HISTORICAL PERSPECTIVE TOBACCO AND CANCER AACR MEMBERS AND JOURNALS LED PIONEERING RESEARCH

Size: px
Start display at page:

Download "HISTORICAL PERSPECTIVE TOBACCO AND CANCER AACR MEMBERS AND JOURNALS LED PIONEERING RESEARCH"

Transcription

1 1912 Isaac Adler (AACR member) writes the first monograph drawing attention to primary lung cancer, which in the early 20th century was considered a rare cancer, and suggests lung cancer is related to smoking based on its increasing occurrence in men rather than women, as women rarely smoked (1) A popular author, Samuel Hopkins Adams, writes an article on cancer for The Ladies Home Journal in which he notes the association between pipe smoking and lip cancer. The article was commissioned by AACR member Thomas S. Cullen, with the endorsement of the AACR Council, and was one of the first public discussions of cancer in a lay publication (2). Thomas S. Cullen, MD ( ) 1921 Joseph C. Bloodgood (AACR member) collects data to show that nearly all of his male patients with cancer of the tongue used tobacco (3). Bloodgood was a multitalented physician who worked in several specialties as well as serving on the AACR Council. Joseph C. Bloodgood, MD ( ) 1924 At the AACR Annual Meeting, Frederick L. Hoffman (AACR member) reports statistics showing a link between smoking and cancer (4); the abstract appears in AACR s Journal of Cancer Research. Seven years later, he writes a formal report linking heavy smoking to cancers of the mouth and lungs. Hoffman was a founder of the American Cancer Society. Frederick L. Hoffman, LLD ( )

2 1924 Sir Ernest L. Kennaway (AACR member) publishes a paper identifying substances in tar that cause cancer. He continues to publish studies on the incidence of cancer of the lungs and larynx throughout the 1930s and 1940s (6). Sir Ernest L. Kennaway, MD, DSc ( ) A series of articles on the harmful effects of tobacco by Angel H. Roffo (AACR member), from the Cancer Institute in Buenos Aires, appears primarily in German journals. Hitler later used these articles to launch his antitobacco campaign (7). Roffo is recognized at the end of the 20th century as one of the fathers of carcinogenesis. Angel H. Roffo, MD ( ) 1932 AACR s journal, the American Journal of Cancer, publishes two consecutive articles showing a likely association between smoking and cancer. These articles are cited decades later as evidence against tobacco companies (8, 9) Inhaling tobacco smoke did not become widespread until flue curing, a new process, made inhaling tolerable. Surgeons Alton Oschner and Michael E. DeBakey (AACR member) reported a strong link between inhaled smoke and lung cancer (10). Michael E. DeBakey, MD ( )

3 1941 Curtis M. Flory (AACR member) publishes an extensive review of tobacco tars and cancer in the first volume of Cancer Research (11). This article was part of his doctoral dissertation and was widely reprinted after its appearance in the journal At the AACR Annual Meeting, Harold L. Stewart (AACR member) and colleagues report one of the earliest studies using a smoking machine to test the effects of smoke on experimental and control mice (12). Such machines became a concern for animal rights advocates, primarily because of experiments in beagles, although smoking machines are still used in research. Harold L. Stewart, MD ( ) Morton L. Levin (AACR member) and colleagues conduct a case-control study, using patient data collected at Roswell Park Cancer Institute, to show the link between cancer and tobacco (13). Roswell Park later devoted considerable resources to studying the effects of smoking, even growing its own organic tobacco for study purposes. While he was still a medical student, Ernest L. Wynder (AACR member) convinced surgeon Evarts A. Graham to join him in conducting a case-control study, which shows a strong association between cigarette smoking and lung cancer (14). Graham, a 50-year smoker, quit based on the findings, but it was too late, and he died of lung cancer. Ernest L. Wynder, MD ( )

4 Sir Richard Doll ( AACR member) and A. Bradford Hill conduct a case-control study at about the same time as that of Wynder and Graham, although the Doll/Hill study is published later (15). British and Canadian public officials are quicker to make recommendations based on the findings than are U.S. officials. Sir Richard Doll, MD ( ) An early review by Robert Schrek (AACR Member) and coauthors (16) in Cancer Research covers the research to date linking smoking to cancer. Cancer Research publishes a casecontrol study (17) conducted in two U.S. cities that shows the correlation between cigarette smoking and respiratory tract cancer and cigar and pipe smoking and buccal cancer Pathologist Oscar Auerbach (AACR member) and coauthors are the first to report (18) an experimental method to study autopsy findings in smokers, findings that show precancerous pathology. Auerbach s studies of damaged cells are widely viewed as definitive evidence of smoking s effects and are more respected than statistical and observational studies. Oscar Auerbach, MD ( ) 1956 An advocate of smoking, AACR Member Clarence C. Little writes a guest editorial in Cancer Research asserting that a link between smoking and cancer has not been established (19). Evarts Graham rebuts (20, 21) and points out that Little chairs the Scientific Advisory Board of the Tobacco Industry Research Committee. AACR reconsiders its policy on guest editorials. Clarence C. Little, DSc ( )

5 1957 In an extensive response to criticism that insufficient animal experiments have been done to prove the association between tar and cancer, Graham, Chroninger, and Wynder report in Cancer Research the last part of their four-part series on evidence from animal experiments (22) Michael B. Shimkin (AACR member) is the NCI representative to the Study Group on Smoking and Health. Their report (23), issued 7 years before the 1964 Surgeon General s Report, states that evidence linking tobacco and cancer is unequivocal. Shimkin later remarks that if spinach were as bad for people as tobacco, it would already have been banned (Washington Star, 1961). Michael B. Shimkin, MD ( ) 1958 In a Cancer Research paper, Alfred A. Gellhorn (AACR member) demonstrates the effect of cigarette tar in causing cancer (24). These findings from an important researcher who was not previously involved in tobacco studies add considerably more weight to the evidence. Alfred A. Gellhorn, MD ( ) 1962 Surgeon General Luther Terry appoints a committee to assemble evidence on tobacco and cancer. Five of the 10 scientists appointed are AACR members (Stanhope Bayne-Jones, Louis Fieser, Jacob Furth, Walter Burdette, and Emanuel Farber). Their work takes over 2 years and is considered the most comprehensive review of evidence to date.

