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1 Provocation tests for intoxication with Heavy s. Patient / ales = Heavy s Diaval-test nanool / litre 1# Copper icrool / 24 hr. 2# AK * f PD Cu,Hg ,1 5,7 16, , Yes? Yes /? AO 1996 PD 1 9 0,1 1, No - Yes /? BF * 2007 PD Cu,Hg , , Yes No Yes / No CK f 1999 PD Cu,Hg ,5 0,3 6,9 3, Yes No Yes / No CL 1996 PD Cu ,1 5,5 10, Partiel Yes? Yes /? DV 2001 PD Cu,Hg ,1 9,4 3, Yes No Yes / No DY * f 2001 PD Cu,Hg , , Yes Yes Yes / No EH 2003 PD Cu,Hg ,2 5, Yes No No / Yes FE f 2002 PD Cu,Hg ,1 5, No - Yes / Yes FI f 2001 PD Cu,Hg ,3 22,6 7, Yes? Yes /? JC * f 2006 PD Cu,Hg ,1 4, No? No /? HA f 2009 PD Cu,Hg ,2 15,6 7, Yes No Yes / No HBO 2005 PD Cu,Hg ,2 9, ? Yes Yes Yes / Yes OH 2007 PD Cu,Hg ,2 23,8 6, Yes No Yes / No OO * f 2010 PD Cu ,1 6, Yes - No / HJ 2001 PD Cu,Hg ,1 8, No? Yes / No JL f 2002 PD Cu,Hg ,9 5, Partiel Yes Yes /? KI f 2008 PD Cu,Hg ,3 13, Yes? Yes / No KH * f 1998 PD Cu,(Pb,Al) 6* ,1 3,1 3, Yes Yes Yes / Yes NL * 1995 PD ,1 2?? ?? No - - NR 2004 PD Cu,Hg ,4 9,9 16, Yes No Yes / Yes PU * f 2004 PD Cu,Hg , 2 6, No - Yes / No RK * f 6# 2009 PD Cu 1, ,2 4,0 2, Yes - Yes / No HO * 2003 PD Cu,Hg ,1 28, No - No / SB * f 7# 2005 PD Cu,Hg No No No /? SE f 2004 PD Cu ,5 8,8 3, Yes Yes Yes / No SG f 1998 PD Cu ,4 18,6 18, ? 2008 Yes Yes 11# Yes / Yes SS 2000 PD Cu,Hg ,1 9,6 8, No? Yes /? SSB * f 2000 PD Cu ,2 6, No Yes / No VU 2007 PD Cu,Hg ,5 6,6 5, Yes Yes No / No WN 2002 PD Cu ,2 10, No No Yes /?

2 ales = Heavy s Diaval-test µg / g creatinine 3# Copper µg / g creatinine 4# RK *f 6# 2009 PD Cu,Hg,Pb,Cd,Sb , Yes - Yes / No SF * 13# 2009 PD Cu,Hg , Yes - Yes /? HA f 2009 PD Cu,Hg,Sb , Yes No Yes / No

3 ales = Heavy s Atair-test µg / g creatinine 3# Copper µg / g creatinine 4# AJ f 2008 PD Cu,Pb 1,0 1, , No No / BH * 2005 PD Cu,Pb 1, ,001 1, Yes No Yes / No DA f 2001 PD? - 2, No - Yes / Yes EY f 1999 PD Cu,Hg,Pb 1,6 3,8 Not done 0, No Yes Yes / No EK * 2009 PD Cu 0,7 1,6 0,007 0, No? Yes / No GA f 1990 PD Cu,Hg - 4,6 0,017 0, Yes - No /? HH * f 2010 PD Cu,PB,Ba,Cs 3, ,1 O,013 0,5 0, Yes? No /? HL * f PD Cu,Hg,Pb 4 6,4 2,7 0,010 0, Yes JC * f 2005 PD Cu,Pb <dl 0,5 Not done 1, Yes JH * 2008 PD Cu,Hg, Al,As,Ni 1,3 3,0 2,0 0,006 0,66 0, Yes No Yes / No JI f 2003 PD Cu,Hg 1,1 4,6 2,3 Not done 0,85 0, No No Yes / No JNO 2007 PD Cu, Cd 0,9 1,3 0,7 0,011 0,63 0, Yes No Yes / No KE * f 1998 PD Cu 0,3 0,6 Not done 0, No - No / No KHe f 2004 PD Cu, Hg, Pb, 4,4 6,4 4, ,47 0, Yes - Yes / No KJ * f 2004 PD Cu, As 2,5 0,9 3,4 0,014 0,82 0, Yes No Yes / No LI * f 2009 PD Cu,Pb,Cs,Th,Tl, 0,9 1,9 0, Yes? - Yes / W LEN * 2004 PD Cu,Hg,Pb,Ni,Th 1,5 4,5 3,6 0,008 0,47 0, Yes No No / Yes MA * f 8# 2007 PD Cu,? 0,4 0.9 Not done 0,46 0, Yes No No MU * f 15# 2010 PD Cu,Pb,Ba, Gd 3.9 1,5 2,6 Not done 1,2 0, Yes Yes Yes /? OG * f 1997 PD Cu,Hg 4,9 3,1 4,9 Not done 0,413 0, Yes No Yes PA f 1999 PD Cu,Pb 1,2 3,1 Not done 1, Yes - No SEL 2006 PD Cu,Hg,Pb 1,2 2,1 0,5 0,009 0,424 0, Yes? Yes / Yes SI * f 2009 PD Cu,Hg,Pb,Ba,Ce Not done 2,5 3,7 Not done 0,58 0, Yes? Yes /? VU 2007 PD Cu, Hg,Pb 14# - 1,9 3,4 - Not done 0, Yes? Yes /? ZS * f 2004 PD Cu 0,7 1,5 1,5 0,002 0,58 0, Yes No No / No

