Familieorienteret alkoholbehandling versus Individuel alkoholbehandling for

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "Familieorienteret alkoholbehandling versus Individuel alkoholbehandling for"

Transcription

1 Familieorienteret alkoholbehandling versus Individuel alkoholbehandling for alkoholafhængighed Review information Authors Sundhedsstyrelsen 1 1 Sundhedsstyrelsen Citation example: S. Familieorienteret alkoholbehandling versus Individuel alkoholbehandling for alkoholafhængighed. Cochrane Database of Systematic Reviews [Year], Issue [Issue]. Contact person [Empty name] Dates Assessed as Up-to-date: Date of Search: Next Stage Expected: Protocol First Published: Not specified Review First Published: Not specified Last Citation Issue: Not specified Review Manager 5.3 1

2 What's new Date / Event Description History Date / Event Description Characteristics of studies Characteristics of included studies Fals-Stewart 2005 Methods RCT Participants alcohol dependent with a spouse, living together for one year Interventions brief relationship therapy Outcomes Dyadic adjustment scale Notes USA, funded by national institue of drug abuse Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk participants were randomized, but no further information Allocation concealment (selection bias) Unclear risk no information on allocation concealment Blinding of participants and personnel (performance bias) High risk not possible due to the intervention Blinding of outcome assessment (detection bias) Unclear risk not described Incomplete outcome data (attrition bias) Low risk impution of missing data Selective reporting (reporting bias) Low risk not suspected due to the intervention tested Review Manager 5.3 2

3 Other bias Low risk not supected Fals-Stewart 2006 Methods RCT Participants alcohol dependent women with a spouse, living together for one year Interventions behavioral couple therapy Outcomes Dyadic adjustment scale Notes USA, funded by national institue of drug abuse Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk randomized by a computer Allocation concealment (selection bias) High risk group asignment were concealed until participant had there first session Blinding of participants and personnel (performance bias) High risk impossible Blinding of outcome assessment (detection bias) Unclear risk not described Incomplete outcome data (attrition bias) Unclear risk handling of missing data described Selective reporting (reporting bias) Low risk not supected Other bias Low risk Kelley 2002 Methods RCT Participants alcohol dependent men living with a partner for at least one year Interventions behavioral couple therapy Outcomes Dyadic adjustment scale Review Manager 5.3 3

4 Notes USA Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk just information that the participants were randomized Allocation concealment (selection bias) Unclear risk not described Blinding of participants and personnel (performance bias) High risk impossible Blinding of outcome assessment (detection bias) Unclear risk not described Incomplete outcome data (attrition bias) Low risk handling of missing data Selective reporting (reporting bias) Low risk not described Other bias Low risk not described Lam 2009 Methods RCT Participants alcohol dependent men living with a partner for at least one year Interventions behavioral couple therapy Outcomes Dyadic adjustment scale Notes USA Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk not described Allocation concealment (selection bias) Unclear risk not described Blinding of participants and personnel (performance bias) High risk not possible Review Manager 5.3 4

5 Blinding of outcome assessment (detection bias) Unclear risk not described Incomplete outcome data (attrition bias) Unclear risk handling of missing data Selective reporting (reporting bias) Low risk not suspected Other bias Low risk O'Farrell 1985 Methods RCT Participants alcohol dependent men living with a partner for at least one year Interventions behavioral couple therapy, couples group Outcomes Marital adjustments test Notes USA Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Low risk paper random numbers table Allocation concealment (selection bias) Unclear risk "unaware of treatment allocation until after assessment" Blinding of participants and personnel (performance bias) High risk not possible Blinding of outcome assessment (detection bias) Unclear risk not described Incomplete outcome data (attrition bias) High risk not analsyed for all randomised patients, n=36 Selective reporting (reporting bias) Low risk not suspected Other bias Low risk Review Manager 5.3 5

6 Vedel 2008 Methods RCT Participants alcohol dependece, and alcohol abuse (minority) Interventions Behavioural couple therapy Outcomes Maudssley Marital questionaire Notes Netherlands, grant from ZonMw Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk no information provided Allocation concealment (selection bias) Unclear risk no information provided Blinding of participants and personnel (performance bias) High risk not possible Blinding of outcome assessment (detection bias) Unclear risk no information provided Incomplete outcome data (attrition bias) Unclear risk no information provided Selective reporting (reporting bias) Unclear risk no information provided Other bias Unclear risk no information provided Walitzer 2004 Methods RCT Participants alcohol abuse at least 10 drinks/week Interventions behavioural couple therapy + alcohol focused treatment Outcomes Dyadic adjustment score Notes USA, funded by the national institute on alcohol abuse and alcoholics Review Manager 5.3 6

7 Risk of bias table Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk not described Allocation concealment (selection bias) Unclear risk not described Blinding of participants and personnel (performance bias) High risk not possible Blinding of outcome assessment (detection bias) Unclear risk not dscribed Incomplete outcome data (attrition bias) Unclear risk not described how missing data were handled Selective reporting (reporting bias) Unclear risk not described Other bias Unclear risk not described Footnotes Characteristics of excluded studies Footnotes Characteristics of studies awaiting classification Footnotes Characteristics of ongoing studies Footnotes Review Manager 5.3 7

8 Summary of findings tables Additional tables References to studies Included studies Fals-Stewart 2005 [Empty] Fals-Stewart 2006 [Empty] Kelley 2002 [Empty] Lam 2009 [Empty] O'Farrell 1985 [Empty] Vedel 2008 [Empty] Walitzer 2004 [Empty] Excluded studies Review Manager 5.3 8