6 References Most of the articles in this list were cited in the 1964 Surgeon General s report. 1. Adler IA. Primary Malignant Growths of the Lung and Bronchi: A Pathological and Clinical Study, New York: Longmans, Green and Company, Adams SH. What can we do about cancer? The most vital and insistent question in the medical world. Ladies Home Journal, May 1913; 30(5): Bloodgood JC. Cancer of the tongue; a preventable disease. JAMA 1921;77: Hoffman FC. The causation of cancer, In: Proceedings of the American Association for Cancer Research, Seventeenth Annual Meeting, April 17, 1924, Boston, MA. J Cancer Res. 1924;8: Hoffman F.L. Cancer and smoking habits. Ann Surg 1931;93: Kennaway EL. The formation of a cancer-producing substance from isoprene (2-methyl-butadiene). J Path Bact 1924;27: Research summarized in: Roffo AH. The carcinogenic effects of tobacco (German). Monatsschrift für Krebsbekampfüng 1940;8(5). Reproduced in Bull WHO 2006;84(6): McNally WD. The tar in cigarette smoke and its possible effects. Am J Cancer 1932;16; Bogen E, Loomis RN. Tobacco tar: experimental investigation of its alleged carcinogenic action. Am J Cancer 1932;16: Oschner A, DeBakey M. Primary pulmonary malignancy. Treatment by total pneumonectomy. Surg Gynecol Obstet 1939;68: Flory, CM. The production of tumors by tobacco tars. Cancer Res 1941;1: Levin ML, Goldstein H, Gerhardt PR. Cancer and tobacco smoking: A preliminary report. JAMA ;143: Wynder EL, Graham EA. Tobacco smoking as a possible etiologic factor in bronchogenic carcinoma: a study of 684 proved cases. JAMA ;143: Doll R, Hill AB. Smoking and carcinoma of the lung. Preliminary report. Br Med J ;2: Schrek, R, Baker LA, Ballard GP, Dolgoff S. Tobacco smoking as an etiologic factor of disease. Cancer Res ;10: Mills CA, Porter MM. Tobacco smoking habits and cancer of the mouth and respiratory system. Cancer Res ;10: Auerbach O, Petrick TG, Stout AP, et al. The anatomical approach to the study of smoking and bronchogenic carcinoma: A preliminary report of forty-one cases. Cancer 1956;9: Little CC. Smoking and lung cancer [guest editorial]. Cancer Res 1956; 16: Graham EA. To the editor of Cancer Research [letter]. Cancer Res 1956;16: Little CC. To the editor of Cancer Research [letter]. Cancer Res 1956;16:817-8.) 22. Graham EA, Croninger AB, Wynder EL. Experimental production of carcinoma with cigarette tar. IV. Successful experiments with rabbits. Cancer Res 1957;17: Joint Report of the Study Group on Smoking and Health. Smoking and Health. Science 1957;125: Gellhorn A. The cocarcinogenic activity of cigarette tobacco tar. Cancer Res 1958;18: Lorenz E, Stewart HL, Daniel JH, Nelson CV. The effects of breathing tobacco smoke on strain A mice (abstract). In: Proceedings American Association for Cancer Research. Cancer Res 1943;3:122-4.

Public Health Classics. Bulletin of the World Health Organization June 2006, 84 (6)

Public Health Classics. Bulletin of the World Health Organization June 2006, 84 (6) Public Health Classics Bulletin of the World Health Organization June 2006, 84 (6) 497 Public Health Classics 498 Bulletin of the World Health Organization June 2006, 84 (6) Public Health Classics Bulletin

More information

Identification of Non-Smokers for the Workers Compensation Board of Manitoba Lung Cancer and Fire Fighting Policy

Identification of Non-Smokers for the Workers Compensation Board of Manitoba Lung Cancer and Fire Fighting Policy Identification of Non-Smokers for the Workers Compensation Board of Manitoba Lung Cancer and Fire Fighting Policy Submitted by Allen Kraut, MD, FRCPC Associate Professor Departments of Internal Medicine

More information

Case-Control Studies. Sukon Kanchanaraksa, PhD Johns Hopkins University

Case-Control Studies. Sukon Kanchanaraksa, PhD Johns Hopkins University This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this

More information

Neurobiology of Addiction and 12-step Recovery

Neurobiology of Addiction and 12-step Recovery Neurobiology of Addiction and 12-step Recovery Luis Giuffra, MD, PhD Professor of Clinical Psychiatry Washington University in St. Louis www.claytonbehavioral.com William Silkworth,MD Alcoholism is: An

More information

Smoking and Lung Cancer

Smoking and Lung Cancer Smoking and Lung Cancer Objectives! Students should be able to identify some of the other consequences of smoking other than lung cancer! Students should be able to identify the effects of the chemicals

More information

ORAL SQUAMOUS CELL CARCINOMA

ORAL SQUAMOUS CELL CARCINOMA Objectives ORAL SQUAMOUS CELL CARCINOMA Important Issues Epidemiology of oral cancer Etiology and risk factors of oral cancer Clinical presentation of oral cancer Components of an Oral Cancer clinical

More information

Andrews Publications Tobacco Litigation 2000 THEORIES FOR THE REDUCTION OF DAMAGES

Andrews Publications Tobacco Litigation 2000 THEORIES FOR THE REDUCTION OF DAMAGES THEORIES FOR THE REDUCTION OF DAMAGES By Steven Wright Brita J. Forssberg SYNERGISM Effect of cigarette smoking is greater than that of asbestos. Synergism Synergism Lung cancer incidence rates, expressed

More information

Lung Cancer. This reference summary will help you better understand lung cancer and the treatment options that are available.

