The Incidence of Malignant Mesothelioma Australia

Size: px
Start display at page:

Download "The Incidence of Malignant Mesothelioma Australia 1982-1988"

Transcription

1 American Journal of Industrial Medicine 20: (1991) The Incidence of Malignant Mesothelioma Australia in James Leigh, MB, BS, MSc, MA, PhD, Carlos F. Corvalan, MA, Ashraf Grimwood, MB, ChB, Geoffrey Berry, MA, PhD, David A. Ferguson, MD, and Rebecca Thompson From 1980 to 1985, the Australian Mesothelioma Surveillance Program, and since 1986, the Australian Mesothelioma Register, have been collecting data on all cases of malignant mesothelioma that could be ascertained in Australia. Incidence rates were calculated on 854 Program and 696 Register cases (total 1271) diagnosed in Australia between January 1, 1982 and December 31, Australia has one of the highest national rates of mesothelioma in the world (15.8 cases per million of population aged 20 years and older), and the rate is rising. The rate is far higher in males (28.3) than females (3.3). The Western Australian rate (28.9) is the highest among the states, as may be expected because of the crocidolite mine at Wittenoom; however, the largest numbers of cases occur in the more populous and industrial New South Wales. The high incidence rate, its expected continuing increase, and absence of a history of exposure to asbestos in approximately 28% of cases, demand consideration of potential environmental factors other than asbestos in the causation of this tumor, as well as continued surveillance. Key words: mesothelioma, incidence, Australia, asbestos exposure INTRODUCTION Between January 1, 1980 and December 31, 1985, the Australian Mesothelioma Surveillance Program (the Program) collected data on all known cases of malignant mesothelioma in Australia [Ferguson and Ng, 1980; Ferguson et ai., 1987]. From January 1, 1986, the Australian Mesothelioma Register (the Register) sought continued notification of cases, without the intensive data collection on each case mounted by the Program, in order to monitor the incidence, occupational associations, and geographic distribution of the disease. A parallel monitoring of incidence arising from exposure to crocidolite mining and milling at Wittenoom has been maintained by the Western Australian Mesothelioma Register [Armstrong et ai., 1984]. The need for monitoring arose because National Institute of Occupational Health and Safety, Sydney, Australia (J.L., C.F.C., A.G., D.A.F.). Department of Public Health, University of Sydney, Sydney, Australia (G.B.). New South Wales (NSW) Cancer Council, Sydney, Australia (R.T.). Address reprint requests to Dr. James Leigh, Head, Epidemiology Unit, National Institute of Occupational Health and Safety, GPO Box 58, Sydney, NSW 2001 Australia. Accepted for publication April 9, Wiley-Liss, Inc.

2 644 Leigh et al. between 1943 and 1966, Australia was a major producer of crocidolite, the type of asbestos fiber most strongly associated with onset of the tumor [Wagner et al., 1960; Wagner, 1986] and, during the 1950s, was one of the highest consumers of asbestos (mainly chrysotile) per head of population, especially in building products [Tariff Board Report on Asbestos Fibre Tariff Revision, 1955]. The asbestos cement industry used most of the imported chrysotile and amosite and a percentage of crocidolite mined at Wittenoom. Asbestos products still exist widely in the environment and remain a potential hazard. This paper is confined to one of the main aims of the Program and Register, that of tracing trends in occurrence in a country which appears to have a malignant mesothelioma incidence rate higher than that of any other country for which reasonably comparable data can be found [Ferguson et al., 1987]. METHOD The Program and later the Register actively sought notification of cases from a network of respiratory physicians, pathologists, general surgeons, medical superintendents, medical records administrators, state and territory divisions of occupational health and cancer registries, and state and commonwealth compensatory bodies. They also accepted notifications from any other source. Notifications from other than diagnosing physicians were confirmed with the treating physician. The Program Secretariat, after gaining the appropriate permissions, obtained on each case, either from the patient or next-of-kin, full occupational and environmental histories, which were analyzed by occupational hygienists. It also requested from the diagnosing pathologist slides and/or specimens on each case for circulation to the Pathology Panel appointed by the Royal College of Pathologists of Australia for confirmation of diagnosis. Wherever possible, the Secretariat obtained at postmortem lung tissue free of tumor for analysis by the Lung Fibre Counting Panel [Rogers, 1984]. The coded results from history taking, pathology diagnosis and lung fiber estimation were all forwarded to the Epidemiology Panel for computer entry and analysis. The Register used the same notification network as for the Program, without however seeking a detailed history, material for diagnosis, or lung fiber analysis and counting. Incidence rates were calculated on cases notified to the Program and Register by July 31,1990 diagnosed between 1982 and 1988 inclusive. Cases diagnosed prior to 1982 are likely to have been underreported and so were not included. Notification of some cases diagnosed in 1989 may not yet have occurred. Incidence was calculated nationally and by State and Territory using Australian Bureau of Statistics (ABS) estimated mid-year population figures for each year, for males and females aged 20 years and over [Australian Bureau of Statistics, 1987]. Cases notified to the Program and accepted by the Pathology Panel as "definite," "probable," or "possible" malignant mesothelioma were included in the calculation of incidence. A correction factor was applied to Register cases. This factor was based on the percentage of cases expected to be confirmed as mesothelioma according to the findings of the Pathology Panel on Program cases; this assumes that a similar fraction of cases would have been found not to be mesothelioma if there had been pathological review. Incidence rates were standardized to the World Standard Population aged 20 years and over using the direct method [Muir et al., 1987]. Confidence intervals of the standardized rates were

3 Mesothelioma in Australia 645 calculated based on a normal approximation assuming that the number of cases in each age group was a Poisson variable [Armitage and Berry, 1987]. For a group with less than 10 cases, the factors given by Bailar and Ederer [1964], based on the exact Poisson distribution, were used. The Secretariat searched all available published sources and corresponded with overseas mesothelioma registers and panels to obtain data on incidence in other countries. In the case of personal correspondence, for the most part, incidence rates had to be calculated from information supplied on the number of cases which had occurred in the country and from the Demographic Year Book census figures or estimates of country populations [United Nations, 1986]. Australian rates were then compared with the overseas rates. RESULTS The Program received notification of 854 cases with a presumptive diagnosis of mesothelioma. Ferguson et al. [1987] reported 871 cases as being notified to the Program. Subsequently, cases found not to be mesothelioma (prior to review by the RCPA Panel) have been subtracted from the number. To July 31,1990, the Register was notified of a further 696 cases which were presumptively diagnosed between 1982 and Of the 854 Program cases, 777 have to date been reviewed by the Pathology Panel. Of these 777 cases, 746 (96%) were confirmed as malignant mesothelioma; 565 were classed as "definite" (73%),131 as "probable" (17%) and 50 as "possible" (6%). Thirty-one cases were assessed as definitely not mesothelioma. In calculations of incidence rates for the period , all the Program cases (565 cases) diagnosed between 1982 and 1985, except those rejected by the Pathology Panel, were included. The 696 Register cases were included but a correction factor of 0.96 (746/777) was applied to allow for the assumed proportion not mesothelioma. The anatomical site of the mesothelioma was available for 824 of the cases. Among 723 men, 676 (93%) had a pleural mesothelioma, 38 (5%) a peritoneal mesothelioma, and 9 had tumors in other sites. Among 101 women, 84 (83%) had a pleural mesothelioma, and 17 (17%) had a peritoneal mesothelioma. The Australian crude incidence rate per million of population aged 20 years and over increased from 12.8 in 1982 to 19.6 in 1988 (Fig. 1). The fall in incidence in 1987 can be attributed to a fall in notification rate brought about by uncertainties in the notification network following the conclusion of the Program at the end of 1985 and the establishment of the Register in The male crude rate ranged from 22.7 to 35.9 during that period, and was about seven times the female crude rate ( ). The rates in 1988 are expected to increase marginally because of delay in notification of some cases. 1 Western Australia had the highest overall incidence rates (total, male and female) of any state or territory of Australia, all the rates being half as much again as those of South Australia, which had the second highest rate (Table I; Fig. 2). However, most cases came from New South Wales and Victoria because of the prepon- IThe crude annual incidence rate per million of population 2: 20 years for 1988 is 19.6; for 1989, 23.8; for 1990, 28.8; for 1991 (to 31st May), 35.0 (approximately).

