What s New! A report to CASC, 2004

Transcription

1 What s New! A report to CASC, 2004 Michael J. Ackerman, Ph.D. Assistant Director High Performance Computing and Communications National Library of Medicine

2 Healthcare and the Next Generation Internet The National Library of Medicine (NLM) is funding test-bed projects to demonstrate the use of NGI capabilities by the health community. These capabilities include: Quality of Service Security and medical data privacy Nomadic computing Network management Infrastructure technology as a means for collaboration The demonstrations are designed to improve our understanding of the impact of NGI capabilities on the nation s healthcare, health education, and health research systems in such areas as cost, quality, usability, efficacy and security.

3 Telemammography for the Next Generation Internet, Phase II: The National Digital Mammography Archive Provide a means to store and retrieve a complete clinical record, consisting of digital, mammographic images as well as radiology and pathology reports and related patient information in standard formats and using standard protocols Multi-layered security Input and retrieval from multiple locations University of Pennsylvania, Philadelphia, PA Y12 National Security Complex in Oak Ridge, Oak Ridge, TN University of Chicago, Chicago, IL University of North Carolina at Chapel Hill, Chapel Hill, NC University of Toronto, Toronto, Canada

4 Radiation Oncology Treatment Planning/Care Delivery Application Develop, implement, and evaluate NGI capabilities for radiation oncology treatment planning and care delivery. Application will provide diagnostic support, treatment planning, and remote verification of equipment from Cancer Center to a remote treatment facility. Focus on quality of service, security, privacy, and data integrity. Johns Hopkins University Applied Physics Laboratory, Laurel, MD Peninsula Regional Medical Center, Salisbury, MD

5 A Multicenter Clinical Trial Using NGI Technology Test the network infrastructure capable of high speed transmission of high quality MRI images for a multicenter clinical trial of new therapies for adrenoleukodystrophy (ALD), a fatal neurologic genetic disorder Ensure medical data privacy and security. Kennedy Krieger Research Institute, Baltimore, MD

6 Remote, Real-time Simulation for Teaching Human Anatomy and Surgery Demonstrate remote, real-time teaching of human anatomy and surgery Deliver real-time simulation and visualization technologies Network-based architecture will allow for multiple highresolution stereo-graphic displays and haptic devices Stanford University School of Medicine Stanford, CA

7 An NGI Program Lesson QoS... can completely and correctly be implemented only with the knowledge and help of the application standing at the endpoints of the communications systems. Therefore, providing that questioned function as a feature of the communications systems itself is not possible. Marjory Blumenthal and David Clark, ACM Transactions on Internet Technology

8 Workshop on New Visions for Large-Scale Networks: Research and Applications March 12-14, 2001 Adaptive, dynamic, and smart networking Automated discovery of resources Measurement, simulation, modeling, and scalability End to end performance measurement and metrics Trust (security, privacy, and reliability) Quality of Service Middleware Prototype networks and applications Collaboration environments Revisiting network fundamentals Wireless technology

9 Applications of Advanced Network Infrastructure Technology in Health and Disaster Management Applications demonstrating self-scaling technology Applications utilizing self-optimizing end-to-end network aware real-time technology and/or middleware Applications dependent on wireless technology Applications which involve advanced authentication methodologies, e.g. biometrics or smartcards Nomadic technology applications and/or applications using geographic information systems (GIS) techniques

10 NLM Sponsored SII Projects 3D Telepresence for Medical Consultation University of North Carolina, Chapel Hill An Adaptive, Scalable, and Secure I2-based Client-Server Architecture for Interactive Analysis and Visualization of Volumetric-Time Series Data Carnegie Mellon University Wireless Internet Information System for Medical Response in Disasters University of California, San Diego

11 With Next Generation Networking...

12 The National Library of Medicine s Software Vision Create a dynamic, self-sustaining, public domain and extensible toolkit that will empower researchers throughout the world to develop new segmentation and registration algorithms and create new applications that leverage the NLM s investment in the Visible Human Male and Female data sets

13 Segmentation & Registration Tool Kit: ITK Tool Kit: ITK Open Source Image Segmentation multivalued (multimodal) data Image Registration rigid and deformable registration Validation Generation of mathematical models as test data Acquisition of validation datasets from medical scanners

14 What is Insight (ITK)? A common Application Programmers Interface (API). A framework for software development A toolkit for registration and segmentation An Open Source resource for future research A validation model for segmentation and registration. A framework for validation development A seed repository for validated segmentations Assistance for algorithm designers

15 Why Open? Protect software investment of funding organizations Objective peer review Software outlives the developer Higher interoperability Access to a pool of developers that know the code Mix between custom and COTS code High quality software is possible

16 Open Software Open API s OpenGL DICOM Java Open Source Emacs Apache Linux OpenDX vxl, Computer Vision Library Cgal, Computational geometry Slicer, surgical planning vtk, Visualization Toolkit

17 Openness From the start, NLM recognized the value of Open Source software There are NO restrictions on the software The Team has embraced openness

18 The Insight Software Consortium The purpose of computing is insight,, not numbers. - Hamming

19 The Insight Toolkit - ITK Release 1.4

20 Documentation ITK Software Guide Hyperlinked PDF available on-line Printed version as well (Kitware commercial product) ITK Theory Book On its way

21 Insight Toolkit About 400 C++ classes About 300,000 lines of code in the Toolkit 34,000 cvs comments by 36 developers Two mailing lists 200

22 Insight - Open Source Products

23 CMake Platform independent makefile generation Unix/Linux/Cygwin Microsoft Ver.6/Ver. 7 C++ Intel C++ Borland C++ Simplifies the build process Auto-configuration Easy access to external libraries Used by several other Open Source Projects

24 CABLE Wrapping package Automatic generation of bindings to C++ classes for use in interpreted languages Uses GCC-XML, an extension to GCC Currently wraps Insight into TCL

25 DART Dashboard generator Coordinates builds and tests from multiple sources Client produces build/test results in XML Server converts XML to HTML web pages Supports continuous build process

26 Extreme Programming Compression of standard analyze, design, implement, test cycle into a continuous process

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28 Someone broke the build!

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30 Interventional Radiology: 3D Ultrasound Annotation Fuse pre-operative MR/CT with intra-operative US for surgical guidance seconds

31 Haptics for Surgical Training Microsoft: Mark Foskey Scan to simulation : 1 hour

32 ITK in use ITK in Analyze 6.0 from the Mayo Clinic Imperial College of London contributing registration algorithms ITK in a surgical planning workstations being developed at Georgetown Medical School Harvard Medical School adopting ITK Carnegie Mellon Robotics Institute teaching computer vision using ITK

33 National Library of Medicine