Lung Cancer. This reference summary will help you better understand lung cancer and the treatment options that are available. Lung Cancer Introduction Lung cancer is the number one cancer killer of men and women. Over 165,000 people die of lung cancer every year in the United States. Most cases of lung cancer are related to cigarette

More information

Lung Cancer. American Cancer Society

Lung Cancer. American Cancer Society Lung Cancer American Cancer Society Reviewed March 2016 What we ll be talking about How common is lung cancer? What is lung cancer? The 2 main types of lung cancer Causes of lung cancer What are the risk

More information

Diagnosis and Treatment of Common Oral Lesions Causing Pain

Diagnosis and Treatment of Common Oral Lesions Causing Pain Diagnosis and Treatment of Common Oral Lesions Causing Pain John D. McDowell, DDS, MS University of Colorado School of Dentistry Chair, Oral Diagnosis, Medicine and Radiology Director, Oral Medicine and

More information

Unit 14: The Question of Causation

Unit 14: The Question of Causation Unit 14: The Question of Causation Summary of Video Causation in statistics can be a tricky thing because appearances can often be deceiving. Observing an association between two variables does not automatically

More information

Facing Lung Cancer? Learn why da Vinci Surgery may be your best treatment option for lung cancer.

Facing Lung Cancer? Learn why da Vinci Surgery may be your best treatment option for lung cancer. Facing Lung Cancer? Learn why da Vinci Surgery may be your best treatment option for lung cancer. The Condition: Lung Cancer The lung is the organ that moves oxygen through your body. You have two lungs

More information

Substance Abuse. Health Equity Highlight: Adolescents

Substance Abuse. Health Equity Highlight: Adolescents Substance Abuse 108 Background The deliberate use and overuse of harmful substances has a serious impact on the quality of life of Maine people. As a result of substance abuse, the lives of Maine residents

More information

Plaintiffs Experts Latest Pathological Theories

Plaintiffs Experts Latest Pathological Theories Plaintiffs Experts Latest Pathological Theories Kurt B. Gerstner Campbell Campbell Edwards & Conroy, P.C. One Constitution Center Boston, MA 02129 (617) 241-3086 kgerstner@campbell-trial-lawyers.com Kurt

More information

Why Cigarettes are bad

Why Cigarettes are bad Why Cigarettes are bad Smoking should be illegal for many reasons. Firstly, they not only affect the user themselves but they also affect their surroundings. These including the environment and the people

More information

HANDLING LUNG CANCER CLAIMS

HANDLING LUNG CANCER CLAIMS HANDLING LUNG CANCER CLAIMS JENNIFER S. KILPATRICK SWANSON, MARTIN & BELL, LLP 330 North Wabash Avenue Suite 3300 Chicago, Illinois 60611-3604 (312) 321-3517 (312) 321-0990 jkilpatrick@smbtrials.com 1

More information

BE SMOKE FREE CUT YOUR CANCER RISK

BE SMOKE FREE CUT YOUR CANCER RISK BE SMOKE FREE CUT YOUR CANCER RISK cruk.org cruk.org As many as 2 out of 3 long-term smokers die from smoking-related illnesses, including cancer, heart and lung diseases. But it is never too late to stop.

More information

National Framework for Excellence in

National Framework for Excellence in National Framework for Excellence in Lung Cancer Screening and Continuum of Care declaration of purpose Rights and Expectations THE RIGHTS OF THE PEOPLE Lung cancer kills more Americans than the next four

More information

Health Insurance Benefits for Treatment of Tobacco Dependence. Summary

Health Insurance Benefits for Treatment of Tobacco Dependence. Summary S U M M A R Y R E P O R T O F T H E P A C I F I C C E N T E R O N H E A L T H A N D T O B A C C O Health Insurance Benefits for Treatment of Tobacco Dependence Summary $ Why do tobacco users need health

More information

Stephen R. Veach, M.D.

Stephen R. Veach, M.D. Stephen R. Veach, M.D. Memorial Sloan-Kettering Cancer Center International Oncology Programs 160 E. 53 rd Street New York, NY 10022 212-610 610-08780878 - tel 212-308 308-7063 - fax veachs@mskcc.org SCREENING

More information

Lung Cancer: Diagnosis, Staging and Treatment

Lung Cancer: Diagnosis, Staging and Treatment PATIENT EDUCATION patienteducation.osumc.edu Lung Cancer: Diagnosis, Staging and Treatment Cancer begins in our cells. Cells are the building blocks of our tissues. Tissues make up the organs of the body.

More information

Luther L. Terry Papers

Luther L. Terry Papers UPT 50 T329 Finding aid prepared by J.M. Duffin. Last updated on November 05, 2013. University of Pennsylvania, University Archives and Records Center June 2000 Table of Contents Summary Information...3

More information

Uses and Abuses of Pathology in Asbestos-exposed Populations

Uses and Abuses of Pathology in Asbestos-exposed Populations Uses and Abuses of Pathology in Asbestos-exposed Populations Jerrold L. Abraham, MD Department of Pathology State University of New York Upstate Medical University Syracuse, NY, 13210 USA The term: Asbestosis,

More information

Smoking Cessation Program

Smoking Cessation Program Smoking Cessation Program UHN Information for people who are ready to quit smoking Read this information to learn: why you should quit smoking how the Smoking Cessation Program works treatments to help

