Target audience. Physicians and other health care professionals working in reproductive health centres.

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1 Mail to: Meridiano Congress International Att: Denise Rizzitelli Via Mentana 2/B Rome Italy Mail to: Meridiano Congress International Att: Denise Rizzitelli Via Mentana 2/B Rome Italy

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3 Aim of the conference In the field of reproductive health, two needs are emerging that apparently conflict. On one side, research is proposing continuous innovations to be implemented in daily procedures, on the other hand the demand for infertility treatment is increasing all over the world. The key point of conflict between these two aspects is cost: innovation requires, at least in an early phase, relevant investments, and the widening of ART to geographical areas with lower average incomes require careful evaluations of the cost/benefit balance. The aim of this conference, which follows the previous two successfully organized by Paolo Levi Setti in 2003 and 2008 together with Serono Symposia International Foundation, is to provide participants with overviews of the most innovative procedures that will be proposed in ART in near future and the background needed to offer the most up-to-date infertility treatment, according to the different local realities specialists are dealing with. The Conference is organized in four session s e 2 key note lectures. Aim of this conference, in the intention of the Scientific Organizer, is to give special importance and space to the contribution of young National and International Scientists whose selected abstract will be briefly orally presented (5 minutes presentation and 5 minutes discussion) in the main program. Therefore abstracts related to the main topics of the conference are highly welcomed and must be sent by May 1, 2011 for peer review selection. All the accepted papers, as for the previous two editions, as well as in this edition all selected abstracts, will be published as a special number of Placenta. Learning objectives Attending the conference, participants will acquire: Updates on innovative surgical procedure applied to reproductive health. Overviews of key factors of embryo development. Criteria to optimize ART outcomes, consistent with the reality in which they operate. Target audience Physicians and other health care professionals working in reproductive health centres. 1

4 Accreditation Serono Symposia International Foundation ( will submit this program A Window into the Reproductive Era Research, Milan, Italy, 30 September 1 October, 2011 for accreditation by the European Accreditation Council for Continuing Medical Education (EACCME), the Royal College of Physicians and the Italian Ministry of Health. All Serono Symposia International Foundation programs are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. All the Serono Symposia International Foundation programs are made possible thanks to the unrestricted Educational grant received from: Centre d Esclerosi Multiple de Catalunya, Vall d'hebron University Hospital, ComtecMed, Congrex Sweden, Congrex Switzerland, Cryo-Save, Datanalysis, Esaote, European Society of Endocrinology, Fundación IVI, ISFP International Society for Fertility Preservation, ISMH International Society of Men s Health, K.I.T.E., Merck Serono, Ministry of Health of the State of Israel, University of Catania. 2

5 Scientific Secretariat Serono Symposia International Foundation Salita di San Nicola da Tolentino, 1/b Rome, Italy Project Manager: Francesca Pellegrino Tel.: Fax: Serono Symposia International Foundation is a Swiss Foundation with headquarters in 14, rue du Rhône, 1204 Geneva, Switzerland Organizing secretariat Meridiano Congress International Via Mentana, 2/B Rome, Italy Congress coordinator: Denise Rizzitelli Tel.: Fax: d.rizzitelli@meridiano.it 3

6 Scientific Organizer Paolo Emanuele Levi Setti Department of Gynecology and Reproductive Medicine IRCCS Istituto Clinico Humanitas, Rozzano, Milan, Italy International Scientific Committee Claus Yding Andersen, Denmark Nicole Noyes, USA Pasquale Patrizio, USA Francoise Shenfield, UK National Scientific Committee Andrea Borini, Italy Carlo Bulletti, Italy Edgardo Somigliana,Italy Filippo Ubaldi, Italy Local Organizing Committee Elena Albani,Italy Annamaria Baggiani,Italy Luciano Negri, Italy Elena Zannoni, Italy Placenta Guest Editors Irene Cetin, Italy Paolo Emanuele Levi Setti, Italy 4

7 List of faculty members

8 Elena Albani Department of Reproductive Medicine Humanitas Clinical Institute, IRCCS, Rozzano Milan, Italy Claus Yding Andersen Laboratory of Reproductive Biology University Hospital of Copenhagen Copenhagen, Denmark Paola Anserini Department of Obstetrics and Gynaecology University of Genoa S. Martino Hospital Genoa, Italy Amir Arav Animal Science ARO Israel & Core Dynamics Israel Ness Ziona, Israel Daniela Bettio Cytogenetic Laboratory Operative Unit of Clinical Investigations Humanitas Clinical Institute, IRCCS, Rozzano Milan, Italy Andrea Borini Tecnobios Procreazione Centre for Reproductive Health Bologna, Italy Carlo Bulletti Physiopathology of Reproduction Unit Cattolica s Cervesi General Hospital University of Bologna in Rimini Rimini, Italy Irene Cetin Department of Clinical Sciences Hospital Luigi Sacco University of Milan Milan, Italy 6