4 646 Leigh et al. 40 u e C Males Persons Females I d r ate nce i r / /' I ~ *- 201 I~~~.~ o Year of diagnosis Fig. 1. Australian crude incidence rates of malignant mesothelioma per million of population aged ~20 years, by sex, inclusive. derance of the Australian population and industry on the eastern seaboard. More than 60% of Australia's population is in New South Wales and Victoria (Fig. 3). In all 854 Program cases, data are available for the state or territory of all known exposure to asbestos. In all Program cases and in the 696 Register cases to July 31, 1988, data are also available for cases in which exposure occurred at the crocidolite mining town of Witte noom in Western Australia; 64 (7.5%) ofthe 854 Program cases and 27 (5.5%) of the 492 Register cases, overall 91 (6.8%) of 1,346 cases, had a direct occupational or environmental exposure at Wittenoom. Among 776 Program cases coded for asbestos exposure, Western Australia had the highest proportion of notified cases with exposure to asbestos in the same state and the lowest proportion of unexposed cases. Almost 70% of cases with first exposure in Western Australia received that exposure at Wittenoom (Table II). The relatively high incidence rate in South Australia, not a higwy industrialized state, was attributable mainly to that state having the highest proportion of cases first exposed overseas and the third highest proportion first exposed in another state or territory. About half had their exposure in the state or territory of notification, and about one in ten of exposed cases had an exposure overseas before migrating to Australia. Generally, about 28% of Program cases gave no history of exposure. For the combined sexes, the highest average annual crude incidence rate for the 7 years combined (61.3) occurred in the group aged years (Table III). Among males and females overall, the rate increased with age up to 79 years and then declined. Generally, incidence rates increased each year within age groups. Comparison of the Australian incidence rate has been made with some countries

5 ustralian Standardized " " a a a rateconfidence " a a limits Males 647 rate Mesothelioma in Australia Mesothelioma Territory Register* 95% *Australian mesothelioma incidence rates per million of population aged 2:20 years inclusive. afewer than 10 cases. that have in the past been major consumers of asbestos (Table IV). The Australian national rate (15.8) is the highest of those countries listed. However, the white South African male incidence rate (32.9) is higher than the Australian male rate (28.0) and the female colored South African rate (13.9) and the female white South African rate (8.9) [Zwi et ai., 1989] are higher than the Australian female rate (3.6). The national incidence rate for South Africa is not given. The rates for Northern Ireland (14.7) [Langlands, 1987], Norwegian males (13.0) [Mowe et ai., 1990], Dutch males (20.9) [Meijers et ai., 1990], and the expected national rate for South Africa are the only national rates to approach that for Australia in overall incidence. In some regions, incidence rates approach those of some states of Australia, for example, Rotterdam and Flushing [Planteydt, 1979] and some regional death rates in Great Britain [Jones et ai., 1988]. However, comparability cannot be strict because of differences in research parameters and methods, varying population and age bases, exclusion or underreporting of cases of mesothelioma of the peritoneum, pericardium, and tunica

6 648 Leigh et al. S ta 60 n 50 d a r d i z e d 40 ~ Males i n c i d e n c e r a t e o WA SA NSW QLD VIC TAS ACT NT State or territory of Australia Persons _ Females Fig. 2. Australian standardized incidence rates of malignant mesothelioma per million of population 2':20 years, by state and sex, inclusive. vaginalis, limitation to occupational asbestos exposure (compensation claims), differences in time period and in standards of histological confirmation, and use of standardized and nonstandardized rates. DISCUSSION Monitoring of malignant mesothelioma by the Program and Register has confirmed that Australia has an overall incidence rate apparently higher than that of other countries that have been major producers and/or consumers of asbestos and that the rate is rising. This rise has been continuous since 1947 [Musk et ai., 1989]. Certainly the rate is outstanding and in Western Australia far exceeds the experience of any other country or region, with the exception of Karain, Turkey, where exposure was to erionite [Baris et ai., 1981]. However, the circumstances there are hardly comparable. It would be expected that the South African national incidence rate would be of a magnitude similar to that of Australia. Although the male and female national death rates for Great Britain are lower than the Australian incidence rates, some of the former's regional death rates [Jones et ai., 1988] approach those of some of the states of Australia. Australia has a lower percentage of peritoneal cases reported than in Great Britain [Jones et ai., 1988] or South Africa [Zwi et ai., 1989]. The percentage of peritoneal cases is greater in females than in males which is consistent with trends from other studies [Zwi et ai., 1989; Jones et ai., 1988]. The extent to which the Australian pre-eminence in rates internationally and to which the rising rate over the period in Australia represent a genuine excess and secular increase in

7 Mesothelioma in Australia 649 /\ \ \ Wlttenoom Mine Northern Territory (0.9%) I R 5.8 Queensland (16.2%) IR 14.3 (8.9%) IR 28.9 South Australia (8.7%) IR 19.5 Aust Capital Territory (1.6%) IR 10.1 \; V (2.8%) TasmaniaIR 4.6 Fig. 3. State and territory proportion (%) of national population of Australia and standardized lllcloence rates (IR) of malignant mesothelioma per million of population aged 2:20 years, inclusive. incidence, or rather a more complete reporting, owing to enhanced awareness of the tumor and of the Program and Register, is not clear. The continuity of the increase since 1947, however, supports a real effect. The incidence rates across states and territories of Australia are not uniform. The high rate in Western Australia is due in large part to the number of cases exposed occupationally and/or environmentally at the Wittenoom crocidolite mine, most of whom have remained resident in that state; in 53% of asbestos exposed cases in that state, exposure occurred at Wittenoom. The high rate in South Australia was increased mainly by migration of cases from other states (14.3%) and from overseas (15.6%). The degree of migration has not been as great for other states or territories except Queensland and Tasmania. Queensland is a state that tends to receive postretirement migration from southern states. Previous analysis indicates that the relatively high New South Wales rate is probably due to: (1) the asbestos product manufacture that occurred there; (2) use of the product from the 1930s to 1960s; and (3) the fact that it is the most heavily industrialized state, with widespread use of asbestos in lagging, thermal insulation, soundproofing, and packing [Ferguson et al., 1987]. The overall increase in incidence rate with age up to 79 years and then decline may have been a cohort effect in that very aged people were past the time of risk of exposure when major use of asbestos escalated during the late 1940s and 1950s. Overall, the female incidence rate of 3.3 per million aged ~20 years was higher

8 650 Leigh NSWc QLD TAS SAb VIC No. of Program cases (n=77) (n=94) (n=386) = Ill) et 13) al. (n=97) Wittenoom Asbestos territory, excluding Exposure* exposures TABLE II. Notifications to Australian Mesothelioma Surveillance State Program of diagnosis Coded for *Proportion (%) of cases (n = 778) by place of first exposure to asbestos and state or territory of residence at time of diagnosis. adocumented first exposure to asbestos, irrespective of type, severity, or regularity. bcases from Northern Territory are included with South Australia. ccases from Australian Capital Territory are included with New South Wales. TABLE III. Notifications to Australian Mesothelioma Surveillance Program and Australian Mesothelioma Register* :::: Ten-year age groups *Australian age-specific crude incidence rates by age at diagnosis and sex, than would be expected on the basis of almost exclusively male occupational exposure to asbestos during the 1940s to 1960s [McDonald and McDonald, 1977]; 24% of women had some form of exposure to asbestos compared to 75% in males. This relatively high incidence with relatively low exposures may be due to women with no elicited exposure having received exposures environmentally, for example by living adjacent to primary asbestos production or cohabiting with a primary asbestos production worker. Owing to differences in time and age periods and in criteria of case collection, comparison of incidence rates from different countries is of dubious validity. For example, in some countries, such as Germany, mainly cases with asbestos exposure are notified, as in compensation cases [Otto, 1986]; and in some countries peritoneal mesothelioma has been relatively underreported [Bignon et al., 1979; Bignon, personal communication, 1986] although such is also thought to be the case in Australia. Generally, high rates, both overall and in males and females, tend to occur in