More information

Disease/Illness GUIDE TO ASBESTOS LUNG CANCER. What Is Asbestos Lung Cancer? www.simpsonmillar.co.uk Telephone 0844 858 3200

Disease/Illness GUIDE TO ASBESTOS LUNG CANCER. What Is Asbestos Lung Cancer? www.simpsonmillar.co.uk Telephone 0844 858 3200 GUIDE TO ASBESTOS LUNG CANCER What Is Asbestos Lung Cancer? Like tobacco smoking, exposure to asbestos can result in the development of lung cancer. Similarly, the risk of developing asbestos induced lung

More information

HPV and Head Neck Cancer

HPV and Head Neck Cancer HPV and Head Neck Cancer Becky Massey, MD Assistant Professor Division of Head and Neck Surgical Oncology and Reconstruction Department of Otolaryngology & Communication Sciences Medical College of Wisconsin

More information

GLOBAL CONCERNS ABOUT HPV VACCINES FACT SHEET

GLOBAL CONCERNS ABOUT HPV VACCINES FACT SHEET GLOBAL CONCERNS ABOUT HPV VACCINES FACT SHEET When detected, HPV infection is easily managed and rarely proceeds to cancer Very few women with HPV develop cervical cancer HPV infections are only one of

More information

MANCHESTER Lung Cancer Screening Program Dartmouth-Hitchcock Manchester 100 Hitchcock Way Manchester, NH 03104 (603) 695-2850

MANCHESTER Lung Cancer Screening Program Dartmouth-Hitchcock Manchester 100 Hitchcock Way Manchester, NH 03104 (603) 695-2850 LEBANON Lung Cancer Screening Program One Medical Center Drive Lebanon, NH 03756 (603) 650-4400 (866) 966-1601 Toll-free cancer.dartmouth.edu/lungscreening MANCHESTER Lung Cancer Screening Program Dartmouth-Hitchcock

More information

Radon and Cancer: Questions and Answers

Radon and Cancer: Questions and Answers Radon and Cancer: Questions and Answers Key Points Radon is a radioactive gas released from the normal decay of uranium in rocks and soil (see Question 1). Radioactive particles from radon can damage cells

More information

Talcum Powder and Cancer

Talcum Powder and Cancer Talcum Powder and Cancer What is talcum powder? Talcum powder is made from talc, a mineral made up mainly of the elements magnesium, silicon, and oxygen. As a powder, it absorbs moisture well and helps

More information

Kentucky Lung Cancer Research Program. 2010 Strategic Plan Update

Kentucky Lung Cancer Research Program. 2010 Strategic Plan Update Kentucky Lung Cancer Research Program 2010 Strategic Plan Update Approved by the KLCR Program Governance Board August 12, 2009 KLCR Program Strategic Plan Table of Contents Introduction... 3 GOAL 1: Investigator-Initiated

More information

Mesothelioma: Questions and Answers

Mesothelioma: Questions and Answers CANCER FACTS N a t i o n a l C a n c e r I n s t i t u t e N a t i o n a l I n s t i t u t e s o f H e a l t h D e p a r t m e n t o f H e a l t h a n d H u m a n S e r v i c e s Mesothelioma: Questions

More information

Smoking and your heart health

Smoking and your heart health Smoking and your heart health Key points about smoking and your heart health Smoking kills more than 22,000 Australians a year. 1 Breathing other people s smoke (second-hand smoke) is harmful to smokers

More information

Lungenkrebs. Lungenkrebs Häufigkeit

Lungenkrebs. Lungenkrebs Häufigkeit Lungenkrebs Prof. Dr. E.W. Russi Pneumologie 1.9.2008 Lungenkrebs Häufigkeit The Principles and Practice of Medicine William Osler New York D. Appleton and Company 1892 Section IV DISEASE OF THE RESPIRATORY

More information

Lung Cancer: Diagnosis, Staging and Treatment

Lung Cancer: Diagnosis, Staging and Treatment PATIENT EDUCATION patienteducation.osumc.edu Lung Cancer: Diagnosis, Staging and Treatment Cancer starts in our cells. Cells are the building blocks of our tissues. Tissues make up the organs of the body.

More information

Why is radon a health problem?

Why is radon a health problem? Lesson 2 Why is radon a health problem? and lung cancer is largest source of radiation exposure to general public is leading cause of lung cancer among nonsmokers Only cigarette smoking causes more deaths

More information

Scientific Update on Safe Use of Asbestos. Robert P. Nolan, PhD International Environmental Research Foundation New York, New York www.ierfinc.

Scientific Update on Safe Use of Asbestos. Robert P. Nolan, PhD International Environmental Research Foundation New York, New York www.ierfinc. Scientific Update on Safe Use of Asbestos Robert P. Nolan, PhD International Environmental Research Foundation New York, New York www.ierfinc.org When We Talk about Asbestos What Do We Mean? Anthophyllite

More information

Lung Cancer. Public Outcomes Report. Submitted by Omar A. Majid, MD

Lung Cancer. Public Outcomes Report. Submitted by Omar A. Majid, MD Public Outcomes Report Lung Cancer Submitted by Omar A. Majid, MD Lung cancer is the most common cancer-related cause of death among men and women. It has been estimated that there will be 226,1 new cases

More information

Lung Cancer Screening

Lung Cancer Screening Scan for mobile link. Lung Cancer Screening What is lung cancer screening? Screening examinations are tests performed to find disease before symptoms begin. The goal of screening is to detect disease at

More information

Appendix: List of Contributors

Appendix: List of Contributors Appendix: List of Contributors Editorial Board Kaveh G. Shojania, MD Assistant Professor Bradford W. Duncan, MD AHRQ Patient Safety Fellow Center for Primary Care & Outcomes Research Stanford University

More information

U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE Public Health Service Office of the Assistant Secretary for Health Office on Smoking and Health

U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE Public Health Service Office of the Assistant Secretary for Health Office on Smoking and Health U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE Public Health Service Office of the Assistant Secretary for Health Office on Smoking and Health The Health Consquences of SMOKING CtEVV Publication No.

