An advanced diagnostic

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1 Pelvi-perineal myofascial syndromes: clinical presentation, differential diagnosis and electrophysiological characteristics An advanced diagnostic Dr. Zarza Dr. Itza

2 There's an elephant in this room

3 What we need?

4 Epidemiology Of 283 consecutive admissions to a pain clinic, 85% were diagnosed as suffering from myofascial syndrome somewhere in the body [1]. In a multicenter study done in urological outpatient centers of 28 hospitals in Italy with 5,540 patients, the prevalence of the syndrome was 13.8% [2]. [1]Skootsky SA, Jaiger B, Oye RK. Prevalence of myofascial pain in general internal medicine practice. West J Med 1989; 151: [2}Bartoletti R, et al. Prevalence, incidence estimation, risk factors and characterization of chronic prostatitis / chronic pelvic pain syndrome in urological: results of a multicenter case-control observational study. J Urol Dec ;178(6): ; discussion 2415.

5 Specialists involved

6 Goals We present the typical symptoms of the myofascial pain syndromes in the pelvic floor We present advanced neurophysiological tests for getting a proper diagnosis We make a differential diagnostic

7 More frequent myofascial syndromes Levator ani syndrome Oblique abdominal syndrome Obturator internus syndrome Piriformis syndrome Bulbocavernosus syndrome

8 Levator ani syndrome Anatomy Referred pain pattern

9 Levator ani syndrome Etiology of male Chronic bacterial prostatitis Chronic nonbacterial prostatitis-cpp Anorectal conditions Urological surgery Chronic constipation Sports injuries PNE Post PN decompression Etiology of female Anorectal conditions Chronic constipation Episiotomy scars Sphincterotomy Urological surgery (mesh) Sports injuries PNE Post PN decompression

10 Levator ani syndrome Symptoms in male Increased urinary frequency and urgency Sensation of a golf ball in the rectum. Pain during and after ejaculation. Pain after defecation. Pain referred to the perineum and the penis Pain when sitting Symptoms in female Pain in vagina Pain in perirectal area Pain or discomfort in the lower abdomen. Increased urinary frequency and urgency. Pain when sitting

11 Levator ani syndrome - highlights It's the most common myofascial syndrome in patients with CPP (almost 100% of cases ) Most important location of TrPs in men with CPP. Be careful with scars of episiotomy, it can simulate PNE in some cases Irritable bowel syndrome, levator ani syndrome, proctalgia fugax and chronic pelvic and perineal pain. Watier A, Rigaud J, Labat JJ. Prog Urol Nov;20(12):

12 More frequent myofascial syndromes Levator ani syndrome Oblique abdominal syndrome Obturator internus syndrome Piriformis syndrome Bulbocavernosus syndrome

13 Oblique abdominal syndrome Referred pain pattern Anatomy

14 Oblique abdominal syndrome Etiology Inguinal herniorrhaphy Appendectomy Orchiectomy Caesarean section Trauma Sports injuries Pelvic surgery TVT, TOT Symptoms Pain irradiation to the external genitalia (testicles, labia majora) Pain in abdominal wall Pain in the lower abdomen

15 Oblique abdominal syndrome -highlights Some patients have undergone surgery unnecessarily (orchiectomy) Many times it is associated to iliohypogastric and/or ilioinguinal neuropathy. Sometimes it is associated to iliohypogastric and/or ilioinguinal entrapment Abdominal myofascial pain syndrome must be considered in the differential diagnosis of chronic pelvic pain. Montenegro ML, Gomide LB, Mateus-Vasconcelos EL, et al. Obstet Gynecol Reprod Biol Nov;147(1):21-4.

16 More frequent myofascial syndromes Levator ani syndrome Oblique abdominal syndrome Obturator internus syndrome Piriformis syndrome Bulbocavernosus syndrome

17 Referred pain pattern Anatomy Obturator internus syndrome

18 Obturator internus syndrome Etiology CBP CNBP-CPP Anorectal conditions Urological surgery (mesh, TOT, TVT) Sports PNE Post PN decompression Symptoms Sensation of a golf ball in the rectum Pain down to the back of the thigh Vaginal and vulvar pain. Urethral pain in women. Pain in the entire pelvic floor.

