13TH INTERNATIONAL ULTMANN Chicago Lymphoma Symposium. May 6 7, 2016 THE UNIVERSITY OF CHICAGO SYMPOSIUM CO-CHAIRS

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1 THE UNIVERSITY OF CHICAGO 13TH INTERNATIONAL ULTMANN Chicago Lymphoma Symposium May 6 7, 2016 SYMPOSIUM CO-CHAIRS Sonali M. Smith, MD Andrew M. Evens, DO, MSc Tufts Medical Center Barbara Pro, MD Northwestern University Register online at: W CHICAGO CITY CENTER 172 West Adams Street Chicago, IL Join us for the 13th International Ultmann Chicago Lymphoma Symposium (IUCLS), an annual conference dedicated solely to the science and clinical care of lymphoma, hosted by the esteemed University of Chicago. The goal of this educational activity is to facilitate a forum for physicians, researchers, and other allied healthcare professionals to discuss biologic, diagnostic, and therapeutic aspects of Hodgkin and non-hodgkin lymphomas. 1 3 T H U L T M A N N MAY 6 7, 2016, CHICAGO, IL

2 SYMPOSIUM DESCRIPTION The International Ultmann Chicago Lymphoma Symposium (IUCLS) is an annual conference dedicated solely to the science and clinical care of lymphoma. It has been organized to honor the achievements of Dr. John Ultmann, a pioneer in the treatment of lymphoma, who devoted his life to the understanding of this disease. He was particularly known for his work on the staging of Hodgkin lymphoma and the utility of staging as a guide for treatment. We are fortunate to have a multitude of the world s experts in lymphoma speak each year at the conference. The audience is comprised of regional practicing oncologists, advanced nurse practitioners and physician assistants, residents, fellows, and the Chicago academic community that includes five academic centers. This year s program in May 2016 represents the 13th IUCLS. This is a certified continuing medical education (CME) activity that focuses on the biologic, diagnostic, and therapeutic aspects of Hodgkin and non-hodgkin lymphomas. The format of the meeting includes a combination of expert presentations, interactive case discussions, poster/abstract presentations, and an opportunity for question-and-answer debates. The IUCLS is a two-day meeting held Friday afternoon and Saturday morning and early afternoon at the W Chicago City Center hotel. Friday afternoon concentrates on the scientific and translational aspects of lymphoma, while Saturday has a clinical focus. LEARNING OBJECTIVES At the conclusion of this educational activity, participants will be able to: Recognize important targets in Waldenström macroglobulinemia that impact treatment Describe the 2016 WHO criteria for lymphoma Identify new diagnostics platforms that can be utilized in the treatment of DLBCL Implement current treatment strategies in Hodgkin lymphoma at various stages and in special populations Discuss the current allogeneic stem cell transplant options in lymphoma Learn how biologic insights may improve treatment of cutaneous t-cell lymphomas Please join us for what promises to be an informative and thought-provoking conference! CALL FOR ABSTRACTS Abstract submissions are now being accepted! The abstract submission deadline is Tuesday, April 5, Additional information at chicagolymphoma.com/call-for-abstracts/. TARGET AUDIENCE The symposium has been designed for medical hematologists/oncologists, radiation oncologists, pathologists, surgical oncologists, fellows-in-training, oncology nurses, and allied health professionals committed to the prevention, management, and elimination of lymphoma. ACCREDITATION AND CREDIT DESIGNATION Pritzker School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. GENERAL SESSIONS (FRIDAY and SATURDAY) Pritzker School of Medicine designates this live activity for a maximum 9 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Nurses and other healthcare professionals will receive a Certificate of Participation. For information on the applicability and acceptance of Certificates of Participation for educational activities certified for AMA PRA Category 1 Credit from organizations accredited by the ACCME, please consult your professional licensing board. EDUCATIONAL GRANTS/COMMERCIAL SUPPORT A complete listing of commercial support received will be provided in the conference materials.