More information

co-sponsored by the Health & Physical Education Department, the Health Services Office, and the Student Development Center

co-sponsored by the Health & Physical Education Department, the Health Services Office, and the Student Development Center Cancer is a group of more than 100 related diseases. Normally, cells grow and divide to produce more cells to keep the body healthy. Sometimes, this process goes wrong. New cells form when the body doesn

More information

Tissue Banking. Advancing Cancer Care

Tissue Banking. Advancing Cancer Care Tissue Banking Advancing Cancer Care Acknowledgments Producer Director Writer Photographer Designer Christina M. Parker, MD Dana-Farber Cancer Institute, Inc. David H. Rose POV-Rose Films Lonnie K. Christiansen

More information

Oral health and smoking Information for you

Oral health and smoking Information for you Oral health and smoking Information for you Visit our website: www.nhsaaa.net All our publications are available in other formats How can smoking affect my oral health? Most people are now aware that smoking

More information

evaluation of cancer hazards Robert A Baan PhD The IARC MONOGRAPHS International Agency for Research on Cancer Lyon, France

evaluation of cancer hazards Robert A Baan PhD The IARC MONOGRAPHS International Agency for Research on Cancer Lyon, France Consumption of alcoholic beverages; evaluation of cancer hazards Robert A Baan PhD The IARC MONOGRAPHS International Agency for Research on Cancer Lyon, France The IARC Monographs The IARC Monographs are

More information

Carcinogens in the Construction Industry

Carcinogens in the Construction Industry Carcinogens in the Construction Industry BENGT JÄRVHOLM Department of Public Health and Clinical Medicine, Umeå University, SE-901 85 Umeå, Sweden ABSTRACT: The construction industry is a complex work

More information

"Starting today, every doctor, nurse, health plan, purchaser, and medical school in America should make treating tobacco dependence a top priority.

Starting today, every doctor, nurse, health plan, purchaser, and medical school in America should make treating tobacco dependence a top priority. Encouraging Tobacco Cessation Through the Five A s: Ask, Advise, Assess, Assist, Arrange Mary Clare Champion, Ph.D. Tennessee Primary Care Clinical Conference April 14-15, 2011 Franklin, TN "Starting today,

More information

The Forzani MacPhail Colon Cancer Screening Centre Frequently Asked Questions. What is the Forzani MacPhail Colon Cancer Screening Centre?

The Forzani MacPhail Colon Cancer Screening Centre Frequently Asked Questions. What is the Forzani MacPhail Colon Cancer Screening Centre? The Forzani MacPhail Colon Cancer Screening Centre Frequently Asked Questions What is the Forzani MacPhail Colon Cancer Screening Centre? The Forzani and MacPhail Colon Cancer Screening Centre (CCSC) is

More information

Health Science / Anatomy Exam 1 Study Guide

Health Science / Anatomy Exam 1 Study Guide THIS EXAM WILL ONLY COVER ALCOHOL AND TOBACCO LECTURES Alcohol What is Alcohol? Alcohol is a depressant Contains intoxicating substance called ethyl alcohol or ethanol Alcohol use Approximately 59.8% of

More information

Fulfilling the Promise

Fulfilling the Promise Fulfilling the Promise Advancing the Fight Against Cancer: America s Medical Schools and Teaching Hospitals For more than a century, the nation s medical schools and teaching hospitals have worked to understand,

More information

NHS Barking and Dagenham Briefing on disease linked to Asbestos in Barking & Dagenham

NHS Barking and Dagenham Briefing on disease linked to Asbestos in Barking & Dagenham APPENDIX 1 NHS Barking and Dagenham Briefing on disease linked to Asbestos in Barking & Dagenham 1. Background 1.1. Asbestos Asbestos is a general name given to several naturally occurring fibrous minerals

More information

Nebraska High School Youth Tobacco Survey. Results. May 2010

Nebraska High School Youth Tobacco Survey. Results. May 2010 Nebraska High School Youth Tobacco Survey 2008 Results May 2010 Nebraska High School Youth Tobacco Survey 2008* Introduction The Nebraska High School Youth Tobacco Survey (YTS) was first conducted in 2000.

More information

2012 CANCER PROGRAM ANNUAL REPORT

2012 CANCER PROGRAM ANNUAL REPORT MERCY REGIONAL CANCER CENTER 2012 CANCER PROGRAM ANNUAL REPORT Using 2011 Data Mercy Regional Cancer Center When you have cancer, you might think first of treatments chemotherapy and radiation. You want

More information

Causal Association. Sukon Kanchanaraksa, PhD Johns Hopkins University

Causal Association. Sukon Kanchanaraksa, PhD Johns Hopkins University This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this

More information

No One Deserves Lung Cancer PROJECT LUNG CANCER. Fighting For Air

No One Deserves Lung Cancer PROJECT LUNG CANCER. Fighting For Air No One Deserves Lung Cancer PROJECT LUNG CANCER Fighting For Air PROJECT LUNG CANCER l 2 Facing the Facts About Lung Cancer Lung cancer is the single leading cause of cancer death in the country. Lung

More information

TOBACCO USE AMONG AFRICAN AMERICANS

TOBACCO USE AMONG AFRICAN AMERICANS TOBACCO USE AMONG AFRICAN AMERICANS Each year, approximately 45,000 African Americans die from smoking-related disease. 1 Smoking-related illnesses are the number one cause of death in the African-American

More information

GRADE 11F: Biology 3. UNIT 11FB.3 9 hours. Human gas exchange system and health. Resources. About this unit. Previous learning.