9 Ettore Cittadini CMRA Department of Obstetrics and Gynaecology Palermo, Italy Elisabetta Coccia Department Gynaecology, Perinatology and Human Reproduction University of Florence Florence, Italy Lucia De Santis IVF Laboratory, Department of Obstetrics and Gynaecology University Vita-Salute, S. Raffaele Hospital Milan, Italy Joy Delhanty Department of Obstetrics and Gynaecology University College London London, UK Tommaso Falcone Obstetrics, Gynecology and Women's Health Institute Cleveland, OH, USA Luigi Fedele Department of Obstetrics and Gynecology University of Milan Fondazione Policlinico Mangiagalli e Regina Elena Istituto Luigi Mangiagalli Milan, Italy Enrico Ferrazzi Obstetric and Gynecologic Clinic University of Milan Buzzi Hospital Milan, Italy Robert Fischer Fertility centre Hamburg, Germany 7

10 Paolo Emanuele Levi Setti Department of Gynecology and Reproductive Medicine Humanitas Clinical Institute, IRCCS, Rozzano Milan, Italy Markus Montag Department of Gynecological Endocrinology and Reproductive Medicine University of Bonn Bonn, Germany Zsolt Peter Nagy Reproductive Biology Associates Atlanta, GA, USA Nicole Noyes Division of Reproductive Endocrinology New York University School of Medicine New York, NY, USA Michael Paidas Yale Women and Children's Center for Blood Disorders Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine New Haven, CT, USA Antonio Palagiano Chamber of Deputies Rome, Italy Roberto Palermo Associazione Medici e Biologi per la Riproduzione Assisitita Palermo, Italy Pasquale Patrizio Yale University Fertility Center New Haven, CT, USA Guido Ragni Mangiagalli Clinic Milan, Italy 8

11 Guglielmo Ragusa San Paolo Hospital Milano, Italy Renee Reijo Pera Institute for Stem Cell Biology and Regenerative Medicine Department of Obstetrics and Gynecology Stanford University School of Medicine Stanford, CA, USA Laura Rienzi G.EN.E.R.A Centre for Reproductive Medicine Clinica Valle Giulia Rome, Italy Giulia Scaravelli National Institute of Health, National Art Register National Centre for Epidemiology Surveillance and Health Promotion Rome, Italy Francoise Shenfield University College Hospitals Elizabeth Garrett Anderson London, UK Carlos Simón Vallés Department of Obstetrics & Gynecology Valencia University Instituto Valenciano de Infertilidad (IVI) Prince Felipe Research Centre (CIPF) & Valencia Stem Cell Bank (CIPF) Valencia, Spain Edgardo Somigliana Department of Obstetrics & Gynecology Fondazione Cà Granda, Ospedale Maggiore Policlinico Milan, Italy Togas Tulandi Department of Obstetrics and Gynecology McGill University Montreal, Quebec, Canada 9

12 Filippo Ubaldi G.EN.E.R.A. Centre for Reproductive Medicine Valle Giulia Clinic Rome, Italy Hilde Van de Velde Centre for Reproductive Medicine UZ Brussel Brussels, Belgium Joris Vermeesh Centre for Human Genetics University Hospital Leuven Leuven, Belgium Domenico Vitobello Department of Gynecology Humanitas Clinical Institute, IRCCS Rozzano, Milan, Italy Dagan Wells University of Oxford Nuffield Department of Obstetrics and Gynaecology Women's Centre John Radcliffe Hospital Oxford, UK Patrick Willems Genetic Diagnostic Network (GENDIA) Antwerp, Belgium 10

13 Scientific program

14 Scientific program Friday - September 30, Registration Scientific Organizer welcome Paolo Emanuele Levi Setti, Italy SSIF Welcome Robert Fischer, Germany Session I Innovative Surgical Procedures in ART Chairmen: Elisabetta Coccia, Italy; Luigi Fedele, Italy L1: Gynecological fertility sparing surgery Domenico Vitobello, Italy L2: Robotics indications in reproductive surgery: pros and cons Tommaso Falcone, USA L3: Innovative approaches to endometriosis surgery Edgardo Somigliana, Italy L4: What s left of reproductive surgery? Togas Tulandi, Canada L5: New ideas in myoma s surgery Carlo Bulletti, Italy Discussion Coffee break Key note Lecture Chairmen: Paola Anserini, Italy; Filippo Ubaldi, Italy KNL1: Benefit and risk of application of european tissue management regulation in ART Giulia Scaravelli, Italy 12

