STEM CELL ALLOGENEIC IN LYMPHOMA TRANSPLANTATION INTERNATIONAL SYMPOSIUM ON

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1 INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEM CELL TRANSPLANTATION IN LYMPHOMA Udine, October , 2005 Castello di Udine, Italy - Centro Congressi, Udine Fiere PROGRAM Presidents: Michele Baccarani Paolo Corradini Renato Fanin

2 ORGANIZERS Clinica Ematologica, DIRM, University of Udine Istituto di Ematologia ed Oncologia Clinica L. e A. Seragnoli University of Bologna Divisione di Ematologia, Istituto Nazionale per lo Studio e la Cura dei Tumori University of Milan SCIENTIFIC SECRETARIAT Francesco Zaja, Francesca Patriarca, Alessandra Sperotto Clinica Ematologica, P.zza S. Maria della Misericordia, Udine, Italy Phone Fax francesco.zaja@med.uniud.it ORGANIZING SECRETARIAT Studio E.R. Congressi Gruppo Triumph Via Marconi Bologna Italy Phone Fax ercongressi@gruppotriumph.it

3 INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEM CELL TRANSPLANTATION IN LYMPHOMA FACULTY Franco Aversa Michele Baccarani Andrea Bacigalupo Tiziano Barbui Philip J. Bierman Jan J. Cornelissen Paolo Corradini Giorgio Deliliers Lambertenghi Peter Dreger Brunangelo Falini Renato Fanin John G. Gribben Koi Izutsu Issa F. Khouri John E. Levine David G. Maloney Massimo F. Martelli Emma Morris Michael Pfreundchuh Franco Quadrifoglio Stephen P. Robinson Norbert Schmitz Shimon Slavin Davide Soligo Rainer Storb Corrado Tarella Sante Tura Koen van Besien Leo F. Verdonck Perugia, Italy Bologna, Italy Genova, Italy Bergamo, Italy Omaha, USA Rotterdam, The Netherlands Milano, Italy Milano, Italy Hamburg, Germany Perugia, Italy Udine, Italy London, United Kingdom Tokyo, Japan Houston, USA Ann Arbor, USA Seattle, USA Perugia, Italy London, United Kingdom Homburg/Saar, Germany Udine, Italy London, United Kingdom Hamburg, Germany Jerusalem, Israel Milano, Italy Seattle, USA Torino, Italy Bologna, Italy Chicago, USA Utrecht, The Netherlands

4 october 19, p.m. REGISTRATION 5.15 p.m. WELCOME ADDRESS FROM THE AUTHORITIES LECTURES Chairmen: F. Quadrifoglio - M. Baccarani 5.30 p.m. Treatment of non-hodgkin lymphomas: do we need to improve the results of conventional therapies? M. Pfreundchuh 6.15 p.m. From preclinical models to clinical trials: background and rationale of RIC transplant S. Slavin 7.30 p.m. WELCOME COCKTAIL

5 october 20, 2005 GENERAL SESSION Chairmen: A. Bacigalupo T. Barbui 8.30 a.m. Stem cell transplant in lymphomas: status of art, indications and choice of transplant R. Fanin 9.00 a.m. Identification of new lymphoma-associated molecules: an integrated antibody/proteomic/gene microarray approach B. Falini 9.30 a.m. Experimental and clinical evidence of graft versus lymphoma effect J.G. Gribben a.m. From high dose therapy to RIC R. Storb a.m. COFFEE BREAK LOW-GRADE LYMPHOMA SESSION Chairmen: I.F. Khouri C. Tarella a.m. Follicular lymphoma: results with conventional allogeneic transplants K. van Besien a.m. Follicular lymphoma: results with RIC transplants I.F. Khouri A.m. Mantle-cell lymphoma: is there a role for allogeneic transplants? D.G. Maloney a.m. Chronic lymphocytic leukemia: indications for transplant and conditioning options P. Dreger 1.15 p.m. LUNCH