3 LOCATION AND ACCOMMODATIONS The conference will take place at W Chicago City Center 172 West Adams Street Chicago, IL / wchicagocitycenter.com Set in the middle of the famed Chicago Loop, W Chicago City Center is close to the Willis Tower (formerly the Sears Tower), the Art Institute of Chicago, music at Millennium Park, and the theater district. The W is a world-class venue, and Chicago is a world-class city. After the conference adjourns each day you can enjoy premium shopping, beautiful architecture, famous art, and award-winning theater just a short walk away. Step out the Windy City surrounds you. We are pleased to offer a special discounted rate of $ per night for single and $ per night for double occupancy during the conference. Room reservations must be made by 5:00pm CST on Tuesday, April 15, 2016 to guarantee the reduced rate. After the cut-off date, it is at the hotel s discretion whether to accept additional reservations, which will be subject to prevailing group rates based on availability. All rates are subject to state and city taxes and must be guaranteed and accompanied by a first night room deposit or guaranteed with a major credit card. Check-in time is 3pm and check-out time is 12 pm. Individual reservations can be cancelled 24 hours or more prior to arrival without penalty. If a reservation is cancelled within 24 hours of arrival, a one (1) night room and tax charge will apply. To reserve a room at this special rate, please call the hotel toll free at and identify yourself as part of the University of Chicago International Ultmann Chicago Lymphoma Symposium 2015 or book online at Parking: The daily parking fee at the W Chicago City Center is $25 for local registered attendees driving to the conference. There are other parking options available near the hotel. For additional parking options, please visit our website at Chicago is truly a city with something for everyone! To help plan your stay in Chicago visit: reserves the right to cancel or postpone this conference due to unforeseen circumstances. In the unlikely event this activity must be cancelled or postponed, the registration fee will be refunded; however, is not responsible for any related costs, charges, or expenses to participants, including fees assessed by airline/travel/lodging agencies. Disclosure Declarations: As a provider accredited by the ACCME, Pritzker School of Medicine, requires everyone who is in a position to control the content of an education activity to disclose all relevant financial relationships with any commercial interest. This includes any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. The ACCME defines relevant financial relationships as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner that could create a conflict of interest. Mechanisms are in place to identify and resolve any potential conflict of interest prior to the start of the activity. Additionally, Pritzker School of Medicine, requires Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.