9 Studies awaiting classification Ongoing studies Other references Additional references Other published versions of this review Data and analyses 1 family vs. individual, post treatment Outcome or Subgroup Studies Participants Statistical Method Effect Estimate 1.1 Family function (marital function), drinker Std. Mean Difference (IV, Random, 95% CI) 0.47 [0.11, 0.82] 1.2 Family function (marital function), non-drinker Std. Mean Difference (IV, Random, 95% CI) 0.32 [0.05, 0.59] 1.3 Children's pediatric symptom list 1 47 Mean Difference (IV, Fixed, 95% CI) [-10.94, 4.94] 1.4 Children with open cases with child protective services for target child 1 20 Risk Ratio (M-H, Fixed, 95% CI) 1.00 [0.26, 3.81] 1.5 Timeline Followback Interview Spousal Violence Male-to-Female Days Any Violence 1 20 Mean Difference (IV, Fixed, 95% CI) [-2.18, 1.70] 1.6 Timeline Followback Interview Spousal Violence Female-to-Male Days Any Violence (FMDAV) 1 20 Mean Difference (IV, Fixed, 95% CI) [-2.00, 1.72] Review Manager 5.3 9

10 2 family vs. individual, 6 to 12 month follow-up Outcome or Subgroup Studies Participants Statistical Method Effect Estimate 2.1 Family function (marital function), drinker Std. Mean Difference (IV, Random, 95% CI) 0.37 [0.05, 0.69] 2.2 Family function (marital function), non-drinker Std. Mean Difference (IV, Random, 95% CI) 0.40 [0.01, 0.79] 2.3 Children's pediatric symptom list 1 47 Mean Difference (IV, Fixed, 95% CI) [-14.66, 1.86] 2.4 Children with open cases with child protective services for target child 1 20 Risk Ratio (M-H, Fixed, 95% CI) 0.67 [0.14, 3.17] 2.5 Timeline Followback Interview Spousal Violence Male-to-Female Days Any Violence Mean Difference (IV, Random, 95% CI) [-2.55, 0.24] 2.6 Timeline Followback Interview Spousal Violence Female-to-Male Days Any Violence (FMDAV) Mean Difference (IV, Fixed, 95% CI) [-2.70, -0.24] Figures Figure 1 (Analysis 1.1) Review Manager

11 Forest plot of comparison: 1 family vs. individual, post treatment, outcome: 1.1 Family function (marital function), drinker. Figure 2 (Analysis 1.2) Forest plot of comparison: 1 family vs. individual, post treatment, outcome: 1.2 Family function (marital function), non-drinker. Figure 3 (Analysis 1.3) Forest plot of comparison: 1 family vs. individual, post treatment, outcome: 1.3 Children's pediatric symptom list. Review Manager

12 Figure 4 (Analysis 1.4) Forest plot of comparison: 1 family vs. individual, post treatment, outcome: 1.4 Children with open cases with child protective services for target child. Figure 5 (Analysis 1.5) Forest plot of comparison: 1 family vs. individual, post treatment, outcome: 1.5 Timeline Followback Interview Spousal Violence Male-to-Female Days Any Violence. Figure 6 (Analysis 1.6) Forest plot of comparison: 1 family vs. individual, post treatment, outcome: 1.6 Timeline Followback Interview Spousal Violence Female-to-Male Days Any Violence (FMDAV). Review Manager

13 Figure 7 (Analysis 2.1) Forest plot of comparison: 2 family vs. individual, 6 to 12 month follow-up, outcome: 2.1 Family function (marital function), drinker. Figure 8 (Analysis 2.2) Forest plot of comparison: 2 family vs. individual, 6 to 12 month follow-up, outcome: 2.2 Family function (marital function), non-drinker. Review Manager

14 Figure 9 (Analysis 2.3) Forest plot of comparison: 2 family vs. individual, 6 to 12 month follow-up, outcome: 2.3 Children's pediatric symptom list. Figure 10 (Analysis 2.4) Forest plot of comparison: 2 family vs. individual, 6 to 12 month follow-up, outcome: 2.4 Children with open cases with child protective services for target child. Figure 11 (Analysis 2.5) Forest plot of comparison: 2 family vs. individual, 6 to 12 month follow-up, outcome: 2.5 Timeline Followback Interview Spousal Violence Male-to-Female Days Any Violence. Review Manager

15 Figure 12 (Analysis 2.6) Forest plot of comparison: 2 family vs. individual, 6 to 12 month follow-up, outcome: 2.6 Timeline Followback Interview Spousal Violence Female-to-Male Days Any Violence (FMDAV). Review Manager

NKR 13 Alkoholbehandling. Disulfiram for alcohol dependency

NKR 13 Alkoholbehandling. Disulfiram for alcohol dependency NKR 13 Alkoholbehandling. Disulfiram for alcohol dependency Review information Authors Sundhedsstyrelsen 1 1 [Empty affiliation] Citation example: S. NKR 13 Alkoholbehandling. Disulfiram for alcohol dependency.

More information

Characteristics of studies

Characteristics of studies PICO 6 for ALKO DOB FINAL Review information Authors [Empty name] 1 1 [Empty affiliation] Citation example: [Empty name]. PICO 6 for ALKO DOB FINAL. Cochrane Database of Systematic Reviews [Year], Issue

More information

NKR 30 PICO 6 Ledmobiliserende teknikker eller øvelsesterapi

NKR 30 PICO 6 Ledmobiliserende teknikker eller øvelsesterapi NKR 30 PICO 6 Ledmobiliserende teknikker eller øvelsesterapi Review information Authors Sundhedsstyrelsen 1 1 [Empty affiliation] Citation example: Sundhedsstyrelsen. NKR 30 PICO 6 Ledmobiliserende teknikker

More information

CBT versus TAU for ADHD Review information

CBT versus TAU for ADHD Review information CBT versus TAU for ADHD Review information Authors [Empty name] 1, Brynjar Emilsson 1 1 [Empty affiliation] Citation example: [Empty name], Emilsson B. CBT versus TAU for ADHD. Cochrane Database of Systematic

More information

NKR 38: PICO 2: Træning ved opstart af ADT vs vanlig aktivitet?