9 Mesothelioma in Australia 651 countries, provinces, states or cities known for their shipbuilding, general manufacturing and asbestos cement manufacturing. In the countries or regions with high incidence, such as Australia, British Columbia [Churg, 1985], England, Scotland, and Wales [Jones et al., 1988], Netherlands [Planteydt, 1979; Zambon et al., 1983; Meijers et al., 1990], Norway [Mowe and Gylseth, 1986; Mowe et al., 1990], Switzerland [Ruttner, 1987], and Connecticut [Lewisohn et al., 1980], but excluding Denmark [Andersson and Olsen, 1985], the male rate was 5-9 times the female rate. Where both earlier and more recent data were available for a region, the later rates were always higher. The rates for some countries therefore, such as Canada, Finland, and the United States, could be expected to have risen since the periods listed. Trends in the United States show an increase from 1973 to 1980, especially among older persons [Spirtas et al., 1986]. Information on the incidence rates of South Africa (a major crocidolite producer) is not given in Table IV, as the number of mesothelioma cases for the whole population was not available. The question arises, then, whether Australia's incidence rate is really one of the highest in the world and, if so, why? Some factors possibly contributing to the high Australian rate include the following: efficient reporting due to awareness of the disease and promotion of the Program and Register; widespread use of crocidolite in asbestos manufacturing, shipbuilding, railway, and metal fabrication and construction industries [Ferguson et al., 1987]; poor industrial hygiene record [Layman, 1983]; the post-world War II building boom, which saw more than 50% of housing construction in Australia being of asbestos cement sheeting [Layman, 1983], leading to Australia's position as the fourth largest consumer of asbestos cement products and the highest per capita user of asbestos in the world during the 1950s [Tariff Board of Asbestos Fibre Tariff Revision, 1955]; and the crocidolite mine at Wittenoom, which has been directly associated with 91 of the 1,346 cases collected by the Program and Register. Clearly, fiber type from this region is a major factor as it has been shown to have physical properties different from and likely to be more hazardous than those of crocidolite mined elsewhere [Timbrell et al., 1988]. Lung fiber content estimations show that about 60% of cases are also exposed to chrysotile and amosite [Rogers et al., 1991]. In about 28% of cases in the Program, there was no historical record of asbestos exposure despite intensive search. However, only about 7% of cases have lung fiber counts below the transmission electron microscope detection limit [Leigh et al., 1991]. This difference is presumably attributable to environmental exposure. Since there is also a dose-response relationship for asbestos-related mesothelioma [Rogers et al., 1991], the low-level lung fiber contents are not necessarily evidence of causality. Consideration therefore, needs to be given to other possible contributory factors to the high Australian incidence rate. With the large amounts of asbestos still in the environment, regular monitoring should occur to ensure safe work and domestic environments. A detailed analysis of the occupational and industrial asbestos exposure of Program cases is in preparation. ACKNOWLEDGMENTS We wish to thank the following people for their contribution to the work of the Program and Register. Dr. Theo Constance, Dr. Phillip W. Allen, Professor A. Harold Attwood, Dr. Douglas W. Henderson, Dr. Keith Shilkin, and Dr. Richard H. Steele of the Royal College of Pathologi~ls of Australasia Pathology Panel; Dr.

10 anada Quebec Republic) 245 yr - - I TABLE Greenberg IV. Churg Bignon Asbestos McDonald Donna Nurminen ~70h ~79h Otto ~45 Bignon ~90 ~54 ~67 EXp",d (%) 0.03 Females" 0,9 0,3g International c 4, ,Og ,3 0, (%) Males" incidence" et 11986] [ al [1986] and 3.4g J and , ~ [19791 Andersson Lloyd Reference McDonald 93 Incidence , >20 Davies Years 1975 and yr " Jones Zambon McDonald 11977J of Olsen Cont" Mesothelioma: et al. et and al J [ , McDonald JCountry, ) McDonald State, Province, and McDonald City and 4.4 Scotland Hist

11 Puget Sound Netherlandsi P1anteydt ].4 2.5f 3.6f I] [1979] Meijers 14.7g g 1980-]984 et al. [1990] Meijers 20.9f 1O.8f j Langlands Wright Hinds I-linds Ruttner j Mowe Baris loom ~ k 70h 82h g II g [1978] Iet and ] et Ial. Colored 11987] Gylseth White [1984] [ ;() 85% Lewisohn [ g ' females ] et Hinds McDonald al. Zwi et [19781 [1978] 11978] 100 al. et ~40 al. and [1989] ~20 [1990] McDonald mall I1Person-years. kmales of ipleural 'Per gcalculated Demographic hoccupational imajority [United estimates thousand. exposed 93 with mesothelioma Nations, ofp1anteydt from cases. occupational to Year exposure Planteydt country erionite figures 1986]. Book [] only. 987] populations only. fibers. I] provided census exposure. 979] figures using Kanton Karain Walcheren of Zurich 1sland)

12 654 Leigh et ai. Thomas Ng, World Health Organisation, Geneva, and Mr. Gersh Major, Consulting Occupational Hygienist, both of whom were instrumental in the development of the Program; Mrs. Sally Andreas, the original Registrar of the Program; Dr. Joyce Ford of the NSW Cancer Registry; Dr. Julian Lee, The Thoracic Society of Australia's representative; all the colleagues throughout Australia who participated in the Australian Mesothelioma Surveillance Program, particularly the state occupational health division medical officers, the state department of health community nurses, and private clinicians and pathologists. The Program has received support from the National Health and Medical Research Council, the NSW Workers' Compensation (Dust Diseases) Board and various other donors, and has been fully funded by the National Occupational Health and Safety Commission since REFERENCES Andersson M, Olsen JH (1985): Trend and distribution of mesotheliomas in Denmark. Br J Cancer 51: Armitage P, Berry G (1987): "Statistical Methods in Medical Research," 2nd Ed. Oxford: Blackwell, pp Armstrong BK, Musk AW, Baker JE, Hunt JM, Newall CC, Henzel! HR, Blunsdon BS, Clarke-Hundey MD (1984): Epidemiology of malignant mesothelioma in Western Australia. Med J Aust 141: Australian Bureau of Statistics (1987): Estimated resident population by sex and age: States and territories of Australia. June 1981 to June Canberra (Catalogue No ). Bailar JC, Ederer F (1964): Significant factors for the ratio of a Poisson variable to its expectation. Biometrics 20: Baris YI, Simonato L, Saracci R, Skidmore JW (1981): Malignant mesothelioma and radiological chest abnormalities in two villages in Central Turkey. Lancet 1: Bignon J (1986): French Mesothelioma Register, Centre Hospitalier Intercommunal, 40. Ave de Verdun, Creteil Cedex, France. Personal communication. Bignon J, Sebastien P, Di Menza L, Payan H (1979): French Mesothelioma Register. Ann NY Acad Sci 330: Churg A (1985): Malignant mesothelioma in British Columbia. Cancer 55: Donna A (1987): Italian Representative of CEC Mesothelioma Panel. Personal communication. Ferguson D, Ng TG (1980): Australian Mesothelioma Register. Med J Aust 1: Ferguson DA, Berry G, Jelihovsky R, Andreas SB, Rogers AJ, Chung Fung S, Grimwood A, Thompson R (1987): The Australian Mesothelioma Surveillance Program Med J Aust 147: Greenberg M, Lloyd Davies TA (1974): Mesothelioma Register Br J Ind Med 31: Hinds WM (1978): Mesothelioma in the United States. J Occup Med 20: Jones RD, Smith DM, Thomas PG (1988): Mesothelioma in Great Britain. Scand J Work Environ Health 14:145-i52. Langlands JHM (1987): Register of Mesothelioma-Northern Ireland. Respiratory Investigation Centre, Belfast City Hospital, 93 Lisburn Road, Belfast BT 9 7 AB. Personal communication. Layman L (1983): Work and worker's responses at Wittenoom, Community Health Studies 7:1-18. Leigh J, Rogers AJ, Ferguson DA, Mulder HB, Ackad M, Thompson R (1991): Lung asbestos fiber content and mesothelioma cell type, site and survival. Cancer 68: Lewisohn HC, Meigs JW, Tete MJ, Flannery JT (1980): The influence of occupational and environmental asbestos on the incidence of malignant mesothelioma in Connecticut. In Wagner JC (ed): "Biological Effects of Mineral Fibres." Lyon: IARC Sci Pub 39 pp McDonald JC, McDonald AD (1977): Epidemiology of mesothelioma from estimated incidence. Prevent Med 6: Meijers JMM, Planteydt HT, Swaen GMH (1990): Asbestos exposure and pleural mesotheliomas in the