4 SYMPOSIUM CO-CHAIRS Sonali M. Smith, MD Associate Section of Hematology/Oncology Director, Lymphoma Program Chicago, IL Andrew M. Evens, DO, MSc and Chief, Division of Hematology/Oncology Tufts University School of Medicine Director, Tufts Cancer Center Tufts Medical Center Boston, MA Barbara Pro, MD Section of Hematology/Oncology Northwestern University Feinberg School of Medicine Robert H. Lurie Comprehensive Cancer Center of Northwestern University Chicago, IL INVITED SPEAKERS David Weinstock, MD Associate Harvard Medical School Boston, MA Irene Ghobrial, MD Associate Director, Michele & Stephen Kirsch Laboratory Senior Physician Dana-Farber Cancer Institute Harvard Medical School David Scott, MD, MBChB Clinician-scientist Centre for Lymphoid Cancer, British Columbia Cancer Agency Kieron M. Dunleavy, MD Staff Clinician Lymphoid Malignancies Branch Center for Cancer Research National Cancer Institute National Institutes of Health Y. Lynn Wang, MD, PhD, FCAP Professor Division Director, Division of Genomic and Molecular Pathology Department of Pathology Chicago, IL Elaine S. Jaffe, MD Senior Investigator Laboratory of Pathology Head, Hematopathology Section Center for Cancer Research National Cancer Institute National Institutes of Health Reem Karmali, MD Assistant Division of Hematology, Oncology, and Cell Therapy Rush University Medical Center/Rush University Chicago, IL Matthew Lunning, DO Assistant Professor, Internal Medicine Division of Oncology and Hematology University of Nebraska Medical Center Omaha, NE Mehdi Hamadani, MD Associate Division of Hematology and Oncology Medical College of Wisconsin Lindsay Morton, PhD Senior Investigator National Cancer Institute Division of Cancer Epidemiology & Genetics, Radiation Epidemiology Branch National Institutes of Health Bethesda, MD Youn H Kim, MD Joanne and Peter Haas Jr. Professor for Cutaneous Lymphoma Research Professor of Dermatology Director, Multidisciplinary Cutaneous Lymphoma Clinic Medical Director, Photopheresis Service Stanford University Medical Center Barbara Pro, MD Section of Hematology/Oncology Northwestern University Feinberg School of Medicine Robert H. Lurie Comprehensive Cancer Center of Northwestern University Michele Ghielmini, MD, PhD Head of the Medical Oncology Department Medical Director of the Oncology Institute of Southern Switzerland in Bellinzona Honorary at the University of Bern, Switzerland Ann S. LaCasce, MD Assistant Director, Dana-Farber/Partners CancerCare Hematology-Medical Oncology Fellowship Program Senior Physician Dana-Farber Cancer Institute Harvard Medical School Craig H. Moskowitz, MD Clinical Director, Division of Hematologic Oncology Steven A. Greenberg Chair Memorial Sloan Kettering Cancer Center Andrew Evens, DO, MSc Chief, Division of Hematology/Oncology Tufts University School of Medicine Director, Tufts Cancer Center Tufts Medical Center ADVISORY COMMITTEE Timothy S. Fenske, MD Associate Division of Hematology & Oncology Medical College of Wisconsin Milwaukee, WI Leo Gordon, MD Division of Hematology & Oncology Northwestern University Feinberg School of Medicine Reem Karmali, MD Assistant Division of Hematology, Oncology, and Cell Therapy Rush University Medical Center/Rush University Justin Kline, MD Assistant Chadi Nabhan, MD, FACP Associate Medical Director, Clinical Cancer Center and Cancer Clinics David Peace, MD Director, Hematology and Medical Oncology Training Program University of Illinois at Chicago Scott Smith, MD, PhD, FACP Cardinal Bernardin Cancer Center Loyola University Chicago Medical Center Patrick Stiff, MD Coleman Professor of Oncology Director Cancer Center FCO Division director, Hematology/ Oncology Medical Director, Cardinal Bernardin Cancer Center Loyola University Chicago Medical Center FACULTY DISCLOSURE It is the policy of the University of Chicago to ensure balance, independence, objectivity, and scientific rigor in all its individually sponsored or jointly sponsored educational activities. Individuals who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Mechanisms to ensure that presentations are free from commercial bias are in place. Faculty will also disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Full disclosure of this information will be published in the activity materials.

5 SYMPOSIUM AGENDA FRIDAY, MAY 6, :00 pm REGISTRATION 1:00-1:10 Welcome and Introduction 1:10-1:40 Translating Scientific Discovery in T-Cell Lymphoma: Current and Future States David Weinstock, MD 1:40-2:10 From Biology to Therapy in Waldenström Macroglobulinemia Irene Ghobrial, MD 2:10-2:40 Integration of Diagnostic Platforms in DLBCL David Scott, MD, MBChB 2:40-3:00 REFRESHMENT BREAK 3:00-3:30 MRD Testing in Lymphoma: Current Tools and Emerging Clinical Applications Kieran Dunleavy, MD 3:30-4:00 BTK Resistance and Implications for Practice Lynn Wang, MD, PhD, FCAP SCIENTIFIC KEYNOTE 4:00-5:00 Preview of WHO 2016: What the Lymphoma Clinician (and Pathologist) Needs to Know Elaine Jaffe, MD 5:00-6:15 pm ABSTRACT/POSTER HIGHLIGHTS AND WELCOME RECEPTION EXHIBITS OPEN 1:00 6:15 pm