NKR 38: PICO 2: Træning ved opstart af ADT vs vanlig aktivitet? NKR 38: PICO 2: Træning ved opstart af ADT vs vanlig aktivitet? Review information Authors [Empty name] 1, The Danish Health and Medicines Authority 1 1 [Empty affiliation] Citation example: [Empty name],

More information

NKR 33 Urininkontinens, PICO 3: Bør kvinder med urininkontinens tilbydes behandling

NKR 33 Urininkontinens, PICO 3: Bør kvinder med urininkontinens tilbydes behandling NKR 33 Urininkontinens, PICO 3: Bør kvinder med urininkontinens tilbydes behandling med et vaginalt hjælpemiddel? Review information Authors Sundhedsstyrelsen 1 1 The Danish Health and Medicines Authority

More information

Cochrane Review: Psychological treatments for depression and anxiety in dementia and mild cognitive impairment

Cochrane Review: Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 23 rd Alzheimer Europe Conference St. Julian's, Malta, 2013 Cochrane Review: Psychological treatments for depression and anxiety in dementia and mild cognitive impairment Orgeta V, Qazi A, Spector A E,

More information

Critical appraisal of randomised controlled trials

Critical appraisal of randomised controlled trials Critical appraisal of randomised controlled trials Dr Kamal R. Mahtani BSc PhD MBBS PGDip MRCGP GP and Clinical Lecturer Centre for Evidence Based Medicine University of Oxford November 2014 Sickness

More information

Alcohol screening and brief intervention in primary care: no evidence of efficacy for dependence

Alcohol screening and brief intervention in primary care: no evidence of efficacy for dependence Systematic review: Alcohol screening and brief intervention in primary care: no evidence of efficacy for dependence Richard Saitz MD, MPH, FACP, FASAM Professor of Medicine & Epidemiology Boston University

More information

Distance Education as a Training Tool for Health Professionals: Systematic Review and Meta-Analysis of Randomized Trials

Distance Education as a Training Tool for Health Professionals: Systematic Review and Meta-Analysis of Randomized Trials Distance Education as a Training Tool for Health Professionals: Systematic Review and Meta-Analysis of Randomized Trials Patrícia de Oliveira Dias, Crislaine Padilha, Silvia Goldmeier and Clarissa Rodrigues

More information

Biostat Methods STAT 5820/6910 Handout #6: Intro. to Clinical Trials (Matthews text)

Biostat Methods STAT 5820/6910 Handout #6: Intro. to Clinical Trials (Matthews text) Biostat Methods STAT 5820/6910 Handout #6: Intro. to Clinical Trials (Matthews text) Key features of RCT (randomized controlled trial) One group (treatment) receives its treatment at the same time another

More information

Low-fat or low-carb diet for long-term weight loss Student EBM presentations

Low-fat or low-carb diet for long-term weight loss Student EBM presentations Low-fat or low-carb diet for long-term weight loss Student EBM presentations Kin Seng Tong & Freya Glover University of Oxford 6 October 2015 The clinical scenario Mr. Smith is a 25-year-old receptionist

More information

Managing depression after stroke. Presented by Maree Hackett

Managing depression after stroke. Presented by Maree Hackett Managing depression after stroke Presented by Maree Hackett After stroke Physical changes We can see these Depression Emotionalism Anxiety Confusion Communication problems What is depression? Category

More information

TITLE: Dental Cleaning and Polishing for Oral Health: A Review of the Clinical Effectiveness, Cost-effectiveness and Guidelines

TITLE: Dental Cleaning and Polishing for Oral Health: A Review of the Clinical Effectiveness, Cost-effectiveness and Guidelines TITLE: Dental Cleaning and Polishing for Oral Health: A Review of the Clinical Effectiveness, Cost-effectiveness and Guidelines DATE: 24 September 2013 CONTEXT AND POLICY ISSUES Dental practitioners (dentist,

More information

Assessing study quality: critical appraisal. MRC/CSO Social and Public Health Sciences Unit

Assessing study quality: critical appraisal. MRC/CSO Social and Public Health Sciences Unit Assessing study quality: critical appraisal MRC/CSO Social and Public Health Sciences Unit Assessing study quality: why? Why critical appraise? Evidence informed decision-making assumes people make better

More information

Brief interventions for heavy alcohol users admitted to general hospital wards (Review)

Brief interventions for heavy alcohol users admitted to general hospital wards (Review) Brief interventions for heavy alcohol users admitted to general hospital wards (Review) McQueen J, Howe TE, Allan L, Mains D This is a reprint of a Cochrane review, prepared and maintained by The Cochrane

More information

Rapid Critical Appraisal of Controlled Trials

Rapid Critical Appraisal of Controlled Trials Rapid Critical Appraisal of Controlled Trials Carl Heneghan Dept of Primary Health Care University of Oxford November 23rd 2009 Five steps in EBM 1. Formulate an answerable question 2. Track down the best

More information

TREATING ASPD IN THE COMMUNITY: FURTHERING THE PD OFFENDER STRATEGY. Jessica Yakeley Portman Clinic Tavistock and Portman NHS Foundation Trust

TREATING ASPD IN THE COMMUNITY: FURTHERING THE PD OFFENDER STRATEGY. Jessica Yakeley Portman Clinic Tavistock and Portman NHS Foundation Trust TREATING ASPD IN THE COMMUNITY: FURTHERING THE PD OFFENDER STRATEGY Jessica Yakeley Portman Clinic Tavistock and Portman NHS Foundation Trust Treating the untreatable? Lack of evidence base for ASPD Only

More information

Supplementary Table 1: Risk of bias in included studies. Blinding of participants and personnel (performance bias)

Supplementary Table 1: Risk of bias in included studies. Blinding of participants and personnel (performance bias) Random sequence generation (selection bias) Allocation concealment (selection bias) Blinding of participants and personnel (performance bias) Blinding of outcome assessment (detection bias) Incomplete

More information

Q5: Is psychological debriefing better (more effective than/as safe as) than no intervention in people exposed to a recent traumatic event?