GRADE 11F: Biology 3. UNIT 11FB.3 9 hours. Human gas exchange system and health. Resources. About this unit. Previous learning. GRADE 11F: Biology 3 Human gas exchange system and health UNIT 11FB.3 9 hours About this unit This unit is the third of six units on biology for Grade 11 foundation. The unit is designed to guide your

More information

PROSTATE CANCER. Straight Talk for African-American Men and Their Families

PROSTATE CANCER. Straight Talk for African-American Men and Their Families PROSTATE CANCER Straight Talk for African-American Men and Their Families No Man is Invincible There have been lots of ups and downs in my life s journey, but nothing to prepare me for those four echoing

More information

Asbestos related cancers

Asbestos related cancers New cancer cases 1954-215 in Finland, Men Pukkala et al. 26 Asbestos related cancers Panu Oksa, MD, docent Course on asbestos-related diseases Tartu 4-5.12.26 Asbestos related cancer / FIOH / PO / 1.1.27

More information

LCFA/IASLC LORI MONROE SCHOLARSHIP IN TRANSLATIONAL LUNG CANCER RESEARCH

LCFA/IASLC LORI MONROE SCHOLARSHIP IN TRANSLATIONAL LUNG CANCER RESEARCH LCFA/IASLC LORI MONROE SCHOLARSHIP IN TRANSLATIONAL LUNG CANCER RESEARCH FUNDING OPPORTUNITY DESCRIPTION 2016 REQUEST FOR APPLICATION (RFA) Lung Cancer Foundation of America (LCFA) and the International

More information

RESPIRATORY DISEASE AND SMOKE EXPOSURE QUESTIONNAIRE

RESPIRATORY DISEASE AND SMOKE EXPOSURE QUESTIONNAIRE RESPIRATORY DISEASE AND SMOKE EXPOSURE QUESTIONNAIRE COPDGene THIS FORM DOES NOT NEED TO BE COMPLETED IF THE SUBJECT IS WITHIN WINDOW FROM COPDGene VISIT 0a) Date... / / 0b) Initials... Instructions: This

More information

Helpful Information for People With Non Small Cell Lung Cancer and Their Families. WHAT YOU SHOULD KNOW ABOUT Advanced Non Small Cell Lung Cancer

Helpful Information for People With Non Small Cell Lung Cancer and Their Families. WHAT YOU SHOULD KNOW ABOUT Advanced Non Small Cell Lung Cancer Helpful Information for People With Non Small Cell Lung Cancer and Their Families WHAT YOU SHOULD KNOW ABOUT Advanced Non Small Cell Lung Cancer Learning the basics of non small cell lung cancer If you

More information

Grade. Lesson 12. Substance Abuse Prevention: Tobacco and Marijuana

Grade. Lesson 12. Substance Abuse Prevention: Tobacco and Marijuana Substance Abuse Prevention: Tobacco and Marijuana Handout 12A: Facts About Tobacco Tobacco and Addiction Tobacco is as addictive as heroin or cocaine. 30 You can start feeling addicted after smoking only

More information

Lung Cancer Multidisciplinary Meeting Toolkit. National Lung Cancer Working Group

Lung Cancer Multidisciplinary Meeting Toolkit. National Lung Cancer Working Group Lung Cancer Multidisciplinary Meeting Toolkit National Lung Cancer Working Group September 2014 Contents Introduction 1 Multidisciplinary meetings 1 Toolkit for implementing high-quality lung cancer MDMs

More information

Treatment Guide Lung Cancer Management

Treatment Guide Lung Cancer Management Treatment Guide Lung Cancer Management The Chest Cancer Center at Cleveland Clinic, which includes specialists from the Respiratory Institute, Taussig Cancer Institute and Miller Family Heart & Vascular

More information

Tobacco and the global lung cancer epidemic

Tobacco and the global lung cancer epidemic to lung cancer in the mouse. Nature Genet. 14, 465 467 (1996). 57. Wright, S. Genic and organismic selection. Evolution 34, 825 843 (1980). 58. Kinzler, K. W. & Vogelstein, B. Gatekeepers and caretakers.

More information

A New Anti-inflammatory Therapy For COPD

A New Anti-inflammatory Therapy For COPD A New Anti-inflammatory Therapy For COPD A Brief Introduction to COPD Current Treatment of COPD Corticosteroid Resistant Chronic Inflammation Looking For New Anti-inflammatory Therapy Introduction to Moxibustion

More information

Prevent what is preventable, cure what is curable, provide palliative care for patients in need, and monitor and manage for results.

Prevent what is preventable, cure what is curable, provide palliative care for patients in need, and monitor and manage for results. Proposed PAHO Plan of Action for Cancer Prevention and Control 2008 2015 Prevent what is preventable, cure what is curable, provide palliative care for patients in need, and monitor and manage for results.

More information

Emphysema. Introduction Emphysema is a type of chronic obstructive pulmonary disease, or COPD. COPD affects about 64 million people worldwide.