6 october 20, 2005 HIGH-GRADE LYMPHOMA SESSION Chairman: R. Fanin - M. Pfreundchuh 2.30 p.m. Diffuse large B-cell lymphoma: results with conventional allogeneic transplants L.F. Verdonck 3.00 p.m. Diffuse large B-cell lymphoma results with RIC transplants S.P. Robinson 3.30 p.m. Peripheral T-cell lymphoma: salvage treatment with RIC transplants P. Corradini 4.00 p.m. COFFEE BREAK ROLE OF ALLOGENEIC TRANSPLANTS IN HODGKIN AND RARE LYMPHOMAS Chairmen: N. Schmitz - L.F. Verdonck 4.30 p.m. Hodgkin s lymphoma N. Schmitz 5.00 p.m. Cutaneous T-cell lymphoma D. Soligo 5.30 p.m. Lymphoblastic/Burkitt lymphoma J.E. Levine 6.00 p.m. How to monitor and treat EBV-related lymphoprolipherative disorders J.J. Cornelissen

7 october 21, a.m. selected ORAL communications Chairmen: J.G. Gribben - G. Lambertenghi Deliliers a.m. COFFEE BREAK ALLOGENEIC TRANSPLANTATION: ALTERNATIVE DONORS AND GVHD PREVENTION Chairmen: S. Tura - M.F. Martelli a.m. Which is the best stem cell source: syngeneic, sibling or unrelated donors? P.J. Bierman a.m. Results with unrelated donor transplant K. Izutsu a.m. Results with haploidentical donor transplant F. Aversa a.m. Role of monoclonal antibodies in GVHD prevention and treatment E. Morris

8 scientific information Oral communications A plenary session is devoted to oral communications. Eight communications will be selected among those received. All received abstracts will be published on the Proceedings Book. Abstracts should be submitted within August 31, 2005 by to the Organizing Secretariat Studio E.R. Congressi, Francesca Del Giudice f.delgiudice@gruppotriumph.it. Language The official conference language is English. No simultaneous translation will be provided. Badge All registered participants, speakers and attendants will be given a badge which they must wear to be admitted to the scientific sessions. Slides Slide must be in English. Computer videoprojection will be available. Other requirements should be communicated to the Organizing Secretariat as soon as possible. Slide should be handed to the slide center on floppy, cd-rom or pen drive one hour before the beginning of the session and collected at the end. Attendance certificate A certificate will be given to all participants at the end of the conference. ECM Application for ECM credits will be made. CHANGES Parts of the programme may be changed if necessary.

9 general information Conference venue Via Cotonificio, Torreano di Martignacco Udine- Italy How to reach conference venue By car: A4 Venezia - Trieste exit from the motorway at Udine Sud A23 Udine - Tarvisio exit from the motorway at Udine Nord By bus from railway station: bus n. 9 S-D

10 general information REGISTRATION FEE (in Euro - VAT included) Euro 100,00 The registration fee includes: Conference kit Proceedings book Attendance certificate Participation in the Scientific Sessions Coffee-breaks and lunch Welcome cocktail REGISTRATION Registration can only be accepted and confirmed after the registration form and fee have been received by the Organizing Secretariat Studio E.R. Congressi Gruppo Triumph. All payments must be done in Euro net of all bank charges and made out to Studio E.R. Congressi S.r.l. Please pay by Eurocheque or Foreign Cheque Bank transfer made out to Studio E.R. Congressi Srl Account n Cassa di Risparmio di Cesena-Agenzia n.29 Largo Caduti del Lavoro 1/A, Bologna, Italy Swift code CECRIT 2C IBAN IT36J ABI CAB CIN J Credit card Please send a copy of the bank transfer with the registration form. travel agency Cisalpina Tours Via Marconi, Bologna - Italy Tel Fax er@cisalpinatours.it

11 registration form Please, return this form to: STUDIO E.R. CONGRESSI - GRUPPO TRIUMPH Via Marconi Bologna BO Italy Phone Fax ercongressi@gruppotriumph.it LAST NAME FIRST NAME INSTITUTION/DEPARTMENT INSTITUTION ADDRESS PROFESSION DISCIPLINE PHONE MOBILE PHONE FAX PRIVATE ADDRESS ZIP CODE PROVINCE TAX PAYER S NUMBER FOR THE INVOICE: LAST NAME FIRST NAME ADDRESS CITY STATE/PROVINCE ZIP COUNTRY VAT NUMBER (P. IVA) TAX PAYER S NUMBER (COD. FISCALE) ALLOGENEIC STEM CELL TRANSPLANTATION IN LYMPHOMA