Q5: Is psychological debriefing better (more effective than/as safe as) than no intervention in people exposed to a recent traumatic event? updated 2012 Psychological debriefing in people exposed to a recent traumatic event Q5: Is psychological debriefing better (more effective than/as safe as) than no intervention in people exposed to a recent

More information

RISK ASSESSMENTS (ODARA) IN SPOUSAL / PARTNER VIOLENCE CASES FIRST ISSUED: DECEMBER 11, 2006 LAST SUBSTANTIVE REVISION: MARCH 19, 2009

RISK ASSESSMENTS (ODARA) IN SPOUSAL / PARTNER VIOLENCE CASES FIRST ISSUED: DECEMBER 11, 2006 LAST SUBSTANTIVE REVISION: MARCH 19, 2009 DOCUMENT TITLE: RISK ASSESSMENTS (ODARA) IN SPOUSAL / PARTNER VIOLENCE CASES NATURE OF DOCUMENT: PRACTICE NOTE FIRST ISSUED: DECEMBER 11, 2006 LAST SUBSTANTIVE REVISION: MARCH 19, 2009 EDITED / DISTRIBUTED

More information

Weighing the Evidence: Critical Appraisal and Systematic Review of RCTs

Weighing the Evidence: Critical Appraisal and Systematic Review of RCTs Weighing the Evidence: Critical Appraisal and Systematic Review of RCTs Dr. Rosie Mayston, Centre for Global Mental Health, Institute of Psychiatry, King s College London Overview Today s session aims

More information

Cognitive Behaviour Therapy (CBT) for family carers

Cognitive Behaviour Therapy (CBT) for family carers Dementia Action Alliance 16 th September 2014 Cognitive Behaviour Therapy (CBT) for family carers Georgina Charlesworth UCL and NEFLT with thanks to Penny Rapaport Overview of presentation What is CBT?

More information

8.2 COMPUTERISED COGNITIVE BEHAVIOURAL THERAPY WITH ONLINE DISCUSSION GROUP

8.2 COMPUTERISED COGNITIVE BEHAVIOURAL THERAPY WITH ONLINE DISCUSSION GROUP 8 EATING DISORDERS 8.1 INTRODUCTION The eating disorders include anorexia nervosa, bulimia nervosa, binge eating disorder as well as variants of these states. With the exception of binge eating disorder,

More information

PEER REVIEW HISTORY ARTICLE DETAILS TITLE (PROVISIONAL)

PEER REVIEW HISTORY ARTICLE DETAILS TITLE (PROVISIONAL) PEER REVIEW HISTORY BMJ Open publishes all reviews undertaken for accepted manuscripts. Reviewers are asked to complete a checklist review form (http://bmjopen.bmj.com/site/about/resources/checklist.pdf)

More information

Evidence-Based Nursing Practice (Infection prevention & control)

Evidence-Based Nursing Practice (Infection prevention & control) Evidence-Based Nursing Practice (Infection prevention & control) Session 3: Critical appraisal Part 1: Intro, synthesis for P&P, RCTs & Systematic reviews Feb 24, 2015 Francesca Frati, MLIS WORKSHOPS Date

More information

Q10: For carers of people with dementia, does respite care when compared to care as usual, produce benefits/harm in the specified outcomes?

Q10: For carers of people with dementia, does respite care when compared to care as usual, produce benefits/harm in the specified outcomes? updated 2012 Respite care for carers of people with dementia Q10: For carers of people with dementia, does respite care when compared to care as usual, produce benefits/harm in the specified outcomes?

More information

Form B-1. Inclusion form for the effectiveness of different methods of toilet training for bowel and bladder control

Form B-1. Inclusion form for the effectiveness of different methods of toilet training for bowel and bladder control Form B-1. Inclusion form for the effectiveness of different methods of toilet training for bowel and bladder control Form B-2. Assessment of methodology for non-randomized controlled trials for the effectiveness

More information

FA 519 : Oxygen Administration for First Aid

FA 519 : Oxygen Administration for First Aid FA 519 : Oxygen Administration for First Aid TFQO: Wei-Tien Chang COI #301 EVREV 1: Michael Nemeth COI # EVREV 2: Chih-Hung Wang COI # Taskforce: First Aid COI Disclosure (specific to this systematic review)

More information

Using Criteria to Appraise a Meta-analyses

Using Criteria to Appraise a Meta-analyses Using Criteria to Appraise a Meta-analyses Paul Cronin B.A., M.B. B.Ch. B.A.O., M.S., M.R.C.P.I.,.F.R.C.R. Department of Radiology, Division of Cardiothoracic Radiology, University of Michigan, Ann Arbor,

More information

Effectiveness of Treatment Techniques for Substance Abuse in Occupational Therapy

Effectiveness of Treatment Techniques for Substance Abuse in Occupational Therapy Pacific University CommonKnowledge Mental Health CATs OT Critically Appraised Topics 1-1-2009 Effectiveness of Treatment Techniques for Substance Abuse in Occupational Therapy Kathleen O'Day Pacific University

More information

Integrative Therapies and Preconception Health. Debbie Ringdahl DNP, RN, CNM

Integrative Therapies and Preconception Health. Debbie Ringdahl DNP, RN, CNM Integrative Therapies and Preconception Health Debbie Ringdahl DNP, RN, CNM Definitions Preconception Health primary care? CAM complementary (together with) and alternative medicine (in place of) Integrative

More information

Pastors and Domestic and Sexual Violence Survey of 1,000 Protestant Pastors

Pastors and Domestic and Sexual Violence Survey of 1,000 Protestant Pastors Pastors and Domestic and Sexual Violence Survey of 1,000 Protestant Pastors Sponsored by: Sojourners and IMA World Health 2 Methodology The telephone survey of Protestant pastors was conducted May 7-31,

More information

Critical Review: Effectiveness of cognitive stimulation therapy groups for individuals with dementia

Critical Review: Effectiveness of cognitive stimulation therapy groups for individuals with dementia Critical Review: Effectiveness of cognitive stimulation therapy groups for individuals with dementia Liza Frieri M.Cl.Sc (SLP) Candidate University of Western Ontario: School of Communication Sciences

More information

Comparative Tolerability and Harms of Individual Statins

Comparative Tolerability and Harms of Individual Statins Comparative Tolerability and Harms of Individual Statins J.J.Brugts MD PhD MSc(1); H. Naci PhD MHS(2); T. Ades PhD(2) (1) Department of Cardiology, Erasmus MC, Rotterdam, the Netherlands (2) London School

More information

Review Manager 5.1 Tutorial

Review Manager 5.1 Tutorial Review Manager 5.1 Tutorial updated February 2011 Welcome to the RevMan Tutorial. This tutorial is designed to give Cochrane review authors an introduction to the process of writing a Cochrane systematic

More information

Web appendix: Supplementary material. Appendix 1 (on-line): Medline search strategy

Web appendix: Supplementary material. Appendix 1 (on-line): Medline search strategy Web appendix: Supplementary material Appendix 1 (on-line): Medline search strategy exp Venous Thrombosis/ Deep vein thrombosis.mp. Pulmonary embolism.mp. or exp Pulmonary Embolism/ recurrent venous thromboembolism.mp.