15 Session II Innovation in ART Laboratories Chairmen: Elena Albani, Italy; Andrea Borini, Italy L6: New culture devices in ART Laura Rienzi, Italy L7: Which scores are relevant for improving ART success? Markus Montag, Germany L8: A review of the promises and pitfalls of oocyte and embryo metabolomics Peter Nagy, USA L9: Non invasive imaging of human embryos to predict competence Renee Reijo Pera, USA Discussion Lunch 13

16 Session III Exploring the chaos: the early stages of embryo development Chairmen: Claus Yding Andersen, Denmark; Daniela Bettio, Italy L10: Array CGH is the key to understand oocyte developmental competence Dagan Wells, UK L11: Is chromosome instability common feature of human embryos? New array approaches to explore single cells genomes Joris Vermeesch, Belgium L12: Cell (pre)-destiny in the human preimplantation embryo and implications for IVF and PGS Hilde Van de Velde, Belgium L13: Is the polar body approach best for pre-implantation genetic screening? Joy Delhanty, UK L14: Whole genome sequencing in a prenatal setting Patrick Willems, Belgium Discussion Coffee break Abstracts selected for oral presentation Chairmen: Lucia De Santis, Italy; Guglielmo Ragusa, Italy Conclusions 14

17 Scientific program Saturday - October 1, 2011 Session IV Present and Future of ART Chairmen: Roberto Palermo, Italy; Guido Ragni, Italy L15: Consenting for the hot topics in reproductive care Francoise Shenfield, UK L16: The future of IVF: the next 5 years Pasquale Patrizio, USA L17: Fertility preservation: a reappraisal Nicole Noyes, USA L18: Lyophilization and rehydratation of cells Amir Arav, Israel L19: Work-up of repetitive implantation failures Michael Paidas, USA Discussion Coffee break Abstracts selected for oral presentation Chairmen: Ettore Cittadini, Italy; Antonio Palagiano, Italy Key note Lecture Chairmen: Irene Cetin, Italy; Enrico Ferrazzi, Italy KLN 2: How endometrial secretomics can help in predicting implantation Carlos Simón Vallés, Spain Conclusions Paolo Emanuele Levi Setti 15

18 General information Venue Congress Center Humanitas Clinical Institute Via Manzoni Rozzano (Milan) - Italy Language The official language of this conference will be English Registration fee The registration fee is Euro 350,00. For students, paramedical staff and trainees, the registration fee is Euro 300,00. Note: for students, paramedical staff and trainees, a letter certifying status must accompany registration. This fee includes: all plenary sessions congress folder working luncheons coffee breaks certificate of attendance congress dinner (September 30, 2011) * If you require special assistance (wheelchair, auxiliary aids) or special dietary requirements, please indicate and we will contact you. Yes follow us on Personal data treatment - Informative document In compliance with the article 13 of Italian Legislative Decree n. 196, 30 June 2003, we inform you that your personal data will be processed, with or without the use of electronic or automated means, via suitable tools that will guarantee security and confidentiality. Personal data from you supplied will be communicated to Continuing Medical Education Accreditation Authorities, to agencies that will take care of the whole accreditation process and agencies that will take care of the logistics of the event; should we not receive the below requested data, we will not be able to process your registration to the event. At anytime you may exercise your rights as laid down in the art. 7 of Italian Legislative Decree n. 196, 30 June 2003 of the Italian Law, by contacting the Data Controller Serono Symposia International Foundation (Salita di San Nicola da Tolentino, 1/b Rome - Italy) in the person of Data Processor, Michèle Piraux. 16

19 Call for Abstracts The Scientific Committee invites the submission of abstracts to be considered for oral presentation. A special scientific award will be assigned to the best 3 oral presentations (2000 Euros to the first, 1000 Euros to the second and 500 Euros to the third classified). Authors are requested to send the abstract by to the following address: francesca.pellegrino@seronosymposia.org Deadline for submission: May 1, 2011 Abstracts must be written in English. Abstracts should be 1 page in length and include the title of the presentation, the author s names, the name of the institution, the city and country. The title of the abstract and the following Introduction should be informative and short. The contents of Material and Methods, Results and Conclusions should provide sufficient information. Use font size 12, Times New Roman font type and line spacing 1.5. All accepted abstracts will be published as a supplement to the journal "Placenta" and they will be part of the oral presentations in the conference program. Proceedings The Proceedings of this conference will be published as a Supplement to the journal Placenta 17