12 REGISTRATION FEES (in Euro - VAT included): 100,00 PAYMENT I enclose Eurocheque or Foreign Cheque of Euro Bank made out to Studio E.R. Congressi S.r.l. Number Bank transfer made out to Studio E.R. Congressi Srl Account n Cassa di Risparmio di Cesena-Agenzia n.29 Largo Caduti del Lavoro 1/A, Bologna, Italy Swift code CECRIT 2C IBAN IT36J ABI CAB CIN J Credit Card: Number Expiry date Owner Date of birth VISA MASTERCARD DINERS AMERICAN EXPRESS I enclose a copy of the bank transfer with the registration form. Registrations can only be accepted and confirmed when the registration form and fee have been received by the Organizing Secretariat Studio E.R. Congressi. In case of written cancellation before June 30th, 2004, 80% of the registration fee will be refunded. Signing this form and well informed on the legislative decree n. 196/2003 concerning "personal data processing" - particularly on the articles 4, 13, 21, 23, 24, 27, 37, 43, 44, 45 e I authorize Studio E.R. Congressi S.r.l. until written revocation to process and divulge my personal data within the limits of the above mentioned legislative decree and in accordance with the procedure laid down by the legislative decree. I give my assent provided that Studio E.R. Congressi S.r.l. complies with the regulations in force. I do not want that my personal data are divulged to third parties. Date Signature ALLOGENEIC STEM CELL TRANSPLANTATION IN LYMPHOMA

13 hotel registration form Please, return this form before July 31 st, 2005 to: CISALPINA TOURS Via Marconi, Bologna, Italy Tel Fax er@cisalpinatours.it LAST NAME FIRST NAME ADDRESS CITY ZIP CODE PHONE STATE/PROVINCE COUNTRY FAX NAME OF THE ACCOMPANYING PERSON FOR THE INVOICE: LAST NAME FIRST NAME ADDRESS CITY ZIP STATE/PROVINCE COUNTRY VAT NUMBER / TAX PAYER S NUMBER ALLOGENEIC STEM CELL TRANSPLANTATION IN LYMPHOMA

14 HOTEL CATEGORIES AND PRICES CATEGORY SINGLE DOUBLE SINGLE USE DOUBLE MIN. MAX. MIN. MAX. MIN. MAX. 100,00 102,00 100,00 114,00 130,00 150,00 65,00 70,00 75,00 78,00 108,00 111,00 Prices are expressed in Euro, per room, per night breakfast, services, 10% vat included. For each booked room, booking fee is of 10 Euros. HOTEL RESERVATION 4 stars 3 stars Single Double Double single use DATE OF ARRIVAL DATE OF DEPARTURE NIGHTS NUMBER In case of double room, indicate the name of your room-mate PAYMENT I enclose Eurocheque or Foreign Cheque of Euro Bank made out to Cisalpina tours SPA Number Bank transfer - All payments must be made in Euro and made out to Cisalpina Tours spa BANCA SAN PAOLO IMI (AGENZIA 14 - TORINO) ABI CAB C/C CIN P - IBAN: IT69P BIC:IBSPITTM Credit Card: VISA MASTERCARD DINERS AMERICAN EXPRESS Credit Card Nr Expiry Date In case of cancellation or no-show I authorize Cisalpina Tours Spa to debit my credit card for the amount due, as per cancellation policy. Cardholder s name Cardholder s signature (Signature is valid as authorization) ATTENTION: Please enclose a copy of the bank transfer with the registration form. In case of written cancellation before September 10, 2005,80% of the registration fee will be refunded.after this date, the total amount will be charged. Signing this form and well informed on the legislative decree n. 196/2003 concerning "personal data processing" - particularly on the articles 4, 13, 21, 23, 24, 27, 37, 43, 44, 45 e I authorize Studio E.R. Congressi S.r.l. until written revocation to process and divulge my personal data within the limits of the above mentioned legislative decree and in accordance with the procedure laid down by the legislative decree. I give my assent provided that Studio E.R. Congressi S.r.l. complies with the regulations in force. I do not want that my personal data are divulged to third parties. Date Signature