13 Mesothelioma in Australia 655 Netherlands-Trends and geographical patterns rd Int Cong Occup Health 610 (abst). Mowe G, Andersen A, Osvoll P (1990): Malignant mesothelioma in Norway registered by the Cancer Registry and notified to the Labour Inspection between rd Int Congr Occ Health: 611 (abst). Mowe G, Gylseth B (1986): Occupational exposure and regional variation of malignant mesothelioma in Norway, Am J Ind Med 9: Muir C, Waterhouse J, Mack T, Powell J, Whelan S (1987): "Cancer Incidence in Five Continents. Vol. 5." Lyon: IARe. Musk AW, Dolin PJ, Armstrong BK, Ford JM, de-klerk NH, Hobbs MS (1989): The incidence of malignant mesothelioma in Australia Med J Aust 150: Nurminen M (1975): The epidemiologic relationship between pleural mesothelioma and asbestos exposure. Scand J Work Environ Health 1: Otto H (1986): Pathologisches Institut der Stodt Kliniken, Beurhausstr. 40, 6400 Dortmund I, Federal Republic of Germany. Personal communication. Planteydt HT (1979): Netherlands Mesothelioma Register. Ann NY Acad Sci 330: Planteydt HT (1987): Netherlands Mesothelioma Register. Streeklaboratorium, Zeeland, Molenwater 47, 4331SC Middelburg, Netherlands. Personal communication. Rogers AJ (1984): Determination of mineral fibre in human lung tissue by light microscopy and transmission electron microscopy. Ann Occup Hyg 28:1-12. Rogers AJ, Leigh J, Berry G, Ferguson DA, Mulder HB, Ackad M, (1991): Relationship between lung asbestos fiber type and concentration and relative risk of mesothelioma. A case-control study. Cancer 67: Ruttner JR (1987): Zurich Pneumoconiosis Research Group. Institute of Pathology, University Hospital, CH-8091, Zurich. Personal communication. Spirtas R, Beebe GW, Connelly RR, Wright WE, Peters JM, Sherwin RP, Henderson BE, Stark A, Kovasznay BM, Davies JNP, Vianna NJ, Keehn RJ, Ortega LG, Hochholzer L, Wagner JC (1986): Recent trends in mesothelioma incidence in the United States. Am J Ind Med 9: , Tariff Board Report on Asbestos Fibre Tariff Revision (1955): Appendix B Summary of Evidence. Canberra: Government Printing Office, September 1955, pp 16. Timbrell V, Ashcroft T, Goldstein B, Heyworth F, Meurman LO, Randall REG, Reynolds JA, Shilkin KB, Whitaker D (1988): Relationships between retained amphibole fibres and fibrosis in human lung tissue specimens. Ann Occup Hyg (suppl 1), 32: United Nations Department ofinternational Economic and Social Affairs, Statistical Office. (1986): 1986 Demographic Year Book. United Nations, New York, pp Wagner JC (1986): Mesothelioma and mineral fibers. Cancer 57: Wagner JC, Sleggs CA, Marchand P (1960): Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province. Br J Ind Med 17: Wright WE, Sherwin RP, Dickson EA, Bernstein L, Fronn J, Henderson BE (1984): Malignant mesothelioma: Incidence, asbestos exposure and reclassification of histopathology. Br J Ind Med 41: Zambon P, Simonato L, Mastrangelo G, Saia B, Chieco-Bianchi L (1983): Age characteristics of mesothelioma incidence in the general population of the Province of Padova Tumori 69: Zwi AB, Reid G, Landau SP, Kielkowski D, Sitas F, Becklake MR (1989): Mesothelioma in South Africa : incidence and case characteristics. Int J EpidemioI18:

Malignant Mesothelioma in Australia, 1945 2000

Malignant Mesothelioma in Australia, 1945 2000 Ann. occup. Hyg., Vol. 46, Supplement 1, pp. 160 165, 2002 2002 British Occupational Hygiene Society Published by Oxford University Press DOI: 10.1093/annhyg/mef669 Malignant Mesothelioma in Australia,

More information

Mesothelioma in Australia: Incidence (1982 to 2013) and Mortality (1997 to 2012)

Mesothelioma in Australia: Incidence (1982 to 2013) and Mortality (1997 to 2012) Mesothelioma in Australia: Incidence (1982 to 213) and Mortality (1997 to 212) 215 Disclaimer The information provided in this document can only assist you in the most general way. This document does not

More information

MESOTHELIOMA IN AUSTRALIA INCIDENCE 1982 TO 2009 MORTALITY 1997 TO 2011

MESOTHELIOMA IN AUSTRALIA INCIDENCE 1982 TO 2009 MORTALITY 1997 TO 2011 MESOTHELIOMA IN AUSTRALIA INCIDENCE 1982 TO 29 MORTALITY 1997 TO 211 OCTOBER 213 Safe Work Australia Mesothelioma in Australia Incidence 1982 to 29 Mortality 1997 to 211 OCTOBER 213 Acknowledgement Disclaimer

More information

MESOTHELIOMA IN AUSTRALIA INCIDENCE 1982 TO 2008 MORTALITY 1997 TO 2007

MESOTHELIOMA IN AUSTRALIA INCIDENCE 1982 TO 2008 MORTALITY 1997 TO 2007 MESOTHELIOMA IN AUSTRALIA INCIDENCE 1982 TO 28 MORTALITY 1997 TO 27 August 212 Safe Work Australia Mesothelioma in Australia Incidence 1982 to 28 Deaths 1997 to 27 August 212 Acknowledgement Data on the

More information

Lessons learned from the Western Australian experience with mesothelioma

Lessons learned from the Western Australian experience with mesothelioma Lessons learned from the Western Australian experience with mesothelioma Alison Reid, Western Australian Institute for Medical Research In partnership with Nick de Klerk, Nola Olsen, Jan Sleith, Geoffrey

More information

Table 2.4. Summary of design and findings from mesothelioma case-control studies

Table 2.4. Summary of design and findings from mesothelioma case-control studies categories Agudo et al. (2000) Barcelona and Cadiz, Spain 32 cases (77% males) of histologically con rmed malignant pleural mesothelioma identified from hospital in the region between //993 and 2/3/996.

More information

Changing Trends in Mesothelioma Incidence. Hans Weill, M.D. Professor of Medicine Emeritus Tulane University Medical Center

Changing Trends in Mesothelioma Incidence. Hans Weill, M.D. Professor of Medicine Emeritus Tulane University Medical Center Changing Trends in Mesothelioma Incidence Hans Weill, M.D. Professor of Medicine Emeritus Tulane University Medical Center International Conference on Chrysotile Montreal, May 23, 2006 Global Mesothelioma

More information

Scientific Update on Safe Use of Asbestos. Robert P. Nolan, PhD International Environmental Research Foundation New York, New York www.ierfinc.

Scientific Update on Safe Use of Asbestos. Robert P. Nolan, PhD International Environmental Research Foundation New York, New York www.ierfinc. Scientific Update on Safe Use of Asbestos Robert P. Nolan, PhD International Environmental Research Foundation New York, New York www.ierfinc.org When We Talk about Asbestos What Do We Mean? Anthophyllite

More information

Trends and geographical patterns of pleural mesotheliomas in the Netherlands 1970-87

Trends and geographical patterns of pleural mesotheliomas in the Netherlands 1970-87 British Journal of ndustrial Medicine 1990;47:775-781 Trends and geographical patterns of pleural mesotheliomas in the Netherlands 1970-87 775 J M M Meijers, H T Planteydt, J J M Slangen, G M H Swaen,

More information

MESOTHELIOMAS - ASBESTOS EXPOSURE AND LUNG BURDEN

MESOTHELIOMAS - ASBESTOS EXPOSURE AND LUNG BURDEN MESOTHELIOMAS - ASBESTOS EXPOSURE AND LUNG BURDEN G. Berry Department of Public Health, University of Sydney, Australia A.J. Rogers National Occupational Health and Safety Commission, University of Sydney,

More information

Epidemiology of Malignant Mesothelioma An Outline

Epidemiology of Malignant Mesothelioma An Outline Commentary Ann. Occup. Hyg., Vol. 54, No. 8, pp. 851 857, 2010 Ó The Author 2010. Published by Oxford University Press on behalf of the British Occupational Hygiene Society doi:10.1093/annhyg/meq076 Epidemiology

More information

The expected burden of mesothelioma mortality in Great Britain from 2002 to 2050

The expected burden of mesothelioma mortality in Great Britain from 2002 to 2050 British Journal of Cancer (25) 92, 587 593 & 25 Cancer Research UK All rights reserved 7 92/5 $3. www.bjcancer.com The expected burden of mesothelioma mortality in Great Britain from 22 to 25 JT Hodgson*,1,

More information

Actuarial projections for mesothelioma: an epidemiological perspective Mark Clements, Geoffrey Berry and Jill Shi