20 Location Milan is to be considered Italy s door to Europe. Financial capital of Italy with its stock exchange and large industrial sector, Milan is not just famous for its fashion. Historic sites such as the magnificent gothic Duomo Cathedral as well as Leonardo da Vinci s Last Supper, housed at the Church of Santa Maria delle Grazie, are musts for every visitor. Not to mention La Scala, probably the world s most illustrious Opera House. Splendid also is nearby Lake Como. Milan has two airports, Linate and Malpensa, both of which connected to all the major European capitals. Milan is also easily reached by rail and motorway. The congress will take place at the Istituto Clinico Humanitas, located in Rozzano, about 10 km from the city center of Milan. You can reach Humanitas using: Public transportation: If you prefer to use public transport, please find below some useful information. Approximate time to reach Humanitas from Milan city center is minutes. Underground (Green line) from the city center direction Famagosta. Stop Famagosta. Bus AMP (passes every minutes) direction Rozzano. Stop Humanitas. Tram No. 15 from the city center - direction Rozzano. Stop Rozzano (last stop). Bus AMP (passes every minutes) direction Rozzano. Stop Humanitas. 18

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24 Registration form Serono Symposia International Foundation A window into the Reproductive Era Research Milan, Italy - September 30, October Last Name First Name Academic Title Institution Department Address City Province/Country Postal Code Office Telephone Number(s) Mobile Telephone Number(s) Fax Number Registration Fee Full registration: 300 before July 1, 2011 and 350 after that date. Students, paramedical staff & trainees: 250 before July 1, 2011 and 300 after that date. Note: For students, paramedical staff and trainees, a letter certifying status must accompany registration. CONGRESS DINNER: I will attend the Congress Dinner on September 30, 2011 yes no The cost of the Congress Dinner on September 30, 2011 is included in the Registration Fee (1 seat). If you want any accompanying persons to attend the dinner, please fill in the space below: I want to buy Congress Dinner Ticket(s) for Accompanying Persons at the cost of 60 per person: Number of tickets: Total to be charged: Please note that only a limited number of registrations will be accepted. Payment Payment by Bank Transfer headed to: Meridiano viaggi e turismo s.r.l" BANCA INTERMOBILIARE S.p.A FILIALE DI ROMA - VIA DONIZETTI, ROME - ITALY Account number: IBAN: IT11 C SWIFT: BIMTITTTXXX Payment by Credit Card Charge to the following Credit Card (Credit Card commission Fee 3,5%): MasterCard/EuroCard Visa Card Number Exp. Date Card Holder Name (PLEASE PRINT) Card Holder s Signature Date ONLY REGISTRATION FORMS ACCOMPANIED WITH PAYMENT CAN BE PROCESSED Mail to: Denise Rizzitelli c/o Meridiano Congress International Via Mentana, 2/B Rome, Italy T F d.rizzitelli@meridiano.it All completed Registration forms will be acknowledged by or fax. Cancellations must be received in writing by July 1, After this date full penalty will be applied in case of cancellations

25 Mail to: Meridiano Congress International Att: Denise Rizzitelli Via Mentana 2/B Rome Italy Mail to: Meridiano Congress International Att: Denise Rizzitelli Via Mentana 2/B Rome Italy

26 Hotel accommodation form Serono Symposia International Foundation A window into the Reproductive Era Research Milan, Italy - September 30, October Last Name First Name Academic Title Institution Department Address City Province/Country Postal Code Office Telephone Number(s) Mobile Telephone Number(s) Fax Number For hotel reservation, please return the completed form with full prepayment of the requested nights. Hotel Reservation forms without prepayment cannot be processed. DEADLINE FOR RESERVATIONS: JULY 1, 2011 Reservation after this date are not guaranteed and will be made on a space-available bases. Hotel dei Cavalieri (4 stars) located in Milan city center Double room for single use: 265 per night Check in date: Check out date: (N of nights: ) Rates include breakfast and city taxes. Payment Payment by Bank Transfer headed to: Meridiano viaggi e turismo s.r.l" BANCA INTERMOBILIARE S.p.A FILIALE DI ROMA - VIA DONIZETTI, ROME - ITALY Account number: IBAN: IT11 C SWIFT: BIMTITTTXXX Payment by Credit Card Charge to the following Credit Card (Credit Card commission Fee 3,5%): MasterCard/EuroCard Visa Card Number Exp. Date Card Holder Name (PLEASE PRINT) Card Holder s Signature Date Mail to: Denise Rizzitelli c/o Meridiano Congress International Via Mentana, 2/B Rome, Italy T F d.rizzitelli@meridiano.it Once you confirm rooms to Meridiano, full penalty will be applied in case of cancellation.

27 Mail to: Meridiano Congress International Att: Denise Rizzitelli Via Mentana 2/B Rome Italy Mail to: Meridiano Congress International Att: Denise Rizzitelli Via Mentana 2/B Rome Italy

28 Mail to: Meridiano Congress International Att: Denise Rizzitelli Via Mentana 2/B Rome Italy Mail to: Meridiano Congress International Att: Denise Rizzitelli Via Mentana 2/B Rome Italy

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