15 Information on legislative decree n. 196/2003 According to art. 13, Legislative decree no. 196/2003, and in relation to the processing of personal data, Triumph Viaggi & Incentive S.r.l and Studio E.R. Congressi Srl inform you of the following: l. Data processing purposes Your personal data will be processed by Triumph Viaggi & Incentive S.r.l. and Studio E.R. Congressi Srl for managing, accounting, statistical, commercial, marketing and/or promoting purposes and this by processing, comparing, divulging or employing these very data. 2. Data Processing modality Data will be processed by appropriate devices ensuring their security and confidentiality. Data could be also processed by automatic machines employed to process, store and transmit the very data. 3. Obligatoriness of personal data bestowal To be registered in the congresses we organize, you are obligated to give your data. 4. Data communication, diffusion and transfer Your data can be given to organizers of the congress and to the companies sponsoring the event as well as to other companies, authorities, consortia or associations that could divulge these data to their members, users and other related people within the limits of their institutional purposes. The only objective is to inform the person concerned about the existence of similar initiatives or to supply him with other information that could be deemed interesting. Furthermore, the above mentioned data can be given/divulged to companies, authorities, consortia and association working in Italy or in the EC countries having the same objectives as stated before. 5. Rights of interested parties You have the right to know, consulting the register specified in the art. 154 sub-section 1 letter l) of the legislative decree 196/2003, the existence of data processing; you can partially or entirely oppose, for legitimate reasons, the processing of your data, even if these data are relevant to the objective of data collection. Furthermore you can prevent his data from being used for commercial purposes, market surveys, advertisement for direct selling or interactive commercials. You are acknowledged exercise of rights as per art. 7, Legislative decree 196/2003, the complete text of which is given in the enclosure. 6. The owner of the data processing The owners of the data processing are Triumph Viaggi & Incentive S.r.l Via Lucilio, Roma and Studio E.R. Congressi Srl, via Marconi 36, Bologna. The list of the people responsible of the processing itself is kept updated, and you can easily consult it sending a written communication to the above address. Data will be held into the Triumph Viaggi & Incentive S.r.l and Studio E.R. Congressi Srl buildings, as long as the law prescribes. Article 7 of the legislative decree 196/2003 right of access to personal data and other rights 1. The person concerned has the right to obtain confirmation of the existence of personal data and information regarding him/her even though not recorded yet and their disclosure under an intelligible form. 2. The person concerned is entitled to be informed of: a) the origin of personal data and information; b) data treatment purposes and ways; c) the logic followed in the event of data treatment being carried out with electronic tools; d) the details to identify the owner, the persons in charge and the representative appointed under article 5, paragraph 2; e) the people or groups of people to whom personal data and information can be disclosed or who may come to know them in their capacity as representative appointed in the State territory or persons in charge. 3. The person concerned has the right to obtain: a) updating, correction or where interested in this process supplementation of data; b) cancellation, turning into anonymous data or the block of data treated by infringing the law, including data and information which need not be kept in relation to the purposes for which data and information were collected or subsequently treated; c) a certificate stating that the operations under sub-paragraphs a) and b) - including their content have been communicated to those to whom data and information were provided or disclosed, except the case when this proves to be impossible or entails the use of such an amount of means which is overtly non commensurate with the right which is protected. 4. The person concerned has to right to wholly or partially refuse: a) treatment of personal data and information regarding him/her for legitimate reasons, even though they are relevant to the aim of collection; b) treatment of personal data regarding him/her for the purposes of sending advertising material, direct sale or performance of market studies or commercial communications.

16 ORGANIZING SECRETARIAT Studio E.R. Congressi Gruppo Triumph Via Marconi Bologna Italy Phone Fax ercongressi@gruppotriumph.it