6 SATURDAY, MAY 7, :00 am REGISTRATION AND CONTINENTAL BREAKFAST 8:00-8:10 Welcome and Introduction DEBATES IN LYMPHOMA 8:10-9:10 Debates in Lymphoma: No Role for Surveillance Imaging in Lymphoma Reem Karmali, MD (PRO) vs. Matthew Lunning, DO (CON)) 9:10-9:40 Beyond Sibling Donors: Current Options for Allogenic Stem Cell Transplant in Lymphoma Medhi Hamadani, MD CLIP HERE TO MAIL IN REGISTRATION FORM 9:40-10:10 What Causes Lymphoma: What Should We Tell Our Patients Lindsay Morton, PhD 10:10-10:30 REFRESHMENT BREAK 10:30-11:00 Emerging targets in cutaneous T-cell lymphoma Youn Kim, MD 11:00-11:30 Initial Treatment of T-cell Lymphoma Barbara Pro, MD CLINICAL KEYNOTE 11:30-12:30 The Evolution Towards Non-Chemotherapeutic Approaches for Indolent Lymphomas: Pitfalls and Lessons Learned Michele Ghielmini, MD, PhD 12:30-1:30 pm LUNCH 1:30-2:00 Early Stage Hodgkin Lymphoma in 2016: Taking Stock of the Evidence Ann LaCasce, MD 2:00-2:30 Optimizing Outcomes for Relapsed Hodgkin Lymphoma Craig Moskowitz, MD 2:30-3:00 Management of Special Populations with Hodgkin Lymphoma Andy Evens, DO, MSc 3:00 pm ADJOURN EXHIBITS OPEN 7:00 am 3:00 pm Program agenda and speaker selection subject to change.

7 REGISTRATION HOW TO REGISTER ONLINE (credit card payment only) To pay by check, you must mail your registration with payment to: MAIL Center for Continuing Medical Education c/o Chicago Lymphoma East 61st Street, Suite 101 Chicago, IL The registration fee includes symposium materials, an electronic syllabus, continental breakfast, refreshment breaks, lunch, welcome reception, and poster viewing. You may register online or via U.S. mail. While registration is open until the start of the meeting, we encourage early registration to enable us to provide the best possible service to participants. On or Before April 4 Between April 5- May 6 Onsite Registration May 6-7 Physician $225 $275 $325 Industry $400 $550 $600 Nurse/Other Health Professionals $125 $150 $175 Resident/Fellow (fax letter of verification to ) $75 $100 $125 PAYMENT o Check enclosed (U.S. funds only), payable to University of Chicago (Tax ID# ) Total $ CONTACT INFORMATION Name Degree Specialty Organization Mailing Address City State Zip Phone Fax PLEASE CHECK ALL THAT APPLY o You must check this box if you do not want your mailing address shared with conference participants and exhibitors (if applicable). Do you plan to attend the Friday Poster Viewing and Welcome Reception? o Yes o No Please tell us how you found out about this activity, check all that apply: o Colleague o Save the Date o Brochure o Internet o o Journal Ad o Previous Attendance o Other CANCELLATION POLICY If you cancel your participation in this conference, your registration fee, less a $100 administrative fee, will be refunded when written notification is received by April 8, No refunds will be issued after April 8, ACCESSIBILITY is committed to providing equal access appropriate to need and circumstance and complies fully with the legal requirements of the Americans with Disabilities Act. If you are in need of special accommodation, please contact our office at or via at cme@bsd.uchicago.edu. For additional information about this activity, please call the Center for Continuing Medical Education at

8 1 3 T H U L T M A N N MAY 6 7, 2016, CHICAGO, IL Center for Continuing Medical Education 950 East 61st Street, Chicago, IL TH INTERNATIONAL ULTMANN Chicago Lymphoma Symposium May 6-7, 2016 W Chicago City Center 172 West Adams Street Chicago, IL NON-PROFIT ORGANIZATION U.S. POSTAGE PAID DLC PLEASE POST