Actuarial projections for mesothelioma: an epidemiological perspective Mark Clements, Geoffrey Berry and Jill Shi Actuarial projections for mesothelioma: an epidemiological perspective Mark Clements, Geoffrey Berry and Jill Shi 27 slides to go Who are we? I am an epidemiologist/biostatistician from the Australian

More information

Mesothelioma mortality in Great Britain 1968-2009. Summary 2. Overall scale of disease including trends 3. Region 6. Occupation 7

Mesothelioma mortality in Great Britain 1968-2009. Summary 2. Overall scale of disease including trends 3. Region 6. Occupation 7 Health and Safety Executive Mesothelioma Mesothelioma mortality in Great Britain 1968-2009 Contents Summary 2 Overall scale of disease including trends 3 Region 6 Occupation 7 Estimation of the future

More information

Asbestos Health Risks. Dr Andrew Pengilley Acting Chief Health Officer

Asbestos Health Risks. Dr Andrew Pengilley Acting Chief Health Officer Asbestos Health Risks Dr Andrew Pengilley Acting Chief Health Officer Asbestos Asbestos is a name given to several different fibrous minerals Three main commercial types are Chrysotile (white asbestos)

More information

THE AUSTRALIAN MESOTHELIOMA REGISTRY (AMR)

THE AUSTRALIAN MESOTHELIOMA REGISTRY (AMR) THE AUSTRALIAN MESOTHELIOMA REGISTRY (AMR) Professor Nico van Zandwijk Director Asbestos Diseases Research Institute US US UK UK COUNTRY NZ CAN COUNTRY NZ CAN AUS AUS Mesothelioma International context

More information

The Australian Mesothelioma Surveillance Program 1979-1985

The Australian Mesothelioma Surveillance Program 1979-1985 166 August 17, 1987 Vol. 147 THE MEDICAL JOURNAL OF AUSTRALIA The Australian Mesothelioma Surveillance Program 1979-1985 David A. Ferguson, Geoffrey Berry, Tatiana )elihovsky, Sally B. Andreas, Alan ).

More information

PATTERNS OF MORTALITY IN ASBESTOS FACTORY WORKERS IN LONDON*

PATTERNS OF MORTALITY IN ASBESTOS FACTORY WORKERS IN LONDON* PATTERNS OF MORTALITY IN ASBESTOS FACTORY WORKERS IN LONDON* M. L. Newhouse TUC Centenary Institute of Occupational Health London School of Hygiene and Tropical Medicine London WCIE 7HT. England G. Berry

More information

Call for an International Ban on Asbestos

Call for an International Ban on Asbestos Call for an International Ban on Asbestos To eliminate the burden of disease and death that is caused worldwide by exposure to asbestos, The Collegium Ramazzini calls for an immediate ban on all mining

More information

Influence of Fiber Type, Size, and Number in Human Disease: Conclusions from Fiber Burden Analysis

Influence of Fiber Type, Size, and Number in Human Disease: Conclusions from Fiber Burden Analysis Influence of Fiber Type, Size, and Number in Human Disease: Conclusions from Fiber Burden Analysis Andrew Churg, MD Department of Pathology University of British Columbia Vancouver, BC, Canada Techniques,

More information

NHS Barking and Dagenham Briefing on disease linked to Asbestos in Barking & Dagenham

NHS Barking and Dagenham Briefing on disease linked to Asbestos in Barking & Dagenham APPENDIX 1 NHS Barking and Dagenham Briefing on disease linked to Asbestos in Barking & Dagenham 1. Background 1.1. Asbestos Asbestos is a general name given to several naturally occurring fibrous minerals

More information

Emerging evidence that the ban on asbestos use is reducing the occurrence of pleural mesothelioma in Sweden

Emerging evidence that the ban on asbestos use is reducing the occurrence of pleural mesothelioma in Sweden 596500SJP0010.1177/1403494815596500B. Järvholm and A. BurdorfAsbestos ban reduces mesothelioma incidence research-article2015 Scandinavian Journal of Public Health, 1 7 Original Article Emerging evidence

More information

Malignant Mesothelioma Among Employees of a Connecticut Factory that Manufactured Friction Materials Using Chrysotile Asbestos

Malignant Mesothelioma Among Employees of a Connecticut Factory that Manufactured Friction Materials Using Chrysotile Asbestos Ann. Occup. Hyg., Vol. 54, No. 6, pp. 692 696, 2010 Ó The Author 2010. Published by Oxford University Press on behalf of the British Occupational Hygiene Society doi:10.1093/annhyg/meq046 Malignant Mesothelioma

More information

Asbestos: health effects and risk. Peter Franklin Senior Scientific Officer, EHD Senior Research Fellow, UWA

Asbestos: health effects and risk. Peter Franklin Senior Scientific Officer, EHD Senior Research Fellow, UWA Asbestos: health effects and risk Peter Franklin Senior Scientific Officer, EHD Senior Research Fellow, UWA What is asbestos Naturally occurring mineral that has crystallised to form long thin fibres and

More information

Mesothelioma among brake mechanics: an expanded analysis of a casecontrol

Mesothelioma among brake mechanics: an expanded analysis of a casecontrol 1 Risk Anal. 2004 Jun;24(3):547-52. Related Articles, Links Mesothelioma among brake mechanics: an expanded analysis of a casecontrol study. Hessel PA, Teta MJ, Goodman M, Lau E. Exponent, Wood Dale, IL

More information

Update of the scientific evidence on asbestos and cancer. Kurt Straif, MD MPH PhD. The IARC Monographs

Update of the scientific evidence on asbestos and cancer. Kurt Straif, MD MPH PhD. The IARC Monographs Update of the scientific evidence on asbestos and cancer Kurt Straif, MD MPH PhD International Agency for Research on Cancer Lyon, France World Health Organisation Asturias, 17 March 2011 The IARC Monographs

More information

HANDLING LUNG CANCER CLAIMS

HANDLING LUNG CANCER CLAIMS HANDLING LUNG CANCER CLAIMS JENNIFER S. KILPATRICK SWANSON, MARTIN & BELL, LLP 330 North Wabash Avenue Suite 3300 Chicago, Illinois 60611-3604 (312) 321-3517 (312) 321-0990 jkilpatrick@smbtrials.com 1

More information

Preparing an estimate of the national pattern of exposure to asbestos in cases of malignant mesothelioma

Preparing an estimate of the national pattern of exposure to asbestos in cases of malignant mesothelioma Preparing an estimate of the national pattern of exposure to asbestos in cases of malignant mesothelioma JULY 2008 Copyright Notice Commonwealth of Australia 2008 ISBN 978 0 642 32792 5 This work is copyright.

More information

Relationship Between Lung Asbestos Fiber Type and Concentration and Relative Risk of Mesothelioma

Relationship Between Lung Asbestos Fiber Type and Concentration and Relative Risk of Mesothelioma Reprinted from CANCER, Vol. 67, No.7, April I, 1991. Copyright 1991, by the American Cancer Society, Inc. J. B. Lippincott Company. Printed in U.SA Relationship Between Lung Asbestos Fiber Type and Concentration

More information

Malignant mesothelioma: incidence, asbestos

Malignant mesothelioma: incidence, asbestos British Journal of Industrial Medicine 1984;41: 39-45 Malignant mesothelioma: incidence, asbestos exposure, and reclassification of histopathology W E WRIGHT,' R P SHERWIN,2 ELIZABETH A DICKSON,' L BERNSTEIN,'

More information

In the course of this work we observed:

In the course of this work we observed: $6%(67265(/$7('',6($6(6 7+(,1685$1&(&267 SUHSDUHGE\ 7LP$QGUHZVDQG*HRII$WNLQV,QWURGXFWLRQ The ideas for this paper evolved out of studies we were asked to undertake by a number of insurers involving estimation

More information

Asbestos-Related Cancer Research and Prevention

Asbestos-Related Cancer Research and Prevention Asbestos-Related Cancer Research and Prevention Professor Nico van Zandwijk Asbestos Diseases Research Institute University of Sydney International Conference on Asbestos Awareness and Management 18 November

More information

The Carcinogenicity of Chrysotile Asbestos A Review

The Carcinogenicity of Chrysotile Asbestos A Review Industrial Health 2001, 39, 57 64 Review Article The Carcinogenicity of Chrysotile Asbestos A Review William J. NICHOLSON Mount Sinai School of Medicine, NY, NY, USA Received December 23, 2000 and accepted

More information

Survey on the Mortality from Malignant Tumors of Female Asbestos Spinning Workers