4 ales = Heavy s DMSA-test µg / g creatinine 3 # Copper g / g creatinine 4 # health CM * f 2005 PD Hg,Pb Not done 6,7 Not done Not done Yes Yes Yes / DV 2001 PD Hg,Pb Not done 3,6 Not done 0, Yes No Yes / No EH 2003 PD Hg,Cu,Pb,Cs,W, Not done 4,1 Not done 0, Yes No No/ Yes U HK 2003 PD Cu,Hg,Pb 10# Not done 7 Not done 0, Yes Yes Yes / Yes KH * f 1998 PD (Cu),Pb,Al,Ba Not done 2,6 3,8 Not done 0,064 0, Yes Yes Yes / Yes NB f 2002 PD Hg,Pb Not done 9,4 Not done No No Yes / No NT * PD As,Cd,Pb,Ni,TI Not done 0,7 Not done 0, No No Yes / - QK f 2005 PD As,Pb,Th Not done 2,7 Not done 0, Yes? Yes / No WV 2005 PD As,Ba,Cd,Cs,Pb, TI 0,9 1,8 0,9 0,01 0, Yes Yes Yes /?

5 Cu Hg Pb PD PD+ = Cobber- intoxication / - elevated = intoxication / -elevated = Lead intoxication / -elevated = Parkinson disease = Parkinson Plus disease Patients tested with Diaval are norally tested for and Copper only. 1# Note: Reference ranges 5-82 nanool / litre. 250 nanool / litre are absolutely a heavy intoxication. No lowest level is safe. (Ref. Range can be discussed). 2# Note: Reference ranges 0,1 1,3 icro ol / 24 hr. Chelated test ust be < 3,0 icro ol / 24 hr (Ref. Range can be discussed). 3# Note: Reference ranges < 3 µg / g creatinine. No lowest level is safe. 4# Note: Reference ranges µg / g creatinine. (Ref. Range can be discussed.) 5# Note: No patients, except SG and DA, have claied to get syptos when using safe reoval aalga by the rules recoended by IAOMT. 6# Note: The patient have been though soe treatent with chelating Agent before the chelating test. Test shows intoxication with Sb, Cs, Pt and TI too. 7# Note: Pre-test ercury 1,1 µg Hg / g creatinine. Post-test ercury 49 µg Hg / g creatinine. Post-test copper 431 µg / g creatinine. 8# Note: Test 1. and 2. done by noral doctor with subnoral dose Atair (750 g.). The test result indicates intoxication with copper. High in Nickel. 9# Note: Patient TA is acute intoxicated with and that is why the patient is not testes with. Copper is tested the ,6 µol / litre which is within reference ranges 10# Note: Urine saples collected 6 hours and not 24 hours as stated to the laboratory. 11# Note: Planed operation for PD has been cancelled after health iprove. 12# Note: Repeat test with fresh saple is recoended. 13# Note: Urine saple collected 6 hours 14# Note: The patient is intoxicated with several other heavy etals too. As, Be, Cs, Th. 15# Note: Gadoliniu pretest 70 µg / g creatinine. Posttest 50 µg / g creatinine Test urine collected only 16 hours. Patients tested with ore than one Agent: KH, HK, VU and NB In patients SEL and KH intoxication / elevated levels Aluiniu see to poop up after several treatents with. Pre- and Post-test is norally done the sae day or within few days The level or Copper could be fluctuating. This eans that the lowest level is not always the latest level. But in ost cases the level the Heavy s are decreased when treated. Note that the patient also could be re-intoxicated. Copper is said to be chelated before other heavy etals as ex. and Lead, which eans that a high level Copper could ask a higher level (or Lead) than seen.

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