More information

If several different trials are mentioned in one publication, the data of each should be extracted in a separate data extraction form.

If several different trials are mentioned in one publication, the data of each should be extracted in a separate data extraction form. General Remarks This template of a data extraction form is intended to help you to start developing your own data extraction form, it certainly has to be adapted to your specific question. Delete unnecessary

More information

Evidence Based Practice Information Sheets for Health Professionals. An Introduction to Systematic Reviews. This Sheet Covers the Following Concepts:

Evidence Based Practice Information Sheets for Health Professionals. An Introduction to Systematic Reviews. This Sheet Covers the Following Concepts: Supplement 1, 2001 ChangingPractice Evidence Based Practice Information Sheets for Health Professionals An Introduction to Systematic Reviews The series Changing Practice has been designed to support health

More information

Moderate Drinking, Harm Reduction, and Abstinence Outcomes

Moderate Drinking, Harm Reduction, and Abstinence Outcomes Moderate Drinking, Harm Reduction, and Abstinence Outcomes BACKGROUND Kenneth Anderson - HAMS Harm Reduction Starting in the 1970s and leading up to the present day, William Miller and his colleagues have

More information

CAGE. AUDIT-C and the Full AUDIT

CAGE. AUDIT-C and the Full AUDIT CAGE In the past have you ever: C tried to Cut down or Change your pattern of drinking or drug use? A been Annoyed or Angry because of others concern about your drinking or drug use? G felt Guilty about

More information

UNDERSTANDING CLINICAL TRIAL STATISTICS. Prepared by Urania Dafni, Xanthi Pedeli, Zoi Tsourti

UNDERSTANDING CLINICAL TRIAL STATISTICS. Prepared by Urania Dafni, Xanthi Pedeli, Zoi Tsourti UNDERSTANDING CLINICAL TRIAL STATISTICS Prepared by Urania Dafni, Xanthi Pedeli, Zoi Tsourti DISCLOSURES Urania Dafni has reported no conflict of interest Xanthi Pedeli has reported no conflict of interest

More information

Critical Appraisal of a Randomized Trial

Critical Appraisal of a Randomized Trial Critical Appraisal of a Randomized Trial Presented by Brian S. Alper, MD, MSPH, FAAFP Founder of DynaMed; Vice President of Evidence-Based Medicine Research and Development, Quality and Standards Introduction

More information

Pharmacological interventions for drug-using offenders (Review)

Pharmacological interventions for drug-using offenders (Review) Pharmacological interventions for drug-using offenders (Review) Perry AE, Neilson M, Martyn-St James M, Glanville JM, McCool R, Duffy S, Godfrey C, Hewitt C This is a reprint of a Cochrane review, prepared

More information

Preparing Summary of Findings tables for Cochrane Reviews

Preparing Summary of Findings tables for Cochrane Reviews Preparing Summary of Findings tables for Cochrane Reviews Introduction Translating and presenting numbers GRADEing the evidence Applicability and Recommendations Methods Group (schuneh@mcmaster.ca) Content

More information

Session 5: How to critically appraise a paper an example

Session 5: How to critically appraise a paper an example Session 5: How to critically appraise a paper an example Appraising research broad questions l What is the research question? l Is the study ethical? l Is the study design valid and appropriate? l What

More information

SIGN CRITICAL APPRAISAL COURSE: EXERCISE 2

SIGN CRITICAL APPRAISAL COURSE: EXERCISE 2 SIGN CRITICAL APPRAISAL COURSE: EXERCISE 2 This presentation shows s one individuals id assessment of the RCT used in the second exercise. It links back to sections of the paper in the same way that we

More information

Critical Appraisal of a Randomized Controlled Trial Are the Results of the Study Valid?

Critical Appraisal of a Randomized Controlled Trial Are the Results of the Study Valid? Critical Appraisal of a Randomized Controlled Trial Are the Results of the Study Valid? Objectives: 1. Compare and contrast observational and experimental studies. 2. Define study population and inclusion

More information

Effectiveness of Case Management in Treating Substance Abusers Selected Results from a Metaanalysis Richard C. Rapp, M.S.W. Center for Interventions, Treatment, and Addictions Research Boonshoft School

More information

Acute Migraine Treatment in Emergency Settings: A systematic review and mixed treatment comparison.

Acute Migraine Treatment in Emergency Settings: A systematic review and mixed treatment comparison. Acute Migraine Treatment in Emergency Settings: A systematic review and mixed treatment comparison. Brian H. Rowe, MD, MSc, CCFP(EM) Tier 1 Canada Research Chair in Evidence-based Emergency Medicine Professor,

More information

Prepared by:jane Healey (Email: janie_healey@yahoo.com) 4 th year undergraduate occupational therapy student, University of Western Sydney

Prepared by:jane Healey (Email: janie_healey@yahoo.com) 4 th year undergraduate occupational therapy student, University of Western Sydney 1 There is fair (2b) level evidence that living skills training is effective at improving independence in food preparation, money management, personal possessions, and efficacy, in adults with persistent

More information

Motivational interviewing for substance abuse

Motivational interviewing for substance abuse Campbell Systematic Reviews 2011:6 First published: 29 August, 2011 Last updated: 27 March, 2011 Motivational interviewing for substance abuse Geir Smedslund, Rigmor C. Berg, Karianne T. Hammerstrøm, Asbjørn