Emphysema. Introduction Emphysema is a type of chronic obstructive pulmonary disease, or COPD. COPD affects about 64 million people worldwide. Emphysema Introduction Emphysema is a type of chronic obstructive pulmonary disease, or COPD. COPD affects about 64 million people worldwide. Emphysema involves damage to the air sacs in the lungs. This

More information

Key Staff Members EXECUTIVE TEAM Nancy Price Mendenhall, MD Medical Director Stuart Klein, MHA Executive Director Zuofeng Li, DSc Physics Director

Key Staff Members EXECUTIVE TEAM Nancy Price Mendenhall, MD Medical Director Stuart Klein, MHA Executive Director Zuofeng Li, DSc Physics Director Key Staff Members EXECUTIVE TEAM Nancy Price Mendenhall, MD Medical Director A University of Florida College of Medicine faculty member since 1985, Dr. Mendenhall served as the chair of the Department

More information

written by Harvard Medical School COPD It Can Take Your Breath Away www.patientedu.org/copd

written by Harvard Medical School COPD It Can Take Your Breath Away www.patientedu.org/copd written by Harvard Medical School COPD It Can Take Your Breath Away www.patientedu.org/copd What Is COPD? COPD stands for chronic obstructive pulmonary disease. There are two major diseases included in

More information

Small cell lung cancer

Small cell lung cancer Small cell lung cancer Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. The lungs are a pair of cone-shaped breathing organs that are found within

More information

Low-dose CT Imaging. Edgar Fearnow, M.D. Section Chief, Computed Tomography, Lancaster General Hospital

Low-dose CT Imaging. Edgar Fearnow, M.D. Section Chief, Computed Tomography, Lancaster General Hospital Lung Cancer Screening with Low-dose CT Imaging Edgar Fearnow, M.D. Section Chief, Computed Tomography, Lancaster General Hospital Despite recent declines in the incidence of lung cancer related to the

More information

Tobacco Smoking as a Possible Etiologic Factor

Tobacco Smoking as a Possible Etiologic Factor Tobacco Smoking as a Possible Etiologic Factor in Bronchiogenic Carcinoma A Study of Six Hundred and Eighty-Four Proved Cases Ernest L. Wynder and Evarts A. Graham, M.D. St. Louis General Increase.\p=m-\Thereis

More information

Measurement in Epidemiology: Frequency, Association, and Impact

Measurement in Epidemiology: Frequency, Association, and Impact Measurement in Epidemiology: Frequency, Association, and Impact Mayfong Mayxay M.D., Ph.D. (Trop Med) GFMER - WHO - UNFPA - LAO PDR Training Course in Reproductive Health Research Vientiane, 12 October

More information

Emerging evidence that the ban on asbestos use is reducing the occurrence of pleural mesothelioma in Sweden

Emerging evidence that the ban on asbestos use is reducing the occurrence of pleural mesothelioma in Sweden 596500SJP0010.1177/1403494815596500B. Järvholm and A. BurdorfAsbestos ban reduces mesothelioma incidence research-article2015 Scandinavian Journal of Public Health, 1 7 Original Article Emerging evidence

More information

Lung cancer and asbestos

Lung cancer and asbestos Lung cancer and asbestos Bureau Veritas Training Bill Sanderson For the benefit of business and people To begin with.. There are known knowns, that is there are things we know that we know. There are known

More information

Guidelines for Cancer Prevention, Early detection & Screening. Prostate Cancer

Guidelines for Cancer Prevention, Early detection & Screening. Prostate Cancer Guidelines for Cancer Prevention, Early detection & Screening Prostate Cancer Intervention Comments & Recommendations For primary prevention, it has been suggested that diets low in meat & other fatty

More information

Hospital to Physician Office to Home: A Respiratory Led Program Across the Continuum of Care

Hospital to Physician Office to Home: A Respiratory Led Program Across the Continuum of Care Hospital to Physician Office to Home: A Respiratory Led Program Across the Continuum of Care Charley P. Starnes, RRT, RCP Clinical Respiratory Specialist- COPD Education Important Milestones July 2011-

More information

MEDICAL BREAKTHROUGHS RESEARCH SUMMARY

MEDICAL BREAKTHROUGHS RESEARCH SUMMARY TOPIC: Using Video to Kill Lung Cancer REPORT: MB #4111 MEDICAL BREAKTHROUGHS RESEARCH SUMMARY BACKGROUND: Lung cancer is the second most common cancer in both men and women, excluding skin cancer. About

More information

Travis Baggett, MD, MPH Jessie M. Gaeta, MD Jennifer Brody, MD, MPH Boston Health Care for the Homeless Program

Travis Baggett, MD, MPH Jessie M. Gaeta, MD Jennifer Brody, MD, MPH Boston Health Care for the Homeless Program Travis Baggett, MD, MPH Jessie M. Gaeta, MD Jennifer Brody, MD, MPH Boston Health Care for the Homeless Program Substance- attributable mortality Presentation of the data Implications for our model of

More information

Smoke-Free Environments

Smoke-Free Environments Smoke-Free Environments A Booklet For Day Care Providers Clean AirCouncil Smoke-Free Environments Table of Contents Introduction A Letter From Clean Air Council....................... 1 Information on

More information

Measure Title FOLLOW UP EXAMINATION AFTER DIAGNOSIS AND TREATMENT OF SKIN CANCERS Disease State Cancer Indicator Classification Disease Management

Measure Title FOLLOW UP EXAMINATION AFTER DIAGNOSIS AND TREATMENT OF SKIN CANCERS Disease State Cancer Indicator Classification Disease Management Client HMSA: PQSR 2009 Measure Title FOLLOW UP EXAMINATION AFTER DIAGNOSIS AND TREATMENT OF SKIN CANCERS Disease State Cancer Indicator Classification Disease Management Strength of Recommendation Organizations

More information

Survey on the Mortality from Malignant Tumors of Female Asbestos Spinning Workers

Survey on the Mortality from Malignant Tumors of Female Asbestos Spinning Workers Table of Contents WS-E-12 Xing Zhang Survey on the Mortality from Malignant Tumors of Female Asbestos Spinning Workers Xing Zhang 1, Tong-da Sun 2, Nan-feng Shi 2, Li-qiu Zhu 1, Kenji Morinaga 3 1 Institute

More information

PROMOTING SMOKE-FREE POLICIES A GUIDE FOR WORKPLACES PROMOTING SMOKE-FREE POLICIES A GUIDE FOR WORKPLACES

PROMOTING SMOKE-FREE POLICIES A GUIDE FOR WORKPLACES PROMOTING SMOKE-FREE POLICIES A GUIDE FOR WORKPLACES PROMOTING SMOKE-FREE POLICIES A GUIDE FOR WORKPLACES PROMOTING SMOKE-FREE POLICIES A GUIDE FOR WORKPLACES The space around your workplace tells a lot about the kind of company you are. Making your business

