nose, the larynx, and the lungs. This body system helps maintain homeostasis by

The human respiratory system includes the nose, the larynx, and the lungs. This body system helps maintain homeostasis by Study Island 1. During heatstroke, the body can't dispose of excess heat. As a result, the homeostatic balance is disturbed, and internal body temperatures can reach as much as 110. Heatstroke is dangerous

More information

UNBLEMISH. Regimen for Acne and Post Acne Marks

UNBLEMISH. Regimen for Acne and Post Acne Marks UNBLEMISH Regimen for Acne and Post Acne Marks How Does the UNBLEMISH Regimen Work? Based on Multi-Med Therapy, UNBLEMISH is a complete skincare system that combines active cosmetic and OTC ingredients

More information

Biological cell membranes

Biological cell membranes Unit 14: Cell biology. 14 2 Biological cell membranes The cell surface membrane surrounds the cell and acts as a barrier between the cell s contents and the environment. The cell membrane has multiple

More information

Chemistry Progression Framework

Chemistry Progression Framework Properties and uses of substances Periodic table and properties and uses of elements relative to their positions. SCN 3-15a Explore groups 1, 7 and 0 and their organisation in the periodic table. Atomic

More information

Metabolic Studies of Drug Candidates for Neurological Disorders and Asthma Based on GABA A Receptor Subtype Selective Ligands using Mass Spectrometry

Metabolic Studies of Drug Candidates for Neurological Disorders and Asthma Based on GABA A Receptor Subtype Selective Ligands using Mass Spectrometry Metabolic Studies of Drug Candidates for eurological Disorders and Asthma Based on GABA A Receptor Subtype Selective Ligands using Mass Spectrometry Revathi Kodali 1, Margaret L. Guthrie 1, Michael M.

More information

B2 3 Enzymes. 77 minutes. 77 marks. Page 1 of 25

B2 3 Enzymes. 77 minutes. 77 marks. Page 1 of 25 B2 3 Enzymes 77 minutes 77 marks Page of 25 Q. Enzymes have many uses in the home and in industry. (a) Which type of organism is used to produce these enzymes? Tick ( ) one box. Mammals Microorganisms

More information

The Integumentary System Dr. Ali Ebneshahidi

The Integumentary System Dr. Ali Ebneshahidi The Integumentary System Dr. Ali Ebneshahidi The Skin The integument system consists of the skin (cutaneous membrane) and its accessory organs. The skin is composed of three layers of tissue: the outer

More information

Image courtesy of Annemarie Börlind Beautiful Naturally

Image courtesy of Annemarie Börlind Beautiful Naturally b21 UV tanning In the United Kingdom, five per cent of the population use sun beds this is over three million people! Sun beds are designed to mimic the sun s effect on skin to create a tan. All therapists

More information

Eczema. The Skin The skin is the body's outer covering. It protects us against heat, light, injury and infection. It also regulates body temperature.

Eczema. The Skin The skin is the body's outer covering. It protects us against heat, light, injury and infection. It also regulates body temperature. Eczema Introduction Eczema is a term for several different types of skin inflammation. Most types cause red, swollen and itchy skin. Another name for eczema is dermatitis. While eczema is not dangerous,

More information

Laser Hair Removal Frequently Asked Questions

Laser Hair Removal Frequently Asked Questions Laser Hair Removal Frequently Asked Questions Q: What does laser hair removal feel like? Is it painful? A: Most people with lighter skin should feel no pain as they will undergo laser hair removal with

More information

HAIRCOLORING WHY PEOPLE COLOR THEIR HAIR HAIRCOLOR SERVICES. understanding color relationships PRIMARY COLORS SECONDARY COLORS

HAIRCOLORING WHY PEOPLE COLOR THEIR HAIR HAIRCOLOR SERVICES. understanding color relationships PRIMARY COLORS SECONDARY COLORS WHY PEOPLE COLOR THEIR HAIR HAIRCOLORING 21 HAIRCOLOR SERVICES Haircoloring includes the following processes: Depositing color on natural hair color Depositing color on previously colored hair Depositing

More information