More information

Motivational interviewing for substance abuse (Review)

Motivational interviewing for substance abuse (Review) Smedslund G, Berg RC, Hammerstrøm KT, Steiro A, Leiknes KA, Dahl HM, Karlsen K This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane

More information

HEALTHLINES STUDY RANDOMISED CONTROLLED TRIAL PROTOCOL SUMMARY

HEALTHLINES STUDY RANDOMISED CONTROLLED TRIAL PROTOCOL SUMMARY HEALTHLINES STUDY RANDOMISED CONTROLLED TRIAL PROTOCOL SUMMARY VERSION 1.0, 30 MAY 2012 Effectiveness and cost-effectiveness of a NHS Direct-delivered telehealth intervention to support the management

More information

EVALUATION/PRIORITIZATION CRITERIA: C, L, R, S *to meet requirement 1

EVALUATION/PRIORITIZATION CRITERIA: C, L, R, S *to meet requirement 1 COMPENDIA TRANSPARENCY TRACKING FORM DATE: MAY 2015 PACKET: 111 DRUG: INDICATION: Vinorelbine Tartrate Malignant pleural mesothelioma COMPENDIA TRANSPARENCY REQUIREMENTS 1 Provide criteria used to evaluate/prioritize

More information

Experimental (quantitative) studies: An overview and general issues by Stephanie Tierney

Experimental (quantitative) studies: An overview and general issues by Stephanie Tierney Experimental (quantitative) studies: An overview and general issues by Stephanie Tierney (stephanie.tierney@manchester.ac.uk) Experimental designs are said to be the approach for obtaining information

More information

What is critical appraisal?

What is critical appraisal? ...? series Second edition Evidence-based medicine Supported by sanofi-aventis What is critical appraisal? Amanda Burls MBBS BA MSc FFPH Director of the Critical Appraisal Skills Programme, Director of

More information

Can I have FAITH in this Review?

Can I have FAITH in this Review? Can I have FAITH in this Review? Find Appraise Include Total Heterogeneity Paul Glasziou Centre for Research in Evidence Based Practice Bond University What do you do? For an acutely ill patient, you do

More information

BEST in MH clinical question-answering service

BEST in MH clinical question-answering service Best Evidence Summaries of Topics in Mental Healthcare BEST in MH clinical question-answering service Question In people with PTSD (including single and multiple event trauma) how effective is prazosin

More information

Randomization in Clinical Trials

Randomization in Clinical Trials in Clinical Trials Versio.0 May 2011 1. Simple 2. Block randomization 3. Minimization method Stratification RELATED ISSUES 1. Accidental Bias 2. Selection Bias 3. Prognostic Factors 4. Random selection

More information

ESPEN Congress Cannes Education and Clinical Practice Programme

ESPEN Congress Cannes Education and Clinical Practice Programme ESPEN Congress Cannes 2003 Organised by the Israel Society for Clinical Nutrition Education and Clinical Practice Programme Session: Pharmacist Session: Amino Acids Branched Chain Amino Acids for Hepatic

More information

Twin Cities Healthy Start Pregnancy Psychosocial Risk Screening Validation Study

Twin Cities Healthy Start Pregnancy Psychosocial Risk Screening Validation Study Twin Cities Healthy Start Pregnancy Psychosocial Risk Screening Validation Study Amy Godecker, Ph.D. Stacye Ballard, B.A. Minneapolis Department of Health and Family Support 1 Background and context for

More information

SUPPLEMENTARY GUIDANCE FOR AUTHORS

SUPPLEMENTARY GUIDANCE FOR AUTHORS SUPPLEMENTARY GUIDANCE FOR AUTHORS UNDERTAKING REVIEWS WITH THE COCHRANE CONSUMERS AND COMMUNICATION REVIEW GROUP Welcome to the Cochrane Consumers and Communication Review Group (CC&CRG) supplementary

More information

Brief Intervention to Reduce Injuries in Minorities National Institute on Alcohol Abuse and Alcoholism R01-AA-013824 (PI: Caetano)

Brief Intervention to Reduce Injuries in Minorities National Institute on Alcohol Abuse and Alcoholism R01-AA-013824 (PI: Caetano) Craig A. Field, PhD, MPH Gerald Cochran The University of Texas at Austin Health Behavioral Research and Training Institute Raul Caetano, MD, PhD UT Southwestern Medical Center Brief Intervention to Reduce

More information

Outline. Publication and other reporting biases; funnel plots and asymmetry tests. The dissemination of evidence...

Outline. Publication and other reporting biases; funnel plots and asymmetry tests. The dissemination of evidence... Cochrane Methodology Annual Training Assessing Risk Of Bias In Cochrane Systematic Reviews Loughborough UK, March 0 Publication and other reporting biases; funnel plots and asymmetry tests Outline Sources

More information

EBM Cheat Sheet- Measurements Card

EBM Cheat Sheet- Measurements Card EBM Cheat Sheet- Measurements Card Basic terms: Prevalence = Number of existing cases of disease at a point in time / Total population. Notes: Numerator includes old and new cases Prevalence is cross-sectional

More information

Effectiveness of brief alcohol interventions in primary care populations (Review)

Effectiveness of brief alcohol interventions in primary care populations (Review) Effectiveness of brief alcohol interventions in primary care populations (Review) Kaner EF, Dickinson HO, Beyer FR, Campbell F, Schlesinger C, Heather N, Saunders JB, Burnand B, Pienaar ED This is a reprint

More information

Addendum to clinical guideline 28, depression in children and young people

Addendum to clinical guideline 28, depression in children and young people : National Institute for Health and Care Excellence Final Addendum to clinical guideline 28, depression in children and young people Clinical guideline addendum 28. Methods, evidence and recommendations

More information

Introduction to study design

Introduction to study design Introduction to study design Doug Altman EQUATOR Network, Centre for Statistics in Medicine, NDORMS, University of Oxford EQUATOR OUCAGS training course 4 October 2014 Objectives of the day To understand

More information

Advances in Psychological Treatments for Adult ADHD

Advances in Psychological Treatments for Adult ADHD Advances in Psychological Treatments for Adult ADHD Dr Antonia Dittner Senior Clinical Psychologist Maudsley Adult ADHD Service antonia.dittner@slam.nhs.uk The need for a multidisciplinary approach to

More information

Q6: Should non-specialist health care providers refer alcohol dependent patients and their family members to mutual help groups such as AA?