Survey on the Mortality from Malignant Tumors of Female Asbestos Spinning Workers Table of Contents WS-E-12 Xing Zhang Survey on the Mortality from Malignant Tumors of Female Asbestos Spinning Workers Xing Zhang 1, Tong-da Sun 2, Nan-feng Shi 2, Li-qiu Zhu 1, Kenji Morinaga 3 1 Institute

More information

Compensation for Environmental and Domestic Exposure Cases

Compensation for Environmental and Domestic Exposure Cases Table of Contents PL-5-01 Bob Ruers Compensation for Environmental and Domestic Exposure Cases Bob Ruers Former Dutch Senator, founding member of Dutch Asbestos Committee and Solicitor, the Netherlands

More information

ASBESTOS FIBRES IN THE LUNGS OF CHRYSOTILE MINERS AND MILLERS A PRELIMINARY REPORT

ASBESTOS FIBRES IN THE LUNGS OF CHRYSOTILE MINERS AND MILLERS A PRELIMINARY REPORT Ann. occup. llyy.. Vol.. Mos. I 4. pp. 4-4. 98. Primed in Great Bnlain. Inhaled Panicles V 0003 4878/8,004-OSO3.00/O Pergamon Press Lid. (' 98 British Occupational Hygiene Society. ASBESTOS FIBRES IN THE

More information

Mesothelioma Incidence and Community Asbestos Exposure

Mesothelioma Incidence and Community Asbestos Exposure ENVIRONMENTAL RESEARCH 75, 34 40 (1997) ARTICLE NO. ER973770 Mesothelioma Incidence and Community Asbestos Exposure Michael Berry Consumer and Environmental Health Services, New Jersey Department of Health

More information

THE EPIDEMIOLOGY OF MESOTHELIOMA IN HISTORICAL CONTEXT

THE EPIDEMIOLOGY OF MESOTHELIOMA IN HISTORICAL CONTEXT occupational safety and health service THE EPIDEMIOLOGY OF MESOTHELIOMA IN HISTORICAL CONTEXT J.C. McDonald, A.D. McDonald OCCUPATIONAL SAFETY & HEALTH SERVICE DEPARTMENT OF LABOUR TE TARI MAHI 1 Emeritus

More information

BY THE NUMBERS: THE FUTURE OF MESOTHELIOMA IN AMERICA

BY THE NUMBERS: THE FUTURE OF MESOTHELIOMA IN AMERICA BY THE NUMBERS: THE FUTURE OF MESOTHELIOMA IN AMERICA 1 CUTTING-EDGE ISSUES IN ASBESTOS LITIGATION CONFERENCE Scott Masterson Lewis, Brisbois, Bisgaard & Smith, LLP 1180 Peachtree Street, NE, Suite 2900

More information

Occupational Heath and Safety Section American Public Health Association

Occupational Heath and Safety Section American Public Health Association Occupational Heath and Safety Section American Public Health Association THE ELIMINATION OF ASBESTOS (Resolution No. 20096, Adopted 11/10/2009) As early as 1898, British government factory inspectors recognized

More information

Health effects of occupational exposure to asbestos dust

Health effects of occupational exposure to asbestos dust Health effects of occupational exposure to asbestos dust Authors: N.Szeszenia-Dąbrowska, U.Wilczyńska The major health effects of workers' exposure to asbestos dust include asbestosis, lung cancer and

More information

Current Usage and Health Significance of the Modern Use of Chrysotile Products: Review of Recently Published Evidence

Current Usage and Health Significance of the Modern Use of Chrysotile Products: Review of Recently Published Evidence Current Usage and Health Significance of the Modern Use of Chrysotile Products: Review of Recently Published Evidence John Hoskins Health & Safety Consultant, Haslemere, Surrey, UK ASBESTOS SERPENTINE

More information

Asbestos related cancers

Asbestos related cancers New cancer cases 1954-215 in Finland, Men Pukkala et al. 26 Asbestos related cancers Panu Oksa, MD, docent Course on asbestos-related diseases Tartu 4-5.12.26 Asbestos related cancer / FIOH / PO / 1.1.27

More information

Occupational respiratory diseases due to Asbestos. Dirk Dahmann, IGF, Bochum

Occupational respiratory diseases due to Asbestos. Dirk Dahmann, IGF, Bochum Occupational respiratory diseases due to Asbestos Dirk Dahmann, IGF, Bochum Contents Introduction Diseases Further Effects Preventive Strategies Conclusion Asbestos minerals Woitowitz, 2003 Imports (+

More information

Mesothelioma Trends as Predictors of the Asbestos- Related Lung Cancer Burden

Mesothelioma Trends as Predictors of the Asbestos- Related Lung Cancer Burden Mesothelioma Trends as Predictors of the Asbestos- Related Lung Cancer Burden Valerie McCormack UICC World Cancer Congress Montreal August 2012 Outline Background Estimating the lung cancer mortality burden

More information

Asbestos and the diseases it causes

Asbestos and the diseases it causes Asbestos and the diseases it causes October 2013 Liz Darlison Mesothelioma UK University Hospitals of Leicester Contents What is asbestos Why is it such an issue in the UK Disease Statistics Asbestos Related

More information

Future Trends of Mesothelioma Mortality in Japan Based on a Risk Function

Future Trends of Mesothelioma Mortality in Japan Based on a Risk Function Industrial Health 2012, 50, 197 204 Original Article Future Trends of Mesothelioma Mortality in Japan Based on a Risk Function Tomoya MYOJIN 1, Kenichi AZUMA 2 *, Jiro OKUMURA 2 and Iwao UCHIYAMA 3 1 Department

More information

Estimation of the Number of Lung Cancer Cases Attributable to Asbestos Exposure

Estimation of the Number of Lung Cancer Cases Attributable to Asbestos Exposure Estimation of the Number of Lung Cancer Cases Attributable to Asbestos Exposure BC Asbestos Statistics Approximately 55,000 BC men and women exposed in 1971 in high exposed industries Significant exposure

More information

Francine Lortie-Monette, MD, MSc, CSPQ, MBA Department of Epidemiology and Biostatistics University of Western Ontario 2003

Francine Lortie-Monette, MD, MSc, CSPQ, MBA Department of Epidemiology and Biostatistics University of Western Ontario 2003 ASBESTOS Francine Lortie-Monette, MD, MSc, CSPQ, MBA Department of Epidemiology and Biostatistics University of Western Ontario 2003 Asbestosis Asbestosis is a model for other dust diseases as well as

More information

Descriptive Study of Mesothelioma in the Australian Capital Territory

Descriptive Study of Mesothelioma in the Australian Capital Territory Descriptive Study of Mesothelioma in the Australian Capital Territory Rosemary J. Korda, 1 Mark S. Clements, 2 Bruce K. Armstrong, 3,4 Susan M. Trevenar, 1 Martyn D. Kirk 1 1. National Centre for Epidemiology

More information

CONTINUING MEDICAL EDUCATION

CONTINUING MEDICAL EDUCATION ANZ J. Surg. 2004; 74: 931 934 CONTINUING MEDICAL EDUCATION CONTINUING MEDICAL EDUCATION CANCER STATISTICS: EVERYTHING YOU WANTED TO KNOW ABOUT THE CANCER REGISTRY DATA BUT WERE TOO AFRAID TO ASK GRAHAM

More information

EFFECT OF CHILDREN'S AGE AND LIFE EXPECTATION ON MESOTHELIOMA RISK 1

EFFECT OF CHILDREN'S AGE AND LIFE EXPECTATION ON MESOTHELIOMA RISK 1 EFFECT OF CHILDREN'S AGE AND LIFE EXPECTATION ON MESOTHELIOMA RISK 1 Robin Howie 2, Robin Howie Associates, Edinburgh It is generally accepted that the major risk from "low" level exposures to asbestos

More information

Statistical appendix. A.1 Introduction

Statistical appendix. A.1 Introduction A Statistical appendix A.1 Introduction This appendix contains contextual information to assist the interpretation of the performance indicators presented in the Report. The following four key factors

More information

The Burden of Occupational Lung Cancer Paul A. Demers, PhD

The Burden of Occupational Lung Cancer Paul A. Demers, PhD The Burden of Occupational Lung Cancer Paul A. Demers, PhD February 24 th, 2014 Measuring the Impact (burden) of Occupational Cancer Number or proportion of cancer deaths Number or proportion of new cancers