19 Obturator internus syndrome -highlights May simulate PNE, the nerve and the muscle are closely related, palpation of the area causes burning and intense pain. Related to PNE (Alcock's canal) Typical complication of PN decompression Multiple associations with other syndromes Myofascial pain syndrome affecting the piriformis and the obturator internus muscle. Dalmau-Carolà J. Pain Pract Dec;5(4):361-3.

20 More frequent myofascial syndromes Levator ani syndrome Oblique abdominal syndrome Obturator internus syndrome Piriformis syndrome Bulbocavernosus syndrome

21 Anatomy Referred pain pattern

22 Piriformis syndrome Etiology Muscle overload Trauma Sports injuries Nerve and vascular entrapment by piriformis Symptoms Pain in low back Pain in perineum Dyspareunia Erectile dysfunction Pain in buttock and hip Pain during defecation Pain in posterior thigh and leg

23 Piriformis syndrome - highlights PS frequently simulates a pseudo sciatica Could cause several entrapments: -Sciatic nerve -PNE -Gluteal nerves -Posterior femoral cutaneous nerve Piriformis syndrome: implications of anatomical variations, diagnostic techniques, and treatment options. Cassidy L, Walters A, Bubb K, Shoja MM, Shane Tubbs R, Loukas M. Surg Radiol Anat Feb 12

24 More frequent myofascial syndromes Levator ani syndrome Oblique abdominal syndrome Obturator internus syndrome Piriformis syndrome Bulbocavernosus syndrome

25

26 Bulbocavernosus syndrome Etiology Rare alone, usually associated to other myofascial pain syndromes Vascular disease (varicose) Pudendal neuropathy Overactive bladder Associated to PNE ( an Aixen-Provence criteria) Post menopausal women Symptoms Pain in the base of the penis and perineum. Pain in the ventral aspect of the penis Erectile dysfunction Dyspareunia (female) Pain in perineum (female) Sexual arousal out of sexual context

27 Bulbocavernosus syndrome - highlights The former persistent sexual arousal syndrome currently renamed as persistent genital arousal disorder or restless genitalia syndrome The patients feel sexual arousal in absence of desire. Goldmeier D, Leiblum SR. Persistent genital arousal in women A new syndrome entity. Int J STD AIDS 2006;17:215 6.

28 Differential diagnosis Polyneuropathy, starting with pudendal neuropathy Vascular disease, starting with pudendal neuropathy Ilioinguinal neuropathy, simulating a testicular pain problem

29 Case nº1 Male 54, lives in Colombia History of hypothyroidism Started with typical pain of pudendal neuropathy (when sitting, anal burning, penis pain, etc..) Treatments: PN blocks, anticonvulsants, etc.. No results

30 Neurophysiological findings: Polyneuropathy Right DMLPN (2,0 ms) normal Left DMLPN (2.0 ms) normal External anal sphincter and levator ani muscle Turns/ amplitude Index: normal PN sensory evoked potential P40 (46 ms) delayed Diminished sensory conduction velocities of the left and right soleus muscles

31 Case nº2 Female 37, lives in Argentina Started with pain in the clitoris on the right side, when she was a child. No urinary problems. No sex possible Treatments: ADT, anticonvulsants, etc.. No results

32 Neurophysiological findings: Vascular disease Right DMLPN (2,6 ms) delayed Left DMLPN (2.0 ms) normal Right pelvic varicocele is associated with vessels around the right vulvar and vaginal region Left PN sensory evoked potential P40 (65ms) delayed Right PN sensory evoked potential P40 (40ms) normal

33 Case nº3 Male 25, lives in Spain Muscle overload, sports injury Started with testicular pain Different treatments (including right varicocele operated, anticonvulsants, etc.. No results

34 Neurophysiological findings: Ilioinguinal neuropathy Right sensory conduction velocity (32m/s) Diminished Left sensory conduction velocity (45m/s) normal External anal sphincter and levator ani muscle Turns/ amplitude Index: abnormal

35 going one step further... Have a nice day and pleasant dreams

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