Q6: Should non-specialist health care providers refer alcohol dependent patients and their family members to mutual help groups such as AA? Q6: Should non-specialist health care providers refer alcohol dependent patients and their family members to mutual help groups such as AA? Background Self help groups such as Alcoholics Anonymous (AA)

More information

Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies

Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies Page 1 of 5 Browse» Regulatory: Regulatory» Review» Individual Studies Pharmaceutical policies: effects of, other pricing, and purchasing policies Aaserud M, Dahlgren AT, Kosters JP, Oxman AD, Ramsay C,

More information

Patient Reported Outcomes

Patient Reported Outcomes Patient Reported Outcomes 16 December 2013, Nottingham Esther van Zuuren Dermatologist, Leiden University Medical Centre Netherlands Patient Reported Outcomes A Patient Reported Outcome (PRO): any aspect

More information

Professor Keith Hill, School of Physiotherapy and Exercise Science Curtin University Keith.Hill@Curtin.edu.au

Professor Keith Hill, School of Physiotherapy and Exercise Science Curtin University Keith.Hill@Curtin.edu.au Professor Keith Hill, School of Physiotherapy and Exercise Science Curtin University Keith.Hill@Curtin.edu.au Curtin University is a trademark of Curtin University of Technology CRICOS Provider Code 00301J

More information

Data Extraction and Quality Assessment

Data Extraction and Quality Assessment Data Extraction and Quality Assessment Karen R Steingart, MD, MPH Francis J. Curry International Tuberculosis Center University of California, San Francisco Berlin, 12 November 2010 karenst@uw.edu The

More information

A COMPARISON OF TWO TECHNIQUES TO REACH RELATIVES OF ALCOHOLICS FOR INFORMATION OF AVAILABLE SUPPORT

A COMPARISON OF TWO TECHNIQUES TO REACH RELATIVES OF ALCOHOLICS FOR INFORMATION OF AVAILABLE SUPPORT Alcohol & Alcoholism Vol. 31, No. 4, pp. 359-363, 1996 A COMPARISON OF TWO TECHNIQUES TO REACH RELATIVES OF ALCOHOLICS FOR INFORMATION OF AVAILABLE SUPPORT ULLA ZETTERLIND*, MATS BERGLUND and KIRSTEN ABERG-ORBECK

More information

Supplementary Online Content

Supplementary Online Content Supplementary Online Content Di Bona D, Plaia A, Leto-Barone MS, La Piana S, Di Lorenzo G. Efficacy of grass pollen allergen sublingual immunotherapy tablets for seasonal allergic rhinoconjunctivitis:

More information

Current reporting in published research

Current reporting in published research Current reporting in published research Doug Altman Centre for Statistics in Medicine, Oxford, UK and EQUATOR Network Research article A published research article is a permanent record that will be used

More information

Training Health Care Practitioners for Texas and Georgia SBIRT: Standardized Patient and Expert Coaching Models

Training Health Care Practitioners for Texas and Georgia SBIRT: Standardized Patient and Expert Coaching Models Training Health Care Practitioners for Texas and Georgia SBIRT: Standardized Patient and Expert Coaching Models Mary M. Velasquez, Ph.D. 1 Sylvia Shellenberger, Ph.D. 2 Kirk von Sternberg, Ph.D. 1 1 University

More information

Critical Appraisal of a Research Paper

Critical Appraisal of a Research Paper Critical Appraisal of a Research Paper Andrew MacInnes, BDS (Hons.) MFDS, RCPS (Glasgow), Senior House Officer 1 Thomas Lamont, BDS, MFDS, RCPS (Glasgow), Clinical Research Fellow/Honorary Restorative

More information

The Campbell Collaboration www.campbellcollaboration.org. Study content coding Effect size coding (next session)

The Campbell Collaboration www.campbellcollaboration.org. Study content coding Effect size coding (next session) Systema(c Review Methods Workshop Study Coding Sandra Jo Wilson Vanderbilt University Editor, Campbell Collabora9on Educa9on Coordina9ng Group Workshop Overview Levels of Study Coding Study eligibility

More information

Q8. Should Anti-Epileptic Drug (AED) treatment be started after first unprovoked seizure in non-specialist health settings?

Q8. Should Anti-Epileptic Drug (AED) treatment be started after first unprovoked seizure in non-specialist health settings? updated 2012 Antiepileptic drug treatment after first unprovoked seizure Q8. Should Anti-Epileptic Drug (AED) treatment be started after first unprovoked seizure in non-specialist health settings? Background

More information

Protocol registration and outcome reporting bias in randomised controlled trials of

Protocol registration and outcome reporting bias in randomised controlled trials of Title: Protocol registration and outcome reporting bias in randomised controlled trials of eczema treatment Rationale: As one of the measures to reduce the likelihood of selective reporting bias in RCTs,

More information

Formulating the Review Question & Writing a Protocol

Formulating the Review Question & Writing a Protocol Formulating the Review Question & Writing a Protocol Madhukar Pai, MD, PhD Associate Professor Department of Epidemiology & Biostatistics McGill University, Montreal, Canada Email: madhukar.pai@mcgill.ca

More information

Couple Therapy ROLE OF BEHAVIORAL COUPLE THERAPY IN TREATMENT OF SUBSTANCE USE DISORDERS MYRTO MIA MCNEIL, RN, BSN,DNP (C)

Couple Therapy ROLE OF BEHAVIORAL COUPLE THERAPY IN TREATMENT OF SUBSTANCE USE DISORDERS MYRTO MIA MCNEIL, RN, BSN,DNP (C) Couple Therapy ROLE OF BEHAVIORAL COUPLE THERAPY IN TREATMENT OF SUBSTANCE USE DISORDERS MYRTO MIA MCNEIL, RN, BSN,DNP (C) Learning Objectives At the end of this presentation the participant will be able