More information

Tobacco Control in India

Tobacco Control in India Tobacco Control in India K R Thankappan MD, MPH Professor Achutha Menon Centre for Health Science Studies Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, India

More information

Defending the Rest Basics on Lung Cancer, Other Cancers and Asbestosis: Review of the B-Read and Pulmonary Function Testing

Defending the Rest Basics on Lung Cancer, Other Cancers and Asbestosis: Review of the B-Read and Pulmonary Function Testing Defending the Rest Basics on Lung Cancer, Other Cancers and Asbestosis: Review of the B-Read and Pulmonary Function Testing OTHER CANCERS November 2013 Bruce T. Bishop Nancy E. Leary Willcox & Savage 440

More information

MONSANTO COMPANY (ama SOLUTIA INCORPORATED) ANNISTON, CALHOUN COUNTY, ALABAMA FEBRUARY 14,2000

MONSANTO COMPANY (ama SOLUTIA INCORPORATED) ANNISTON, CALHOUN COUNTY, ALABAMA FEBRUARY 14,2000 ........-. Health Consultation Public Comment Release Evaluation of Soil, Blood '& Air Data from Anniston, Alabama ' MONSANTO COMPANY (ama SOLUTIA INCORPORATED) ANNISTON, CALHOUN COUNTY, ALABAMA CERCLIS

More information

A guide for the patient

A guide for the patient Understanding series LUNG CANCER CLINICAL TRIALS 1-800-298-2436 LungCancerAlliance.org A guide for the patient TABLE OF CONTENTS The Basics What is a Clinical Trial?...3 Types of Clinical Trials... 3 Phases

More information

An Update on Lung Cancer Diagnosis

An Update on Lung Cancer Diagnosis An Update on Lung Cancer Diagnosis Dr Michael Fanning MBBS FRACGP FRACP RESPIRATORY AND SLEEP PHYSICIAN Mater Medical Centre Outline Risk factors for lung cancer Screening for lung cancer Radiologic follow-up

More information

Unit 14: The Question of Causation

Unit 14: The Question of Causation Unit 14: The Question of Causation Prerequisites Even though there are no specific mathematical or statistical prerequisites, the ideas presented are too sophisticated for most pre-secondary students.

More information

Asbestos Health Risks. Dr Andrew Pengilley Acting Chief Health Officer

Asbestos Health Risks. Dr Andrew Pengilley Acting Chief Health Officer Asbestos Health Risks Dr Andrew Pengilley Acting Chief Health Officer Asbestos Asbestos is a name given to several different fibrous minerals Three main commercial types are Chrysotile (white asbestos)

More information

Impact of a nurse telephone intervention among high cardiovascular risk health fair participants. Lisa H. Jensen, BSN, RN Colorado Prevention Center

Impact of a nurse telephone intervention among high cardiovascular risk health fair participants. Lisa H. Jensen, BSN, RN Colorado Prevention Center Impact of a nurse telephone intervention among high cardiovascular risk health fair participants Lisa H. Jensen, BSN, RN Colorado Prevention Center Co-authors Bonnie Leaman-Castillo PhD, Behavioral Scientist

More information

Screening Tools Help Guide: Fagerstrom Tolerance Scale

Screening Tools Help Guide: Fagerstrom Tolerance Scale Screening Tools Help Guide: Fagerstrom Tolerance Scale Reliability and Validity Pomerleau CS, Carton SM, Lutzke ML, Flessland KA, Pomerleau OF. Reliability of the Fagerstrom Tolerance Questionnaire and

More information

Asbestos Related Diseases

Asbestos Related Diseases Asbestos Related Diseases Asbestosis Mesothelioma Lung Cancer Pleural Disease Asbestosis and Mesothelioma (LUNG CANCER) Support Group 1800 017 758 www.amsg.com.au ii Helping you and your family through

More information

Better Living with Obstructive Pulmonary Disease A Patient Guide

Better Living with Obstructive Pulmonary Disease A Patient Guide Better Living with Obstructive Pulmonary Disease A Patient Guide Second Edition November 2012 Queensland Health The State of Queensland (Queensland Health) and The Australian Lung Foundation 2012 a Better

More information

Wittenoom Professor Eric Saint

Wittenoom Professor Eric Saint HISTORICAL AND CURRENT LEGAL ISSUES RELATING TO OCCUPATIONAL CAUSES OF RESPIRATORY MALIGNANCIES Wittenoom Professor Eric Saint Wounds go septic for no other reason than the fact that all they have is this

More information

Emergency Scenario. Chest Pain

Emergency Scenario. Chest Pain Emergency Scenario Chest Pain This emergency scenario reviews chest pain in a primary care patient, and is set up for roleplay and case review with your staff. 1) The person facilitating scenarios can

More information

Click to edit Master title style

Click to edit Master title style O ral Cancer - so much research, Click to edit Master title style so little progress-why? Click to edit Master text styles Second Level Christopher Squier Third Level Department of O ral Pathology Fourth

More information

The Liver and Alpha-1. Antitrypsin Deficiency (Alpha-1) 1 ALPHA-1 FOUNDATION

The Liver and Alpha-1. Antitrypsin Deficiency (Alpha-1) 1 ALPHA-1 FOUNDATION The Liver and Alpha-1 Antitrypsin Deficiency (Alpha-1) 1 ALPHA-1 FOUNDATION What Is Alpha-1 Antitrypsin Deficiency? Alpha-1 is a condition that may result in serious lung disease in adults and/or liver

More information