More information

ASBESTOS DISEASES. Dr Alastair Robertson

ASBESTOS DISEASES. Dr Alastair Robertson ASBESTOS DISEASES Dr Alastair Robertson Occupational Health Department University Hospital Birmingham Birmingham B29 6JF 01216278285 Alastair.robertson@uhb.nhs.uk Occupational Lung Disease Unit Birmingham

More information

australian mesothelioma registry

australian mesothelioma registry australian mesothelioma registry 1st Annual Report Mesothelioma in Australia 2011 The Australian Mesothelioma Registry is funded by Safe Work Australia and Comcare. Creative Commons ISBN 978-0-642-78563-3

More information

Key Work Health and Safety Statistics, Australia

Key Work Health and Safety Statistics, Australia Key Work Health and Safety Statistics, Australia 2013 Disclaimer The information provided in this document can only assist you in the most general way. This document does not replace any statutory requirements

More information

quick history of asbestos

quick history of asbestos quick history of asbestos 2500BC Asbestos used embalming Pharaohs and cooking pots. c100bc Roman historian Pliny notes illness and death for slaves wearing asbestos cloth 1880s Major asbestos mines open

More information

Toxicity of Amphibole Asbestos

Toxicity of Amphibole Asbestos Toxicity of Amphibole Asbestos Disclaimer: The material presented in these slides has been reviewed by the U.S. EPA and approved for presentation. Approval does not signify that the contents necessarily

More information

Asbestos Diseases. What Is Asbestos?

Asbestos Diseases. What Is Asbestos? 1 Asbestos Diseases What Is Asbestos? Asbestos is a term applied to a group of minerals formed into rock and mined in a similar way to coal. In this form, asbestos is made up of strong, fine and flexible

More information

Case-Referent Survey of Young Adults with Mesothelioma: II. Occupational Analyses

Case-Referent Survey of Young Adults with Mesothelioma: II. Occupational Analyses PerganiOIl PII: S000-878(01)0007- Ann. occup. Wv,?.. Vol., No. 7. pp. I9-2. 2001 CO 2001 British Occupational Hygiene Society Published by KIscvier Science Ltd. A]] rights reserved 000-878/01/20.00 Case-Referent

More information

Review of Eliminating occupational cancer in Europe and globally by J. Takala

Review of Eliminating occupational cancer in Europe and globally by J. Takala Review of Eliminating occupational cancer in Europe and globally by J. Takala There primary concerns of this manuscript are outlined below. More detail discussion of these points is presented on the following

More information

THE TIMES OF OCCURRENCE OF MESOTHELIOMAS IN RATS FOLLOWING INOCULATION WITH ASBESTOS

THE TIMES OF OCCURRENCE OF MESOTHELIOMAS IN RATS FOLLOWING INOCULATION WITH ASBESTOS 582 THE APPLICATION OF A MATHEMATICAL MODEL DESCRIBING THE TIMES OF OCCURRENCE OF MESOTHELIOMAS IN RATS FOLLOWING INOCULATION WITH ASBESTOS G. BERRY AND J. C. WAGNER From the Medical Research Council's

More information

(1) Comparison of studies with different follow-up periods

(1) Comparison of studies with different follow-up periods (1) Comparison of studies with different follow-up periods Is the absolute potency of amphiboles and relative potency of chrysotile underestimated because of studies with substantially incomplete follow-up?

More information

Asbestos Exposure and the Continuing Burden of Asbestos Related Disease. Paul A. Demers Partners in Prevention April, 2014

Asbestos Exposure and the Continuing Burden of Asbestos Related Disease. Paul A. Demers Partners in Prevention April, 2014 Asbestos Exposure and the Continuing Burden of Asbestos Related Disease Paul A. Demers Partners in Prevention April, 2014 Town of Asbestos, Quebec Source: http://en.wikipedia.org/wiki/asbestos,_quebec

More information

Asbestos and Mesothelioma in Ontario

Asbestos and Mesothelioma in Ontario Asbestos and Mesothelioma in Ontario May 29, 2010 CARWH Conference: Worker Health in a Changing world of work Loraine Marrett, PhD Outline Part I: Asbestos & its uses Part II: Asbestos & cancer Part III:

More information

Worldwide mesothelioma mortality trends

Worldwide mesothelioma mortality trends Worldwide mesothelioma mortality trends Harvard Symposium 24 th July 2009 Julian Peto London School of Hygiene and Tropical Medicine and Institute of Cancer Research Asbestos-related diseases Asbestosis

More information

The Trend in Airborne Asbestos Concentrations at Plants Manufacturing Asbestos-Containing Products in Japan

The Trend in Airborne Asbestos Concentrations at Plants Manufacturing Asbestos-Containing Products in Japan Industrial Health 2001, 39, 127 131 Original Article The Trend in Airborne Asbestos Concentrations at Plants Manufacturing Asbestos-Containing Products in Japan Koji YOSHIZUMI 1 *, Hajime HORI 2, Toshihiko

More information

Asbestos and Mesothelioma in Thailand

Asbestos and Mesothelioma in Thailand MD, DScMed, FRCP, FRACP, hon. FACP Emeritus Professor and Fellow of the Academy of Science, the Royal Institute of Thailand Abstract Chrysotile, a serpentile asbestos, has been used in a number of Thai

More information

ADVICE to safety representatives

ADVICE to safety representatives UNITE LEGAL SERVICES - TRUST YOUR UNION ADVICE to safety representatives Unite has launched a new asbestos campaign aiming to: Raise members awareness of asbestos hazards at work Provide advice to Unite

More information

The quantitative risks of mesothelioma and lung cancer in relation to asbestos exposure a comparison of risk models based on asbestos exposed cohorts

The quantitative risks of mesothelioma and lung cancer in relation to asbestos exposure a comparison of risk models based on asbestos exposed cohorts WATCH/2007/8 Annex 3 The quantitative risks of mesothelioma and lung cancer in relation to asbestos exposure a comparison of risk models based on asbestos exposed cohorts Introduction and aims 1. In 2000,

More information

Mesothelioma: Questions and Answers

Mesothelioma: Questions and Answers CANCER FACTS N a t i o n a l C a n c e r I n s t i t u t e N a t i o n a l I n s t i t u t e s o f H e a l t h D e p a r t m e n t o f H e a l t h a n d H u m a n S e r v i c e s Mesothelioma: Questions

More information

Master Builders Australia NATIONAL ASBESTOS MANAGEMENT CONTROL AND REMOVAL POLICY

Master Builders Australia NATIONAL ASBESTOS MANAGEMENT CONTROL AND REMOVAL POLICY Master Builders Australia NATIONAL ASBESTOS MANAGEMENT CONTROL AND REMOVAL POLICY 2013 Master Builders Australia Limited 2013. Master Builders Australia Limited ABN 68 137 130 182 Level 1, 16 Bentham Street

More information

Key Work Health and Safety Statistics, Australia

Key Work Health and Safety Statistics, Australia Key Work Health and Safety Statistics, Australia 2014 Disclaimer The information provided in this document can only assist you in the most general way. This document does not replace any statutory requirements

More information

B enign pleural disease (discrete plaques and pleural

B enign pleural disease (discrete plaques and pleural 665 ORIGINAL ARTICLE The additional risk of malignant mesothelioma in former workers and residents of Wittenoom with benign pleural disease or asbestosis A Reid, N de Klerk, G Ambrosini, N Olsen, S C Pang,

More information

australian mesothelioma registry

australian mesothelioma registry australian mesothelioma registry 2nd Annual Report Mesothelioma in Australia 2012 The Australian Mesothelioma Registry is funded by Safe Work Australia and Comcare. Creative Commons ISBN 978-1-74361-136-4

More information

Asbestos Review Program Update

Asbestos Review Program Update Asbestos Review Program Update Fraser Brims Respiratory Physician, SCGH Head of Occupational and Respiratory Health Unit, Institute for Lung Health, WA CCWA Lung Cancer: an update for 2015 Introduction

More information

Workers compensation for asbestos related disease in Canada

Workers compensation for asbestos related disease in Canada Workers compensation for asbestos related disease in Canada Katherine Lippel Canada Research Chair in Occupational Health and Safety Law University of Ottawa With the assistance of Valerie Kleinman, Friha

More information

HEALTH CARE FOR EXPOSURE TO ASBESTOS. 2010 The SafetyNet Centre for Occupational Health and Safety Research Memorial University www.safetynet.mun.