More information

TITLE: Fall Prevention in Adults with Mental Health and Substance Use Needs: A Review of the Clinical Evidence and Guidelines

TITLE: Fall Prevention in Adults with Mental Health and Substance Use Needs: A Review of the Clinical Evidence and Guidelines TITLE: Fall Prevention in Adults with Mental Health and Substance Use Needs: A Review of the Clinical Evidence and Guidelines DATE: 11 January 2012 CONTEXT AND POLICY ISSUES: Approximately 30 to 40 percent

More information

Excellence in Prevention descriptions of the prevention programs and strategies with the greatest evidence of success

Excellence in Prevention descriptions of the prevention programs and strategies with the greatest evidence of success Name of Program/Strategy: Brief Alcohol Screening and Intervention for College Students (BASICS) Report Contents 1. Overview and description 2. Implementation considerations (if available) 3. Descriptive

More information

Treatment of seizures in multiple sclerosis (Review)

Treatment of seizures in multiple sclerosis (Review) Koch MW, Polman SKL, Uyttenboogaart M, De Keyser J This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 009, Issue 3 http://www.thecochranelibrary.com

More information

Teen-Intervene Using Brief Intervention with Substance-Abusing Adolescents From HAZELDEN A Research-based Program

Teen-Intervene Using Brief Intervention with Substance-Abusing Adolescents From HAZELDEN A Research-based Program Teen-Intervene Using Brief Intervention with Substance-Abusing Adolescents From HAZELDEN A Research-based Program What is Teen-Intervene? Teen-Intervene is a tested, time-efficient, evidence-based program

More information

Motivational Interviewing for Binge Eating Disorder. Stephanie E. Cassin, Ph.D., C.Psych.

Motivational Interviewing for Binge Eating Disorder. Stephanie E. Cassin, Ph.D., C.Psych. Motivational Interviewing for Binge Eating Disorder Stephanie E. Cassin, Ph.D., C.Psych. Motivational Interviewing (MI) Developed in the field of addictions Based on the Stages of Change model A non-confrontational

More information

A Multi-Centre Efficacy Trial of Naltrexone Maintenance Therapy in Hong Kong

A Multi-Centre Efficacy Trial of Naltrexone Maintenance Therapy in Hong Kong A Multi-Centre Efficacy Trial of Naltrexone Maintenance Therapy in Hong Kong Executive Summary 1. Study Background 1.1 In May 1999, upon the recommendations of the Action Committee Against Narcotics (ACAN)

More information

Socioeconomic Value of the Midwife. A systematic review, meta-analysis, meta-synthesis and economic analysis of midwife-led models of care

Socioeconomic Value of the Midwife. A systematic review, meta-analysis, meta-synthesis and economic analysis of midwife-led models of care Socioeconomic Value of the Midwife A systematic review, meta-analysis, meta-synthesis and economic analysis of midwife-led models of care Executive Summary Declan Devane 1, Miriam Brennan 1, Cecily Begley

More information

Behavioral couples therapy for drug-abusing patients: effects on partner violence

Behavioral couples therapy for drug-abusing patients: effects on partner violence Journal of Substance Abuse Treatment 22 (2002) 87 96 Regular article Behavioral couples therapy for drug-abusing patients: effects on partner violence William Fals-Stewart, Ph.D. a, *, Todd B. Kashdan,

More information

MIND-BODY THERAPIES FOR HYPERTENSION

MIND-BODY THERAPIES FOR HYPERTENSION MIND-BODY THERAPIES FOR HYPERTENSION Systematic Review and Meta-Analysis Ather Ali, ND, MPH (1), David L. Katz, MD, MPH (1,2), Michael B. Bracken, PhD, MPH (2). (1)Yale-Griffin Prevention Research Center

More information

An Introduction to the Critical Appraisal Section (including example questions)

An Introduction to the Critical Appraisal Section (including example questions) An Introduction to the Critical Appraisal Section (including example questions) Introduction This section is common to the specialties of Dental Public Health, Oral Medicine, Oral Surgery, Orthodontics,

More information

Pilot study: Testing an online alcohol intervention in primary care

Pilot study: Testing an online alcohol intervention in primary care Pilot study: Testing an online alcohol intervention in primary care Natasha Nair 1,2, Maree Teesson 1,2, Anthony Shakeshaft 1, Nicola Newton 1,2 & Paul Wallace 3 1 National Drug and Alcohol Research Centre,

More information

BEST in MH clinical question-answering service

BEST in MH clinical question-answering service Best Evidence Summaries of Topics in Mental Healthcare BEST in MH clinical question-answering service Question In adults with a diagnosis of psychotic / delusional depression how effective is electroconvulsive

More information

Practical examples [& pitfalls] of addressing bias in child treatment trials

Practical examples [& pitfalls] of addressing bias in child treatment trials Practical examples [& pitfalls] of addressing bias in child treatment trials Dr Matt Woolgar Consultant Clinical Psychologist & Senior Researcher National Academy for Parenting Research Quality of Measures

More information

Q4: Are acamprosate, disulfiram and naltrexone safe and effective in preventing relapse in alcohol dependence in nonspecialized health care settings?

Q4: Are acamprosate, disulfiram and naltrexone safe and effective in preventing relapse in alcohol dependence in nonspecialized health care settings? updated 2012 Preventing relapse in alcohol dependent patients Q4: Are acamprosate, disulfiram and naltrexone safe and effective in preventing relapse in alcohol dependence in nonspecialized health care

More information

Study Design for Chemoprevention. Cancer Epidemiology, Prevention and Control Workshop Shanghai, March 12, 2008

Study Design for Chemoprevention. Cancer Epidemiology, Prevention and Control Workshop Shanghai, March 12, 2008 Study Design for Chemoprevention Cancer Epidemiology, Prevention and Control Workshop Shanghai, March 12, 2008 I. INTRODUCTION Experimental studies are conducted to assess the effect of a treatment using

More information