HEALTH CARE FOR EXPOSURE TO ASBESTOS. 2010 The SafetyNet Centre for Occupational Health and Safety Research Memorial University www.safetynet.mun. HEALTH CARE FOR PATIENTS WITH EXPOSURE TO ASBESTOS 2010 The SafetyNet Centre for Occupational Health and Safety Research Memorial University www.safetynet.mun.ca HEALTH CARE FOR PATIENTS WITH EXPOSURE

More information

Report of Working Groups

Report of Working Groups BD5.3 Report of Working Groups Elimination of Asbestos-related Diseases ICOH 2012 March 18, 2012 Cancun Report of WG Elimination of Asbestos-related Diseases Dr. Sherson mail to ICOH President of 7 December

More information

Mesothelioma in Northeastern Minnesota and Two Occupational Cohorts: 2007 Update. December 7, 2007

Mesothelioma in Northeastern Minnesota and Two Occupational Cohorts: 2007 Update. December 7, 2007 Mesothelioma in Northeastern Minnesota and Two Occupational Cohorts: 2007 Update December 7, 2007 Center for Occupational Health and Safety Chronic Disease and Environmental Epidemiology Section Minnesota

More information

Mesothelioma in Northeastern Minnesota and Two Occupational Cohorts: 2007 Update. December 7, 2007

Mesothelioma in Northeastern Minnesota and Two Occupational Cohorts: 2007 Update. December 7, 2007 Mesothelioma in Northeastern Minnesota and Two Occupational Cohorts: 2007 Update December 7, 2007 Center for Occupational Health and Safety Chronic Disease and Environmental Epidemiology Section Minnesota

More information

Plaintiffs Experts Latest Pathological Theories

Plaintiffs Experts Latest Pathological Theories Plaintiffs Experts Latest Pathological Theories Kurt B. Gerstner Campbell Campbell Edwards & Conroy, P.C. One Constitution Center Boston, MA 02129 (617) 241-3086 kgerstner@campbell-trial-lawyers.com Kurt

More information

australian mesothelioma registry

australian mesothelioma registry australian mesothelioma registry 3rd Annual Report Mesothelioma in Australia 2013 The Australian Mesothelioma Registry is funded by Safe Work Australia and Comcare. Creative Commons ISBN 978-1-74361-822-6

More information

Malignant Pleural Mesothelioma in Parts of Japan in Relationship to Asbestos Exposure

Malignant Pleural Mesothelioma in Parts of Japan in Relationship to Asbestos Exposure Industrial Health 2004, 42, 435 439 Original Article Malignant Pleural Mesothelioma in Parts of Japan in Relationship to Asbestos Exposure Takumi KISHIMOTO 1 *, Shinji OZAKI 1, Katsuya KATO 1, Hideyuki

More information

I I A C. INTERSTITIAL FIBROSIS IN COALWORKERS POSITION PAPER 17 THE INDUSTRIAL INJURIES ADVISORY COUNCIL. www.iiac.org.uk

I I A C. INTERSTITIAL FIBROSIS IN COALWORKERS POSITION PAPER 17 THE INDUSTRIAL INJURIES ADVISORY COUNCIL. www.iiac.org.uk I I A C. THE INDUSTRIAL INJURIES ADVISORY COUNCIL POSITION PAPER 17 INTERSTITIAL FIBROSIS IN COALWORKERS www.iiac.org.uk 1 INDUSTRIAL INJURIES ADVISORY COUNCIL PROFESSOR A J NEWMAN TAYLOR, CBE, FRCP, FFOM,

More information

Asbestos Related Diseases

Asbestos Related Diseases Asbestos Related Diseases Asbestosis Mesothelioma Lung Cancer Pleural Disease Asbestosis and Mesothelioma (LUNG CANCER) Support Group 1800 017 758 www.amsg.com.au ii Helping you and your family through

More information

Asbestos Diseases Uncovered

Asbestos Diseases Uncovered Asbestos Diseases Uncovered Your complete download & keep guide to asbestos-related diseases. Their symptoms, causes and potential compensation payable Contents What is Asbestos? What diseases are caused

More information

A Cross-Sectional Study of Asbestos- Related Morbidity and Mortality in Vermonters Residing Near an Asbestos Mine November 3, 2008

A Cross-Sectional Study of Asbestos- Related Morbidity and Mortality in Vermonters Residing Near an Asbestos Mine November 3, 2008 A Cross-Sectional Study of Asbestos- Related Morbidity and Mortality in Vermonters Residing Near an Asbestos Mine 108 Cherry Street, PO Box 70 Burlington, VT 05402 802.863.7200 healthvermont.gov A Cross-Sectional

More information

Asbestos Related Diseases. Asbestosis Mesothelioma Lung Cancer Pleural Disease. connecting raising awareness supporting advocating

Asbestos Related Diseases. Asbestosis Mesothelioma Lung Cancer Pleural Disease. connecting raising awareness supporting advocating Asbestos Related Diseases Asbestosis Mesothelioma Lung Cancer Pleural Disease connecting raising awareness supporting advocating 1800 017 758 www.asbestosassociation.com.au Asbestos lagging was widely

More information

Estimates of the impact of extending the scope of the Mesothelioma payment scheme. December 2013

Estimates of the impact of extending the scope of the Mesothelioma payment scheme. December 2013 Estimates of the impact of extending the scope of the Mesothelioma payment scheme December 2013 Contents Introduction... 6 Background... 7 Estimated volumes and costs if the scheme started on particular

More information

PREDICTION OF CANCER MORTALITY BY EVALUATION OF ASBESTOS FIBERS CONCENTRATIONS IN AN ASBESTOS-CEMENT PRODUCTS FACTORY

PREDICTION OF CANCER MORTALITY BY EVALUATION OF ASBESTOS FIBERS CONCENTRATIONS IN AN ASBESTOS-CEMENT PRODUCTS FACTORY Iran. J. Environ. Health. Sci. Eng., 21, Vol. 7, No. 2, pp. 165-172 PREDICTION OF CANCER MORTALITY BY EVALUATION OF ASBESTOS FIBERS CONCENTRATIONS IN AN ASBESTOS-CEMENT PRODUCTS FACTORY 1 M. J. Jafari,

More information

Carcinogens in the Construction Industry

Carcinogens in the Construction Industry Carcinogens in the Construction Industry BENGT JÄRVHOLM Department of Public Health and Clinical Medicine, Umeå University, SE-901 85 Umeå, Sweden ABSTRACT: The construction industry is a complex work

More information

ASBESTOS-RELATED DISEASE INDICATORS

ASBESTOS-RELATED DISEASE INDICATORS ASBESTOS-RELATED DISEASE INDICATORS May 2014 Safe Work Australia Asbestos-related Disease Indicators May 2014 Disclaimer The information provided in this document can only assist you in the most general

More information

Occupational Characteristics of Cases with Asbestosrelated Diseases in The Netherlands

Occupational Characteristics of Cases with Asbestosrelated Diseases in The Netherlands Ann. occup. Hyg., Vol. 47, No. 6, pp. 485 492, 2003 2003 British Occupational Hygiene Society Published by Oxford University Press DOI: 10.1093/annhyg/meg062 Occupational Characteristics of Cases with

More information

ASBESTOS. Know what it is and how you can protect yourself. environmental affairs Department: Environmental Affairs REPUBLIC OF SOUTH AFRICA

ASBESTOS. Know what it is and how you can protect yourself. environmental affairs Department: Environmental Affairs REPUBLIC OF SOUTH AFRICA ASBESTOS Know what it is and how you can protect yourself environmental affairs Department: Environmental Affairs REPUBLIC OF SOUTH AFRICA 1 What is asbestos? The term asbestos designates a group of naturally

More information

research report 53 Dental decay among Australian children This report provides information on the dental decay experience of Australian Main findings

research report 53 Dental decay among Australian children This report provides information on the dental decay experience of Australian Main findings AIHW Dental Statistics and Research Unit Research report 53 July 2011 Dental decay among Australian children This report provides information on the dental decay experience of Australian children from

More information

A Conference on Asbestos & Mesothelioma

A Conference on Asbestos & Mesothelioma A Conference on Asbestos & Mesothelioma May 3 rd 4 th, 2010 Las Vegas, NV Encore, a Wynn Hotel Faculty Jerrold Abraham Wayne Berman David Bernstein Arnold Brody Andrew Churg David Egilman Murray Finklestein

More information

Asbestos risks, safety and its role in lung disease

Asbestos risks, safety and its role in lung disease Asbestos risks, safety and its role in lung disease Fraser Brims Respiratory Physician, SCGH Head of Occupa9onal and Respiratory Health Unit, Ins9tute for Lung Health, WA Lung Founda9on Australia Educa9on

More information